(-)-epigallocatechin 3-gallate multiple interactions ISO RGD:1353168 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of AURKA mRNA CTD PMID:22079256 (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of AURKA mRNA CTD PMID:25729387 (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE decreases expression EXP 6480464 Topotecan results in decreased expression of AURKA mRNA CTD PMID:25729387 1,1-dichloroethene increases expression ISO RGD:1552819 6480464 vinylidene chloride results in increased expression of AURKA mRNA CTD PMID:26682919 17beta-estradiol increases expression ISO RGD:1552819 6480464 Estradiol results in increased expression of AURKA mRNA CTD PMID:25210133 17beta-estradiol increases expression ISO RGD:1353168 6480464 Estradiol results in increased expression of AURKA mRNA CTD PMID:16474171 more ... 17beta-estradiol multiple interactions ISO RGD:1552819 6480464 ESR1 protein promotes the reaction [Estradiol results in increased expression of AURKA mRNA] CTD PMID:25210133 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO RGD:1552819 6480464 [2 more ... CTD PMID:25510870 2,2',4,4'-Tetrabromodiphenyl ether multiple interactions ISO RGD:1353168 6480464 [2 more ... CTD PMID:30796839 2,2',4,4'-Tetrabromodiphenyl ether increases expression ISO RGD:1353168 6480464 2 more ... CTD PMID:30796839 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO RGD:1552819 6480464 [2 more ... CTD PMID:25510870 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:1353168 6480464 Tetrachlorodibenzodioxin results in decreased expression of AURKA mRNA CTD PMID:21802500 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1552819 6480464 Tetrachlorodibenzodioxin affects the expression of AURKA mRNA CTD PMID:21570461 2,3-dimethoxynaphthalene-1,4-dione increases expression ISO RGD:1353168 6480464 2 more ... CTD PMID:19031421 2,4-dinitrotoluene affects expression EXP 6480464 2, 4-dinitrotoluene affects the expression of AURKA mRNA CTD PMID:21346803 2,6-dinitrotoluene affects expression EXP 6480464 2, 6-dinitrotoluene affects the expression of AURKA mRNA CTD PMID:21346803 2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione multiple interactions ISO RGD:1353168 6480464 [Azacitidine co-treated with Thalidomide] affects the expression of AURKA mRNA CTD PMID:18720364 2-methoxyethanol decreases expression EXP 6480464 methyl cellosolve results in decreased expression of AURKA mRNA CTD PMID:19643169 2-methylcholine affects expression ISO RGD:1353168 6480464 beta-methylcholine affects the expression of AURKA mRNA CTD PMID:21179406 3,3',4,4',5-pentachlorobiphenyl increases expression EXP 6480464 3 more ... CTD PMID:23196670 3-methylcholanthrene increases expression ISO RGD:1552819 6480464 Methylcholanthrene results in increased expression of AURKA mRNA CTD PMID:20713471 4,4'-sulfonyldiphenol increases expression ISO RGD:1353168 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of AURKA mRNA CTD PMID:27685785 4-hydroxyphenyl retinamide increases expression ISO RGD:1552819 6480464 Fenretinide results in increased expression of AURKA mRNA CTD PMID:28973697 4-hydroxyphenyl retinamide decreases expression ISO RGD:1552819 6480464 Fenretinide results in decreased expression of AURKA mRNA CTD PMID:28973697 5-azacytidine multiple interactions ISO RGD:1353168 6480464 [Azacitidine co-treated with Thalidomide] affects the expression of AURKA mRNA CTD PMID:18720364 5-fluorouracil decreases expression ISO RGD:1353168 6480464 Fluorouracil results in decreased expression of AURKA mRNA CTD PMID:15205334 more ... 5-fluorouracil decreases expression ISO RGD:1552819 6480464 Fluorouracil results in decreased expression of AURKA mRNA CTD PMID:19272435 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of AURKA mRNA CTD PMID:24780913 acetylsalicylic acid increases expression ISO RGD:1353168 6480464 Aspirin results in increased expression of AURKA mRNA CTD PMID:11906190 afimoxifene decreases expression ISO RGD:1353168 6480464 afimoxifene results in decreased expression of AURKA mRNA CTD PMID:16514628 afimoxifene decreases response to substance ISO RGD:1353168 6480464 AURKA results in decreased susceptibility to afimoxifene CTD PMID:21233418 aflatoxin B1 affects expression ISO RGD:1353168 6480464 Aflatoxin B1 affects the expression of AURKA protein CTD PMID:20106945 aldehydo-D-glucose increases expression ISO RGD:1552819 6480464 Glucose results in increased expression of AURKA mRNA CTD PMID:17178593 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of AURKA mRNA CTD PMID:16483693 arsane multiple interactions ISO RGD:1353168 6480464 Arsenic results in increased phosphorylation of and results in increased activity of AURKA protein, E2F1 protein affects the reaction [Arsenic results in increased expression of AURKA protein] CTD PMID:23174854 arsane increases expression ISO RGD:1353168 6480464 Arsenic results in increased expression of AURKA mRNA, Arsenic results in increased expression of AURKA protein CTD PMID:23174854 arsenic atom multiple interactions ISO RGD:1353168 6480464 Arsenic results in increased phosphorylation