Ccr2 (C-C motif chemokine receptor 2) - Rat Genome Database

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Gene: Ccr2 (C-C motif chemokine receptor 2) Rattus norvegicus
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Symbol: Ccr2
Name: C-C motif chemokine receptor 2
RGD ID: 620876
Description: ENCODES a protein that exhibits identical protein binding; C-C chemokine receptor activity (ortholog); CCR2 chemokine receptor binding (ortholog); INVOLVED IN blood vessel remodeling; cellular calcium ion homeostasis; chemokine-mediated signaling pathway; PARTICIPATES IN chemokine mediated signaling pathway; cytokine mediated signaling pathway; ASSOCIATED WITH demyelinating disease; Experimental Arthritis; Experimental Autoimmune Encephalomyelitis; FOUND IN cytosol; dendrite; neuronal cell body; INTERACTS WITH (+)-pilocarpine; 17alpha-ethynylestradiol; acrylamide
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: C-C chemokine receptor type 2; C-C CKR-2; CC-CKR-2; CCR-2; chemokine (C-C motif) receptor 2; chemokine receptor CCR2; chemokine receptor CCR2 gene
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Alliance Genes
More Info more info ...
Allele / Splice: Ccr2m1Mcwi   Ccr2m2Mcwi  
Genetic Models: FHH-Ccr2m1Mcwi BN-Ccr2m2Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.28123,734,465 - 123,742,483 (+)NCBI
RGSC_v3.48128,892,784 - 128,893,905 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.18128,912,520 - 128,913,642 (+)NCBI
Celera8122,833,545 - 122,834,666 (+)NCBICelera
Cytogenetic Map8q32NCBI


