Arhgef11 (Rho guanine nucleotide exchange factor 11) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Arhgef11 (Rho guanine nucleotide exchange factor 11) Rattus norvegicus
Analyze
Symbol: Arhgef11
Name: Rho guanine nucleotide exchange factor 11
RGD ID: 619705
Description: Enables guanyl-nucleotide exchange factor activity. Involved in positive regulation of L-glutamate import across plasma membrane. Predicted to be located in nucleoplasm and plasma membrane. Predicted to be active in cytoplasm. Orthologous to human ARHGEF11 (Rho guanine nucleotide exchange factor 11); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: glutamate transporter EAAT4 associated protein 48; Gtrap48; Rho guanine nucleotide exchange factor (GEF) 11; RhoGEF glutamate transport modulator GTRAP48
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: Arhgef11em4Mcwi   Arhgef11em5Mcwi  
Genetic Models: SS-Arhgef11em5Mcwi SS-Arhgef11em4Mcwi
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82175,372,269 - 175,493,852 (+)NCBIGRCr8
mRatBN7.22173,074,383 - 173,195,962 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2173,074,368 - 173,196,010 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2180,224,015 - 180,343,253 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02178,246,357 - 178,365,598 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02172,835,607 - 172,955,106 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02186,979,850 - 187,102,523 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2186,980,793 - 187,101,768 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02206,384,799 - 206,507,431 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42179,676,236 - 179,796,785 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12179,626,341 - 179,746,891 (+)NCBI
Celera2167,024,592 - 167,144,568 (+)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,IEA,ISO)
membrane  (IEA)
nucleoplasm  (IEA,ISO)
plasma membrane  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Recognition of the activated states of Galpha13 by the rgRGS domain of PDZRhoGEF. Chen Z, etal., Structure. 2008 Oct 8;16(10):1532-43. doi: 10.1016/j.str.2008.07.009.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Increased PDZ-RhoGEF/RhoA/Rho kinase signaling in small mesenteric arteries of angiotensin II-induced hypertensive rats. Hilgers RH, etal., J Hypertens. 2007 Aug;25(8):1687-97.
5. Modulation of the neuronal glutamate transporter EAAT4 by two interacting proteins. Jackson M, etal., Nature 2001 Mar 1;410(6824):89-93.
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10026210   PMID:15755723   PMID:18226120   PMID:20739613   PMID:22987919   PMID:23696743   PMID:24106280   PMID:26172442   PMID:31612150   PMID:32148127  


Genomics

Comparative Map Data
Arhgef11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82175,372,269 - 175,493,852 (+)NCBIGRCr8
mRatBN7.22173,074,383 - 173,195,962 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2173,074,368 - 173,196,010 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2180,224,015 - 180,343,253 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02178,246,357 - 178,365,598 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02172,835,607 - 172,955,106 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02186,979,850 - 187,102,523 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2186,980,793 - 187,101,768 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02206,384,799 - 206,507,431 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42179,676,236 - 179,796,785 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12179,626,341 - 179,746,891 (+)NCBI
Celera2167,024,592 - 167,144,568 (+)NCBICelera
Cytogenetic Map2q34NCBI
ARHGEF11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381156,934,840 - 157,046,903 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1156,934,840 - 157,045,742 (-)EnsemblGRCh38hg38GRCh38
GRCh371156,904,632 - 157,016,695 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361155,171,256 - 155,281,786 (-)NCBINCBI36Build 36hg18NCBI36
Build 341153,717,705 - 153,828,235NCBI
Celera1129,975,863 - 130,086,340 (-)NCBICelera
Cytogenetic Map1q23.1NCBI
HuRef1128,263,003 - 128,403,804 (-)NCBIHuRef
CHM1_11158,301,064 - 158,411,558 (-)NCBICHM1_1
T2T-CHM13v2.01156,071,681 - 156,183,721 (-)NCBIT2T-CHM13v2.0
Arhgef11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39387,524,855 - 87,645,346 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl387,524,866 - 87,645,341 (+)EnsemblGRCm39 Ensembl