of and results in increased activity of AURKA protein, E2F1 protein affects the reaction [Arsenic results in increased expression of AURKA protein] CTD PMID:23174854 arsenic atom increases expression ISO RGD:1353168 6480464 Arsenic results in increased expression of AURKA mRNA, Arsenic results in increased expression of AURKA protein CTD PMID:23174854 arsenic(3+) multiple interactions ISO RGD:1353168 6480464 Arsenic results in increased phosphorylation of and results in increased activity of AURKA protein, E2F1 protein affects the reaction [Arsenic results in increased expression of AURKA protein] CTD PMID:23174854 arsenic(3+) increases expression ISO RGD:1353168 6480464 Arsenic results in increased expression of AURKA mRNA, Arsenic results in increased expression of AURKA protein CTD PMID:23174854 arsenite(3-) decreases expression ISO RGD:1552819 6480464 arsenite results in decreased expression of AURKA mRNA CTD PMID:18929588 azathioprine decreases expression ISO RGD:1353168 6480464 Azathioprine results in decreased expression of AURKA mRNA CTD PMID:22623647 belinostat decreases expression ISO RGD:1353168 6480464 belinostat results in decreased expression of AURKA mRNA, belinostat results in decreased expression of AURKA protein CTD PMID:19606018 belinostat decreases activity ISO RGD:1353168 6480464 belinostat results in decreased activity of AURKA protein CTD PMID:19606018 benzo[a]pyrene decreases expression ISO RGD:1552819 6480464 Benzo(a)pyrene results in decreased expression of AURKA mRNA CTD PMID:19770486 , PMID:22228805 benzo[a]pyrene decreases expression ISO RGD:1353168 6480464 Benzo(a)pyrene results in decreased expression of AURKA mRNA, Benzo(a)pyrene results in decreased expression of AURKA protein CTD PMID:21632981 more ... benzo[a]pyrene diol epoxide I decreases expression ISO RGD:1353168 6480464 7 more ... CTD PMID:19150397 more ... benzo[b]fluoranthene increases expression ISO RGD:1552819 6480464 benzo(b)fluoranthene results in increased expression of AURKA mRNA CTD PMID:26377693 bis(2-chloroethyl) sulfide decreases expression ISO RGD:1353168 6480464 Mustard Gas results in decreased expression of AURKA mRNA CTD PMID:25102026 bis(2-chloroethyl) sulfide increases expression ISO RGD:1552819 6480464 Mustard Gas results in increased expression of AURKA mRNA CTD PMID:26392148 bis(2-ethylhexyl) phthalate increases expression ISO RGD:1353168 6480464 Diethylhexyl Phthalate results in increased expression of AURKA protein CTD PMID:31163220 bisphenol A increases expression ISO RGD:1353168 6480464 bisphenol A results in increased expression of AURKA mRNA CTD PMID:16474171 more ... bisphenol A decreases expression ISO RGD:1353168 6480464 bisphenol A results in decreased expression of AURKA mRNA CTD PMID:29275510 bisphenol A increases phosphorylation ISO RGD:1353168 6480464 bisphenol A results in increased phosphorylation of AURKA protein CTD PMID:30980863 bisphenol A increases methylation ISO RGD:1552819 6480464 bisphenol A results in increased methylation of AURKA promoter CTD PMID:27312807 bisphenol A multiple interactions ISO RGD:1353168 6480464 bisphenol A inhibits the reaction [Doxorubicin results in increased expression of AURKA mRNA] CTD PMID:26320837 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of AURKA mRNA CTD PMID:25181051 cadmium atom decreases expression ISO RGD:1353168 6480464 Cadmium results in decreased expression of AURKA mRNA CTD PMID:21120746 cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of AURKA mRNA CTD PMID:25993096 calcitriol decreases expression ISO RGD:1353168 6480464 Calcitriol results in decreased expression of AURKA mRNA CTD PMID:21592394 calcitriol multiple interactions ISO RGD:1353168 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of AURKA mRNA CTD PMID:21592394 carbon nanotube increases expression ISO RGD:1552819 6480464 Nanotubes, Carbon analog results in increased expression of AURKA mRNA, Nanotubes, Carbon results in increased expression of AURKA mRNA CTD PMID:25554681 chlorambucil increases expression ISO RGD:1552819 6480464 Chlorambucil results in increased expression of AURKA protein CTD PMID:22025197 chloroprene increases expression ISO RGD:1552819 6480464 Chloroprene results in increased expression of AURKA mRNA CTD PMID:23125180 cisplatin multiple interactions ISO RGD:1353168 6480464 MYC protein promotes the reaction [AURKA protein results in decreased susceptibility to Cisplatin] CTD PMID:20890087 cisplatin decreases expression ISO RGD:1552819 6480464 Cisplatin results in decreased expression of AURKA mRNA CTD PMID:25270620 cisplatin decreases response to substance ISO RGD:1353168 6480464 AURKA protein results in decreased susceptibility to Cisplatin CTD PMID:20890087 cisplatin increases expression ISO RGD:1552819 6480464 Cisplatin results in increased expression of AURKA mRNA CTD PMID:21151649 cobalt dichloride decreases expression ISO RGD:1353168 6480464 cobaltous chloride results in decreased expression of AURKA mRNA CTD PMID:19320972 , PMID:19376846 copper atom multiple interactions ISO RGD:1353168 6480464 [NSC 689534 binds to Copper] which results in decreased expression of AURKA mRNA CTD PMID:20971185 copper(0) multiple interactions ISO RGD:1353168 6480464 [NSC 689534 binds to Copper] which results in decreased expression of AURKA mRNA CTD PMID:20971185 copper(2+) multiple interactions ISO RGD:1353168 6480464 [NSC 689534 binds to Copper] which results in decreased expression of AURKA mRNA CTD PMID:20971185 copper(II) sulfate decreases expression ISO RGD:1353168 6480464 Copper Sulfate results in decreased expression of AURKA mRNA CTD PMID:19549813 coumestrol multiple interactions ISO RGD:1353168 6480464 [Coumestrol co-treated with 2 more ... CTD PMID:18310284 , PMID:19167446 coumestrol increases expression ISO RGD:1353168 6480464 Coumestrol results in increased expression of AURKA mRNA CTD PMID:19167446 CU-O LINKAGE decreases expression ISO RGD:1353168 6480464 cupric oxide results in decreased expression of AURKA mRNA CTD PMID:22077320 curcumin decreases expression ISO RGD:1353168 6480464 Curcumin analog results in decreased expression of AURKA mRNA CTD PMID:26409325 cyclosporin A decreases expression ISO RGD:1353168 6480464 Cyclosporine results in decreased expression of AURKA mRNA CTD PMID:19159671 more ... cyclosporin A increases methylation ISO RGD:1353168 6480464 Cyclosporine results in increased methylation of AURKA promoter CTD PMID:27989131 D-glucose increases expression ISO RGD:1552819 6480464 Glucose results in increased expression of AURKA mRNA CTD PMID:17178593 daunorubicin decreases expression ISO RGD:1353168 6480464 Daunorubicin results in decreased expression of AURKA protein CTD PMID:23872705 diazinon affects expression EXP 6480464 Diazinon affects the expression of AURKA mRNA CTD PMID:22546817 dibenz[a,h]anthracene increases expression ISO RGD:1552819 6480464 1 more ... CTD PMID:26377693 dieldrin affects expression EXP 6480464 Dieldrin affects the expression of AURKA mRNA CTD PMID:22546817 dieldrin increases expression EXP 6480464 Dieldrin results in increased expression of AURKA mRNA CTD PMID:23153324 diethyl maleate decreases expression ISO RGD:1552819 6480464 diethyl maleate results in decreased expression of AURKA mRNA CTD PMID:25270620 diethyl maleate increases expression EXP 6480464 diethyl maleate results in increased expression of AURKA mRNA CTD PMID:21161181 diethylstilbestrol increases expression ISO RGD:1552819 6480464 Diethylstilbestrol results in increased expression of AURKA mRNA CTD PMID:15149470 dioxygen decreases expression ISO RGD:1353168 6480464 Oxygen deficiency results in decreased expression of AURKA mRNA CTD PMID:26516004 dorsomorphin multiple interactions ISO RGD:1353168 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin decreases expression ISO RGD:1353168 6480464 Doxorubicin results in decreased expression of AURKA mRNA CTD PMID:15205334 , PMID:29803840 doxorubicin multiple interactions ISO RGD:1353168 6480464 bisphenol A inhibits the reaction [Doxorubicin results in increased expression of AURKA mRNA] CTD PMID:26320837 doxorubicin increases expression ISO RGD:1353168 6480464 Doxorubicin results in increased expression of AURKA mRNA CTD PMID:26320837 Enterolactone multiple interactions ISO RGD:1353168 6480464 [Coumestrol co-treated with 2, 3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of AURKA mRNA CTD PMID:19167446 ethanol multiple interactions ISO RGD:1552819 6480464 [Carbon Tetrachloride co-treated with Ethanol] results in increased expression of AURKA mRNA CTD PMID:30517762 etoposide decreases expression ISO RGD:1552819 6480464 Etoposide results in decreased expression of AURKA mRNA CTD PMID:25270620 flavonoids decreases expression EXP 6480464 Flavonoids results in decreased expression of AURKA mRNA CTD PMID:18035473 flutamide increases expression EXP 6480464 Flutamide results in increased expression of AURKA mRNA CTD PMID:24793618 folic acid multiple interactions ISO RGD:1353168 6480464 [Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of AURKA mRNA CTD PMID:24657277 formaldehyde decreases expression ISO RGD:1353168 6480464 Formaldehyde results in decreased expression of AURKA mRNA CTD PMID:23649840 fulvestrant decreases expression ISO RGD:1353168 6480464 fulvestrant results in decreased expression of AURKA mRNA CTD PMID:16514628 gamma-tocopherol increases expression ISO RGD:1552819 6480464 Tocopherols results in increased expression of AURKA mRNA CTD PMID:17056531 gefitinib decreases response to substance ISO RGD:1353168 6480464 AURKA results in decreased susceptibility to gefitinib CTD PMID:21216229 gefitinib multiple interactions ISO RGD:1353168 6480464 [AURKA results in increased degradation of NFKBIA protein] which results in decreased susceptibility to Gefitinib, [TP53 protein results in decreased expression of AURKA protein] which results in increased susceptibility to Gefitinib CTD PMID:21216229 genistein increases expression ISO RGD:1353168 6480464 Genistein results in increased expression of AURKA mRNA CTD PMID:16474171 glucose increases expression ISO RGD:1552819 6480464 Glucose results in increased expression of AURKA mRNA