Scn5a (sodium voltage-gated channel alpha subunit 5) - Rat Genome Database

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Gene: Scn5a (sodium voltage-gated channel alpha subunit 5) Rattus norvegicus
Symbol: Scn5a
Name: sodium voltage-gated channel alpha subunit 5
RGD ID: 3637
Description: Exhibits ankyrin binding activity and fibroblast growth factor binding activity. Involved in several processes, including animal organ development; response to denervation involved in regulation of muscle adaptation; and sodium ion transmembrane transport. Localizes to T-tubule and intercalated disc. Biomarker of brain ischemia and congestive heart failure. Human ortholog(s) of this gene implicated in heart conduction disease (multiple); intrinsic cardiomyopathy (multiple); and sudden infant death syndrome. Orthologous to human SCN5A (sodium voltage-gated channel alpha subunit 5); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; INTERACTS WITH 6-propyl-2-thiouracil; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Nav1.5; SCAL; sodium channel protein cardiac muscle subunit alpha; sodium channel protein type 5 subunit alpha; sodium channel protein type V subunit alpha; sodium channel, voltage-gated, type 5, alpha subunit; sodium channel, voltage-gated, type V, alpha; sodium channel, voltage-gated, type V, alpha polypeptide; sodium channel, voltage-gated, type V, alpha subunit; voltage-gated sodium channel Nav1.5c; voltage-gated sodium channel subunit alpha Nav1.5
RGD Orthologs
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: Scn5aem2Mcwi  
Genetic Models: DA-Scn5aem2Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
mRatBN7.28119,220,905 - 119,318,816 (-)NCBI
Rnor_6.0 Ensembl8128,169,191 - 128,266,639 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.08128,169,191 - 128,266,681 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.08127,375,781 - 127,471,879 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48124,446,479 - 124,545,301 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.18124,467,115 - 124,565,038 (-)NCBI
Celera8118,371,960 - 118,468,948 (-)NCBICelera
RH 3.4 Map81282.5RGD
Cytogenetic Map8q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)