GRCm38387,617,548 - 87,738,039 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl387,617,559 - 87,738,034 (+)EnsemblGRCm38mm10GRCm38
MGSCv37387,422,673 - 87,541,955 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36387,704,678 - 87,823,960 (+)NCBIMGSCv36mm8
Celera387,655,238 - 87,774,229 (+)NCBICelera
Cytogenetic Map3F1NCBI
cM Map338.22NCBI
Arhgef11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555452,989,774 - 3,097,003 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555452,988,676 - 3,099,159 (-)NCBIChiLan1.0ChiLan1.0
ARHGEF11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2192,797,589 - 92,910,122 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1192,532,333 - 92,644,715 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01132,277,514 - 132,390,041 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11136,100,575 - 136,210,253 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1136,101,732 - 136,208,896 (-)Ensemblpanpan1.1panPan2
ARHGEF11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1741,011,956 - 41,098,134 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl741,011,830 - 41,097,487 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha740,499,160 - 40,585,236 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0740,874,361 - 40,960,526 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl740,874,219 - 40,960,633 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1740,656,641 - 40,742,722 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0740,709,544 - 40,795,782 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0740,992,902 - 41,079,222 (+)NCBIUU_Cfam_GSD_1.0
Arhgef11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505827,036,196 - 27,147,213 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365806,067,429 - 6,177,601 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365806,066,577 - 6,177,595 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARHGEF11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl493,046,770 - 93,160,084 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1493,045,533 - 93,160,756 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24101,684,353 - 101,732,762 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ARHGEF11
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1206,825,331 - 6,935,110 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl206,883,815 - 6,933,961 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660386,100,669 - 6,210,618 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arhgef11
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248852,043,672 - 2,171,491 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248852,042,718 - 2,171,368 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Arhgef11
377 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:80
Count of miRNA genes:70
Interacting mature miRNAs:79
Transcripts:ENSRNOT00000020717
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242804607182042367Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)243154682202446871Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)243154682202446871Rat
1354601Slep1Serum leptin concentration QTL 15.39blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)243171017184114403Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)246123260202447032Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)256043031202447032Rat
1298080Bp163Blood pressure QTL 1630.02arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118275202447032Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)274786664206665859Rat
61374Edpm2Estrogen-dependent pituitary mass QTL 24.420.86pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)276539322202447032Rat
1581569Uae32Urinary albumin excretion QTL 320.0001urine protein amount (VT:0005160)urine albumin excretion rate (CMO:0000757)278665619219826953Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)278665619249053267Rat
8662832Vetf7Vascular elastic tissue fragility QTL 73.5aorta elastin amount (VT:0003905)aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)281689826221035911Rat
1354622Kidm16Kidney mass QTL 163kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)281754530222436696Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)281754530227146641Rat
631507Bp105Blood pressure QTL 1050.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2112456140212696837Rat
634308Sach6Saccharin preference QTL 64.9taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)2112456140212696837Rat
1359030Bp277Blood pressure QTL 277arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2114837527185876470Rat
1359030Bp277Blood pressure QTL 277arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2114837527185876470Rat
1578648Bss11Bone structure and strength QTL 114.7femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)2114837527211674221Rat
1554319Bmd2Bone mineral density QTL 213.40.0001lumbar vertebra area (VT:0010570)lumbar vertebra cross-sectional area (CMO:0001689)2114837675212549332Rat
6907363Bp357Blood pressure QTL 3574.10.002arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2129540907174540907Rat
1300165Rf9Renal function QTL 93.28kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)2133914684202447032Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)2135552573202446871Rat
1298076Bp166Blood pressure QTL 1660.0009arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2136445150202447032Rat
1581502Esta3Estrogen-induced thymic atrophy QTL 3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)2136916935189599348Rat
1359022Ppulsi1Prepulse inhibition QTL 13.63prepulse inhibition trait (VT:0003088)acoustic startle response measurement (CMO:0001519)2136916935213594495Rat
1331794Bp202Blood pressure QTL 2023.66819arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2141194931223265385Rat
1331805Cm29Cardiac mass QTL 293.50746heart mass (VT:0007028)heart wet weight (CMO:0000069)2141194931223265385Rat
71113Cari2Carrageenan-induced inflammation QTL 22.70.009hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)2141596551202447032Rat
724568Uae13Urinary albumin excretion QTL 134.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)2143157029210020885Rat
10043136Iddm54Insulin dependent diabetes mellitus QTL 543.40.0001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2143657411190602963Rat
10043136Iddm54Insulin dependent diabetes mellitus QTL 543.40.0001blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)2143657411190602963Rat
6903312Bw112Body weight QTL 1123.20.0013body mass (VT:0001259)body weight (CMO:0000012)2143657569184114274Rat
61401Niddm2Non-insulin dependent diabetes mellitus QTL 24.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2144599348189599348Rat
1598833Bp295Blood pressure QTL 2953.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2147798556192798556Rat
1641925Alcrsp2Alcohol response QTL 2response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561221167075Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561249053267Rat
1598805Memor8Memory QTL 83exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)2150341585189039377Rat
631501Bp101Blood pressure QTL 1012.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2150341684202446871Rat
2301966Bp322Blood pressure QTL 3223.58arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2150540301202447032Rat
1354609Niddm62Non-insulin dependent diabetes mellitus QTL 624.720.000006insulin secretion trait (VT:0003564)plasma insulin level (CMO:0000342)2150540301202447032Rat
12879845Cm89Cardiac mass QTL 890.008heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)2152413072175950118Rat
12879846Cm90Cardiac mass QTL 900.011heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)2152413072175950118Rat
12879847Am4Aortic mass QTL 40.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)2152413072175950118Rat
11565180Kidm56Kidney mass QTL 560.003kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2152413072175950118Rat
11565181Bw176Body weight QTL 1760.002body mass (VT:0001259)body weight (CMO:0000012)2152413072175950118Rat
2301415Cm67Cardiac mass QTL 670.003heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)2152413072175950118Rat
12879836Kidm61Kidney mass QTL 610.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2152413072185122374Rat
12879837Am2Aortic mass QTL 20.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)2152413072185122374Rat
12879838Cm86Cardiac mass QTL 860.002heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)2152413072185122374Rat
12879839Cm85Cardiac mass QTL 850.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)2152413072185122374Rat
12879840Bw179Body weight QTL 1790.005body mass (VT:0001259)body weight (CMO:0000012)2152413072185122374Rat
1359032Hrtrt18Heart rate QTL 18heart pumping trait (VT:2000009)heart rate (CMO:0000002)2157142078192625452Rat
1358900Bw48Body weight QTL 484.88body mass (VT:0001259)body weight (CMO:0000012)2157142078211086598Rat
8662843Vetf9Vascular elastic tissue fragility QTL 92.05thoracic aorta molecular composition trait (VT:0010568)aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)2157142078226277316Rat