CTD PMID:17178593 hydrogen peroxide affects expression ISO RGD:1353168 6480464 Hydrogen Peroxide affects the expression of AURKA mRNA CTD PMID:20044591 lead diacetate increases expression ISO RGD:1552819 6480464 lead acetate results in increased expression of AURKA mRNA CTD PMID:20542052 leflunomide decreases expression ISO RGD:1353168 6480464 leflunomide results in decreased expression of AURKA mRNA CTD PMID:28988120 lucanthone decreases expression ISO RGD:1353168 6480464 Lucanthone results in decreased expression of AURKA mRNA CTD PMID:21148553 melphalan increases expression ISO RGD:1552819 6480464 Melphalan results in increased expression of AURKA protein CTD PMID:22025197 methotrexate decreases expression ISO RGD:1353168 6480464 Methotrexate results in decreased expression of AURKA mRNA CTD PMID:24657277 methotrexate multiple interactions ISO RGD:1353168 6480464 [Folic Acid deficiency co-treated with Methotrexate] results in decreased expression of AURKA mRNA CTD PMID:24657277 methyl isocyanate affects expression ISO RGD:1552819 6480464 methyl isocyanate affects the expression of AURKA mRNA CTD PMID:22223508 methyl methanesulfonate decreases expression ISO RGD:1353168 6480464 Methyl Methanesulfonate results in decreased expression of AURKA mRNA CTD PMID:23649840 methylseleninic acid affects expression ISO RGD:1353168 6480464 methylselenic acid affects the expression of AURKA mRNA CTD PMID:14617803 methylseleninic acid decreases expression ISO RGD:1353168 6480464 methylselenic acid results in decreased expression of AURKA mRNA CTD PMID:12517777 mitomycin C decreases expression ISO RGD:1552819 6480464 Mitomycin results in decreased expression of AURKA mRNA CTD PMID:25270620 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO RGD:1353168 6480464 [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Nocodazole] results in increased expression of and results in increased phosphorylation of AURKA protein, MLN8054 inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Nocodazole] results in increased phosphorylation of AURKA protein] CTD PMID:24976383 N-methyl-N-nitrosourea multiple interactions EXP 6480464 [Estrogens co-treated with Progesterone] inhibits the reaction [Methylnitrosourea results in increased expression of AURKA mRNA] CTD PMID:12124350 N-methyl-N-nitrosourea increases expression EXP 6480464 Methylnitrosourea results in increased expression of AURKA mRNA CTD PMID:12124350 N-nitrosodiethylamine multiple interactions ISO RGD:1552819 6480464 [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of AURKA mRNA more ... CTD PMID:17854601 more ... N-nitrosodiethylamine increases expression ISO RGD:1552819 6480464 Diethylnitrosamine results in increased expression of AURKA mRNA CTD PMID:17854601 , PMID:18506893 naphthalene increases expression ISO RGD:1552819 6480464 naphthalene results in increased expression of AURKA mRNA CTD PMID:18978301 nickel atom increases expression ISO RGD:1353168 6480464 Nickel results in increased expression of AURKA mRNA CTD PMID:19031421 nickel dichloride affects expression EXP 6480464 nickel chloride affects the expression of AURKA mRNA CTD PMID:22546817 nocodazole multiple interactions ISO RGD:1353168 6480464 [benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Nocodazole] results in increased expression of and results in increased phosphorylation of AURKA protein, MLN8054 inhibits the reaction [[benzyloxycarbonylleucyl-leucyl-leucine aldehyde co-treated with Nocodazole] results in increased phosphorylation of AURKA protein] CTD PMID:24976383 O-methyleugenol decreases expression EXP 6480464 methyleugenol results in decreased expression of AURKA mRNA CTD PMID:26011634 ochratoxin A multiple interactions ISO RGD:1552819 6480464 TRP53 gene mutant form promotes the reaction [ochratoxin A results in increased expression of AURKA mRNA] CTD PMID:25636497 ochratoxin A increases expression ISO RGD:1552819 6480464 ochratoxin A results in increased expression of AURKA mRNA CTD PMID:25636497 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of AURKA mRNA CTD PMID:25729387 oxaliplatin decreases expression ISO RGD:1353168 6480464 oxaliplatin results in decreased expression of AURKA mRNA CTD PMID:17762391 ozone multiple interactions ISO RGD:1552819 6480464 [NOTCH3 gene mutant form affects the susceptibility to Ozone] which results in increased expression of AURKA mRNA CTD PMID:25658374 p-chloromercuribenzoic acid decreases expression ISO RGD:1353168 6480464 p-Chloromercuribenzoic Acid results in decreased expression of AURKA mRNA CTD PMID:26272509 p-chloromercuribenzoic acid multiple interactions ISO RGD:1353168 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of AURKA mRNA CTD PMID:27188386 paclitaxel increases expression ISO RGD:1353168 6480464 Paclitaxel results in increased expression of AURKA mRNA CTD PMID:17374387 palbociclib decreases expression ISO RGD:1353168 6480464 palbociclib results in decreased expression of AURKA mRNA CTD PMID:22869556 paracetamol affects expression ISO RGD:1552819 6480464 Acetaminophen affects the expression of AURKA mRNA