Eppin (epididymal peptidase inhibitor) - Rat Genome Database

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Gene: Eppin (epididymal peptidase inhibitor) Rattus norvegicus
Analyze
Symbol: Eppin
Name: epididymal peptidase inhibitor
RGD ID: 1597722
Description: Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in several processes, including negative regulation of calcium ion import; negative regulation of flagellated sperm motility; and negative regulation of peptidase activity. Predicted to be located in acrosomal vesicle and cell surface. Predicted to be part of protein-containing complex. Predicted to be active in extracellular space. Orthologous to human EPPIN-WFDC6 (EPPIN-WFDC6 readthrough) and EPPIN (epididymal peptidase inhibitor); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; amitrole.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: epididymal protease inhibitor; LOC685161; serine peptidase inhibitor-like, with Kunitz and WAP domains 1 (eppin); serine protease inhibitor-like with Kunitz and WAP domains 1; serine protease inhibitor-like, with Kunitz and WAP domains 1 (eppin); similar to Eppin precursor (Epididymal protease inhibitor) (Serine protease inhibitor-like with Kunitz and WAP domains 1); Spinlw1; WAP four-disulfide core domain protein 8; Wfdc8
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83173,731,739 - 173,738,651 (-)NCBIGRCr8
mRatBN7.23153,312,396 - 153,319,310 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3153,312,396 - 153,319,310 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3157,122,394 - 157,129,304 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03165,621,354 - 165,628,265 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03163,364,985 - 163,371,894 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03161,043,761 - 161,050,550 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3161,041,727 - 161,050,557 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03167,222,870 - 167,229,659 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43155,607,326 - 155,614,193 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera3151,921,822 - 151,928,632 (-)NCBICelera
Cytogenetic Map3q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
EppinRatadenosine deaminase deficiency  ISORGD:13153168554872ClinVar Annotator: match by term: Severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, NK more ...ClinVarPMID:26255240|PMID:26376800|PMID:28492532
EppinRatfocal epilepsy  ISORGD:13153168554872ClinVar Annotator: match by term: Focal-onset seizureClinVarPMID:32581362
EppinRatT-Cell Immunodeficiency, Recurrent Infections, and Autoimmunity with or without Cardiac Malformations  ISORGD:13153168554872ClinVar Annotator: match by term: T-cell immunodeficiency, recurrent infections, and autoimmunity with or without cardiac more ...ClinVarPMID:22174160|PMID:28492532

