Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-demecolcine | increases expression | ISO | RGD:1319938 | 6480464 | Demecolcine results in increased expression of ZMYND8 mRNA | CTD | PMID:23649840 | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | RGD:1319938 | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of ZMYND8 mRNA | CTD | PMID:22079256 | (S)-nicotine | increases expression | ISO | RGD:1319938 | 6480464 | Nicotine results in increased expression of ZMYND8 mRNA | CTD | PMID:16949557 | 1,2-dimethylhydrazine | multiple interactions | ISO | RGD:1553257 | 6480464 | [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ZMYND8 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | increases expression | ISO | RGD:1553257 | 6480464 | Ethinyl Estradiol results in increased expression of ZMYND8 mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | multiple interactions | ISO | RGD:1553257 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ZMYND8 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:1553257 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ZMYND8 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ZMYND8 mRNA | CTD | PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:1553257 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ZMYND8 mRNA | CTD | PMID:25975270 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1319938 | 6480464 | Tetrachlorodibenzodioxin affects the expression of ZMYND8 mRNA | CTD | PMID:22574217 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1553257 | 6480464 | Tetrachlorodibenzodioxin affects the expression of ZMYND8 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:1553257 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ZMYND8 mRNA | CTD | PMID:15328365 | 2-hydroxypropanoic acid | decreases expression | ISO | RGD:1319938 | 6480464 | Lactic Acid results in decreased expression of ZMYND8 mRNA | CTD | PMID:30851411 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | RGD:1319938 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of ZMYND8 mRNA, [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of ZMYND8 mRNA | CTD | PMID:28628672 | 4,4'-diaminodiphenylmethane | increases expression | ISO | RGD:1553257 | 6480464 | 4, 4'-diaminodiphenylmethane results in increased expression of ZMYND8 mRNA | CTD | PMID:18648102 | 4,4'-sulfonyldiphenol | multiple interactions | ISO | RGD:1319938 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of ZMYND8 mRNA | CTD | PMID:28628672 | 4-hydroxyphenyl retinamide | increases expression | ISO | RGD:1553257 | 6480464 | Fenretinide results in increased expression of ZMYND8 mRNA | CTD | PMID:28973697 | 5-fluorouracil | multiple interactions | ISO | RGD:1319938 | 6480464 | TP53 protein affects the reaction [Fluorouracil results in decreased expression of ZMYND8 mRNA] | CTD | PMID:15016801 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of ZMYND8 mRNA | CTD | PMID:24780913 | acrolein | multiple interactions | ISO | RGD:1319938 | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of ZMYND8 mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of ZMYND8 mRNA | CTD | PMID:32699268 | aflatoxin B1 | increases methylation | ISO | RGD:1319938 | 6480464 | Aflatoxin B1 results in increased methylation of ZMYND8 gene | CTD | PMID:27153756 | all-trans-retinoic acid | increases expression | ISO | RGD:1319938 | 6480464 | Tretinoin results in increased expression of ZMYND8 mRNA, Tretinoin results in increased expression of ZMYND8 protein | CTD | PMID:26655721, PMID:33167477 | all-trans-retinoic acid | multiple interactions | ISO | RGD:1319938 | 6480464 | Tretinoin promotes the reaction [ZMYND8 protein binds to DRD2 gene] more ... | CTD | PMID:26655721 | alpha-pinene | multiple interactions | ISO | RGD:1319938 | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of ZMYND8 mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of ZMYND8 mRNA | CTD | PMID:32699268 | arsenite(3-) | multiple interactions | ISO | RGD:1319938 | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to ZMYND8 mRNA] | CTD | PMID:32406909 | arsenous acid | increases expression | ISO | RGD:1319938 | 6480464 | Arsenic Trioxide results in increased expression of ZMYND8 