Aurka (aurora kinase A) - Rat Genome Database

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Gene: Aurka (aurora kinase A) Heterocephalus glaber
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Symbol: Aurka
Name: aurora kinase A
RGD ID: 18913218
Description: ENCODES a protein that exhibits molecular function activator activity (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN anterior/posterior axis specification (ortholog); apoptotic process (ortholog); centrosome cycle (ortholog); ASSOCIATED WITH Aneuploidy (ortholog); Breast Neoplasms (ortholog); Chromosomal Instability (ortholog); FOUND IN basolateral plasma membrane (ortholog); centrosome (ortholog); glutamatergic synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Serine/threonine-protein kinase 6
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624790147,149 - 161,344 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624790143,818 - 162,065 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Aurka
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624790147,149 - 161,344 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624790143,818 - 162,065 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
AURKA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382056,369,390 - 56,392,215 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2056,369,389 - 56,392,337 (-)EnsemblGRCh38hg38GRCh38
GRCh372054,944,446 - 54,967,271 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362054,377,852 - 54,400,758 (-)NCBINCBI36Build 36hg18NCBI36
Celera2051,683,792 - 51,707,784 (-)NCBICelera
Cytogenetic Map20q13.2NCBI
HuRef2051,729,262 - 51,752,229 (-)NCBIHuRef
CHM1_12054,845,539 - 54,868,444 (-)NCBICHM1_1
T2T-CHM13v2.02058,146,836 - 58,169,709 (-)NCBIT2T-CHM13v2.0
Aurka
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392172,198,116 - 172,212,825 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2172,198,110 - 172,212,455 (-)EnsemblGRCm39 Ensembl
GRCm382172,356,190 - 172,370,886 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2172,356,190 - 172,370,535 (-)EnsemblGRCm38mm10GRCm38
MGSCv372172,181,696 - 172,196,006 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362172,047,401 - 172,061,711 (-)NCBIMGSCv36mm8
Celera2178,315,373 - 178,329,688 (-)NCBICelera
Cytogenetic Map2H3NCBI
cM Map294.84NCBI
Aurka
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83181,546,742 - 181,562,890 (-)NCBIGRCr8
mRatBN7.23161,128,309 - 161,144,524 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3161,128,313 - 161,144,390 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3164,937,768 - 164,951,932 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03173,436,787 - 173,450,951 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03171,178,603 - 171,192,767 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03170,364,177 - 170,380,278 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3170,364,181 - 170,378,210 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03176,437,310 - 176,456,036 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43163,270,479 - 163,284,506 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13163,177,671 - 163,190,537 (-)NCBI
Celera3160,328,562 - 160,342,589 (-)NCBICelera
Cytogenetic Map3q42NCBI
Aurka
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554452,831,157 - 2,853,357 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554452,831,073 - 2,853,151 (+)NCBIChiLan1.0ChiLan1.0
AURKA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22162,116,577 - 62,139,405 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12062,109,695 - 62,132,523 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02052,707,757 - 52,730,579 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12053,994,880 - 54,017,381 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2053,994,881 - 54,017,339 (-)Ensemblpanpan1.1panPan2
AURKA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12441,585,483 - 41,604,875 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2441,585,518 - 41,604,791 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2440,833,209 - 40,852,906 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02442,296,241 - 42,316,154 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2442,296,229 - 42,315,779 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12441,536,239 - 41,555,929 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02441,675,064 - 41,694,968 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02442,333,178 - 42,352,923 (-)NCBIUU_Cfam_GSD_1.0
Aurka
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640183,775,540 - 183,790,540 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936875295,238 - 310,457 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AURKA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11756,954,838 - 56,972,435 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21764,066,378 - 64,083,673 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AURKA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.127,730,060 - 7,753,167 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl27,734,128 - 7,752,395 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605055,804,778 - 55,827,848 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000026142   ⟹   ENSHGLP00000025913
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_004624790147,149 - 161,344 (+)Ensembl
RefSeq Acc Id: XM_004858232   ⟹   XP_004858289
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624790143,818 - 162,065 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004858289 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB01223 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000025913
GenBank Protein JAN99153 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004858289   ⟸   XM_004858232
- UniProtKB: G5AW12 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000025913   ⟸   ENSHGLT00000026142


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000018440 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000026142 ENTREZGENE
Gene3D-CATH Phosphorylase Kinase, domain 1 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Aur UniProtKB/TrEMBL
  AURKA UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
NCBI Gene Aurka ENTREZGENE
PANTHER PTHR24350 UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt G5AW12 ENTREZGENE, UniProtKB/TrEMBL