CTD PMID:17562736 paracetamol decreases expression ISO RGD:1353168 6480464 Acetaminophen results in decreased expression of AURKA mRNA CTD PMID:26690555 , PMID:29067470 paraquat affects expression ISO RGD:1552819 6480464 Paraquat affects the expression of AURKA mRNA CTD PMID:26345256 phenethyl isothiocyanate decreases expression ISO RGD:1353168 6480464 phenethyl isothiocyanate results in decreased expression of AURKA mRNA CTD PMID:26678675 phenobarbital multiple interactions ISO RGD:1552819 6480464 [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of AURKA mRNA, NR1I3 protein affects the reaction [Phenobarbital results in increased expression of AURKA mRNA] CTD PMID:19482888 , PMID:24535843 phenobarbital increases expression ISO RGD:1552819 6480464 Phenobarbital results in increased expression of AURKA mRNA CTD PMID:19482888 more ... phenylmercury acetate decreases expression ISO RGD:1353168 6480464 Phenylmercuric Acetate results in decreased expression of AURKA mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO RGD:1353168 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of AURKA mRNA CTD PMID:27188386 phorbol 13-acetate 12-myristate increases expression ISO RGD:1353168 6480464 Tetradecanoylphorbol Acetate results in increased expression of AURKA mRNA CTD PMID:19031421 pirinixic acid decreases expression ISO RGD:1552819 6480464 pirinixic acid results in decreased expression of AURKA mRNA CTD PMID:17426115 pirinixic acid increases expression ISO RGD:1552819 6480464 pirinixic acid results in increased expression of AURKA mRNA CTD PMID:17950772 , PMID:23811191 pirinixic acid multiple interactions ISO RGD:1552819 6480464 PPARA protein promotes the reaction [pirinixic acid results in increased expression of AURKA mRNA] CTD PMID:17950772 piroxicam decreases expression ISO RGD:1353168 6480464 Piroxicam results in decreased expression of AURKA mRNA CTD PMID:21858171 potassium chromate decreases expression ISO RGD:1353168 6480464 potassium chromate(VI) results in decreased expression of AURKA mRNA CTD PMID:22079256 potassium chromate multiple interactions ISO RGD:1353168 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of AURKA mRNA CTD PMID:22079256 progesterone increases expression ISO RGD:1353168 6480464 Progesterone results in increased expression of AURKA mRNA CTD PMID:16888808 progesterone decreases expression ISO RGD:1353168 6480464 Progesterone results in decreased expression of AURKA mRNA CTD PMID:21795739 progesterone increases expression EXP 6480464 Progesterone results in increased expression of AURKA mRNA CTD PMID:12124350 progesterone multiple interactions EXP 6480464 [Estrogens co-treated with Progesterone] inhibits the reaction [Methylnitrosourea results in increased expression of AURKA mRNA] CTD PMID:12124350 promethazine decreases expression EXP 6480464 Promethazine results in decreased expression of AURKA mRNA CTD PMID:26011634 propiconazole increases expression ISO RGD:1552819 6480464 propiconazole results in increased expression of AURKA mRNA CTD PMID:21278054 pyrimidines affects splicing ISO RGD:1353168 6480464 Pyrimidines affects the splicing of AURKA mRNA CTD PMID:25281741 quercetin decreases expression ISO RGD:1353168 6480464 Quercetin results in decreased expression of AURKA mRNA CTD PMID:21632981 quinazolines affects splicing ISO RGD:1353168 6480464 Quinazolines affects the splicing of AURKA mRNA CTD PMID:25281741 raloxifene decreases expression ISO RGD:1353168 6480464 Raloxifene Hydrochloride results in decreased expression of AURKA mRNA CTD PMID:16514628 resveratrol multiple interactions ISO RGD:1353168 6480464 [Coumestrol co-treated with resveratrol] results in increased expression of AURKA mRNA CTD PMID:19167446 resveratrol increases expression ISO RGD:1353168 6480464 resveratrol results in increased expression of AURKA mRNA CTD PMID:19167446 SB 431542 multiple interactions ISO RGD:1353168 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 silver atom multiple interactions ISO RGD:1353168 6480464 CFL1 mRNA promotes the reaction [Silver results in increased expression of AURKA protein modified form] CTD PMID:28499611 silver atom increases expression ISO RGD:1353168 6480464 Silver results in increased expression of AURKA protein modified form CTD PMID:28499611 silver(0) multiple interactions ISO RGD:1353168 6480464 CFL1 mRNA promotes the reaction [Silver results in increased expression of AURKA protein modified form] CTD PMID:28499611 silver(0) increases expression ISO RGD:1353168 6480464 Silver results in increased expression of AURKA protein modified form CTD PMID:28499611 silver(1+) increases expression ISO RGD:1353168 6480464 Silver results in increased expression of AURKA protein modified form CTD PMID:28499611 silver(1+) multiple interactions ISO RGD:1353168 6480464 CFL1 mRNA promotes the reaction [Silver results in increased expression of AURKA protein modified form] CTD PMID:28499611 silver(1+) nitrate increases expression ISO RGD:1353168 6480464 Silver Nitrate results in increased expression of AURKA protein modified form CTD PMID:28499611 