mRNA | CTD | PMID:20458559 | benzo[a]pyrene | decreases expression | ISO | RGD:1553257 | 6480464 | Benzo(a)pyrene results in decreased expression of ZMYND8 mRNA | CTD | PMID:19770486 | benzo[a]pyrene | increases methylation | ISO | RGD:1319938 | 6480464 | Benzo(a)pyrene results in increased methylation of ZMYND8 promoter | CTD | PMID:27901495 | benzo[a]pyrene | multiple interactions | ISO | RGD:1553257 | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of ZMYND8 mRNA | CTD | PMID:27858113 | benzo[a]pyrene diol epoxide I | decreases expression | ISO | RGD:1319938 | 6480464 | 7 more ... | CTD | PMID:19150397, PMID:20018196 | benzo[b]fluoranthene | multiple interactions | ISO | RGD:1553257 | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of ZMYND8 mRNA | CTD | PMID:27858113 | bisphenol A | decreases expression | ISO | RGD:1553257 | 6480464 | bisphenol A results in decreased expression of ZMYND8 mRNA | CTD | PMID:21932408 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of ZMYND8 mRNA | CTD | PMID:30816183, PMID:32528016 | bisphenol A | decreases methylation | ISO | RGD:1553257 | 6480464 | bisphenol A results in decreased methylation of ZMYND8 promoter | CTD | PMID:27312807 | bisphenol A | multiple interactions | ISO | RGD:1319938 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of ZMYND8 mRNA | CTD | PMID:28628672 | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of ZMYND8 gene | CTD | PMID:28505145 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of ZMYND8 mRNA | CTD | PMID:25181051 | bortezomib | decreases expression | ISO | RGD:1319938 | 6480464 | Bortezomib results in decreased expression of ZMYND8 mRNA | CTD | PMID:20977926 | bromobenzene | increases expression | EXP | | 6480464 | bromobenzene results in increased expression of ZMYND8 mRNA | CTD | PMID:32479839 | cadmium atom | multiple interactions | ISO | RGD:1319938 | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of ZMYND8 mRNA | CTD | PMID:35301059 | cadmium dichloride | multiple interactions | ISO | RGD:1319938 | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of ZMYND8 mRNA | CTD | PMID:35301059 | caffeine | affects phosphorylation | ISO | RGD:1319938 | 6480464 | Caffeine affects the phosphorylation of ZMYND8 protein | CTD | PMID:35688186 | calcium silicate | increases expression | ISO | RGD:1553257 | 6480464 | calcium silicate results in increased expression of ZMYND8 mRNA | CTD | PMID:29279043 | carbamazepine | affects expression | ISO | RGD:1319938 | 6480464 | Carbamazepine affects the expression of ZMYND8 mRNA | CTD | PMID:25979313 | carbon nanotube | decreases expression | ISO | RGD:1553257 | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | CGP 52608 | multiple interactions | ISO | RGD:1319938 | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to ZMYND8 gene] | CTD | PMID:28238834 | chrysene | multiple interactions | ISO | RGD:1553257 | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of ZMYND8 mRNA | CTD | PMID:27858113 | cisplatin | decreases expression | ISO | RGD:1319938 | 6480464 | Cisplatin results in decreased expression of ZMYND8 mRNA | CTD | PMID:19561079 | cisplatin | multiple interactions | ISO | RGD:1319938 | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of ZMYND8 mRNA | CTD | PMID:27392435 | cisplatin | increases expression | ISO | RGD:1319938 | 6480464 | Cisplatin results in increased expression of ZMYND8 mRNA | CTD | PMID:27392435 | copper atom | multiple interactions | ISO | RGD:1553257 | 6480464 | [ATP7A gene mutant form results in increased abundance of Copper] which results in increased expression of ZMYND8 mRNA | CTD | PMID:15467011 | copper(0) | multiple interactions | ISO | RGD:1553257 | 6480464 | [ATP7A gene mutant form results in increased abundance of Copper] which results in increased expression of ZMYND8 mRNA | CTD | PMID:15467011 | coumarin | affects phosphorylation | ISO | RGD:1319938 | 6480464 | coumarin affects the phosphorylation of ZMYND8 protein | CTD | PMID:35688186 | cyclosporin A | decreases expression | ISO | RGD:1319938 | 6480464 | Cyclosporine results in decreased expression of ZMYND8 mRNA | CTD | PMID:25562108 | dexamethasone | multiple interactions | ISO | RGD:1319938 