1 to 20 of 35 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
EppinRat1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactionsISORGD:13153176480464[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ...CTDPMID:25510870
EppinRat17beta-hydroxy-17-methylestra-4,9,11-trien-3-one multiple interactionsISORGD:13153176480464Metribolone inhibits the reaction [Ketoconazole results in decreased expression of EPPIN mRNA]CTDPMID:19587329
EppinRat2,2',4,4',5,5'-hexachlorobiphenyl multiple interactionsISORGD:13153176480464[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ...CTDPMID:25510870
EppinRat2,2',5,5'-tetrachlorobiphenyl multiple interactionsISORGD:13153176480464[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ...CTDPMID:25510870
EppinRat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of EPPIN mRNACTDPMID:33387578
EppinRat2,4,4'-trichlorobiphenyl multiple interactionsISORGD:13153176480464[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ...CTDPMID:25510870
EppinRat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of EPPIN mRNACTDPMID:30047161
EppinRataflatoxin B1 increases methylationISORGD:13153166480464Aflatoxin B1 results in increased methylation of EPPIN geneCTDPMID:27153756
EppinRatall-trans-retinoic acid multiple interactionsISORGD:13153176480464[mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in decreased expression of EPPIN mRNACTDPMID:36189433
EppinRatall-trans-retinoic acid decreases expressionISORGD:13153176480464Tretinoin results in decreased expression of EPPIN mRNACTDPMID:36189433
EppinRatamitrole decreases expressionEXP 6480464Amitrole results in decreased expression of EPPIN mRNACTDPMID:30047161
EppinRatbenzo[a]pyrene affects methylationISORGD:13153166480464Benzo(a)pyrene affects the methylation of EPPIN exonCTDPMID:27901495
EppinRatbenzo[a]pyrene increases methylationISORGD:13153166480464Benzo(a)pyrene results in increased methylation of EPPIN 3' UTRCTDPMID:27901495
EppinRatbenzo[a]pyrene decreases methylationISORGD:13153166480464Benzo(a)pyrene results in decreased methylation of EPPIN promoterCTDPMID:27901495
EppinRatbicalutamide multiple interactionsISORGD:13153176480464FSHB protein inhibits the reaction [bicalutamide results in decreased expression of EPPIN protein]CTDPMID:19587329
EppinRatbicalutamide decreases expressionISORGD:13153176480464bicalutamide results in decreased expression of EPPIN mRNACTDPMID:19587329
EppinRatbisphenol A decreases expressionEXP 6480464bisphenol A results in decreased expression of EPPIN mRNACTDPMID:30816183|PMID:32528016
EppinRatbisphenol A affects expressionEXP 6480464bisphenol A affects the expression of EPPIN mRNACTDPMID:25181051
EppinRatcadmium dichloride decreases expressionISORGD:13153166480464Cadmium Chloride results in decreased expression of EPPIN mRNACTDPMID:26472689
EppinRatcadmium dichloride decreases expressionEXP 6480464Cadmium Chloride results in decreased expression of EPPIN mRNACTDPMID:33453195

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Biological Process
1 to 10 of 10 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
EppinRatdefense response to bacterium involved_inISORGD:13153161624291 PMID:18331357RGDPMID:18331357
EppinRatdefense response to bacterium involved_inIEAUniProtKB:O95925|ensembl:ENSP000003617461600115GO_REF:0000107EnsemblGO_REF:0000107
EppinRatdefense response to bacterium involved_inISSUniProtKB:O959251600115GO_REF:0000024UniProtGO_REF:0000024
EppinRatnegative regulation of calcium ion import involved_inISORGD:13153161624291 PMID:22075473RGDPMID:22075473
EppinRatnegative regulation of calcium ion import involved_inIEAUniProtKB:O95925|ensembl:ENSP000003617461600115GO_REF:0000107EnsemblGO_REF:0000107
EppinRatnegative regulation of flagellated sperm motility involved_inISORGD:13153161624291 PMID:22075473RGDPMID:22075473
EppinRatnegative regulation of flagellated sperm motility involved_inIEAUniProtKB:O95925|ensembl:ENSP000003617461600115GO_REF:0000107EnsemblGO_REF:0000107
EppinRatnegative regulation of flagellated sperm motility involved_inIBAPANTHER:PTN002928860|UniProtKB:O959251600115GO_REF:0000033GO_CentralGO_REF:0000033
EppinRatnegative regulation of peptidase activity involved_inISSUniProtKB:O959251600115GO_REF:0000024UniProtGO_REF:0000024
EppinRatnegative regulation of peptidase activity involved_inISORGD:13153161624291 PMID:18331357RGDPMID:18331357
1 to 10 of 10 rows

