Ube2c (ubiquitin-conjugating enzyme E2C) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Ube2c (ubiquitin-conjugating enzyme E2C) Rattus norvegicus
Analyze
Symbol: Ube2c
Name: ubiquitin-conjugating enzyme E2C
RGD ID: 1305382
Description: Predicted to enable ubiquitin conjugating enzyme activity and ubiquitin-like protein ligase binding activity. Predicted to contribute to ubiquitin-protein transferase activity. Predicted to be involved in several processes, including anaphase-promoting complex-dependent catabolic process; protein polyubiquitination; and regulation of mitotic cell cycle phase transition. Predicted to be located in cytosol and plasma membrane. Predicted to be part of anaphase-promoting complex. Predicted to be active in nucleus. Orthologous to human UBE2C (ubiquitin conjugating enzyme E2 C); PARTICIPATES IN ubiquitin/proteasome degradation pathway; INTERACTS WITH 1,3-dinitrobenzene; 1-naphthyl isothiocyanate; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC296368; ubiquitin-conjugating enzyme E2 C
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23153,506,636 - 153,509,036 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3153,506,636 - 153,513,339 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3157,315,317 - 157,317,718 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.03165,814,287 - 165,816,688 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.03163,558,064 - 163,560,465 (+)NCBIRnor_WKY
Rnor_6.03161,236,971 - 161,239,371 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3161,236,898 - 161,241,159 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03167,422,569 - 167,424,969 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43155,800,357 - 155,802,757 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13155,706,427 - 155,708,790 (+)NCBI
Celera3152,114,392 - 152,116,792 (+)NCBICelera
Cytogenetic Map3q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
(S)-nicotine  (ISO)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (ISO)
1,1-dichloroethene  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1,3-dinitrobenzene  (EXP)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3-dimethoxynaphthalene-1,4-dione  (ISO)
2,4-diaminotoluene  (ISO)
2-acetamidofluorene  (EXP,ISO)
2-Hydroxy-6-(8,11,14-pentadecatrienyl)benzoic acid  (ISO)
2-methylcholine  (ISO)
3-methylcholanthrene  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-azacytidine  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
7,12-dimethyltetraphene  (ISO)
acetamide  (EXP)
aflatoxin B1  (EXP)
all-trans-retinoic acid  (ISO)
amsacrine  (ISO)
antimony(0)  (ISO)
antimycin A  (ISO)
Aroclor 1254  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
azathioprine  (ISO)
azoxystrobin  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
beta-naphthoflavone  (ISO)
bicalutamide  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
buspirone  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
cefaloridine  (EXP)
chloroprene  (ISO)
choline  (ISO)
chromium atom  (ISO)
cis-caffeic acid  (ISO)
cisplatin  (EXP,ISO)
cobalt dichloride  (EXP,ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
corticosterone  (EXP)
Cuprizon  (EXP)
curcumin  (ISO)
cyclosporin A  (ISO)
cytarabine  (ISO)
decabromodiphenyl ether  (ISO)
deguelin  (ISO)
deoxynivalenol  (ISO)
diarsenic trioxide  (ISO)
diazinon  (EXP)
dibenz[a,h]anthracene  (ISO)
dibutyl phthalate  (ISO)
dieldrin  (EXP)
diethylstilbestrol  (EXP)
dimethyl sulfoxide  (ISO)
dioxygen  (ISO)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (ISO)
disodium selenite  (ISO)
doxorubicin  (ISO)
enzalutamide  (ISO)
etoposide  (ISO)
fenpyroximate  (ISO)
folic acid  (ISO)
furan  (EXP)
gemcitabine  (ISO)
genistein  (ISO)
gentamycin  (EXP)
geraniol  (ISO)
hydrogen peroxide  (ISO)
hydroxyurea  (ISO)
indole-3-methanol  (EXP)
irinotecan  (EXP,ISO)
ivermectin  (ISO)
L-methionine  (ISO)
leflunomide  (EXP,ISO)
lidocaine  (EXP)
lithium atom  (EXP)
lithium hydride  (EXP)
menadione  (ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
methamphetamine  (EXP)
methapyrilene  (EXP)
methotrexate  (EXP,ISO)
methylmercury chloride  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-methyl-N-nitrosourea  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
nickel dichloride  (ISO)
niclosamide  (ISO)