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of ZMYND8 mRNA, [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of ZMYND8 mRNA | CTD | PMID:28628672 | diarsenic trioxide | increases expression | ISO | RGD:1319938 | 6480464 | Arsenic Trioxide results in increased expression of ZMYND8 mRNA | CTD | PMID:20458559 | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of ZMYND8 mRNA | CTD | PMID:21266533 | dicrotophos | increases expression | ISO | RGD:1319938 | 6480464 | dicrotophos results in increased expression of ZMYND8 mRNA | CTD | PMID:28302478 | dioxygen | multiple interactions | ISO | RGD:1553257 | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of ZMYND8 mRNA | CTD | PMID:30529165 | doxorubicin | decreases expression | ISO | RGD:1319938 | 6480464 | Doxorubicin results in decreased expression of ZMYND8 mRNA | CTD | PMID:29803840 | enzyme inhibitor | multiple interactions | ISO | RGD:1319938 | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of ZMYND8 protein | CTD | PMID:23301498 | ethanol | affects splicing | ISO | RGD:1553257 | 6480464 | Ethanol affects the splicing of ZMYND8 mRNA | CTD | PMID:30319688 | ethanol | affects expression | ISO | RGD:1553257 | 6480464 | Ethanol affects the expression of ZMYND8 mRNA | CTD | PMID:30319688 | finasteride | increases expression | EXP | | 6480464 | Finasteride results in increased expression of ZMYND8 mRNA | CTD | PMID:24136188 | folic acid | decreases expression | ISO | RGD:1319938 | 6480464 | Folic Acid results in decreased expression of ZMYND8 mRNA | CTD | PMID:21867686 | folic acid | multiple interactions | ISO | RGD:1553257 | 6480464 | [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of ZMYND8 mRNA | CTD | PMID:22206623 | formaldehyde | decreases expression | ISO | RGD:1319938 | 6480464 | Formaldehyde results in decreased expression of ZMYND8 mRNA | CTD | PMID:20655997, PMID:23416264 | gallic acid | decreases expression | ISO | RGD:1319938 | 6480464 | Gallic Acid results in decreased expression of ZMYND8 mRNA | CTD | PMID:34408198 | genistein | increases expression | EXP | | 6480464 | Genistein results in increased expression of ZMYND8 protein | CTD | PMID:24552547 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of ZMYND8 mRNA | CTD | PMID:33387578 | indometacin | multiple interactions | ISO | RGD:1319938 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of ZMYND8 mRNA, [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of ZMYND8 mRNA | CTD | PMID:28628672 | ivermectin | decreases expression | ISO | RGD:1319938 | 6480464 | Ivermectin results in decreased expression of ZMYND8 protein | CTD | PMID:32959892 | ketamine | decreases expression | EXP | | 6480464 | Ketamine results in decreased expression of ZMYND8 mRNA | CTD | PMID:20080153 | leflunomide | increases expression | EXP | | 6480464 | leflunomide results in increased expression of ZMYND8 mRNA | CTD | PMID:24136188 | lipopolysaccharide | decreases methylation | ISO | RGD:1553257 | 6480464 | Lipopolysaccharides results in decreased methylation of ZMYND8 gene | CTD | PMID:21212295 | lithium chloride | decreases expression | ISO | RGD:1319938 | 6480464 | Lithium Chloride results in decreased expression of ZMYND8 mRNA | CTD | PMID:15711924 | methamphetamine | increases expression | ISO | RGD:1553257 | 6480464 | Methamphetamine results in increased expression of ZMYND8 mRNA | CTD | PMID:26307267 | methylmercury chloride | increases expression | ISO | RGD:1319938 | 6480464 | methylmercuric chloride results in increased expression of ZMYND8 mRNA | CTD | PMID:28001369 | nicotine | increases expression | ISO | RGD:1319938 | 6480464 | Nicotine results in increased expression of ZMYND8 mRNA | CTD | PMID:16949557 | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of ZMYND8 mRNA | CTD | PMID:25729387 | ozone | multiple interactions | ISO | RGD:1319938 | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of ZMYND8 mRNA more ... | CTD | PMID:32699268 | panobinostat | multiple interactions | ISO | RGD:1319938 | 6480464 | (+)-JQ1 compound promotes the reaction [panobinostat affects the expression of ZMYND8 mRNA], panobinostat promotes the reaction [(+)-JQ1 compound affects the expression of ZMYND8 mRNA] | CTD | PMID:26733615 | panobinostat | affects expression | ISO | RGD:1319938 | 6480464 | panobinostat affects the expression of ZMYND8 mRNA | CTD | PMID:26733615 | paracetamol | decreases expression | ISO | RGD:1319938 | 6480464 | Acetaminophen results in decreased expression of ZMYND8 mRNA | CTD | PMID:21420995 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of ZMYND8 mRNA | CTD | PMID:33387578 | pentachlorophenol | increases expression | ISO | RGD:1553257 | 6480464 | Pentachlorophenol results in increased expression of ZMYND8 mRNA | CTD | PMID:23892564 | phenobarbital | decreases expression | ISO | RGD:1553257 | 6480464 | Phenobarbital results in decreased expression of ZMYND8 mRNA | CTD | PMID:19270015 | piroxicam | decreases expression | ISO | RGD:1319938 | 6480464 | Piroxicam results in decreased expression of ZMYND8 mRNA | CTD | PMID:21858171 | potassium chromate | decreases expression | ISO | RGD:1319938 | 6480464 | potassium chromate(VI) results in decreased expression of ZMYND8 mRNA | CTD | PMID:22079256 | potassium chromate | multiple interactions | ISO | RGD:1319938 | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of ZMYND8 mRNA | CTD | PMID:22079256 | rac-lactic acid | decreases expression | ISO | RGD:1319938 | 6480464 | Lactic Acid results in decreased expression of ZMYND8 mRNA | CTD | PMID:30851411 | Soman | decreases expression | EXP | | 6480464 | Soman results in decreased expression of ZMYND8 mRNA | CTD | PMID:19281266 | succimer | multiple interactions | ISO | RGD:1553257 | 6480464 | [Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of ZMYND8 mRNA | CTD | PMID:26378955 | tetrachloromethane | affects expression | ISO | RGD:1553257 | 6480464 | Carbon Tetrachloride affects the expression of ZMYND8 mRNA | CTD | PMID:17484886 | tetraphene | multiple interactions | ISO | RGD:1553257 | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of ZMYND8 mRNA | CTD | PMID:27858113 | titanium dioxide | increases expression | ISO | RGD:1553257 | 6480464 | titanium dioxide results in increased expression of ZMYND8 mRNA | CTD | PMID:29264374 | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of ZMYND8 mRNA | CTD | PMID:25729387 | trichostatin A | increases expression | ISO | RGD:1319938 | 6480464 | trichostatin A results in increased expression of ZMYND8 mRNA | CTD | PMID:24935251 | triptonide | decreases expression | ISO | RGD:1553257 | 6480464 | triptonide results in decreased expression of ZMYND8 mRNA | CTD | PMID:33045310 | troglitazone | decreases expression | ISO | RGD:1553257 | 6480464 | troglitazone results in decreased expression of ZMYND8 mRNA | CTD | PMID:28973697 | tungsten | decreases expression | ISO | RGD:1553257 | 6480464 | Tungsten results in decreased expression of ZMYND8 mRNA | CTD | PMID:30912803 | tunicamycin | decreases expression | ISO | RGD:1553257 | 6480464 | Tunicamycin results in decreased expression of ZMYND8 mRNA | CTD | PMID:17127020 | valproic acid | decreases expression | ISO | RGD:1319938 | 6480464 | Valproic Acid results in decreased expression of ZMYND8 mRNA | CTD | PMID:23179753, PMID:28001369 | valproic acid | affects expression | ISO | RGD:1319938 | 6480464 | Valproic Acid affects the expression of ZMYND8 mRNA | CTD | PMID:25979313 | versicolorin A | decreases expression | ISO | RGD:1319938 | 6480464 | versicolorin A results in decreased expression of ZMYND8 mRNA | CTD | PMID:32106047 | vinclozolin | affects expression | EXP | | 6480464 | vinclozolin affects the expression of ZMYND8 mRNA | CTD | PMID:19015723 | vinclozolin | increases expression | EXP | | 6480464 | vinclozolin results in increased expression of ZMYND8 mRNA | CTD | PMID:20566332 | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of ZMYND8 mRNA | CTD | PMID:23034163 | vincristine | increases expression | ISO | RGD:1319938 | 6480464 | Vincristine results in increased expression of ZMYND8 mRNA | CTD | PMID:23649840 | vorinostat | decreases expression | ISO | RGD:1319938 | 6480464 | vorinostat results in decreased expression of ZMYND8 mRNA | CTD | PMID:22083351 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Gene Ontology Annotations Click to see Annotation Detail View
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