Disease Annotations     Click to see Annotation Detail View
age related macular degeneration  (ISS)
aggressive periodontitis  (ISO)
Alcoholic Fatty Liver  (ISO)
allergic bronchopulmonary aspergillosis  (ISO)
allergic contact dermatitis  (ISO)
allergic disease  (ISO)
Alveolar Bone Loss  (ISO)
amyotrophic lateral sclerosis  (ISO)
Animal Toxoplasmosis  (ISO)
anxiety disorder  (ISO)
asthma  (ISO)
atopic dermatitis  (ISO)
bacterial pneumonia  (ISO)
Bronchial Hyperreactivity  (ISO)
bronchiolitis obliterans  (ISO)
Chemical and Drug Induced Liver Injury  (ISO)
Choroidal Neovascularization  (ISO)
Chronic Periodontitis  (ISO)
congestive heart failure  (ISO)
corneal neovascularization  (ISO)
coronary artery disease  (ISO)
Coronavirus infectious disease  (ISS)
COVID-19  (ISO)
cutaneous leishmaniasis  (ISO)
demyelinating disease  (IEP)
dermatomyositis  (ISO)
Diabetic Nephropathies  (ISO)
dry eye syndrome  (ISO)
Experimental Arthritis  (IEP)
Experimental Autoimmune Encephalomyelitis  (IEP)
Experimental Autoimmune Uveitis  (ISO)
Experimental Autoimmune Uveoretinitis  (ISO)
fungal infectious disease  (ISO)
Geographic Atrophy  (ISO)
Hearing Loss, Noise-Induced  (ISO)
Herpes Simplex Encephalitis  (ISO)
Herpesviridae Infections  (ISO)
human immunodeficiency virus infectious disease  (ISO)
Hyperalgesia  (IEP,IMP,ISO)
Hypoxia-Ischemia, Brain  (IEP)
ileitis  (ISO)
inclusion body myositis  (ISO)
intermediate uveitis  (ISO)
interstitial lung disease  (ISO)
Intervertebral Disc Disease  (IEP)
Intimal Hyperplasia  (ISO)
Kawasaki disease  (ISO)
Knee Osteoarthritis  (ISO)
Kuhnt-Junius degeneration  (ISO)
leishmaniasis  (ISO)
limited scleroderma  (ISO)
lipoatrophic diabetes mellitus  (ISO)
liver disease  (ISO)
Liver Reperfusion Injury  (ISO)
lung disease  (ISO)
macular degeneration  (ISO)
Mouth Neoplasms  (ISO)
myeloid sarcoma  (ISO)
myocardial infarction  (ISO)
Myocardial Reperfusion Injury  (ISO)
Nasal Polyps  (ISO)
non-alcoholic fatty liver disease  (ISO)
oral squamous cell carcinoma  (ISO)
Pain  (IMP,ISO)
Perennial Allergic Rhinitis  (ISO)
Peri-Implantitis  (ISO)
Periapical Diseases  (ISO)
periapical granuloma  (ISO)
periapical periodontitis  (IEP)
Periodontal Cyst  (ISO)
pleural tuberculosis  (ISO)
pneumonia  (ISO)
polymyositis  (ISO)
posterior uveitis  (ISO)
prediabetes syndrome  (ISO)
psoriasis  (ISO)
psoriatic arthritis  (ISO)
pulmonary fibrosis  (ISO)
pulmonary tuberculosis  (ISO)
retinal degeneration  (ISO)
retinitis  (ISO)
rhinitis  (ISO)
sarcoidosis  (ISO)
sciatic neuropathy  (ISO)
sialadenitis  (ISO)
Spinal Cord Injuries  (IEP)
status epilepticus  (ISO)
systemic scleroderma  (ISO)
Thoracic Injuries  (IEP)
Transplant Rejection  (ISO)
type 1 diabetes mellitus  (ISO)
type 2 diabetes mellitus  (ISO)
urticaria  (ISO)
vasculitis  (ISO)
visceral leishmaniasis  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(+)-pilocarpine  (EXP,ISO)
(R)-mevalonic acid  (ISO)
1,3-benzothiazole-2-thiol  (ISO)
1,4-phenylenediamine  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
1-fluoro-2,4-dinitrobenzene  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (ISO)
1-O-palmitoyl-2-O-(5-oxovaleryl)-sn-glycero-3-phosphocholine  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2,4-dinitrobenzenesulfonic acid  (ISO)
2-acetyl-1-alkyl-sn-glycero-3-phosphocholine  (ISO)
2-butoxyethanol  (ISO)
3-chlorophenol  (ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
9-cis-retinoic acid  (ISO)
acetaldehyde  (ISO)
acrylamide  (EXP)
aflatoxin B1  (ISO)
aflatoxin B2  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
ammonium hexachloroplatinate  (ISO)
amphetamine  (EXP)
amphotericin B  (EXP)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
asbestos  (ISO)
asperentin  (ISO)
barium sulfate  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (EXP)
benzylpenicillin  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP)
bleomycin A2  (ISO)
buta-1,3-diene  (ISO)
carbon nanotube  (ISO)
celecoxib  (ISO)
ceric oxide  (EXP)
chenodeoxycholic acid  (ISO)
chloroprene  (ISO)
choline  (ISO)
cis-caffeic acid  (ISO)
cisplatin  (ISO)
cocaine  (EXP,ISO)
crocidolite asbestos  (ISO)
curcumin  (ISO)
cyclosporin A  (ISO)
deoxycholic acid  (ISO)
deoxynivalenol  (ISO)
dextran sulfate  (ISO)
dibenz[a,h]anthracene  (EXP)
dibenzo[a,l]pyrene  (EXP)
diethylstilbestrol  (ISO)
disulfiram  (ISO)
doxorubicin  (EXP)
erythromycin A  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
eugenol  (ISO)
flumequine  (ISO)
folic acid  (ISO)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
isoniazide  (EXP)
L-methionine  (ISO)
lead diacetate  (EXP,ISO)
linuron  (ISO)
losartan  (EXP)
LY294002  (ISO)
mechlorethamine  (EXP)
MeIQx  (ISO)