Cellular Component
1 to 14 of 14 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
EppinRatacrosomal vesicle located_inISORGD:13153171624291 PMID:12909348RGDPMID:12909348
EppinRatacrosomal vesicle located_inIEAUniProtKB:Q9DA01|ensembl:ENSMUSP000000993891600115GO_REF:0000107EnsemblGO_REF:0000107
EppinRatcell surface located_inISORGD:13153161624291 PMID:17567961RGDPMID:17567961
EppinRatcell surface located_inIEAUniProtKB:O95925|ensembl:ENSP000003617461600115GO_REF:0000107EnsemblGO_REF:0000107
EppinRatcytoplasm located_inISORGD:13153171624291 PMID:12909348RGDPMID:12909348
EppinRatcytoplasm located_inIEAUniProtKB:Q9DA01|ensembl:ENSMUSP000000993891600115GO_REF:0000107EnsemblGO_REF:0000107
EppinRatextracellular region located_inIEAInterPro:IPR0081971600115GO_REF:0000002InterProGO_REF:0000002
EppinRatextracellular region located_inIEAUniProtKB-SubCell:SL-02431600115GO_REF:0000044UniProtGO_REF:0000044
EppinRatextracellular region located_inIEAUniProtKB-KW:KW-09641600115GO_REF:0000043UniProtGO_REF:0000043
EppinRatextracellular space located_inISORGD:13153161624291 PMID:17567961RGDPMID:17567961
EppinRatextracellular space located_inIEAUniProtKB:O95925|ensembl:ENSP000003617461600115GO_REF:0000107EnsemblGO_REF:0000107
EppinRatextracellular space is_active_inIBAPANTHER:PTN002928860|UniProtKB:O959251600115GO_REF:0000033GO_CentralGO_REF:0000033
EppinRatprotein-containing complex part_ofISORGD:13153161624291 PMID:17567961RGDPMID:17567961
EppinRatprotein-containing complex part_ofIEAUniProtKB:O95925|ensembl:ENSP000003617461600115GO_REF:0000107EnsemblGO_REF:0000107
1 to 14 of 14 rows

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
EppinRatpeptidase inhibitor activity enablesIEAInterPro:IPR0081971600115GO_REF:0000002InterProGO_REF:0000002
EppinRatpeptidase inhibitor activity enablesIEAUniProtKB-KW:KW-06461600115GO_REF:0000043UniProtGO_REF:0000043
EppinRatprotein binding enablesISORGD:13153161624291UniProtKB:P02788|UniProtKB:P04279|UniProtKB:P10909 PMID:15590901, PMID:17567961, PMID:19889947RGDPMID:15590901|PMID:17567961|PMID:19889947
EppinRatserine-type endopeptidase inhibitor activity enablesIEAUniProtKB-KW:KW-07221600115GO_REF:0000043UniProtGO_REF:0000043
EppinRatserine-type endopeptidase inhibitor activity enablesIEAInterPro:IPR002223|InterPro:IPR0368801600115GO_REF:0000002InterProGO_REF:0000002


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:12909348   PMID:17567961   PMID:18331357   PMID:21796715   PMID:22075473   PMID:23070980   PMID:25494938  



Eppin
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83173,731,739 - 173,738,651 (-)NCBIGRCr8
mRatBN7.23153,312,396 - 153,319,310 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3153,312,396 - 153,319,310 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3157,122,394 - 157,129,304 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03165,621,354 - 165,628,265 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03163,364,985 - 163,371,894 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03161,043,761 - 161,050,550 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3161,041,727 - 161,050,557 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03167,222,870 - 167,229,659 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43155,607,326 - 155,614,193 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera3151,921,822 - 151,928,632 (-)NCBICelera
Cytogenetic Map3q42NCBI
EPPIN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382045,540,626 - 45,547,401 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2045,540,626 - 45,547,752 (-)EnsemblGRCh38hg38GRCh38
GRCh372044,169,265 - 44,176,040 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362043,602,679 - 43,609,442 (-)NCBINCBI36Build 36hg18NCBI36
Build 342043,602,680 - 43,608,430NCBI
Celera2040,877,785 - 40,884,548 (-)NCBICelera
Cytogenetic Map20q13.12NCBI
HuRef2040,910,738 - 40,917,538 (-)NCBIHuRef
CHM1_12044,071,829 - 44,078,629 (-)NCBICHM1_1
T2T-CHM13v2.02047,276,483 - 47,283,258 (-)NCBIT2T-CHM13v2.0
Eppin
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392164,430,263 - 164,435,491 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2164,430,263 - 164,435,514 (-)EnsemblGRCm39 Ensembl
GRCm382164,588,343 - 164,593,571 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2164,588,343 - 164,593,594 (-)EnsemblGRCm38mm10GRCm38
MGSCv372164,413,843 - 164,419,071 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362164,279,548 - 164,284,776 (-)NCBIMGSCv36mm8
Celera2170,525,008 - 170,530,236 (-)NCBICelera
Cytogenetic Map2H3NCBI
cM Map285.21NCBI
EPPIN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22151,280,058 - 51,289,699 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12051,273,167 - 51,282,808 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02041,877,561 - 41,884,375 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12042,967,885 - 42,973,479 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2042,967,885 - 42,973,479 (-)Ensemblpanpan1.1panPan2
LOC119865675
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ROS_Cfam_1.02433,510,669 - 33,515,510 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12432,771,769 - 32,776,609 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02432,887,464 - 32,892,305 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02433,431,801 - 33,436,642 (-)NCBIUU_Cfam_GSD_1.0
Eppin
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640191,933,312 - 191,946,245 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365147,387,348 - 7,392,788 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365147,387,348 - 7,392,274 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EPPIN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1218,289,659 - 18,295,622 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl218,290,916 - 18,295,317 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605066,932,070 - 66,936,813 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

