Cm97 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Cm97 (Cardiac mass QTL 97) Rattus norvegicus

Symbol: Cm97
Name: Cardiac mass QTL 97
RGD ID: 12879872
Previously known as: BpcakmC3QTL3
Trait: heart left ventricle mass   (VT:0007031)    
Measurement Type: heart left ventricle weight to body weight ratio   (CMO:0000530)    
LOD Score: Not Available
P Value: 0.001
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr83141,555,229 - 186,555,229RGD_MAPPER_PIPELINE
mRatBN7.23145,925,360 - 166,177,555RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.03153,381,237 - 174,632,112RGD_MAPPER_PIPELINERnor6.0
Rnor_5.03158,115,782 - 182,470,017RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.43147,852,788 - 168,149,595RGD_MAPPER_PIPELINERGSC3.4
Cross Type: Not Available
Strains Crossed: SS.LEW-(D3Rat61-D3Wox1)/Ayd 
JBrowse: View Region in Genome Browser (JBrowse)
Model




  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cm97Rathypertension  IAGP 1599557 RGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cm97Ratabnormal heart left ventricle weight  IAGP 1599557 RGD 

Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cm97Ratheart left ventricle weight to body weight ratio  IDA 1599557 RGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cm97Ratcontrolled sodium content diet  IDA 1599557 RGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cm97Ratpost excision weight measurement  IDA 1599557 RGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cm97RatSS.LEW-(D3Rat61-D3Wox1)/Ayd  IEA 1599557 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Cm97Ratheart left ventricle mass  IDA 1599557 RGD 


#
Reference Title
Reference Citation
1. Distinct quantitative trait loci for kidney, cardiac, and aortic mass dissociated from and associated with blood pressure in Dahl congenic rats. Duong C, etal., Mamm Genome. 2006 Dec;17(12):1147-61. Epub 2006 Dec 1.


1 to 20 of 378 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
2321481Mroh8maestro heat-like repeat family member 83145873995145942439Rat
62075Rpn2ribophorin II3145941787145989271Rat
61883Ghrhgrowth hormone releasing hormone3145992762146012528Rat
1561447Manbalmannosidase beta like3146035082146064676Rat
11400670LOC108350508uncharacterized LOC1083505083146086851146091815Rat
620795SrcSRC proto-oncogene, non-receptor tyrosine kinase3146091969146139492Rat
621666BlcapBLCAP, apoptosis inducing factor3146222699146232859Rat
620155Nnatneuronatin3146225941146228868Rat
11479204LOC108350620uncharacterized LOC1083506203146304258146306205Rat
40999503LOC120101772uncharacterized LOC1201017723146327117146346813Rat
1563558Ctnnbl1catenin, beta like 13146387940146548987Rat
41257292Mpc1l-ps3mitochondrial pyruvate carrier 1-like, pseudogene 33146410248146410689Rat
1305725Vstm2lV-set and transmembrane domain containing 2 like3146571099146600930Rat
1562582Tti1TELO2 interacting protein 13146639048146682945Rat
1304782Rprd1bregulation of nuclear pre-mRNA domain containing 1B3146682975146729251Rat
11491028LOC108350509uncharacterized LOC1083505093146732293146733569Rat
621081Tgm2transglutaminase 23146772684146801924Rat
1563354Kiaa1755KIAA1755 ortholog3146850558146884238Rat
1303179Bpibactericidal/permeability-increasing protein3146909626146936487Rat
61865Lbplipopolysaccharide binding protein3146953889146981032Rat