silver(1+) nitrate multiple interactions ISO RGD:1353168 6480464 CFL1 mRNA promotes the reaction [Silver Nitrate results in increased expression of AURKA protein modified form] CTD PMID:28499611 simvastatin decreases expression ISO RGD:1353168 6480464 Simvastatin results in decreased expression of AURKA mRNA CTD PMID:17428261 sodium arsenite decreases expression ISO RGD:1552819 6480464 sodium arsenite results in decreased expression of AURKA mRNA CTD PMID:17998272 sodium arsenite increases expression ISO RGD:1353168 6480464 sodium arsenite results in increased expression of AURKA mRNA CTD PMID:29301061 Soman increases expression EXP 6480464 Soman results in increased expression of AURKA mRNA CTD PMID:19281266 sulindac decreases expression ISO RGD:1353168 6480464 Sulindac results in decreased expression of AURKA mRNA CTD PMID:11906190 sulindac sulfide decreases expression ISO RGD:1353168 6480464 sulindac sulfide results in decreased expression of AURKA mRNA CTD PMID:12734198 tert-butyl hydroperoxide increases expression ISO RGD:1552819 6480464 tert-Butylhydroperoxide results in increased expression of AURKA mRNA CTD PMID:15003993 testosterone multiple interactions ISO RGD:1353168 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of AURKA mRNA CTD PMID:21592394 testosterone decreases expression ISO RGD:1353168 6480464 Testosterone results in decreased expression of AURKA mRNA CTD PMID:21592394 tetrachloromethane multiple interactions ISO RGD:1552819 6480464 [Carbon Tetrachloride co-treated with Ethanol] results in increased expression of AURKA mRNA more ... CTD PMID:16006527 more ... tetrachloromethane increases expression ISO RGD:1552819 6480464 Carbon Tetrachloride results in increased expression of AURKA mRNA CTD PMID:17484886 , PMID:27339419 thalidomide multiple interactions ISO RGD:1353168 6480464 [Azacitidine co-treated with Thalidomide] affects the expression of AURKA mRNA CTD PMID:18720364 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of AURKA mRNA CTD PMID:22659510 more ... titanium dioxide increases expression ISO RGD:1552819 6480464 titanium dioxide results in increased expression of AURKA mRNA CTD PMID:23557971 tocopherol increases expression ISO RGD:1552819 6480464 Tocopherols results in increased expression of AURKA mRNA CTD PMID:17056531 topotecan decreases expression EXP 6480464 Topotecan results in decreased expression of AURKA mRNA CTD PMID:25729387 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of AURKA mRNA CTD PMID:25729387 trichloroethene increases expression ISO RGD:1552819 6480464 Trichloroethylene results in increased expression of AURKA mRNA CTD PMID:25549359 trichostatin A decreases expression ISO RGD:1353168 6480464 trichostatin A results in decreased expression of AURKA mRNA CTD PMID:19606018 trichostatin A affects expression ISO RGD:1353168 6480464 trichostatin A affects the expression of AURKA mRNA CTD PMID:28542535 triclosan decreases expression ISO RGD:1353168 6480464 Triclosan results in decreased expression of AURKA mRNA CTD PMID:30510588 trimellitic anhydride increases expression ISO RGD:1552819 6480464 trimellitic anhydride results in increased expression of AURKA mRNA CTD PMID:19042947 tungsten increases expression ISO RGD:1552819 6480464 Tungsten results in increased expression of AURKA mRNA CTD PMID:30912803 tungsten(4+) increases expression ISO RGD:1552819 6480464 Tungsten results in increased expression of AURKA mRNA CTD PMID:30912803 tunicamycin decreases expression ISO RGD:1353168 6480464 Tunicamycin results in decreased expression of AURKA mRNA CTD PMID:22378314 , PMID:29453283 valproic acid decreases expression ISO RGD:1552819 6480464 Valproic Acid results in decreased expression of AURKA mRNA CTD PMID:21427059 valproic acid decreases expression ISO RGD:1353168 6480464 Valproic Acid results in decreased expression of AURKA mRNA CTD PMID:22083351 more ... vincristine increases response to substance ISO RGD:1353168 6480464 AURKA gene SNP results in increased susceptibility to Vincristine CTD PMID:20864405 vincristine increases expression ISO RGD:1353168 6480464 Vincristine results in increased expression of AURKA mRNA CTD PMID:17374387 zinc atom increases expression ISO RGD:1353168 6480464 Zinc deficiency results in increased expression of AURKA mRNA CTD PMID:22171008 zinc(0) increases expression ISO RGD:1353168 6480464 Zinc deficiency results in increased expression of AURKA mRNA CTD PMID:22171008
