Aurka (aurora kinase A) - Rat Genome Database

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Gene: Aurka (aurora kinase A) Mus musculus
Analyze
Symbol: Aurka
Name: aurora kinase A
RGD ID: 1552819
MGI Page MGI
Description: Enables histone serine kinase activity and ubiquitin protein ligase binding activity. Acts upstream of or within several processes, including microtubule cytoskeleton organization; positive regulation of oocyte maturation; and protein localization to centrosome. Located in axon hillock; microtubule cytoskeleton; and nucleus. Is expressed in several structures, including alimentary system; bone; brain; eye; and genitourinary system. Human ortholog(s) of this gene implicated in colorectal cancer; ovarian cancer; and uterine cancer. Orthologous to human AURKA (aurora kinase A).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI; AIRK1; Ar; ARK-1; Ark1; Au; AU019385; aurora 2; aurora A; aurora family kinase 1; Aurora-A; aurora-related kinase 1; aurora/IPL1-related kinase 1; AW539821; Ayk; Ayk1; I; IA; IAK; IAK1; ipl1- and aurora-related kinase 1; serine/threonine kinase 6; serine/threonine-protein kinase 6; serine/threonine-protein kinase aurora-A; serine/threonine-protein kinase Ayk1; Stk; Stk6
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Gm15916   Gm17914   Gm3017  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392172,198,110 - 172,212,820 (-)NCBIGRCm39mm39
GRCm39 Ensembl2172,198,110 - 172,212,455 (-)Ensembl
GRCm382172,356,190 - 172,370,886 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2172,356,190 - 172,370,535 (-)EnsemblGRCm38mm10GRCm38
MGSCv372172,181,696 - 172,196,006 (-)NCBIGRCm37mm9NCBIm37
MGSCv362172,047,401 - 172,061,711 (-)NCBImm8
Celera2178,315,373 - 178,329,688 (-)NCBICelera
Cytogenetic Map2H3NCBI
cM Map294.84NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,1-dichloroethene  (EXP)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP,ISO)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3-dimethoxynaphthalene-1,4-dione  (ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
2-methoxyethanol  (ISO)
2-methylcholine  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3-methylcholanthrene  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (EXP)
5-azacytidine  (ISO)
5-fluorouracil  (EXP,ISO)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
acetylsalicylic acid  (ISO)
acrolein  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (EXP)
alpha-pinene  (ISO)
ammonium chloride  (ISO)
aristolochic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (EXP)
arsenous acid  (ISO)
azathioprine  (ISO)
azoxystrobin  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (EXP)
bis(2-chloroethyl) sulfide  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbon nanotube  (EXP)
chlorambucil  (EXP)
chloroprene  (EXP)
cisplatin  (EXP,ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
CU-O LINKAGE  (ISO)
curcumin  (ISO)
cyclosporin A  (ISO)
D-glucose  (EXP)
daunorubicin  (ISO)
deguelin  (ISO)
diarsenic trioxide  (ISO)
diazinon  (ISO)
dibenz[a,h]anthracene  (EXP)
dieldrin  (ISO)
diethyl maleate  (EXP,ISO)
diethylstilbestrol  (EXP)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
Echimidine  (ISO)
Enterolactone  (ISO)
ethanol  (EXP)
etoposide  (EXP)
fenpyroximate  (ISO)
fenvalerate  (ISO)
fipronil  (ISO)
flavonoids  (ISO)
flutamide  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
gamma-tocopherol  (EXP)
gefitinib  (ISO)
genistein  (ISO)
glucose  (EXP)
hydrogen peroxide  (ISO)
Lasiocarpine  (ISO)
lead diacetate  (EXP)
leflunomide  (ISO)
lucanthone  (ISO)
melphalan  (EXP)
methotrexate  (ISO)
methyl isocyanate  (EXP)
methyl methanesulfonate  (ISO)
methylseleninic acid  (ISO)
mitomycin C  (EXP)
monocrotaline  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-methyl-N-nitrosourea  (ISO)
N-nitrosodiethylamine  (EXP)
N-Nitrosopyrrolidine  (ISO)
naphthalene  (EXP)
nickel atom  (ISO)
nickel dichloride  (ISO)
nocodazole  (ISO)
O-methyleugenol  (ISO)
ochratoxin A  (EXP)