1 to 20 of 378 rows
1 to 20 of 478 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
10501D3Mco33533163577121163577474Ratregion
10502D3Mgh101083159898684159898795Ratregion
11191D3Wox61303156687232156687364Ratregion
34178D3Mgh231393162184655162184794Ratregion
34240D3Mgh11483161695835161695983Ratregion
34296D3Mgh241163152593496152593614Ratregion
34304D3Mgh181553154135827154135982Ratregion
34316D3Mgh21613155617360155617519Ratregion
34682D9Mit101503161935792161935942Ratregion
11278D3Arb122783153156423153156701Ratregion
11363D3Wox71793152914821152915000Ratregion
11365D3Arb132113152914793152915004Ratregion
11366D3Mgh31243152952649152952773Ratregion
37372D3Rat2362083150610883150611091Ratregion
35356D3Rat51613146592722146592883Ratregion
35378D3Rat611333145925360145925493Ratregion
35378D3Rat611333145925360145925493Ratregion
35404D3Rat601513149199787149199938Ratregion
37912D3Rat1992373156990411156990649Ratregion
37980D3Rat1142133147415594147415807Ratregion
1 to 20 of 478 rows

Flank 1: (D3Rat61)
Rat AssemblyChrPosition (strand)Source
mRatBN7.23145,925,360 - 145,925,493 (+)MAPPER
mRatBN7.23145,925,360 - 145,925,493 (-)MAPPER
Rnor_6.03153,650,444 - 153,650,576NCBI
Rnor_6.03153,381,237 - 153,381,369NCBI
Rnor_5.03158,115,782 - 158,115,914UniSTS
Rnor_5.03158,338,509 - 158,338,641UniSTS
RGSC_v3.43147,852,788 - 147,852,921RGD
RGSC_v3.43147,852,789 - 147,852,921UniSTS
RGSC_v3.13147,758,698 - 147,758,830RGD
Celera3144,631,052 - 144,631,184UniSTS
RH 3.4 Map31342.7RGD
RH 3.4 Map31342.7UniSTS
RH 2.0 Map3902.5RGD
FHH x ACI Map386.9299RGD
Flank 2: (D3Wox1)
Rat AssemblyChrPosition (strand)Source
GRCr83186,555,022 - 186,555,229 (+)Marker Load Pipeline
mRatBN7.23166,177,348 - 166,177,555 (+)MAPPER
Rnor_6.03174,631,906 - 174,632,112NCBI
Rnor_5.03182,469,811 - 182,470,017UniSTS
RGSC_v3.43168,149,388 - 168,149,595RGD
RGSC_v3.43168,149,389 - 168,149,595UniSTS
RGSC_v3.13168,055,425 - 168,055,631RGD
Celera3166,390,198 - 166,390,404UniSTS
RH 3.4 Map31512.7UniSTS
RH 3.4 Map31512.7RGD
RH 2.0 Map31024.5RGD
Cytogenetic Map3 RGD


1 to 10 of 46 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
12879876Bw182Body weight QTL 1820.003body mass (VT:0001259)body weight (CMO:0000012)3145925360166177555Rat
2301411Bp320Blood pressure QTL 3200.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3145925360166177555Rat
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
1300113Bp176Blood pressure QTL 1763.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3145956084157309487Rat
12879872Cm97Cardiac mass QTL 970.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3145925360166177555Rat
1598877Bp285Blood pressure QTL 2851.50.03arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3120538241165538241Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3130656562169034231Rat
12879873Cm96Cardiac mass QTL 960.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)3145925360166177555Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
12879874Cm98Cardiac mass QTL 980.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)3145925360166177555Rat

1 to 10 of 46 rows


Note Type Note Reference
qtl_general number of animals used: 5 gender: male 1599557
qtl_general also affects cardiac mass, heart right ventricle mass, aortic mass, kidney mass, blood pressure and body mass 1599557
qtl_map 10 Mb 1599557
qtl_statistics_details software package used: ANOVA followed by Dunnett test in the SYSTAT 9 program 1599557
qtl_trait_method measurement method: selected males were weaned at 21 days of age then fed 2% NaCl diet starting from 35 days of age, at 14 weeks animals were decapitated, organs removed, blotted and weighed 1599557
qtl_trait_method heart was dissected into left ventricle plus septum and right ventricle 1599557