Ifnar1 (interferon alpha and beta receptor subunit 1) - Rat Genome Database

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Gene: Ifnar1 (interferon alpha and beta receptor subunit 1) Rattus norvegicus
Analyze
Symbol: Ifnar1
Name: interferon alpha and beta receptor subunit 1
RGD ID: 1305399
Description: Predicted to enable type I interferon binding activity and type I interferon receptor activity. Involved in cytokine-mediated signaling pathway. Predicted to be integral component of plasma membrane. Human ortholog(s) of this gene implicated in hepatitis C. Orthologous to human IFNAR1 (interferon alpha and beta receptor subunit 1); PARTICIPATES IN type I interferon signaling pathway; cytokine mediated signaling pathway; hepatitis C pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; finasteride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: interferon (alpha and beta) receptor 1; interferon (alpha, beta and omega) receptor 1; interferon alpha/beta receptor 1; LOC288264
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: Ifnar1em1   Ifnar1em2  
Genetic Models: LEW.1WR1-Ifnar1em2 LEW.1WR1-Ifnar1em1
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21130,725,774 - 30,752,227 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1130,725,790 - 30,749,979 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1139,420,142 - 39,442,802 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01132,091,572 - 32,114,232 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01131,257,245 - 31,279,947 (+)NCBIRnor_WKY
Rnor_6.01131,640,407 - 31,666,839 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1131,640,407 - 31,664,061 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01135,248,575 - 35,272,235 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41131,454,789 - 31,478,449 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11131,494,121 - 31,518,864 (+)NCBI
Celera1130,393,241 - 30,416,960 (+)NCBICelera
Cytogenetic Map11q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. IFN-alpha/beta signaling is required for polarization of cytokine responses toward a protective type 1 pattern during experimental cryptococcosis. Biondo C, etal., J Immunol. 2008 Jul 1;181(1):566-73.
2. Mechanism of HCV's resistance to IFN-alpha in cell culture involves expression of functional IFN-alpha receptor 1. Datta S, etal., Virol J. 2011 Jul 14;8(1):351.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. IRF9 Prevents CD8+ T Cell Exhaustion in an Extrinsic Manner during Acute Lymphocytic Choriomeningitis Virus Infection. Huber M, etal., J Virol. 2017 Oct 27;91(22). pii: JVI.01219-17. doi: 10.1128/JVI.01219-17. Print 2017 Nov 15.
6. Regional and temporal expression patterns of interleukin-10, interleukin-10 receptor and adhesion molecules in the rat spinal cord during chronic relapsing EAE. Ledeboer A, etal., J Neuroimmunol. 2003 Mar;136(1-2):94-103.
7. Inflammatory monocytes require type I interferon receptor signaling to activate NK cells via IL-18 during a mucosal viral infection. Lee AJ, etal., J Exp Med. 2017 Apr 3;214(4):1153-1167. doi: 10.1084/jem.20160880. Epub 2017 Mar 6.
8. IRF7-dependent type I interferon production induces lethal immune-mediated disease in STAT1 knockout mice infected with lymphocytic choriomeningitis virus. Li W, etal., J Virol. 2014 Jul;88(13):7578-88. doi: 10.1128/JVI.03117-13. Epub 2014 Apr 23.
9. Staphylococcus aureus activates type I IFN signaling in mice and humans through the Xr repeated sequences of protein A. Martin FJ, etal., J Clin Invest. 2009 Jul;119(7):1931-9.
10. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
11. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
12. A Critical Role for the Type I Interferon Receptor in Virus-Induced Autoimmune Diabetes in Rats. Qaisar N, etal., Diabetes. 2017 Jan;66(1):145-157. doi: 10.2337/db16-0462. Epub 2016 Oct 7.
13. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
15. Comprehensive gene review and curation RGD comprehensive gene curation
16. Type I interferon signaling regulates Ly6C(hi) monocytes and neutrophils during acute viral pneumonia in mice. Seo SU, etal., PLoS Pathog. 2011 Feb;7(2):e1001304. Epub 2011 Feb 24.
17. Type I IFNs mediate development of postinfluenza bacterial pneumonia in mice. Shahangian A, etal., J Clin Invest. 2009 Jul;119(7):1910-20.
Additional References at PubMed
PMID:7665574   PMID:14532120   PMID:15800576   PMID:16139798   PMID:17164250   PMID:17277142   PMID:21606371   PMID:23872679   PMID:23997220   PMID:24598055   PMID:27129230  