.

.
Variants in Eppin
9 total Variants

Predicted Target Of
Summary Value
Count of predictions:48
Count of miRNA genes:47
Interacting mature miRNAs:48
Transcripts:ENSRNOT00000019829
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 39 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
12879876Bw182Body weight QTL 1820.003body mass (VT:0001259)body weight (CMO:0000012)3145925360166177555Rat
2301411Bp320Blood pressure QTL 3200.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3145925360166177555Rat
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
1300113Bp176Blood pressure QTL 1763.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3145956084157309487Rat
12879872Cm97Cardiac mass QTL 970.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3145925360166177555Rat
1598877Bp285Blood pressure QTL 2851.50.03arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3120538241165538241Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3130656562169034231Rat
12879873Cm96Cardiac mass QTL 960.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)3145925360166177555Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
12879874Cm98Cardiac mass QTL 980.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)3145925360166177555Rat

1 to 10 of 39 rows
RH139903  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr83173,737,959 - 173,738,578 (+)Marker Load Pipeline
mRatBN7.23153,318,618 - 153,319,237 (+)MAPPERmRatBN7.2
Rnor_6.03161,049,859 - 161,050,477NCBIRnor6.0
Rnor_5.03167,228,968 - 167,229,586UniSTSRnor5.0
RGSC_v3.43155,613,502 - 155,614,120UniSTSRGSC3.4
Celera3151,927,941 - 151,928,559UniSTS
RH 3.4 Map31420.7UniSTS
Cytogenetic Map3q42UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 10 16 51 55 54 23 25 23 6 126 63 31 23 53 31


RefSeq Transcripts NM_001109457 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH474005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000019829   ⟹   ENSRNOP00000019829
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3153,312,396 - 153,319,310 (-)Ensembl
Rnor_6.0 Ensembl3161,041,727 - 161,050,557 (-)Ensembl
RefSeq Acc Id: NM_001109457   ⟹   NP_001102927
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83173,731,739 - 173,738,651 (-)NCBI
mRatBN7.23153,312,396 - 153,319,310 (-)NCBI
Rnor_6.03161,043,761 - 161,050,550 (-)NCBI
Rnor_5.03167,222,870 - 167,229,659 (-)NCBI
RGSC_v3.43155,607,326 - 155,614,193 (-)RGD
Celera3151,921,822 - 151,928,632 (-)RGD
Sequence:
Protein RefSeqs NP_001102927 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein D4A2Z2 (Get FASTA)   NCBI Sequence Viewer  
  EDL96509 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000019829
  ENSRNOP00000019829.5
RefSeq Acc Id: NP_001102927   ⟸   NM_001109457
- Peptide Label: precursor
- UniProtKB: D4A2Z2 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSRNOP00000019829   ⟸   ENSRNOT00000019829
BPTI/Kunitz inhibitor   WAP

