Strain Report - Rat Genome Database

Name: LE- Fmr1 em2Mcwi
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Strain Registration

General

Strain: LE-Fmr1^em2Mcwi

Symbol:

LE-Fmr1^em2Mcwi

Strain:

LE-Fmr1^em2

Substrain:

Mcwi

RGD ID:

11553873

RRID:

RGD_11553873

Ontology ID:

RS:0004246

Alleles:

Fmr1^em2Mcwi

Also known as:

LE-Fmr1em2Mcwi

Type:

mutant

Source:

Generated with support from the Simons Foundation Autism Research Initiative (SFARI ); MCW Gene Editing Rat Resource Center

Origin:

CRISPR/Cas9 system was used to introduce a mutation in the Fmr1 gene of Crl:LE rat embryos. The resulting mutation is a 2-bp insertion in exon 8 of the Fmr1 gene.

Coat Color:

Albino/black hooded

Last Known Status:

Live Animals (as of 2016-10-18)

Research Usage

Autism, ADHD, Developmental delay, Intellectual disability, Epilepsy (from SFARI GENE)

Genotyping Protocol

Download Genotyping Protocol

Position

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	X	154,684,924 - 154,722,369	RGD_MAPPER_PIPELINE	Rnor6.0
Rnor_5.0	1	150,408,220 - 150,445,658	RGD_MAPPER_PIPELINE	Rnor5.0
RGSC_v3.4	X	154,756,031 - 154,793,782	RGD_MAPPER_PIPELINE	RGSC3.4

Highlights

Annotation Click to see Annotation Detail View

References

Region

Additional Information

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Strain: LE-Fmr1em2Mcwi

Strain: LE-Fmr1^em2Mcwi