Genomics

Comparative Map Data
Ifnar1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21130,725,774 - 30,752,227 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1130,725,790 - 30,749,979 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1139,420,142 - 39,442,802 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01132,091,572 - 32,114,232 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01131,257,245 - 31,279,947 (+)NCBIRnor_WKY
Rnor_6.01131,640,407 - 31,666,839 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1131,640,407 - 31,664,061 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01135,248,575 - 35,272,235 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41131,454,789 - 31,478,449 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11131,494,121 - 31,518,864 (+)NCBI
Celera1130,393,241 - 30,416,960 (+)NCBICelera
Cytogenetic Map11q11NCBI
IFNAR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382133,324,395 - 33,359,864 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl2133,324,387 - 33,359,864 (+)EnsemblGRCh38hg38GRCh38
GRCh372134,696,700 - 34,732,170 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362133,619,084 - 33,653,999 (+)NCBINCBI36Build 36hg18NCBI36
Build 342133,619,083 - 33,653,996NCBI
Celera2119,887,300 - 19,922,214 (+)NCBICelera
Cytogenetic Map21q22.11ENTREZGENE
HuRef2120,166,044 - 20,200,958 (+)NCBIHuRef
CHM1_12134,259,582 - 34,294,500 (+)NCBICHM1_1
T2T-CHM13v2.02131,696,639 - 31,732,109 (+)NCBIT2T-CHM13v2.0
Ifnar1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391691,281,016 - 91,307,411 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1691,282,126 - 91,304,329 (+)EnsemblGRCm39 Ensembl
GRCm381691,485,032 - 91,510,523 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1691,485,238 - 91,507,441 (+)EnsemblGRCm38mm10GRCm38
MGSCv371691,485,460 - 91,510,768 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361691,374,108 - 91,396,296 (+)NCBIMGSCv36mm8
Celera1692,562,831 - 92,587,086 (+)NCBICelera
Cytogenetic Map16C3.3NCBI
cM Map1652.98NCBI
Ifnar1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540732,730,953 - 32,754,651 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540732,730,973 - 32,755,404 (+)NCBIChiLan1.0ChiLan1.0
IFNAR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12133,058,410 - 33,093,824 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2133,058,396 - 33,093,824 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02119,683,496 - 19,719,034 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
IFNAR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13128,854,765 - 28,876,399 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3127,950,128 - 27,972,344 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03128,160,372 - 28,182,033 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3128,160,333 - 28,195,529 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13128,027,680 - 28,049,300 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03128,037,690 - 28,059,324 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03128,540,987 - 28,562,614 (+)NCBIUU_Cfam_GSD_1.0
Ifnar1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497128,493,890 - 28,514,014 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365008,953,809 - 8,975,261 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IFNAR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13196,925,734 - 196,952,239 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113196,925,731 - 196,951,398 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
IFNAR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1258,824,600 - 58,854,519 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl258,825,916 - 58,854,568 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660711,327,549 - 1,360,671 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ifnar1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474521,546,007 - 21,572,776 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474521,545,846 - 21,569,719 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598842Glom10Glomerulus QTL 103.4kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)11135331169Rat
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)11169446234Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)11104193166113562Rat
1641927Alcrsp10Alcohol response QTL 10alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)11843667453436674Rat
724517Uae18Urinary albumin excretion QTL 183.7urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)111647204744285911Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)112295940367959403Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)112328045668280456Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)112328045668280456Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112767241082846715Rat
1300130Rf20Renal function QTL 204.44kidney glomerulus integrity trait (VT:0010546)kidney glomerulus diameter (CMO:0001166)112952841860324829Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)112952841882566702Rat