Name Modeler Protein Id AA Range Protein Structure
AF-D4A2Z2-F1-model_v2 AlphaFold D4A2Z2 1-134 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13692658
Promoter ID:EPDNEW_R3183
Type:single initiation site
Name:Eppin_1
Description:epididymal peptidase inhibitor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03161,050,557 - 161,050,617EPDNEW


1 to 29 of 29 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-46846 BioCyc
Ensembl Genes ENSRNOG00000028908 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000019829 ENTREZGENE
  ENSRNOT00000019829.7 UniProtKB/Swiss-Prot
Gene3D-CATH 4.10.410.10 UniProtKB/Swiss-Prot
  4.10.75.10 UniProtKB/Swiss-Prot
InterPro Elafin-like_sf UniProtKB/Swiss-Prot
  Kunitz_BPTI UniProtKB/Swiss-Prot
  Kunitz_BPTI_sf UniProtKB/Swiss-Prot
  Prtase_inh_Kunz-CS UniProtKB/Swiss-Prot
  Serpin_venom_toxin UniProtKB/Swiss-Prot
  WAP_dom UniProtKB/Swiss-Prot
KEGG Report rno:685161 UniProtKB/Swiss-Prot
NCBI Gene 685161 ENTREZGENE
PANTHER EPPIN UniProtKB/Swiss-Prot
  EPPIN UniProtKB/Swiss-Prot
Pfam Kunitz_BPTI UniProtKB/Swiss-Prot
  WAP UniProtKB/Swiss-Prot
PhenoGen Eppin PhenoGen
PRINTS BASICPTASE UniProtKB/Swiss-Prot
PROSITE BPTI_KUNITZ_1 UniProtKB/Swiss-Prot
  BPTI_KUNITZ_2 UniProtKB/Swiss-Prot
  WAP UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000028908 RatGTEx
SMART SM00131 UniProtKB/Swiss-Prot
  WAP UniProtKB/Swiss-Prot
Superfamily-SCOP SSF57256 UniProtKB/Swiss-Prot
  SSF57362 UniProtKB/Swiss-Prot
UniProt D4A2Z2 ENTREZGENE, UniProtKB/Swiss-Prot
1 to 29 of 29 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-10-16 Eppin  epididymal peptidase inhibitor  Spinlw1  serine peptidase inhibitor-like, with Kunitz and WAP domains 1 (eppin)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-18 Spinlw1  serine peptidase inhibitor-like, with Kunitz and WAP domains 1 (eppin)  Spinlw1  serine protease inhibitor-like, with Kunitz and WAP domains 1 (eppin)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-05 Spinlw1  serine protease inhibitor-like, with Kunitz and WAP domains 1 (eppin)  LOC685161  similar to Eppin precursor (Epididymal protease inhibitor) (Serine protease inhibitor-like with Kunitz and WAP domains 1)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-01-09 LOC685161  similar to Eppin precursor (Epididymal protease inhibitor) (Serine protease inhibitor-like with Kunitz and WAP domains 1)  LOC684712  similar to Eppin precursor (Epididymal protease inhibitor) (Serine protease inhibitor-like with Kunitz and WAP domains 1)  Data merged from RGD:1586780 1643240 APPROVED
2006-11-20 LOC685161  similar to Eppin precursor (Epididymal protease inhibitor) (Serine protease inhibitor-like with Kunitz and WAP domains 1)      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC684712  similar to Eppin precursor (Epididymal protease inhibitor) (Serine protease inhibitor-like with Kunitz and WAP domains 1)      Symbol and Name status set to provisional 70820 PROVISIONAL