mercury atom  (ISO)
mercury dichloride  (EXP)
mercury(0)  (ISO)
metformin  (ISO)
methamphetamine  (ISO)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
mycophenolic acid  (ISO)
mycotoxin  (ISO)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (ISO)
nefazodone  (ISO)
neoechinulin A  (ISO)
nickel atom  (ISO)
nickel sulfate  (ISO)
olaparib  (ISO)
oxaliplatin  (EXP)
ozone  (EXP,ISO)
paracetamol  (EXP,ISO)
paricalcitol  (ISO)
PCB138  (ISO)
perindopril  (ISO)
picrotoxin  (EXP)
piperidines  (ISO)
proanthocyanidin  (ISO)
protein kinase inhibitor  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
SB 203580  (ISO)
serpentine asbestos  (ISO)
silicon dioxide  (EXP,ISO)
simvastatin  (EXP,ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium chlorate  (ISO)
sodium fluoride  (EXP)
sterigmatocystin  (ISO)
streptozocin  (ISO)
sulforaphane  (ISO)
tacrolimus hydrate  (ISO)
tamoxifen  (ISO)
telmisartan  (EXP)
tetrachloromethane  (ISO)
thiram  (ISO)
titanium dioxide  (ISO)
toluene 2,4-diisocyanate  (ISO)
topotecan  (EXP)
trans-caffeic acid  (ISO)
trichostatin A  (ISO)
tungsten  (ISO)
valproic acid  (EXP)
vinclozolin  (EXP)
zinc sulfate  (ISO)
ziram  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
blood vessel remodeling  (IEP)
calcium-mediated signaling  (IBA)
cell chemotaxis  (IBA)
cellular calcium ion homeostasis  (IDA)
cellular defense response  (ISO)
cellular homeostasis  (ISO,ISS)
chemokine-mediated signaling pathway  (IMP)
cytokine-mediated signaling pathway  (IMP,ISO)
G protein-coupled receptor signaling pathway  (IMP)
hemopoiesis  (ISO)
homeostasis of number of cells within a tissue  (ISO)
humoral immune response  (ISO)
immune response  (IBA,ISO)
inflammatory response  (IBA,IDA,ISO)
inflammatory response to antigenic stimulus  (IEP)
inflammatory response to wounding  (ISO,ISS)
leukocyte adhesion to vascular endothelial cell  (ISO)
macrophage migration  (ISO,ISS)
monocyte chemotaxis  (ISO)
monocyte extravasation  (ISO,ISS)
negative regulation of angiogenesis  (ISO,ISS)
negative regulation of eosinophil degranulation  (ISO,ISS)
negative regulation of type 2 immune response  (ISO,ISS)
neutrophil clearance  (ISO)
positive regulation of alpha-beta T cell proliferation  (ISO,ISS)
positive regulation of astrocyte chemotaxis  (ISO,ISS)
positive regulation of CD8-positive, alpha-beta T cell extravasation  (ISO,ISS)
positive regulation of cold-induced thermogenesis  (ISO,ISS)
positive regulation of cytosolic calcium ion concentration  (IBA)
positive regulation of hematopoietic stem cell migration  (ISO,ISS)
positive regulation of immune complex clearance by monocytes and macrophages  (ISO,ISS)
positive regulation of inflammatory response  (ISO,ISS)
positive regulation of interferon-gamma production  (ISO,ISS)
positive regulation of interleukin-2 production  (ISO,ISS)
positive regulation of leukocyte tethering or rolling  (ISO)
positive regulation of monocyte chemotaxis  (ISO,ISS)
positive regulation of monocyte extravasation  (ISO,ISS)
positive regulation of NMDA glutamate receptor activity  (IGI)
positive regulation of p38MAPK cascade  (IDA)
positive regulation of synaptic transmission, glutamatergic  (ISO,ISS)
positive regulation of T cell activation  (ISO,ISS)
positive regulation of T cell chemotaxis  (ISO,ISS)
positive regulation of T-helper 1 type immune response  (ISO,ISS)
positive regulation of thymocyte migration  (ISO,ISS)
positive regulation of tumor necrosis factor production  (IMP,ISO,ISS)
regulation of cell migration  (ISO)
regulation of inflammatory response  (ISO,ISS)
regulation of T cell cytokine production  (ISO,ISS)
regulation of T cell differentiation  (ISO,ISS)
regulation of vascular endothelial growth factor production  (ISO,ISS)
response to hyperoxia  (IEP)
response to hypoxia  (IEP)
sensory perception of pain  (ISO,ISS)
T-helper 17 cell chemotaxis  (ISO,ISS)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
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107. Zhu XL, etal., Chin J Dent Res. 2010;13(2):109-14.
Additional References at PubMed
PMID:8631787   PMID:8662823   PMID:8996246   PMID:9342361   PMID:9366570   PMID:10657654   PMID:10854218   PMID:10993920   PMID:12271471   PMID:12808141   PMID:14566334   PMID:15995708  
PMID:16148108   PMID:17484785   PMID:18421085   PMID:18586982   PMID:18587271   PMID:18832716   PMID:20034406   PMID:20234092   PMID:21143971   PMID:22466130   PMID:23049171   PMID:23288990  
PMID:23594826   PMID:23610400   PMID:23913046   PMID:24806994   PMID:26062549   PMID:28507030   PMID:29142497   PMID:29359616   PMID:29632244   PMID:29930553   PMID:29993042   PMID:30201767  
PMID:31034839   PMID:31805255   PMID:32164451  