oxaliplatin  (ISO)
ozone  (EXP,ISO)
p-chloromercuribenzoic acid  (ISO)
paclitaxel  (ISO)
palbociclib  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
PCB138  (EXP)
perfluorononanoic acid  (ISO)
phenethyl isothiocyanate  (ISO)
phenobarbital  (EXP)
phenylmercury acetate  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
pirinixic acid  (EXP)
piroxicam  (ISO)
potassium chromate  (ISO)
progesterone  (ISO)
promethazine  (ISO)
propiconazole  (EXP)
pyrimidines  (ISO)
quercetin  (ISO)
quinazolines  (ISO)
raloxifene  (ISO)
resveratrol  (ISO)
riddelliine  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
silicon dioxide  (EXP)
silver atom  (ISO)
silver(0)  (ISO)
silver(1+) nitrate  (ISO)
simvastatin  (ISO)
sodium arsenite  (EXP,ISO)
Soman  (ISO)
sulforaphane  (ISO)
sulindac  (ISO)
sulindac sulfide  (ISO)
sunitinib  (ISO)
tebufenpyrad  (ISO)
tert-butyl hydroperoxide  (EXP)
testosterone  (ISO)
tetrachloromethane  (EXP)
thalidomide  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
tocopherol  (EXP)
topotecan  (ISO)
trichloroethene  (EXP,ISO)
trichostatin A  (ISO)
triclosan  (ISO)
trimellitic anhydride  (EXP)
tungsten  (EXP)
tunicamycin  (ISO)
valproic acid  (EXP,ISO)
vincristine  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

Additional References at PubMed
PMID:641946   PMID:9205101   PMID:9245792   PMID:9434955   PMID:9514916   PMID:10349636   PMID:10523496   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11413462  
PMID:11544199   PMID:12434334   PMID:12477932   PMID:12520002   PMID:12559175   PMID:12815066   PMID:12881723   PMID:14610273   PMID:14695913   PMID:15209400   PMID:15226823   PMID:15480417  
PMID:15489334   PMID:15782199   PMID:15793587   PMID:15923640   PMID:16141072   PMID:16141073   PMID:16617331   PMID:16772293   PMID:17060449   PMID:17292827   PMID:17967808   PMID:18345035  
PMID:18353803   PMID:18372918   PMID:18677115   PMID:18790738   PMID:18799693   PMID:18801727   PMID:19075002   PMID:19376971   PMID:19435814   PMID:19668197   PMID:20003375   PMID:20444701  
PMID:20643351   PMID:21267068   PMID:21274965   PMID:21440680   PMID:21503901   PMID:21600873   PMID:21873635   PMID:22014574   PMID:22024926   PMID:22306998   PMID:22513362   PMID:22832491  
PMID:22837479   PMID:22862944   PMID:22863010   PMID:22875938   PMID:22939930   PMID:23792191   PMID:23810554   PMID:23993973   PMID:24194600   PMID:24242071   PMID:24273164   PMID:24301385  
PMID:24453338   PMID:24478334   PMID:24574519   PMID:24706806   PMID:24875059   PMID:25084151   PMID:25227280   PMID:25318984   PMID:25533335   PMID:25670627   PMID:26174602   PMID:26410627  
PMID:26569382   PMID:26657772   PMID:26658517   PMID:26880200   PMID:27091106   PMID:27102712   PMID:27152455   PMID:27207661   PMID:27213815   PMID:27624071   PMID:27632389   PMID:27694478  
PMID:27753540   PMID:28359584   PMID:28764929   PMID:28923932   PMID:28935709   PMID:28972102   PMID:29393405   PMID:29632206   PMID:29842884   PMID:30044992   PMID:30104731   PMID:30415701  
PMID:30713094   PMID:31895686   PMID:32098917   PMID:32325033   PMID:32636306   PMID:33147210   PMID:33475699   PMID:33510165   PMID:33754019   PMID:33766930   PMID:33854138   PMID:33901174  
PMID:34059773   PMID:34152366   PMID:34251762   PMID:34497269   PMID:34636397  


Genomics

Comparative Map Data
Aurka
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392172,198,110 - 172,212,820 (-)NCBIGRCm39mm39
GRCm39 Ensembl2172,198,110 - 172,212,455 (-)Ensembl
GRCm382172,356,190 - 172,370,886 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2172,356,190 - 172,370,535 (-)EnsemblGRCm38mm10GRCm38
MGSCv372172,181,696 - 172,196,006 (-)NCBIGRCm37mm9NCBIm37
MGSCv362172,047,401 - 172,061,711 (-)NCBImm8
Celera2178,315,373 - 178,329,688 (-)NCBICelera
Cytogenetic Map2H3NCBI
cM Map294.84NCBI
AURKA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2056,369,389 - 56,392,337 (-)EnsemblGRCh38hg38GRCh38
GRCh382056,369,390 - 56,392,308 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372054,944,446 - 54,967,271 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362054,377,852 - 54,400,758 (-)NCBINCBI36hg18NCBI36
