Strain Report - Rat Genome Database

Send us a Message

Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

Strain: WI- Msh6m1Hubr

Symbol: WI- Msh6m1Hubr
Strain: WI- Msh6m1
Substrain: Hubr
RGD ID: 126848737
Citation ID: RRID:RGD_126848737
Ontology ID: RS:0004924
Alleles: Msh6m1Hubr
Type: mutant
Source: Hubrecht Laboratory, Centre for Biomedical Genetics, 3584 CT Utrecht, The Netherlands. Hera Biolabs, Taconic.
Origin: The Msh6 knockout mutant rat line was generated by target-selected ENU-driven mutagenesis on Crl:WI rats. The founder rat carried an ENU-induced premature stop codon in exon 4 of the Msh6 gene was bred to obtain homozygous animals.
Last Known Status: Unknown
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.266,562,631 - 6,579,995RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0611,644,565 - 11,662,389RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0621,616,672 - 21,634,338RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4611,525,292 - 11,542,592RGD_MAPPER_PIPELINERGSC3.4

Disease Annotations     Click to see Annotation Detail View

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype


References - curated
# Reference Title Reference Citation
1. Lack of DNA mismatch repair protein MSH6 in the rat results in hereditary non-polyposis colorectal cancer-like tumorigenesis. van Boxtel R, etal., Carcinogenesis. 2008 Apr 15;.


Additional Information