nicotine  (ISO)
nimesulide  (EXP)
ochratoxin A  (EXP)
oxaliplatin  (EXP)
ozone  (ISO)
palbociclib  (ISO)
paracetamol  (EXP,ISO)
PCB138  (ISO)
phenformin  (EXP)
phenobarbital  (ISO)
PhIP  (EXP)
picoxystrobin  (ISO)
pirinixic acid  (ISO)
potassium dichromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
propanal  (ISO)
propiconazole  (ISO)
pyrimidifen  (ISO)
rotenone  (EXP,ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
Soman  (EXP)
sunitinib  (ISO)
tamoxifen  (ISO)
tebufenpyrad  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (EXP,ISO)
tetrachloromethane  (EXP,ISO)
thalidomide  (ISO)
thapsigargin  (ISO)
thifluzamide  (ISO)
thioacetamide  (EXP)
titanium dioxide  (EXP,ISO)
topotecan  (EXP)
trans-caffeic acid  (ISO)
trichloroethene  (EXP,ISO)
trimellitic anhydride  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
trovafloxacin  (EXP)
tubocurarine  (ISO)
tunicamycin  (ISO)
valdecoxib  (EXP)
vincristine  (ISO)
zaragozic acid A  (EXP,ISO)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9122200   PMID:12629039   PMID:15749827   PMID:17167411   PMID:18485873   PMID:19820702   PMID:19822757   PMID:20061386   PMID:21448667  


Genomics

Comparative Map Data
Ube2c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23153,506,636 - 153,509,036 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3153,506,636 - 153,513,339 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3157,315,317 - 157,317,718 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.03165,814,287 - 165,816,688 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.03163,558,064 - 163,560,465 (+)NCBIRnor_WKY
Rnor_6.03161,236,971 - 161,239,371 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3161,236,898 - 161,241,159 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03167,422,569 - 167,424,969 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43155,800,357 - 155,802,757 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13155,706,427 - 155,708,790 (+)NCBI
Celera3152,114,392 - 152,116,792 (+)NCBICelera
Cytogenetic Map3q42NCBI
UBE2C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382045,812,644 - 45,816,952 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl2045,812,576 - 45,816,957 (+)EnsemblGRCh38hg38GRCh38
GRCh372044,441,283 - 44,445,591 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362043,874,662 - 43,879,003 (+)NCBINCBI36Build 36hg18NCBI36
Build 342043,874,661 - 43,879,001NCBI
Celera2041,151,754 - 41,156,092 (+)NCBICelera
Cytogenetic Map20q13.12NCBI
HuRef2041,183,027 - 41,187,357 (+)NCBIHuRef
CHM1_12044,344,397 - 44,348,735 (+)NCBICHM1_1
T2T-CHM13v2.02047,549,141 - 47,553,438 (+)NCBIT2T-CHM13v2.0
Ube2c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392164,611,849 - 164,614,822 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2164,611,818 - 164,620,742 (+)EnsemblGRCm39 Ensembl
GRCm382164,769,929 - 164,772,902 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2164,769,898 - 164,778,822 (+)EnsemblGRCm38mm10GRCm38
MGSCv372164,595,429 - 164,598,402 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362164,461,134 - 164,464,107 (+)NCBIMGSCv36mm8
Celera2170,707,443 - 170,710,416 (+)NCBICelera
Cytogenetic Map2H3NCBI
cM Map285.27NCBI
Ube2c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544511,469,063 - 11,478,759 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544511,474,826 - 11,479,479 (-)NCBIChiLan1.0ChiLan1.0
UBE2C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12043,239,382 - 43,243,464 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2043,239,382 - 43,243,464 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02042,152,219 - 42,156,246 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
UBE2C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12433,128,300 - 33,133,637 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2433,128,335 - 33,132,023 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2432,655,563 - 32,659,463 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02433,838,609 - 33,842,717 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2433,838,625 - 33,842,523 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12433,097,372 - 33,101,272 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02433,212,448 - 33,216,354 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02433,751,584 - 33,755,488 (+)NCBIUU_Cfam_GSD_1.0
