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Gene: Mas1 (MAS1 proto-oncogene, G protein-coupled receptor) Rattus norvegicus
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Symbol: Mas1
Name: MAS1 proto-oncogene, G protein-coupled receptor
Description: Predicted to have angiotensin receptor activity and peptide binding activity. Involved in several processes, including hippocampus development; male gonad development; and positive regulation of cellular biosynthetic process. Localizes to the cell surface. Used to study glaucoma and hypertension. Biomarker of congestive heart failure; dilated cardiomyopathy; and primary biliary cirrhosis. Orthologous to human MAS1 (MAS1 proto-oncogene, G protein-coupled receptor); PARTICIPATES IN angiotensin (1-7) signaling pathway; renin-angiotensin cascade pathway; INTERACTS WITH 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: angiotensin-(1-7) receptor; c-mas; MAS proto-oncogene; Mas-related G protein-coupled receptor a; MAS1 oncogene; Mgra; proto-oncogene Mas
Orthologs:
Allele / Splice: Mas1em1Mcwi  
Genetic Models: SS-Mas1em1Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0148,076,761 - 48,108,218 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0151,644,462 - 51,675,365 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4142,154,786 - 42,185,750 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1142,157,730 - 42,188,693 (+)NCBI
Celera143,680,754 - 43,711,122 (+)NCBICelera
Cytogenetic Map1q11NCBI
RH 3.4 Map1544.2RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Protein Structures
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Mas1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3049
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-10-01
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.