AURKA (aurora kinase A) - Rat Genome Database

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Gene: AURKA (aurora kinase A) Canis lupus familiaris
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Symbol: AURKA
Name: aurora kinase A
RGD ID: 12184828
Description: ENCODES a protein that exhibits histone serine kinase activity (ortholog); protein heterodimerization activity (ortholog); protein kinase activity (ortholog); INVOLVED IN anterior/posterior axis specification (ortholog); centrosome cycle (ortholog); centrosome localization (ortholog); ASSOCIATED WITH Aneuploidy (ortholog); Breast Neoplasms (ortholog); Chromosomal Instability (ortholog); FOUND IN axon hillock (ortholog); centrosome (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: serine/threonine-protein kinase 6
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12441,585,483 - 41,604,875 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2441,585,518 - 41,604,791 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2440,833,209 - 40,852,906 (-)NCBI
ROS_Cfam_1.02442,296,241 - 42,316,154 (-)NCBI
UMICH_Zoey_3.12441,536,239 - 41,555,929 (-)NCBI
UNSW_CanFamBas_1.02441,675,064 - 41,694,968 (-)NCBI
UU_Cfam_GSD_1.02442,333,178 - 42,352,923 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

Genomics

Comparative Map Data
AURKA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12441,585,483 - 41,604,875 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2441,585,518 - 41,604,791 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2440,833,209 - 40,852,906 (-)NCBI
ROS_Cfam_1.02442,296,241 - 42,316,154 (-)NCBI
UMICH_Zoey_3.12441,536,239 - 41,555,929 (-)NCBI
UNSW_CanFamBas_1.02441,675,064 - 41,694,968 (-)NCBI
UU_Cfam_GSD_1.02442,333,178 - 42,352,923 (-)NCBI
AURKA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2056,369,389 - 56,392,337 (-)EnsemblGRCh38hg38GRCh38
GRCh382056,369,390 - 56,392,308 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372054,944,446 - 54,967,271 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362054,377,852 - 54,400,758 (-)NCBINCBI36hg18NCBI36
Celera2051,683,792 - 51,707,784 (-)NCBI
Cytogenetic Map20q13.2NCBI
HuRef2051,729,262 - 51,752,229 (-)NCBIHuRef
CHM1_12054,845,539 - 54,868,444 (-)NCBICHM1_1
Aurka
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392172,198,110 - 172,212,820 (-)NCBIGRCm39mm39
GRCm39 Ensembl2172,198,110 - 172,212,455 (-)Ensembl
GRCm382172,356,190 - 172,370,886 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2172,356,190 - 172,370,535 (-)EnsemblGRCm38mm10GRCm38
MGSCv372172,181,696 - 172,196,006 (-)NCBIGRCm37mm9NCBIm37
MGSCv362172,047,401 - 172,061,711 (-)NCBImm8
Celera2178,315,373 - 178,329,688 (-)NCBICelera
Cytogenetic Map2H3NCBI
cM Map294.84NCBI
Aurka
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23161,128,309 - 161,144,524 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl3161,128,313 - 161,144,390 (-)Ensembl
Rnor_6.03170,364,177 - 170,380,278 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3170,364,181 - 170,378,210 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03176,437,310 - 176,456,036 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43163,270,479 - 163,284,506 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13163,177,671 - 163,190,537 (-)NCBI
Celera3160,328,562 - 160,342,589 (-)NCBICelera
Cytogenetic Map3q42NCBI
Aurka
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554452,831,157 - 2,853,357 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554452,831,073 - 2,853,151 (+)NCBIChiLan1.0ChiLan1.0
AURKA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12053,994,880 - 54,017,381 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2053,994,881 - 54,017,339 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02052,707,757 - 52,730,579 (-)NCBIMhudiblu_PPA_v0panPan3
Aurka
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640183,775,540 - 183,790,540 (+)NCBI
SpeTri2.0NW_004936875295,238 - 310,457 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AURKA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11756,954,838 - 56,972,435 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21764,066,378 - 64,083,673 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AURKA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.127,730,060 - 7,753,167 (+)NCBI
ChlSab1.1 Ensembl27,734,128 - 7,752,395 (+)Ensembl
Vero_WHO_p1.0NW_02366605055,804,778 - 55,827,848 (+)NCBI
Aurka
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624790143,818 - 162,065 (+)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 2 8
Low 3 4 22 6 6 6 6 3 12 10 6
Below cutoff 1 3

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005635197 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038434136 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038434137 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038434138 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038457672 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038457673 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038509303 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038509304 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038509305 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038572642 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038572643 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038572644 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038636915 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038636916 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038636917 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000024 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000269 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000024 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000043303   ⟹   ENSCAFP00000038502
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2441,585,518 - 41,604,791 (-)Ensembl
RefSeq Acc Id: XM_005635197   ⟹   XP_005635254
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12441,585,483 - 41,604,875 (-)NCBI
Dog10K_Boxer_Tasha2440,833,209 - 40,852,906 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038434136   ⟹   XP_038290064
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02442,296,241 - 42,312,659 (-)NCBI
RefSeq Acc Id: XM_038434137   ⟹   XP_038290065
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02442,296,241 - 42,316,154 (-)NCBI
RefSeq Acc Id: XM_038434138   ⟹   XP_038290066
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02442,296,241 - 42,313,802 (-)NCBI
RefSeq Acc Id: XM_038457672   ⟹   XP_038313600
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha2440,833,209 - 40,849,412 (-)NCBI
RefSeq Acc Id: XM_038457673   ⟹   XP_038313601
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha2440,833,209 - 40,850,555 (-)NCBI
RefSeq Acc Id: XM_038509303   ⟹   XP_038365231
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12441,536,239 - 41,552,437 (-)NCBI
RefSeq Acc Id: XM_038509304   ⟹   XP_038365232
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12441,536,239 - 41,555,929 (-)NCBI
RefSeq Acc Id: XM_038509305   ⟹   XP_038365233
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12441,536,239 - 41,553,580 (-)NCBI
RefSeq Acc Id: XM_038572642   ⟹   XP_038428570
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02442,333,178 - 42,349,404 (-)NCBI
RefSeq Acc Id: XM_038572643   ⟹   XP_038428571
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02442,333,178 - 42,352,923 (-)NCBI
RefSeq Acc Id: XM_038572644   ⟹   XP_038428572
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02442,333,178 - 42,350,547 (-)NCBI
RefSeq Acc Id: XM_038636915   ⟹   XP_038492843
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02441,675,064 - 41,691,477 (-)NCBI
RefSeq Acc Id: XM_038636916   ⟹   XP_038492844
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02441,675,064 - 41,694,968 (-)NCBI
RefSeq Acc Id: XM_038636917   ⟹   XP_038492845
RefSeq Status:
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02441,675,064 - 41,692,620 (-)NCBI
Reference Sequences
RefSeq Acc Id: XP_005635254   ⟸   XM_005635197
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSCAFP00000038502   ⟸   ENSCAFT00000043303
RefSeq Acc Id: XP_038365232   ⟸   XM_038509304
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038365233   ⟸   XM_038509305
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038365231   ⟸   XM_038509303
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038492844   ⟸   XM_038636916
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038492845   ⟸   XM_038636917
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038492843   ⟸   XM_038636915
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038290065   ⟸   XM_038434137
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038290066   ⟸   XM_038434138
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038290064   ⟸   XM_038434136
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038313601   ⟸   XM_038457673
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038313600   ⟸   XM_038457672
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038428571   ⟸   XM_038572643
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038428572   ⟸   XM_038572644
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038428570   ⟸   XM_038572642
- Peptide Label: isoform X3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000029331 Ensembl, ENTREZGENE
Ensembl Protein ENSCAFP00000038502 ENTREZGENE
NCBI Gene AURKA ENTREZGENE
VGNC ID VGNC:38311 ENTREZGENE