Celera2051,683,792 - 51,707,784 (-)NCBI
Cytogenetic Map20q13.2NCBI
HuRef2051,729,262 - 51,752,229 (-)NCBIHuRef
CHM1_12054,845,539 - 54,868,444 (-)NCBICHM1_1
Aurka
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23161,128,309 - 161,144,524 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl3161,128,313 - 161,144,390 (-)Ensembl
Rnor_6.03170,364,177 - 170,380,278 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3170,364,181 - 170,378,210 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03176,437,310 - 176,456,036 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43163,270,479 - 163,284,506 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13163,177,671 - 163,190,537 (-)NCBI
Celera3160,328,562 - 160,342,589 (-)NCBICelera
Cytogenetic Map3q42NCBI
Aurka
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554452,831,157 - 2,853,357 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554452,831,073 - 2,853,151 (+)NCBIChiLan1.0ChiLan1.0
AURKA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12053,994,880 - 54,017,381 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2053,994,881 - 54,017,339 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02052,707,757 - 52,730,579 (-)NCBIMhudiblu_PPA_v0panPan3
AURKA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12441,585,483 - 41,604,875 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2441,585,518 - 41,604,791 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2440,833,209 - 40,852,906 (-)NCBI
ROS_Cfam_1.02442,296,241 - 42,316,154 (-)NCBI
UMICH_Zoey_3.12441,536,239 - 41,555,929 (-)NCBI
UNSW_CanFamBas_1.02441,675,064 - 41,694,968 (-)NCBI
UU_Cfam_GSD_1.02442,333,178 - 42,352,923 (-)NCBI
Aurka
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640183,775,540 - 183,790,540 (+)NCBI
SpeTri2.0NW_004936875295,238 - 310,457 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AURKA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11756,954,838 - 56,972,435 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21764,066,378 - 64,083,673 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AURKA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.127,730,060 - 7,753,167 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl27,734,128 - 7,752,395 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605055,804,778 - 55,827,848 (+)NCBIVero_WHO_p1.0
Aurka
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624790143,818 - 162,065 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
RH136493  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382172,356,323 - 172,356,525UniSTSGRCm38
MGSCv372172,181,823 - 172,182,025UniSTSGRCm37
Celera2178,315,500 - 178,315,702UniSTS
Cytogenetic Map2H3UniSTS
cM Map2100.0UniSTS
AW539821  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382172,356,740 - 172,356,829UniSTSGRCm38
MGSCv372172,182,240 - 172,182,329UniSTSGRCm37
Celera2178,315,917 - 178,316,006UniSTS
Cytogenetic Map2H3UniSTS
cM Map2100.0UniSTS
Whitehead/MRC_RH21921.81UniSTS
U69106  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382172,356,352 - 172,356,486UniSTSGRCm38
MGSCv372172,181,852 - 172,181,986UniSTSGRCm37
Celera2178,315,529 - 178,315,663UniSTS
Cytogenetic Map2H3UniSTS
cM Map2100.0UniSTS
Whitehead/MRC_RH21921.81UniSTS
Aurka  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2H3UniSTS
cM Map2100.0UniSTS
cM Map2100.0UniSTS
Aurka  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2H3UniSTS
cM Map2100.0UniSTS
Aurka  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2H3UniSTS
Aurka  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2H3UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301677Alcp6_malcohol preference locus 6 (mouse)Not determined2163844614182113224Mouse
1301865Hdlq19_mHDL QTL 19 (mouse)Not determined2145676855179677006Mouse
1301618Bglu1_mblood glucose level 1 (mouse)Not determined2118112449174483070Mouse