Ube2c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640191,750,684 - 191,753,998 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365147,199,539 - 7,207,655 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049365147,204,332 - 7,208,340 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UBE2C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1748,018,400 - 48,021,534 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11748,018,403 - 48,021,542 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21753,664,459 - 53,667,609 (+)NCBISscrofa10.2Sscrofa10.2susScr3
UBE2C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1218,069,525 - 18,073,597 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605066,709,872 - 66,713,957 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ube2c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247908,751,662 - 8,760,057 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247908,756,758 - 8,760,078 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ube2c
5 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:34
Count of miRNA genes:27
Interacting mature miRNAs:32
Transcripts:ENSRNOT00000020323
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)394856903159898684Rat
2312659Slep7Serum leptin concentration QTL 70.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)398535255168026850Rat
2312670Bw94Body weight QTL 940.01inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)398535255168026850Rat
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3112681431157681431Rat
1576306Schws3Schwannoma susceptibility QTL 30.001nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)3118839124163839124Rat
1598877Bp285Blood pressure QTL 2851.50.03arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3120538241165538241Rat
1300159Kidm4Kidney mass QTL 43.83kidney mass (VT:0002707)right kidney wet weight to body weight ratio (CMO:0001953)3121056165157309487Rat
10755461Coatc16Coat color QTL 16coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)3122438700167438700Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3124122556169034231Rat
2303620Vencon4Ventilatory control QTL 43.9respiration trait (VT:0001943)tidal volume (CMO:0000222)3127162703168026850Rat
631673Iddm13Insulin dependent diabetes mellitus QTL 131.30.663blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)3130193298161695983Rat
1578656Vnigr2Vascular neointimal growth QTL 24.2artery morphology trait (VT:0002191)lesioned artery residual lumen area (CMO:0001417)3130656562169034231Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3130656562169034231Rat
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3131635904169034231Rat
2298477Eau4Experimental allergic uveoretinitis QTL 40.0011uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)3137398739169034231Rat
8552952Pigfal13Plasma insulin-like growth factor 1 level QTL 13blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)3138799500169034231Rat
1298068Bp167Blood pressure QTL 1670.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3141074471169034231Rat
1331726Bp208Blood pressure QTL 2083.129arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3141339013162184794Rat
61335Bp20Blood pressure QTL 203arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3141339236155617360Rat
2317883Alcrsp26Alcohol response QTL 261.80.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)3145526770169034231Rat
12879871Am7Aortic mass QTL 70.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)3145925360166177555Rat
12879872Cm97Cardiac mass QTL 970.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3145925360166177555Rat
12879873Cm96Cardiac mass QTL 960.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)3145925360166177555Rat
12879874Cm98Cardiac mass QTL 980.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)3145925360166177555Rat
12879875Kidm64Kidney mass QTL 640.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3145925360166177555Rat
12879876Bw182Body weight QTL 1820.003body mass (VT:0001259)body weight (CMO:0000012)3145925360166177555Rat
2301411Bp320Blood pressure QTL 3200.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3145925360166177555Rat
1300113Bp176Blood pressure QTL 1763.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3145956084157309487Rat