1302793Bw16Body weight QTL 1650.0001body mass (VT:0001259)body weight (CMO:0000012)2157142209202446871Rat
7488925Bp364Blood pressure QTL 3640.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2160564068205564068Rat
1358356Srcrt1Stress Responsive Cort QTL13.66blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)2161699179222436696Rat
7488927Bp365Blood pressure QTL 3650.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2162765032207765032Rat
2306901Bp337Blood pressure QTL 3370.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2164073756227146641Rat
1598838Bp290Blood pressure QTL 2901.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2166539266211539266Rat
1549833Bp257Blood pressure QTL 2570.003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2168354880185122374Rat
1331734Bp204Blood pressure QTL 2043.61192arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2168358098223265385Rat
2307174Activ3Activity QTL 34.830.000058locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)2168594495213594495Rat
61469Bp16Blood pressure QTL 165.64arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)2169745596214745596Rat
70162Bp63Blood pressure QTL 635.64arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)2169745596214745596Rat
61473Bp19Blood pressure QTL 196.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2172710921175950118Rat
631522Bp74Blood pressure QTL 740.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2172710921184114403Rat
7488904Bp363Blood pressure QTL 3630.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2172982062175950118Rat

Markers in Region
D2Mco45  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22173,103,977 - 173,104,221 (+)MAPPERmRatBN7.2
Rnor_6.02187,009,630 - 187,009,873NCBIRnor6.0
Rnor_5.02206,414,549 - 206,414,792UniSTSRnor5.0
RGSC_v3.42179,704,792 - 179,705,036RGDRGSC3.4
RGSC_v3.42179,704,793 - 179,705,036UniSTSRGSC3.4
Celera2167,052,956 - 167,053,199UniSTS
Cytogenetic Map2q34UniSTS
BI289089  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22173,194,055 - 173,194,162 (+)MAPPERmRatBN7.2
Rnor_6.02187,100,617 - 187,100,723NCBIRnor6.0
Rnor_5.02206,505,525 - 206,505,631UniSTSRnor5.0
RGSC_v3.42179,795,831 - 179,795,937UniSTSRGSC3.4
Celera2167,143,614 - 167,143,720UniSTS
RH 3.4 Map21130.4UniSTS
Cytogenetic Map2q34UniSTS


Genetic Models
This gene Arhgef11 is modified in the following models/strains:


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 33 29 19 8 19 1 2 74 35 40 11 1
Low 10 28 22 11 22 7 9 1 7
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_023982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006232759 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006232766 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761217 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761220 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761222 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761223 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761224 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761225 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591126 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103179 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103180 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103181 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103182 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103183 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103184 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103186 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103188 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103189 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282598 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282600 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282602 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282603 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282604 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282605 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282606 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC119000 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF225961 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473976 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000020717   ⟹   ENSRNOP00000020717
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2173,138,916 - 173,193,887 (+)Ensembl