1302003Sluc17_msusceptibility to lung cancer 17 (mouse)Not determined2162791700182113224Mouse
1302013Tbbmd3_mtotal body bone mineral density 3 (mouse)Not determined2145355029179355165Mouse
1301783Bhr1_mbronchial hyperresponsiveness 1 (mouse)Not determined2142751556178800659Mouse
1300806Aod4_mautoimmune ovarian dysgenesis 4 (mouse)Not determined2145386799179386921Mouse
1357435Epfq2_mepididymal fat pad weight QTL 2 (mouse)Not determined2162895006178800659Mouse
1558991Tailq4_mtail length QTL 4 (mouse)Not determined2162895006178800659Mouse
1300846Pbwg11_mpostnatal body weight growth 11 (mouse)Not determined2139124680173124809Mouse
1300867Lore2_mloss of righting induced by ethanol 2 (mouse)Not determined2144673941181254801Mouse
1357685Skts13_mskin tumor sucseptibility 13 (mouse)Not determined2168781613172563406Mouse
1300622Cfld1_mcystic fibrosis lung disease 1 (mouse)Not determined2155982127182113224Mouse
1357537Lith12_mlithogenic gene 12 (mouse)Not determined2156354671182113224Mouse
1300676Prdt2_mprion disease incubation time 2 (mouse)Not determined2164873361182113224Mouse
1300688Nidd2k_mNidd2 on KK-A (mouse)Not determined2158236417178800659Mouse
1300751Bdt1_mbone density traits 1 (mouse)Not determined2150146982182113224Mouse
1301019Bmd6_mbone mineral density 6 (mouse)Not determined2151936377182113224Mouse
1301348Alcp5_malcohol preference locus 5 (mouse)Not determined2163844614182113224Mouse
1301085Lrnx10_mlearning-contextual 10 (mouse)Not determined2150370301182113224Mouse
1558917Gct8_mgranulosa cell tumorigenesis 8 (mouse)Not determined2149394987182113224Mouse
4142211Nilac3_mnicotine induced locomotor activity 3 (mouse)Not determined2148822973182113224Mouse
5491196Mobq6_mmultigenic obesity QTL 6 (mouse)Not determined285893925181254801Mouse
4142450Lmr16_mleishmaniasis resistance 16 (mouse)Not determined2150370301182113224Mouse
12801456Intmrm1_mintima/media ratio modifier 1 (mouse)2142586427176586530Mouse
11038701Ltpr2e_mLeishmania tropica response 2e (mouse)2150370301182113224Mouse
12790983Bwq12_mbody weight QTL 12 (mouse)2148396284182113224Mouse
12910811Pwbwq3_mpre-weaning body weight QTL 3 (mouse)2169952882179278998Mouse
12910520Scgq3_mspontaneous crescentic glomerulonephritis QTL 3 (mouse)2151867353174547331Mouse
14747002Mancz3_mmandible centroid size 3 (mouse)2152487900182113224Mouse
12801461Intim1_mintima modifier 1 (mouse)2142586427176586530Mouse
11353826Bdln10_mbody length 10 (mouse)2140599562174599562Mouse
11341717Rvfs1_mRift Valley fever susceptibility 1 (mouse)2135590624173607823Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1027
Count of miRNA genes:397
Interacting mature miRNAs:445
Transcripts:ENSMUST00000028997, ENSMUST00000109139, ENSMUST00000109140, ENSMUST00000126107, ENSMUST00000128004
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001291185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_011497 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006499075 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF007817 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK077513 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK085861 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK145968 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169363 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK179444 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK188905 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK189850 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL833787 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL844162 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY336976 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC005425 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC014711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD560646 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466551 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U69106 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U80932 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000028997   ⟹   ENSMUSP00000028997