Genomics

Comparative Map Data
Ccr2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.28123,734,465 - 123,742,483 (+)NCBI
RGSC_v3.48128,892,784 - 128,893,905 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.18128,912,520 - 128,913,642 (+)NCBI
Celera8122,833,545 - 122,834,666 (+)NCBICelera
Cytogenetic Map8q32NCBI
CCR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl346,353,744 - 46,360,940 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl346,353,734 - 46,360,928 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl346,353,864 - 46,360,940 (+)EnsemblGRCh38hg38GRCh38
GRCh38346,354,111 - 46,360,940 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37346,395,602 - 46,402,431 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36346,370,364 - 46,377,432 (+)NCBINCBI36hg18NCBI36
Celera346,332,557 - 46,339,734 (+)NCBI
Cytogenetic Map3p21.31NCBI
HuRef346,438,874 - 46,446,051 (+)NCBIHuRef
CHM1_1346,345,233 - 46,352,410 (+)NCBICHM1_1
Ccr2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399123,901,954 - 123,913,594 (+)NCBIGRCm39mm39
GRCm39 Ensembl9123,901,987 - 123,913,594 (+)Ensembl
GRCm389124,101,918 - 124,109,140 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9124,101,950 - 124,113,557 (+)EnsemblGRCm38mm10GRCm38
MGSCv379124,016,922 - 124,023,879 (+)NCBIGRCm37mm9NCBIm37
MGSCv369123,950,982 - 123,957,349 (+)NCBImm8
Celera9124,890,502 - 124,897,441 (-)NCBICelera
Cytogenetic Map9F4NCBI
cM Map975.05NCBI
Ccr2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542025,641,184 - 25,664,413 (-)NCBIChiLan1.0ChiLan1.0
CCR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1347,361,118 - 47,368,312 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl347,361,124 - 47,368,312 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0346,255,725 - 46,263,285 (+)NCBIMhudiblu_PPA_v0panPan3
CCR2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12042,305,344 - 42,313,258 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2042,307,580 - 42,308,698 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2042,220,658 - 42,229,191 (-)NCBI
ROS_Cfam_1.02042,787,203 - 42,795,751 (-)NCBI
UMICH_Zoey_3.12042,028,417 - 42,036,962 (-)NCBI
UNSW_CanFamBas_1.02042,429,835 - 42,438,385 (-)NCBI
UU_Cfam_GSD_1.02042,710,738 - 42,719,282 (-)NCBI
CCR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1329,251,959 - 29,376,346 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11329,368,735 - 29,374,564 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21332,532,565 - 32,538,394 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CCR2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1227,795,192 - 7,801,242 (+)NCBI
ChlSab1.1 Ensembl227,798,646 - 7,799,728 (+)Ensembl
Vero_WHO_p1.0NW_023666041159,351,063 - 159,358,108 (-)NCBI

Position Markers
PMC164693P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
RGSC_v3.48128,893,811 - 128,893,893UniSTSRGSC3.4
Celera8122,834,572 - 122,834,654UniSTS
Cytogenetic Map8q32UniSTS


Genetic Models
This gene Ccr2 is modified in the following models/strains

Expression


Sequence


Reference Sequences
RefSeq Acc Id: NM_021866   ⟹   NP_068638
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28123,738,248 - 123,739,369 (+)NCBI
RGSC_v3.48128,892,784 - 128,893,905 (+)RGD
Celera8122,833,545 - 122,834,666 (+)RGD
Sequence:
RefSeq Acc Id: XM_039082059   ⟹   XP_038937987
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28123,735,394 - 123,741,686 (+)NCBI
RefSeq Acc Id: XM_039082060   ⟹   XP_038937988
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28123,734,470 - 123,741,686 (+)NCBI
RefSeq Acc Id: XM_039082061   ⟹   XP_038937989
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28123,735,404 - 123,741,686 (+)NCBI
RefSeq Acc Id: XM_039082062   ⟹   XP_038937990
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28123,734,465 - 123,741,686 (+)NCBI
RefSeq Acc Id: XM_039082063   ⟹   XP_038937991
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28123,734,465 - 123,741,686 (+)NCBI
RefSeq Acc Id: XM_039082064   ⟹   XP_038937992
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.28123,735,350 - 123,742,483 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_068638   ⟸   NM_021866
- UniProtKB: O55193 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_038937990   ⟸   XM_039082062
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038937991   ⟸   XM_039082063
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038937988   ⟸   XM_039082060
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038937992   ⟸   XM_039082064
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038937987   ⟸   XM_039082059
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038937989   ⟸   XM_039082061
- Peptide Label: isoform X2


Additional Information

Database Acc Id Source(s)
InterPro Chemokine_CCR2 UniProtKB/Swiss-Prot
  Chemokine_rcpt UniProtKB/Swiss-Prot
  GPCR_Rhodpsn UniProtKB/Swiss-Prot
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot
KEGG Report rno:60463 UniProtKB/Swiss-Prot
NCBI Gene 60463 ENTREZGENE
Pfam 7tm_1 UniProtKB/Swiss-Prot
PhenoGen Ccr2 PhenoGen
PRINTS CCCHEMOKINER UniProtKB/Swiss-Prot
  CHEMOKINER2 UniProtKB/Swiss-Prot
  GPCRRHODOPSN UniProtKB/Swiss-Prot
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot
SMART 7TM_GPCR_Srsx UniProtKB/Swiss-Prot
UniProt CCR2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-22 Ccr2  C-C motif chemokine receptor 2  Ccr2  chemokine (C-C motif) receptor 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Ccr2  chemokine (C-C motif) receptor 2    chemokine receptor CCR2 gene  Name updated 1299863 APPROVED
2002-08-07 Ccr2  chemokine receptor CCR2 gene      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in spleen, lung, kidney, thymus, and macrophages 632391
gene_regulation increased after induction of experimental allergic encephalomyelitis (EAE) 632391