Rnor_6.0 Ensembl2186,980,992 - 187,101,571 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000091336   ⟹   ENSRNOP00000070996
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2173,138,916 - 173,193,887 (+)Ensembl
Rnor_6.0 Ensembl2186,980,793 - 187,101,768 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000106820   ⟹   ENSRNOP00000086384
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2173,074,368 - 173,196,010 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000114540   ⟹   ENSRNOP00000086176
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2173,074,402 - 173,196,010 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000116714   ⟹   ENSRNOP00000088812
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2173,074,389 - 173,196,010 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000119098   ⟹   ENSRNOP00000083614
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2173,074,373 - 173,196,010 (+)Ensembl
RefSeq Acc Id: NM_023982   ⟹   NP_076472
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,290 - 175,493,852 (+)NCBI
mRatBN7.22173,074,395 - 173,195,962 (+)NCBI
Rnor_6.02186,980,992 - 187,101,571 (+)NCBI
Rnor_5.02206,384,799 - 206,507,431 (+)NCBI
RGSC_v3.42179,676,236 - 179,796,785 (+)RGD
Celera2167,024,592 - 167,144,568 (+)RGD
Sequence:
RefSeq Acc Id: XM_006232759   ⟹   XP_006232821
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
mRatBN7.22173,074,385 - 173,195,962 (+)NCBI
Rnor_6.02186,979,850 - 187,102,523 (+)NCBI
Rnor_5.02206,384,799 - 206,507,431 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006232766   ⟹   XP_006232828
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
mRatBN7.22173,074,385 - 173,195,962 (+)NCBI
Rnor_6.02186,979,850 - 187,102,523 (+)NCBI
Rnor_5.02206,384,799 - 206,507,431 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017591126   ⟹   XP_017446615
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
mRatBN7.22173,074,385 - 173,195,962 (+)NCBI
Rnor_6.02186,979,850 - 187,102,523 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039103176   ⟹   XP_038959104
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
mRatBN7.22173,074,385 - 173,195,962 (+)NCBI
RefSeq Acc Id: XM_039103177   ⟹   XP_038959105
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
mRatBN7.22173,074,383 - 173,195,962 (+)NCBI
RefSeq Acc Id: XM_039103178   ⟹   XP_038959106
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
mRatBN7.22173,074,383 - 173,195,962 (+)NCBI
RefSeq Acc Id: XM_039103179   ⟹   XP_038959107
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
mRatBN7.22173,074,383 - 173,195,962 (+)NCBI
RefSeq Acc Id: XM_039103180   ⟹   XP_038959108
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
mRatBN7.22173,074,385 - 173,195,962 (+)NCBI
RefSeq Acc Id: XM_039103181   ⟹   XP_038959109
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
mRatBN7.22173,074,385 - 173,195,962 (+)NCBI
RefSeq Acc Id: XM_039103182   ⟹   XP_038959110
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
mRatBN7.22173,074,383 - 173,195,962 (+)NCBI
RefSeq Acc Id: XM_039103183   ⟹   XP_038959111
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
mRatBN7.22173,074,383 - 173,195,962 (+)NCBI
RefSeq Acc Id: XM_039103184   ⟹   XP_038959112
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
mRatBN7.22173,074,385 - 173,195,962 (+)NCBI
RefSeq Acc Id: XM_039103185   ⟹   XP_038959113
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
mRatBN7.22173,074,384 - 173,195,962 (+)NCBI
RefSeq Acc Id: XM_039103186   ⟹   XP_038959114
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
mRatBN7.22173,074,383 - 173,195,962 (+)NCBI
RefSeq Acc Id: XM_039103187   ⟹   XP_038959115
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
mRatBN7.22173,074,383 - 173,195,962 (+)NCBI
RefSeq Acc Id: XM_039103188   ⟹   XP_038959116
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
mRatBN7.22173,074,385 - 173,195,962 (+)NCBI
RefSeq Acc Id: XM_039103189   ⟹   XP_038959117
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
mRatBN7.22173,074,385 - 173,195,962 (+)NCBI
RefSeq Acc Id: XM_063282598   ⟹   XP_063138668
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
RefSeq Acc Id: XM_063282599   ⟹   XP_063138669
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
RefSeq Acc Id: XM_063282600   ⟹   XP_063138670
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
RefSeq Acc Id: XM_063282601   ⟹   XP_063138671
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
RefSeq Acc Id: XM_063282602   ⟹   XP_063138672
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
