Vnigr1 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL Registration

QTL: Vnigr1 (Vascular neointimal growth QTL 1) Rattus norvegicus

Symbol: Vnigr1
Name: Vascular neointimal growth QTL 1
RGD ID: 1578666
Trait: artery morphology trait   (VT:0002191)    
Measurement Type: artery lumen area   (CMO:0001409)    
LOD Score: 4.6
P Value: Not Available
Variance: Not Available
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr83151,075,912 - 189,428,310RGD_MAPPER_PIPELINE
mRatBN7.23149,040,888 - 168,026,850RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.03156,381,661 - 176,418,101RGD_MAPPER_PIPELINERnor6.0
Rnor_5.03162,615,336 - 180,128,021RGDRnor5.0
RGSC_v3.43151,160,532 - 170,016,653RGDRGSC3.4
RGSC_v3.13151,066,442 - 169,922,503RGD
Cross Type: Not Available
Strains Crossed: BN/SsNHsd SHR/NHsd 
JBrowse: View Region in Genome Browser (JBrowse)
Model




  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Vnigr1RatHyperplasia  IAGP 1578306 RGD 


Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Vnigr1Ratartery lumen area  IDA 1578306 RGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Vnigr1Ratballoon angioplasty  IDA 1578306 RGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Vnigr1Ratex vivo light microscopy with digital image analysis  IDA 1578306 RGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Vnigr1RatBN/SsNHsd  IEA 1578306 RGD 
Vnigr1RatSHR/NHsd  IEA 1578306 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Vnigr1Ratartery morphology trait  IDA 1578306 RGD 


#
Reference Title
Reference Citation
1. Linkage Analysis of Neointimal Hyperplasia and Vascular Wall Transformation Following Balloon Angioplasty. Nestor AL, etal., Physiol Genomics. 2006 Jan 24;.


1 to 20 of 367 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
7526217LOC102550898uncharacterized LOC1025508983149197582149204111Rat
7578813LOC102550999uncharacterized LOC1025509993149214619149276915Rat
9450932LOC103691948uncharacterized LOC1036919483149283224149290405Rat
621246Top1DNA topoisomerase I3149293469149376618Rat
7588290LOC102551164uncharacterized LOC1025511643149376458149385570Rat
3347Plcg1phospholipase C, gamma 13149385587149416330Rat
631431Zhx3zinc fingers and homeoboxes 33149417787149548671Rat
1588534Lpin3lipin 33149533719149558494Rat
1309607Emilin3elastin microfibril interfacer 33149558785149564785Rat
1310465Chd6chromodomain helicase DNA binding protein 63149596509149757765Rat
41102028LOC120102052small nucleolar RNA SNORA173149644352149644484Rat
11488586LOC108350515uncharacterized LOC1083505153149771791149807094Rat
40932337LOC120101777uncharacterized LOC1201017773150167127150174708Rat
1309653Ptprtprotein tyrosine phosphatase, receptor type, T3150189343151288145Rat
40961177LOC120101926uncharacterized LOC1201019263151060130151070987Rat
41321799LOC120101925uncharacterized LOC1201019253151286340151298063Rat
7599447LOC102547303uncharacterized LOC1025473033151346470151358385Rat
41289034LOC120102062small nucleolar RNA SNORA173151394507151394629Rat
11516994LOC108350621uncharacterized LOC1083506213151538876151540615Rat
1588363Rpl28-ps6ribosomal protein L28, pseudogene 63151557942151558349Rat