Biological Process anterior/posterior axis specification ISO RGD:1552819 1624291 MGI:MGI:3836420 (MGI:MGI:5449118 , PMID:22939930) RGD MGI:MGI:5449118 , PMID:22939930 anterior/posterior axis specification IEA UniProtKB:P97477 , ensembl:ENSMUSP000000289971600115 GO_REF:0000107 Ensembl GO_REF:0000107 cell division IEA UniProtKB-KW:KW-0132 1600115 GO_REF:0000037 UniProt GO_REF:0000037 cell projection organization IEA UniProtKB-KW:KW-0970 1600115 GO_REF:0000037 UniProt GO_REF:0000037 centrosome cycle ISO RGD:1552819 1624291 MGI:MGI:1932915 (MGI:MGI:3697244 , PMID:17060449) RGD MGI:MGI:3697244 , PMID:17060449 centrosome localization ISO RGD:1552819 1624291 (MGI:MGI:5488573, PMID:22832491) RGD MGI:MGI:5488573 , PMID:22832491 centrosome localization IEA UniProtKB:P97477 , ensembl:ENSMUSP000000289971600115 GO_REF:0000107 Ensembl GO_REF:0000107 histone-serine phosphorylation IEA GO:0035174 1600115 GO_REF:0000108 GOC GO_REF:0000108 liver regeneration IEA UniProtKB:O14965 , ensembl:ENSP000002169111600115 GO_REF:0000107 Ensembl GO_REF:0000107 liver regeneration ISO RGD:1353168 1624291 (PMID:19435814) RGD PMID:19435814 meiotic cell cycle ISO RGD:1552819 1624291 (MGI:MGI:4942235, PMID:21274965) RGD MGI:MGI:4942235 , PMID:21274965 meiotic spindle organization ISO RGD:1552819 1624291 (MGI:MGI:3045818, PMID:14695913) RGD MGI:MGI:3045818 , PMID:14695913 microtubule cytoskeleton organization ISO RGD:1552819 1624291 MGI:MGI:1932915 more ... RGD MGI:MGI:4438131 , PMID:19668197 mitotic cell cycle ISO RGD:1552819 1624291 (MGI:MGI:3575445 more ... RGD MGI:MGI:3575445 more ... mitotic centrosome separation ISO RGD:1552819 1624291 MGI:MGI:1932915 more ... RGD MGI:MGI:3697244 more ... mitotic centrosome separation IEA UniProtKB:P97477 , ensembl:ENSMUSP000000289971600115 GO_REF:0000107 Ensembl GO_REF:0000107 mitotic spindle organization ISO RGD:1552819 1624291 MGI:MGI:3826513 more ... RGD MGI:MGI:3822929 more ... mitotic spindle organization IBA MGI:MGI:894678 , PANTHER:PTN000681967 13792537 PMID:21873635 GO_Central mitotic spindle organization IEA UniProtKB:P97477 , ensembl:ENSMUSP000000289971600115 GO_REF:0000107 Ensembl GO_REF:0000107 negative regulation of apoptotic process ISO RGD:1552819 1624291 MGI:MGI:3836420 (MGI:MGI:5449118 , PMID:22939930) RGD MGI:MGI:5449118 , PMID:22939930 negative regulation of apoptotic process IEA UniProtKB:P97477 , ensembl:ENSMUSP000000289971600115 GO_REF:0000107 Ensembl GO_REF:0000107 negative regulation of gene expression ISO RGD:1353168 1624291 (PMID:28218735) RGD PMID:28218735 negative regulation of protein binding ISO RGD:1353168 1624291 (PMID:21820309) RGD PMID:21820309 negative regulation of protein binding IEA UniProtKB:O14965 , ensembl:ENSP000002169111600115 GO_REF:0000107 Ensembl GO_REF:0000107 neuron projection extension ISO RGD:1552819 1624291 MGI:MGI:1919369 more ... RGD MGI:MGI:4438131 , PMID:19668197 neuron projection extension IEA UniProtKB:P97477 , ensembl:ENSMUSP000000289971600115 GO_REF:0000107 Ensembl GO_REF:0000107 peptidyl-serine phosphorylation ISO RGD:1353168 1624291 (PMID:28218735) RGD PMID:28218735 positive regulation of meiotic cell cycle process involved in oocyte maturation ISO RGD:13867865 1624291 (PMID:18614302), (PMID:20662813) RGD PMID:18614302 , PMID:20662813 positive regulation of oocyte maturation ISO RGD:1552819 1624291 (MGI:MGI:3045818, PMID:14695913) RGD MGI:MGI:3045818 , PMID:14695913 positive regulation of oocyte maturation IEA UniProtKB:P97477 , ensembl:ENSMUSP000000289971600115 GO_REF:0000107 Ensembl GO_REF:0000107 positive regulation of proteasomal ubiquitin-dependent protein catabolic process ISO RGD:1552819 1624291 (MGI:MGI:3697244, PMID:17060449) RGD MGI:MGI:3697244 , PMID:17060449 positive regulation of proteasomal ubiquitin-dependent protein catabolic process IEA UniProtKB:P97477 , ensembl:ENSMUSP000000289971600115 GO_REF:0000107 Ensembl GO_REF:0000107 positive regulation of translation ISO RGD:13867865 1624291 (PMID:18614302) RGD PMID:18614302 protein localization to centrosome ISO RGD:1552819 1624291 (MGI:MGI:3697244, PMID:17060449) RGD MGI:MGI:3697244 , PMID:17060449 protein localization to centrosome IEA UniProtKB:P97477 , ensembl:ENSMUSP000000289971600115 GO_REF:0000107 Ensembl GO_REF:0000107 protein phosphorylation IDA 619665 RGD protein phosphorylation ISO RGD:1353168 1624291 (PMID:21600873), (PMID:21820309) RGD PMID:21600873 , PMID:21820309 protein phosphorylation ISO RGD:1552819 1624291 MGI:MGI:101765 (MGI:MGI:3697244 , PMID:17060449) RGD MGI:MGI:3697244 , PMID:17060449 regulation of cytokinesis IBA PANTHER:PTN000681967 , SGD:S000006130 13792537 PMID:21873635 GO_Central regulation of protein stability ISO RGD:1353168 1624291 (PMID:15987997) RGD PMID:15987997 regulation of protein stability IEA UniProtKB:O14965 , ensembl:ENSP000002169111600115 GO_REF:0000107 Ensembl GO_REF:0000107 response to estradiol IEP 1643347 RGD response to wounding IEA UniProtKB:O14965 , ensembl:ENSP000002169111600115 GO_REF:0000107 Ensembl GO_REF:0000107 response to wounding ISO RGD:1353168 1624291 (PMID:19435814) RGD PMID:19435814 spindle assembly involved in female meiosis I ISO RGD:1552819 1624291 (MGI:MGI:4942235, PMID:21274965) RGD MGI:MGI:4942235 , PMID:21274965 spindle assembly involved in female meiosis I IEA UniProtKB:P97477 , ensembl:ENSMUSP000000289971600115 GO_REF:0000107 Ensembl GO_REF:0000107 spindle organization ISO RGD:1353168 1624291 (PMID:21820309) RGD PMID:21820309 Cellular Component axon hillock ISO RGD:1552819 1624291 (MGI:MGI:4438131, PMID:19668197) RGD MGI:MGI:4438131 , PMID:19668197 axon hillock IEA UniProtKB:P97477 , ensembl:ENSMUSP000000289971600115 GO_REF:0000107 Ensembl GO_REF:0000107 centriole IEA UniProtKB-SubCell:SL-0046 1600115 GO_REF:0000039 UniProt GO_REF:0000039 centrosome IDA 619665 RGD centrosome ISO RGD:1353168 1624291 (PMID:17726514), (PMID:21399614), (PMID:21600873), (PMID:23213400), (PMID:25657325) RGD GO_REF:0000052 more ... centrosome ISO RGD:1552819 1624291 (MGI:MGI:3831656, PMID:9245792) RGD MGI:MGI:3831656 , PMID:9245792 chromosome passenger complex IBA FB:FBgn0024227 more ... 