RefSeq Acc Id: XM_063282603   ⟹   XP_063138673
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
RefSeq Acc Id: XM_063282604   ⟹   XP_063138674
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
RefSeq Acc Id: XM_063282605   ⟹   XP_063138675
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
RefSeq Acc Id: XM_063282606   ⟹   XP_063138676
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,488,295 (+)NCBI
Protein Sequences
Protein RefSeqs NP_076472 (Get FASTA)   NCBI Sequence Viewer  
  XP_006232821 (Get FASTA)   NCBI Sequence Viewer  
  XP_006232828 (Get FASTA)   NCBI Sequence Viewer  
  XP_017446615 (Get FASTA)   NCBI Sequence Viewer  
  XP_038959104 (Get FASTA)   NCBI Sequence Viewer  
  XP_038959105 (Get FASTA)   NCBI Sequence Viewer  
  XP_038959106 (Get FASTA)   NCBI Sequence Viewer  
  XP_038959107 (Get FASTA)   NCBI Sequence Viewer  
  XP_038959108 (Get FASTA)   NCBI Sequence Viewer  
  XP_038959109 (Get FASTA)   NCBI Sequence Viewer  
  XP_038959110 (Get FASTA)   NCBI Sequence Viewer  
  XP_038959111 (Get FASTA)   NCBI Sequence Viewer  
  XP_038959112 (Get FASTA)   NCBI Sequence Viewer  
  XP_038959113 (Get FASTA)   NCBI Sequence Viewer  
  XP_038959114 (Get FASTA)   NCBI Sequence Viewer  
  XP_038959115 (Get FASTA)   NCBI Sequence Viewer  
  XP_038959116 (Get FASTA)   NCBI Sequence Viewer  
  XP_038959117 (Get FASTA)   NCBI Sequence Viewer  
  XP_063138668 (Get FASTA)   NCBI Sequence Viewer  
  XP_063138669 (Get FASTA)   NCBI Sequence Viewer  
  XP_063138670 (Get FASTA)   NCBI Sequence Viewer  
  XP_063138671 (Get FASTA)   NCBI Sequence Viewer  
  XP_063138672 (Get FASTA)   NCBI Sequence Viewer  
  XP_063138673 (Get FASTA)   NCBI Sequence Viewer  
  XP_063138674 (Get FASTA)   NCBI Sequence Viewer  
  XP_063138675 (Get FASTA)   NCBI Sequence Viewer  
  XP_063138676 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAG28597 (Get FASTA)   NCBI Sequence Viewer  
  EDM00775 (Get FASTA)   NCBI Sequence Viewer  
  EDM00776 (Get FASTA)   NCBI Sequence Viewer  
  EDM00777 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000020717
  ENSRNOP00000020717.8
  ENSRNOP00000070996
  ENSRNOP00000070996.2
  ENSRNOP00000083614.1
  ENSRNOP00000086176
  ENSRNOP00000086176.1
  ENSRNOP00000086384.1
  ENSRNOP00000088812.1
GenBank Protein Q9ES67 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_076472   ⟸   NM_023982
- UniProtKB: Q9ES67 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006232821   ⟸   XM_006232759
- Peptide Label: isoform X1
- UniProtKB: A0A8I6A8L7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006232828   ⟸   XM_006232766
- Peptide Label: isoform X11
- UniProtKB: A0A8I6A5B5 (UniProtKB/TrEMBL),   A0A8I6A8L7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017446615   ⟸   XM_017591126
- Peptide Label: isoform X5
- UniProtKB: A0A8I6A8L7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000020717   ⟸   ENSRNOT00000020717
RefSeq Acc Id: ENSRNOP00000070996   ⟸   ENSRNOT00000091336
RefSeq Acc Id: XP_038959105   ⟸   XM_039103177
- Peptide Label: isoform X2
- UniProtKB: A0A8I6A8L7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038959106   ⟸   XM_039103178
- Peptide Label: isoform X4
- UniProtKB: A0A8I6A8L7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038959110   ⟸   XM_039103182
- Peptide Label: isoform X9
- UniProtKB: A0A8I6A8L7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038959114   ⟸   XM_039103186
- Peptide Label: isoform X18
- UniProtKB: Q9ES67 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038959115   ⟸   XM_039103187
- Peptide Label: isoform X19
- UniProtKB: Q9ES67 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038959107   ⟸   XM_039103179
- Peptide Label: isoform X6
- UniProtKB: A0A8I6A8L7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038959111   ⟸   XM_039103183
- Peptide Label: isoform X13
- UniProtKB: A0A8I6A8L7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038959113   ⟸   XM_039103185
- Peptide Label: isoform X16
- UniProtKB: A0A8I6AAM2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038959108   ⟸   XM_039103180
- Peptide Label: isoform X7
- UniProtKB: A0A8I6A8L7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038959104   ⟸   XM_039103176
- Peptide Label: isoform X3
- UniProtKB: A0A8I6A8L7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038959109   ⟸   XM_039103181
- Peptide Label: isoform X8
- UniProtKB: A0A8I6A8L7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038959116   ⟸   XM_039103188
- Peptide Label: isoform X20
