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Gene: Mmp9 (matrix metallopeptidase 9) Rattus norvegicus
Symbol: Mmp9
Name: matrix metallopeptidase 9
Description: Exhibits fibronectin binding activity and metallopeptidase activity. Involved in several processes, including cellular response to cell-matrix adhesion; cellular response to cytokine stimulus; and cellular response to iron(III) ion. Localizes to extracellular space and protein-containing complex. Used to study artery disease (multiple); brain ischemia (multiple); congestive heart failure; glomerulosclerosis; and lung disease (multiple). Biomarker of several diseases, including artery disease (multiple); brain disease (multiple); chronic obstructive pulmonary disease (multiple); glucose metabolism disease (multiple); and kidney disease (multiple). Human ortholog(s) of this gene implicated in several diseases, including Down syndrome; anodontia; artery disease (multiple); autoimmune hypersensitivity disease (multiple); and chronic obstructive pulmonary disease (multiple). Orthologous to human MMP9 (matrix metallopeptidase 9); PARTICIPATES IN fibroblast growth factor signaling pathway; syndecan signaling pathway; urinary bladder cancer pathway; INTERACTS WITH (+)-Tetrandrine; (R)-carnitine; (R)-noradrenaline.
Type: protein-coding
Also known as: 92 kDa gelatinase; 92 kDa type IV collagenase; 92-kDa type IV collagenase; gelatinase B; GELB; matrix metalloproteinase 9 (gelatinase B 92-kDa type IV collagenase); matrix metalloproteinase 9 (gelatinase B, 92-kDa type IV collagenase); matrix metalloproteinase-9; MMP-9
Homo sapiens (human) : MMP9 (matrix metallopeptidase 9)  HGNC  Alliance
Mus musculus (house mouse) : Mmp9 (matrix metallopeptidase 9)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mmp9 (matrix metallopeptidase 9)
Pan paniscus (bonobo/pygmy chimpanzee) : MMP9 (matrix metallopeptidase 9)
Canis lupus familiaris (dog) : MMP9 (matrix metallopeptidase 9)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mmp9 (matrix metallopeptidase 9)
Sus scrofa (pig) : MMP9 (matrix metallopeptidase 9)
Chlorocebus sabaeus (African green monkey) : MMP9 (matrix metallopeptidase 9)
Heterocephalus glaber (naked mole-rat) : Mmp9 (matrix metallopeptidase 9)
more info ...
Allele / Splice: Mmp9em6Mcwi   Mmp9em4Mcwi  
Genetic Models: SS-Mmp9em4Mcwi SS-Mmp9em6Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.03161,413,410 - 161,421,473 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3161,413,298 - 161,421,520 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03167,578,904 - 167,605,890 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43155,985,473 - 155,993,433 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13155,891,508 - 155,899,467 (+)NCBI
Celera3152,289,466 - 152,297,426 (+)NCBICelera
Cytogenetic Map3q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations