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Gene: Aurka (aurora kinase A) Mus musculus
Symbol: Aurka
Name: aurora kinase A
RGD ID: 1552819
Description: Exhibits histone serine kinase activity and ubiquitin protein ligase binding activity. Involved in several processes, including microtubule cytoskeleton organization; positive regulation of oocyte maturation; and protein localization to centrosome. Localizes to axon hillock; microtubule cytoskeleton; and nucleus. Is expressed in several structures, including central nervous system; germ cell of gonad; neural retina; node; and orbito-sphenoid. Human ortholog(s) of this gene implicated in colorectal cancer; ovarian cancer; and uterine cancer. Orthologous to human AURKA (aurora kinase A); INTERACTS WITH 1,1-dichloroethene; 17beta-estradiol; 2,2',4,4',5,5'-hexachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI; AIRK1; Ar; ARK-1; Ark1; Au; AU019385; aurora 2; aurora A; aurora family kinase 1; Aurora-A; aurora-related kinase 1; aurora/IPL1-related kinase 1; AW539821; Ayk; Ayk1; I; IA; IAK; IAK1; ipl1- and aurora-related kinase 1; serine/threonine kinase 6; serine/threonine-protein kinase 6; serine/threonine-protein kinase aurora-A; serine/threonine-protein kinase Ayk1; Stk; Stk6
Homo sapiens (human) : AURKA (aurora kinase A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Aurka (aurora kinase A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Aurka (aurora kinase A)
Pan paniscus (bonobo/pygmy chimpanzee) : AURKA (aurora kinase A)
Canis lupus familiaris (dog) : AURKA (aurora kinase A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aurka (aurora kinase A)
Sus scrofa (pig) : AURKA (aurora kinase A)
Chlorocebus sabaeus (African green monkey) : AURKA (aurora kinase A)
Heterocephalus glaber (naked mole-rat) : Aurka (aurora kinase A)
more info ...
Related Pseudogenes: Gm15916   Gm17914   Gm3017  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm392172,198,110 - 172,212,820 (-)NCBI
GRCm382172,356,190 - 172,370,886 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2172,356,190 - 172,370,535 (-)EnsemblGRCm38mm10GRCm38
MGSCv372172,181,696 - 172,196,006 (-)NCBIGRCm37mm9NCBIm37
MGSCv362172,047,401 - 172,061,711 (-)NCBImm8
Celera2178,315,373 - 178,329,688 (-)NCBICelera
Cytogenetic Map2H3NCBI
cM Map294.84NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Aurka
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1552819
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-11-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.