13792537 PMID:21873635 GO_Central cilium IEA UniProtKB-KW:KW-0969 1600115 GO_REF:0000037 UniProt GO_REF:0000037 condensed nuclear chromosome, centromeric region IBA FB:FBgn0024227 more ... 13792537 PMID:21873635 GO_Central cytoplasm IEA UniProtKB-KW:KW-0963 1600115 GO_REF:0000037 UniProt GO_REF:0000037 cytosol IEA UniProtKB:O14965 , ensembl:ENSP000002169111600115 GO_REF:0000107 Ensembl GO_REF:0000107 cytosol ISO RGD:1353168 1624291 RGD GO_REF:0000052 germinal vesicle ISO RGD:1552819 1624291 (MGI:MGI:3045818, PMID:14695913) RGD MGI:MGI:3045818 , PMID:14695913 germinal vesicle IEA UniProtKB:P97477 , ensembl:ENSMUSP000000289971600115 GO_REF:0000107 Ensembl GO_REF:0000107 meiotic spindle ISO RGD:1552819 1624291 (MGI:MGI:3045818, PMID:14695913) RGD MGI:MGI:3045818 , PMID:14695913 meiotic spindle IEA UniProtKB:P97477 , ensembl:ENSMUSP000000289971600115 GO_REF:0000107 Ensembl GO_REF:0000107 microtubule cytoskeleton ISO RGD:1353168 1624291 (PMID:19801554) RGD PMID:19801554 microtubule organizing center ISO RGD:1552819 1624291 MGI:MGI:1932915 more ... RGD MGI:MGI:4438131 , PMID:19668197 mitotic spindle ISO RGD:1552819 1624291 (MGI:MGI:3831656, PMID:9245792) RGD MGI:MGI:3831656 , PMID:9245792 mitotic spindle pole ISO RGD:1353168 1624291 (PMID:25657325) RGD PMID:25657325 mitotic spindle pole ISS UniProtKB:O14965 1600115 GO_REF:0000024 UniProt GO_REF:0000024 mitotic spindle pole IEA UniProtKB:O14965 , ensembl:ENSP000002169111600115 GO_REF:0000107 Ensembl GO_REF:0000107 nucleoplasm ISO RGD:1353168 1624291 RGD GO_REF:0000052 nucleus ISO RGD:1353168 1624291 (PMID:20531406) RGD PMID:20531406 perinuclear region of cytoplasm ISO RGD:1353168 1624291 (PMID:20531406) RGD PMID:20531406 perinuclear region of cytoplasm IEA UniProtKB:O14965 , ensembl:ENSP000002169111600115 GO_REF:0000107 Ensembl GO_REF:0000107 pronucleus ISO RGD:1552819 1624291 (MGI:MGI:3045818, PMID:14695913) RGD MGI:MGI:3045818 , PMID:14695913 pronucleus IEA UniProtKB:P97477 , ensembl:ENSMUSP000000289971600115 GO_REF:0000107 Ensembl GO_REF:0000107 spindle IDA 619665 RGD spindle microtubule colocalizes_with ISO RGD:1353168 1624291 (PMID:19801554) RGD PMID:19801554 spindle microtubule IBA PANTHER:PTN000681967 more ... 13792537 PMID:21873635 GO_Central spindle microtubule IEA UniProtKB:O14965 , ensembl:ENSP000002169111600115 GO_REF:0000107 Ensembl GO_REF:0000107 spindle midzone IBA FB:FBgn0024227 more ... 13792537 PMID:21873635 GO_Central spindle pole centrosome ISO RGD:1353168 1624291 (PMID:19801554) RGD PMID:19801554 spindle pole centrosome IBA PANTHER:PTN000681967 more ... 13792537 PMID:21873635 GO_Central spindle pole centrosome IEA UniProtKB:O14965 , ensembl:ENSP000002169111600115 GO_REF:0000107 Ensembl GO_REF:0000107 Molecular Function ATP binding IEA UniProtKB-KW:KW-0067 1600115 GO_REF:0000037 UniProt GO_REF:0000037 ATP binding IEA UniProtKB-KW:KW-0067 1600115 GO_REF:0000038 UniProt GO_REF:0000038 histone serine kinase activity ISO RGD:1552819 1624291 (MGI:MGI:4942235, PMID:21274965) RGD MGI:MGI:4942235 , PMID:21274965 histone serine kinase activity IBA MGI:MGI:107168 more ... 13792537 PMID:21873635 GO_Central histone serine kinase activity IEA UniProtKB:P97477 , ensembl:ENSMUSP000000289971600115 GO_REF:0000107 Ensembl GO_REF:0000107 protein binding ISO RGD:1552819 1624291 UniProtKB:A2APB8 more ... RGD MGI:MGI:3575445 more ... protein binding ISO RGD:1353168 1624291 UniProtKB:A2APB8 more ... RGD PMID:12244051 more ... protein heterodimerization activity ISO RGD:1353168 1624291 UniProtKB:P24522 (PMID:20460379) RGD PMID:20460379 protein heterodimerization activity IEA UniProtKB:O14965 , ensembl:ENSP000002169111600115 GO_REF:0000107 Ensembl GO_REF:0000107 protein kinase activity ISO RGD:1552819 1624291 (MGI:MGI:3831656, PMID:9245792) RGD MGI:MGI:3831656 , PMID:9245792 protein kinase activity ISS UniProtKB:O14965 1600115 GO_REF:0000024 UniProt GO_REF:0000024 protein kinase activity ISO RGD:1353168 1624291 (PMID:14580337), (PMID:19801554), (PMID:21600873) RGD PMID:14580337 more ... protein kinase binding ISO RGD:1353168 1624291 UniProtKB:P53350 (PMID:18615013) RGD PMID:18615013 protein kinase binding IEA UniProtKB:O14965 , ensembl:ENSP000002169111600115 GO_REF:0000107 Ensembl GO_REF:0000107 protein serine/threonine kinase activity IDA 619665 RGD protein serine/threonine kinase activity ISO RGD:1353168 1624291 (PMID:13678582), (PMID:18566290), (PMID:21807936), (PMID:28218735) RGD PMID:13678582 more ... ubiquitin protein ligase binding ISO RGD:1552819 1624291 UniProtKB:Q810L3 (MGI:MGI:3575445 , PMID:15793587) RGD MGI:MGI:3575445 , PMID:15793587 ubiquitin protein ligase binding IEA UniProtKB:P97477 , ensembl:ENSMUSP000000289971600115 GO_REF:0000107 Ensembl GO_REF:0000107
Gene-Chemical Interaction Annotations