- UniProtKB: A0A8I6A8L7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038959112   ⟸   XM_039103184
- Peptide Label: isoform X17
- UniProtKB: Q9ES67 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038959117   ⟸   XM_039103189
- Peptide Label: isoform X25
- UniProtKB: Q9ES67 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: ENSRNOP00000083614   ⟸   ENSRNOT00000119098
RefSeq Acc Id: ENSRNOP00000086384   ⟸   ENSRNOT00000106820
RefSeq Acc Id: ENSRNOP00000088812   ⟸   ENSRNOT00000116714
RefSeq Acc Id: ENSRNOP00000086176   ⟸   ENSRNOT00000114540
RefSeq Acc Id: XP_063138668   ⟸   XM_063282598
- Peptide Label: isoform X10
RefSeq Acc Id: XP_063138670   ⟸   XM_063282600
- Peptide Label: isoform X14
RefSeq Acc Id: XP_063138669   ⟸   XM_063282599
- Peptide Label: isoform X12
RefSeq Acc Id: XP_063138671   ⟸   XM_063282601
- Peptide Label: isoform X15
RefSeq Acc Id: XP_063138672   ⟸   XM_063282602
- Peptide Label: isoform X21
RefSeq Acc Id: XP_063138674   ⟸   XM_063282604
- Peptide Label: isoform X23
RefSeq Acc Id: XP_063138673   ⟸   XM_063282603
- Peptide Label: isoform X22
RefSeq Acc Id: XP_063138675   ⟸   XM_063282605
- Peptide Label: isoform X24
RefSeq Acc Id: XP_063138676   ⟸   XM_063282606
- Peptide Label: isoform X26
Protein Domains
DH   PDZ   PH   RGS   RGSL

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9ES67-F1-model_v2 AlphaFold Q9ES67 1-1527 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619705 AgrOrtholog
BioCyc Gene G2FUF-52538 BioCyc
Ensembl Genes ENSRNOG00000015026 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000020717.8 UniProtKB/TrEMBL
  ENSRNOT00000091336 ENTREZGENE
  ENSRNOT00000091336.2 UniProtKB/TrEMBL
  ENSRNOT00000106820.1 UniProtKB/TrEMBL
  ENSRNOT00000114540.1 UniProtKB/TrEMBL
  ENSRNOT00000116714.1 UniProtKB/TrEMBL
  ENSRNOT00000119098.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.167.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.900.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.30.42.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro DBL_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DH-domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GDS_CDC24_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDZ_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDZRhoGEF_RGS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH_16 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PRG_PH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RGS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RGS-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RGS_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RGS_subdomain_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:78966 UniProtKB/Swiss-Prot
NCBI Gene 78966 ENTREZGENE
PANTHER PTHR45872:SF1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 2, ISOFORM D UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH_16 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RGS-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RhoGEF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Arhgef11 PhenoGen
PROSITE DH_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DH_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RGS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000015026 RatGTEx
SMART PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RGS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RhoGEF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00233 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF48065 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF48097 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF50156 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JZC6_RAT UniProtKB/TrEMBL
  A0A8I5ZXJ6_RAT UniProtKB/TrEMBL
  A0A8I6A5B5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A8L7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AAM2 ENTREZGENE, UniProtKB/TrEMBL
  A6J612_RAT UniProtKB/TrEMBL
  A6J613_RAT UniProtKB/TrEMBL
  A6J614_RAT UniProtKB/TrEMBL
  ARHGB_RAT UniProtKB/Swiss-Prot
  F1LQS9_RAT UniProtKB/TrEMBL
  Q9ES67 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-19 Arhgef11  Rho guanine nucleotide exchange factor 11  Arhgef11  Rho guanine nucleotide exchange factor (GEF) 11  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Arhgef11  Rho guanine nucleotide exchange factor (GEF) 11  Gtrap48  RhoGEF glutamate transport modulator GTRAP48  Symbol and Name updated 1299863 APPROVED
2002-08-07 Gtrap48  RhoGEF glutamate transport modulator GTRAP48      Symbol and Name status set to provisional 70820 PROVISIONAL