1598854Memor10Memory QTL 102exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)3145956084161299569Rat
8552791Vie2Viral induced encephalitis QTL 24.1brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)3145956084169034231Rat
1578666Vnigr1Vascular neointimal growth QTL 14.6artery morphology trait (VT:0002191)artery lumen area (CMO:0001409)3149040888168026850Rat

Markers in Region
RH141512  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23153,505,203 - 153,505,353 (+)MAPPERmRatBN7.2
Rnor_6.03161,235,539 - 161,235,688NCBIRnor6.0
Rnor_5.03167,421,137 - 167,421,286UniSTSRnor5.0
RGSC_v3.43155,798,925 - 155,799,074UniSTSRGSC3.4
Celera3152,112,960 - 152,113,109UniSTS
RH 3.4 Map31422.8UniSTS
Cytogenetic Map3q42UniSTS
RH128158  
Rat AssemblyChrPosition (strand)SourceJBrowse
RH 3.4 Map31426.8UniSTS
Cytogenetic Map3q42UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 26 28 22 14 22 34 18 34
Low 12 20 12 5 12 8 11 27 14 7 11 8
Below cutoff 5 9 7 7 13 3

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000020323   ⟹   ENSRNOP00000020323
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3153,506,636 - 153,509,036 (+)Ensembl
Rnor_6.0 Ensembl3161,236,971 - 161,239,371 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000082303   ⟹   ENSRNOP00000074117
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl3161,236,898 - 161,241,159 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000104083   ⟹   ENSRNOP00000081343
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3153,506,897 - 153,509,036 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000118238   ⟹   ENSRNOP00000088133
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3153,506,636 - 153,513,339 (+)Ensembl
RefSeq Acc Id: NM_001106542   ⟹   NP_001100012
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23153,506,636 - 153,509,036 (+)NCBI
Rnor_6.03161,236,971 - 161,239,371 (+)NCBI
Rnor_5.03167,422,569 - 167,424,969 (+)NCBI
RGSC_v3.43155,800,357 - 155,802,757 (+)RGD
Celera3152,114,392 - 152,116,792 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001100012 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL96497 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001100012   ⟸   NM_001106542
- UniProtKB: D3ZUW6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000074117   ⟸   ENSRNOT00000082303
RefSeq Acc Id: ENSRNOP00000020323   ⟸   ENSRNOT00000020323
RefSeq Acc Id: ENSRNOP00000088133   ⟸   ENSRNOT00000118238
RefSeq Acc Id: ENSRNOP00000081343   ⟸   ENSRNOT00000104083
Protein Domains
UBC core

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZUW6-F1-model_v2 AlphaFold D3ZUW6 1-179 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692664
Promoter ID:EPDNEW_R3188
Type:initiation region
Name:Ube2c_1
Description:ubiquitin-conjugating enzyme E2C
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03161,236,975 - 161,237,035EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305382 AgrOrtholog
BioCyc Gene G2FUF-46830 BioCyc
BioCyc Pathway PWY-7511 [protein ubiquitination] BioCyc
Ensembl Genes ENSRNOG00000015131 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000020323 ENTREZGENE
  ENSRNOP00000020323.2 UniProtKB/TrEMBL
  ENSRNOP00000081343.1 UniProtKB/TrEMBL
  ENSRNOP00000088133.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000020323 ENTREZGENE
  ENSRNOT00000020323.4 UniProtKB/TrEMBL
  ENSRNOT00000104083.1 UniProtKB/TrEMBL
  ENSRNOT00000118238.1 UniProtKB/TrEMBL
Gene3D-CATH 3.10.110.10 UniProtKB/TrEMBL
InterPro UBQ-conjugat/RWD-like UniProtKB/TrEMBL
  UBQ-conjugat_E2 UniProtKB/TrEMBL
  UBQ-conjugating_AS UniProtKB/TrEMBL
KEGG Report rno:296368 UniProtKB/TrEMBL
NCBI Gene 296368 ENTREZGENE
Pfam UQ_con UniProtKB/TrEMBL
PhenoGen Ube2c PhenoGen
PROSITE UBIQUITIN_CONJUGAT_1 UniProtKB/TrEMBL
  UBIQUITIN_CONJUGAT_2 UniProtKB/TrEMBL
Superfamily-SCOP UBQ-conjugat/RWD-like UniProtKB/TrEMBL
UniProt A0A8I6A5K3_RAT UniProtKB/TrEMBL
  A0A8I6G5T8_RAT UniProtKB/TrEMBL
  D3ZUW6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Ube2c  ubiquitin-conjugating enzyme E2C   Ube2c_predicted  ubiquitin-conjugating enzyme E2C (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Ube2c_predicted  ubiquitin-conjugating enzyme E2C (predicted)      Symbol and Name status set to approved 70820 APPROVED