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2172,198,116 - 172,212,426 (-)Ensembl
GRCm38.p6 Ensembl2172,356,196 - 172,370,506 (-)Ensembl
RefSeq Acc Id: ENSMUST00000109139   ⟹   ENSMUSP00000104767
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2172,198,116 - 172,212,426 (-)Ensembl
GRCm38.p6 Ensembl2172,356,196 - 172,370,506 (-)Ensembl
RefSeq Acc Id: ENSMUST00000109140   ⟹   ENSMUSP00000104768
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2172,198,110 - 172,212,455 (-)Ensembl
GRCm38.p6 Ensembl2172,356,190 - 172,370,535 (-)Ensembl
RefSeq Acc Id: ENSMUST00000126107
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2172,208,469 - 172,212,441 (-)Ensembl
GRCm38.p6 Ensembl2172,366,549 - 172,370,521 (-)Ensembl
RefSeq Acc Id: ENSMUST00000128004
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2172,199,086 - 172,205,051 (-)Ensembl
GRCm38.p6 Ensembl2172,357,166 - 172,363,131 (-)Ensembl
RefSeq Acc Id: NM_001291185   ⟹   NP_001278114
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392172,198,110 - 172,212,490 (-)NCBI
GRCm382172,356,190 - 172,370,570 (-)NCBI
Celera2178,315,367 - 178,329,752 (-)NCBI
Sequence:
RefSeq Acc Id: NM_011497   ⟹   NP_035627
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392172,198,110 - 172,212,490 (-)NCBI
GRCm382172,356,190 - 172,370,570 (-)NCBI
MGSCv372172,181,696 - 172,196,006 (-)RGD
Celera2178,315,367 - 178,329,752 (-)NCBI
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006499075   ⟹   XP_006499138
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392172,198,116 - 172,212,820 (-)NCBI
GRCm382172,356,196 - 172,370,886 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_035627   ⟸   NM_011497
- Peptide Label: isoform a
- UniProtKB: P97477 (UniProtKB/Swiss-Prot),   Q3TEY6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006499138   ⟸   XM_006499075
- Peptide Label: isoform X1
- UniProtKB: P97477 (UniProtKB/Swiss-Prot),   Q3TEY6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001278114   ⟸   NM_001291185
- Peptide Label: isoform b
- UniProtKB: P97477 (UniProtKB/Swiss-Prot),   Q3TEY6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000028997   ⟸   ENSMUST00000028997
RefSeq Acc Id: ENSMUSP00000104767   ⟸   ENSMUST00000109139
RefSeq Acc Id: ENSMUSP00000104768   ⟸   ENSMUST00000109140
Protein Domains
Protein kinase

Promoters
RGD ID:6830855
Promoter ID:MM_KWN:33236
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000116375,   NM_011497,   OTTMUST00000038655,   OTTMUST00000038659,   OTTMUST00000038661,   UC008OCP.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv362172,195,171 - 172,196,967 (-)MPROMDB
RGD ID:6879888
Promoter ID:EPDNEW_M3395
Type:multiple initiation site
Name:Aurka_1
Description:Mus musculus aurora kinase A , transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm382172,370,521 - 172,370,581EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:894678 AgrOrtholog
Ensembl Genes ENSMUSG00000027496 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000028997 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000104767 UniProtKB/Swiss-Prot
  ENSMUSP00000104768 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000028997 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000109139 UniProtKB/Swiss-Prot
  ENSMUST00000109140 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro Aur UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:20878 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:894678 ENTREZGENE
NCBI Gene 20878 ENTREZGENE
PANTHER PTHR24350 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Aurka PhenoGen
PROSITE PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART S_TKc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt AURKA_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3TEY6 ENTREZGENE, UniProtKB/TrEMBL
  Q7TNK2_MOUSE UniProtKB/TrEMBL
  Q8BP87_MOUSE UniProtKB/TrEMBL
UniProt Secondary O35624 UniProtKB/Swiss-Prot
  Q8C3H8 UniProtKB/Swiss-Prot
  Q91YU4 UniProtKB/Swiss-Prot