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Pathways
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Gene: Mas1 (MAS1 proto-oncogene, G protein-coupled receptor) Rattus norvegicus
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Symbol: Mas1
Name: MAS1 proto-oncogene, G protein-coupled receptor
Description: Predicted to have angiotensin receptor activity and peptide binding activity. Involved in several processes, including hippocampus development; male gonad development; and positive regulation of cellular biosynthetic process. Localizes to the cell surface. Used to study glaucoma and hypertension. Biomarker of congestive heart failure; dilated cardiomyopathy; and primary biliary cirrhosis. Orthologous to human MAS1 (MAS1 proto-oncogene, G protein-coupled receptor); PARTICIPATES IN angiotensin (1-7) signaling pathway; renin-angiotensin cascade pathway; INTERACTS WITH 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: angiotensin-(1-7) receptor; c-mas; MAS proto-oncogene; Mas-related G protein-coupled receptor a; MAS1 oncogene; Mgra; proto-oncogene Mas
Orthologs:
Homo sapiens (human) : MAS1 (MAS1 proto-oncogene, G protein-coupled receptor)  HGNC  Alliance
Mus musculus (house mouse) : Mas1 (MAS1 oncogene)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mas1 (MAS1 proto-oncogene, G protein-coupled receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : MAS1 (MAS1 proto-oncogene, G protein-coupled receptor)
Canis lupus familiaris (dog) : MAS1 (MAS1 proto-oncogene, G protein-coupled receptor)
Sus scrofa (pig) : MAS1 (MAS1 proto-oncogene, G protein-coupled receptor)
more info ...
Allele / Splice: Mas1em1Mcwi  
Genetic Models: SS-Mas1em1Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0148,076,761 - 48,108,218 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0151,644,462 - 51,675,365 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4142,154,786 - 42,185,750 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1142,157,730 - 42,188,693 (+)NCBI
Celera143,680,754 - 43,711,122 (+)NCBICelera
Cytogenetic Map1q11NCBI
RH 3.4 Map1544.2RGD
JBrowse: View Region in Genome Browser (JBrowse)
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Genomics

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QTLs in Region (Rnor_6.0)
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Sequence

Nucleotide Sequences
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Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
  
More on Mas1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3049
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-10-01
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.