1 to 20 of 367 rows
1 to 20 of 487 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
10501D3Mco33533163577121163577474Ratregion
10502D3Mgh101083159898684159898795Ratregion
11191D3Wox61303156687232156687364Ratregion
34178D3Mgh231393162184655162184794Ratregion
34240D3Mgh11483161695835161695983Ratregion
34296D3Mgh241163152593496152593614Ratregion
34304D3Mgh181553154135827154135982Ratregion
34316D3Mgh21613155617360155617519Ratregion
34682D9Mit101503161935792161935942Ratregion
11278D3Arb122783153156423153156701Ratregion
11363D3Wox71793152914821152915000Ratregion
11365D3Arb132113152914793152915004Ratregion
11366D3Mgh31243152952649152952773Ratregion
37372D3Rat2362083150610883150611091Ratregion
35404D3Rat601513149199787149199938Ratregion
37912D3Rat1992373156990411156990649Ratregion
36410D3Mgh301413151079974151080115Ratregion
36616D3Rat21743162581869162582043Ratregion
36745D3Rat11593168026691168026850Ratregion
36759D3Rat591373161299432161299569Ratregion
1 to 20 of 487 rows

Flank 1: (D3Rat145)
Rat AssemblyChrPosition (strand)Source
mRatBN7.23149,040,888 - 149,041,023 (+)MAPPER
Rnor_6.03156,381,661 - 156,381,795NCBI
Rnor_5.03162,615,336 - 162,615,470UniSTS
RGSC_v3.43151,160,532 - 151,160,667RGD
RGSC_v3.43151,160,533 - 151,160,667UniSTS
RGSC_v3.13151,066,442 - 151,066,576RGD
Celera3147,718,594 - 147,718,728UniSTS
RH 3.4 Map31366.7UniSTS
RH 3.4 Map31366.7RGD
SHRSP x BN Map375.5299UniSTS
SHRSP x BN Map375.5299RGD
Peak: (D3Arb12)
Rat AssemblyChrPosition (strand)Source
GRCr83173,575,773 - 173,576,051 (+)Marker Load Pipeline
mRatBN7.23153,156,423 - 153,156,701 (+)MAPPER
Rnor_6.03160,874,038 - 160,874,317NCBI
Rnor_5.03167,054,324 - 167,054,603UniSTS
RGSC_v3.43155,447,672 - 155,447,952RGD
RGSC_v3.43155,447,673 - 155,447,952UniSTS
RGSC_v3.13155,353,708 - 155,353,988RGD
Celera3151,767,761 - 151,768,034UniSTS
RH 3.4 Map31426.6UniSTS
RH 3.4 Map31426.6RGD
RH 2.0 Map3980.6RGD
SHRSP x BN Map379.9099RGD
Cytogenetic Map3q42UniSTS
Flank 2: (D3Rat1)
Rat AssemblyChrPosition (strand)Source
mRatBN7.23168,026,691 - 168,026,850 (+)MAPPER
Rnor_6.03176,417,943 - 176,418,101NCBI
Rnor_5.03180,127,863 - 180,128,021UniSTS
RGSC_v3.43170,016,309 - 170,016,467UniSTS
RGSC_v3.43170,016,252 - 170,016,653RGD
RGSC_v3.13169,922,345 - 169,922,503RGD
Celera3164,558,222 - 164,558,366UniSTS
RH 3.4 Map31533.2RGD
RH 3.4 Map31533.2UniSTS
RH 2.0 Map31027.1RGD
SHRSP x BN Map391.5299RGD
FHH x ACI Map3104.89RGD
Cytogenetic Map3q43UniSTS


1 to 10 of 41 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
12879876Bw182Body weight QTL 1820.003body mass (VT:0001259)body weight (CMO:0000012)3145925360166177555Rat
2301411Bp320Blood pressure QTL 3200.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3145925360166177555Rat
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
1300113Bp176Blood pressure QTL 1763.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3145956084157309487Rat
12879872Cm97Cardiac mass QTL 970.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3145925360166177555Rat
1598877Bp285Blood pressure QTL 2851.50.03arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3120538241165538241Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3130656562169034231Rat
12879873Cm96Cardiac mass QTL 960.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)3145925360166177555Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
12879874Cm98Cardiac mass QTL 980.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)3145925360166177555Rat

1 to 10 of 41 rows


Note Type Note Reference
qtl_map Suggestive QTL for neointimal growth were identified on chromosomes RNO3, RNO4, RNO6, RNO15 1578306