Genetic Models
This gene Ifnar1 is modified in the following models/strains
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:625
Count of miRNA genes:294
Interacting mature miRNAs:349
Transcripts:ENSRNOT00000029985
Prediction methods:Microtar, Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 5 6 74 35 41 11 5
Low 3 5 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000029985   ⟹   ENSRNOP00000031611
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1130,726,013 - 30,749,979 (+)Ensembl
Rnor_6.0 Ensembl1131,640,407 - 31,664,061 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000091472   ⟹   ENSRNOP00000070232
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1130,725,790 - 30,749,450 (+)Ensembl
Rnor_6.0 Ensembl1131,640,407 - 31,664,061 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000102384   ⟹   ENSRNOP00000092520
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1130,726,249 - 30,749,979 (+)Ensembl
RefSeq Acc Id: NM_001105893   ⟹   NP_001099363
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21130,725,790 - 30,749,450 (+)NCBI
Rnor_6.01131,640,407 - 31,664,067 (+)NCBI
Rnor_5.01135,248,575 - 35,272,235 (+)NCBI
RGSC_v3.41131,454,789 - 31,478,449 (+)RGD
Celera1130,393,241 - 30,416,960 (+)RGD
Sequence:
RefSeq Acc Id: NM_001271316   ⟹   NP_001258245
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21130,725,790 - 30,749,450 (+)NCBI
Rnor_6.01131,640,407 - 31,664,067 (+)NCBI
Rnor_5.01135,248,575 - 35,272,235 (+)NCBI
Celera1130,393,241 - 30,416,960 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017597942   ⟹   XP_017453431
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21130,731,800 - 30,752,227 (+)NCBI
Rnor_6.01131,646,463 - 31,666,839 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039088212   ⟹   XP_038944140
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21130,729,499 - 30,752,227 (+)NCBI
RefSeq Acc Id: XM_039088213   ⟹   XP_038944141
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21130,725,774 - 30,752,227 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_001099363   ⟸   NM_001105893
- Peptide Label: isoform 1 precursor
- UniProtKB: D3ZDS9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001258245   ⟸   NM_001271316
- Peptide Label: isoform 2
- UniProtKB: A0A0G2JXD8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017453431   ⟸   XM_017597942
- Peptide Label: isoform X2
- UniProtKB: A0A0G2JXD8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000070232   ⟸   ENSRNOT00000091472
RefSeq Acc Id: ENSRNOP00000031611   ⟸   ENSRNOT00000029985
RefSeq Acc Id: XP_038944141   ⟸   XM_039088213
- Peptide Label: isoform X2
- UniProtKB: A0A0G2JXD8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944140   ⟸   XM_039088212
- Peptide Label: isoform X1
RefSeq Acc Id: ENSRNOP00000092520   ⟸   ENSRNOT00000102384
Protein Domains
Fibronectin type-III

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZDS9-F1-model_v2 AlphaFold D3ZDS9 1-593 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698054
Promoter ID:EPDNEW_R8579
Type:initiation region
Name:Ifnar1_2
Description:interferon alpha and beta receptor subunit 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R8580  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01131,640,429 - 31,640,489EPDNEW
RGD ID:13698055
Promoter ID:EPDNEW_R8580
Type:initiation region
Name:Ifnar1_1
Description:interferon alpha and beta receptor subunit 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R8579  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01131,640,630 - 31,640,690EPDNEW

Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305399 AgrOrtholog
BioCyc Gene G2FUF-21887 BioCyc
Ensembl Genes ENSRNOG00000028594 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000031611 ENTREZGENE
  ENSRNOP00000031611.5 UniProtKB/TrEMBL
  ENSRNOP00000070232 ENTREZGENE
  ENSRNOP00000070232.1 UniProtKB/TrEMBL
  ENSRNOP00000092520 ENTREZGENE
  ENSRNOP00000092520.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000029985 ENTREZGENE
  ENSRNOT00000029985.7 UniProtKB/TrEMBL
  ENSRNOT00000091472 ENTREZGENE
  ENSRNOT00000091472.2 UniProtKB/TrEMBL
  ENSRNOT00000102384 ENTREZGENE
  ENSRNOT00000102384.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro FN3_sf UniProtKB/TrEMBL
  FN_III UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Interferon_alpha/beta_rcpt_bsu UniProtKB/TrEMBL
KEGG Report rno:288264 UniProtKB/TrEMBL
NCBI Gene 288264 ENTREZGENE
Pfam Interfer-bind UniProtKB/TrEMBL
  Tissue_fac UniProtKB/TrEMBL
PharmGKB IFNAR1 RGD
PhenoGen Ifnar1 PhenoGen
PROSITE FN3 UniProtKB/TrEMBL
SMART FN3 UniProtKB/TrEMBL
Superfamily-SCOP FN_III-like UniProtKB/TrEMBL
UniProt A0A0G2JXD8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AH72_RAT UniProtKB/TrEMBL
  D3ZDS9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-03 Ifnar1  interferon alpha and beta receptor subunit 1  Ifnar1  interferon (alpha, beta and omega) receptor 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-02-26 Ifnar1  interferon (alpha, beta and omega) receptor 1  Ifnar1  interferon (alpha and beta) receptor 1   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Ifnar1  interferon (alpha and beta) receptor 1   Ifnar1_predicted  interferon (alpha and beta) receptor 1 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Ifnar1_predicted  interferon (alpha and beta) receptor 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED