Ptprt (protein tyrosine phosphatase, receptor type, T) - Rat Genome Database

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Gene: Ptprt (protein tyrosine phosphatase, receptor type, T) Rattus norvegicus
Analyze
Symbol: Ptprt
Name: protein tyrosine phosphatase, receptor type, T
RGD ID: 1309653
Description: Predicted to enable several functions, including STAT family protein binding activity; alpha-catenin binding activity; and beta-catenin binding activity. Involved in regulation of synapse organization. Is active in glutamatergic synapse and postsynaptic density membrane. Human ortholog(s) of this gene implicated in colorectal cancer and esophagus squamous cell carcinoma. Orthologous to human PTPRT (protein tyrosine phosphatase receptor type T); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC362263; LOC680887; LOC680897; receptor-type tyrosine-protein phosphatase T; similar to protein tyrosine phosphatase, receptor type, T
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23150,189,343 - 151,287,977 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3150,194,859 - 151,288,124 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3154,002,029 - 155,097,905 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.03162,501,480 - 163,596,833 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.03160,241,501 - 161,340,196 (-)NCBIRnor_WKY
Rnor_6.03157,537,192 - 158,328,984 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3157,544,583 - 158,328,881 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03163,757,891 - 164,563,677 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43152,380,772 - 153,172,076 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13152,154,289 - 153,093,067 (-)NCBI
Celera3148,867,063 - 149,656,746 (-)NCBICelera
Cytogenetic Map3q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. PTPRT and PTPRD Deleterious Mutations and Deletion Predict Bevacizumab Resistance in Metastatic Colorectal Cancer Patients. Hsu HC, etal., Cancers (Basel). 2018 Sep 6;10(9). pii: cancers10090314. doi: 10.3390/cancers10090314.
4. Synapse formation regulated by protein tyrosine phosphatase receptor T through interaction with cell adhesion molecules and Fyn. Lim SH, etal., EMBO J. 2009 Nov 18;28(22):3564-78. doi: 10.1038/emboj.2009.289. Epub 2009 Oct 8.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
10. The Functional Variant in the 3'UTR of PTPRT with the Risk of Esophageal Squamous Cell Carcinoma in a Chinese Population. Yao Y, etal., Cell Physiol Biochem. 2015;36(1):306-14. doi: 10.1159/000374073. Epub 2015 May 5.
11. Regulation of paxillin-p130-PI3K-AKT signaling axis by Src and PTPRT impacts colon tumorigenesis. Zhao Y, etal., Oncotarget. 2017 Jul 25;8(30):48782-48793. doi: 10.18632/oncotarget.10654.
12. Identification and functional characterization of paxillin as a target of protein tyrosine phosphatase receptor T. Zhao Y, etal., Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2592-7. doi: 10.1073/pnas.0914884107. Epub 2010 Jan 21.
Additional References at PubMed
PMID:16973135   PMID:17360477   PMID:18644975   PMID:22767509   PMID:23962429   PMID:24846175  


Genomics

Comparative Map Data
Ptprt
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23150,189,343 - 151,287,977 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3150,194,859 - 151,288,124 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3154,002,029 - 155,097,905 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.03162,501,480 - 163,596,833 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.03160,241,501 - 161,340,196 (-)NCBIRnor_WKY
Rnor_6.03157,537,192 - 158,328,984 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3157,544,583 - 158,328,881 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03163,757,891 - 164,563,677 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43152,380,772 - 153,172,076 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13152,154,289 - 153,093,067 (-)NCBI
Celera3148,867,063 - 149,656,746 (-)NCBICelera
Cytogenetic Map3q42NCBI
PTPRT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382042,031,890 - 43,189,906 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl2042,072,752 - 43,189,970 (-)EnsemblGRCh38hg38GRCh38
GRCh372040,701,396 - 41,818,546 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362040,134,806 - 41,251,971 (-)NCBINCBI36Build 36hg18NCBI36
Build 342040,134,806 - 41,251,971NCBI
Celera2037,412,018 - 38,527,269 (-)NCBICelera
Cytogenetic Map20q12-q13.11NCBI
HuRef2037,438,892 - 38,251,263 (-)NCBIHuRef
CHM1_12040,605,787 - 41,722,632 (-)NCBICHM1_1
T2T-CHM13v2.02043,804,657 - 44,923,941 (-)NCBIT2T-CHM13v2.0
Ptprt
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392161,363,908 - 162,503,106 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2161,363,910 - 162,503,067 (-)EnsemblGRCm39 Ensembl
GRCm382161,521,988 - 162,661,147 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2161,521,990 - 162,661,147 (-)EnsemblGRCm38mm10GRCm38
MGSCv372161,353,359 - 162,486,883 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362161,219,064 - 162,352,588 (-)NCBIMGSCv36mm8
Celera2167,464,067 - 168,594,641 (-)NCBICelera
Cytogenetic Map2H2NCBI
cM Map281.91NCBI
Ptprt
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544514,185,732 - 14,952,980 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544514,185,751 - 14,961,000 (+)NCBIChiLan1.0ChiLan1.0
PTPRT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12039,494,674 - 40,317,701 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2039,502,794 - 40,317,701 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02038,399,267 - 39,526,776 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PTPRT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12429,992,957 - 30,764,469 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2430,000,637 - 30,820,835 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2429,632,448 - 30,668,607 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02430,697,308 - 31,823,739 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2430,697,341 - 31,730,741 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12429,966,056 - 30,996,470 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02430,064,525 - 31,108,057 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02430,613,756 - 31,646,408 (-)NCBIUU_Cfam_GSD_1.0
Ptprt
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640178,978,646 - 179,802,109 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365303,555,103 - 4,319,704 (+)EnsemblSpeTri2.0
SpeTri2.0NW_0049365303,555,070 - 4,327,558 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTPRT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1744,714,645 - 45,881,041 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11744,717,539 - 45,880,822 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21749,805,722 - 49,866,203 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PTPRT
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1220,613,352 - 21,720,417 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605069,391,453 - 70,534,508 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ptprt
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479011,062,926 - 12,136,937 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479011,368,745 - 12,144,895 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ptprt
5967 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:688
Count of miRNA genes:281
Interacting mature miRNAs:349
Transcripts:ENSRNOT00000044466
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)394856903159898684Rat
2312659Slep7Serum leptin concentration QTL 70.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)398535255168026850Rat
2312670Bw94Body weight QTL 940.01inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)398535255168026850Rat
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
619618Rf3Renal disease susceptibility QTL 36.50.001urine albumin amount (VT:0002871)urine albumin excretion rate to body weight ratio (CMO:0001270)3107693393152693393Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3112681431157681431Rat
1576306Schws3Schwannoma susceptibility QTL 30.001nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)3118839124163839124Rat
1598877Bp285Blood pressure QTL 2851.50.03arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3120538241165538241Rat
1300159Kidm4Kidney mass QTL 43.83kidney mass (VT:0002707)right kidney wet weight to body weight ratio (CMO:0001953)3121056165157309487Rat
10755461Coatc16Coat color QTL 16coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)3122438700167438700Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3124122556169034231Rat
2303620Vencon4Ventilatory control QTL 43.9respiration trait (VT:0001943)tidal volume (CMO:0000222)3127162703168026850Rat
631673Iddm13Insulin dependent diabetes mellitus QTL 131.30.663blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)3130193298161695983Rat
1578656Vnigr2Vascular neointimal growth QTL 24.2artery morphology trait (VT:0002191)lesioned artery residual lumen area (CMO:0001417)3130656562169034231Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3130656562169034231Rat
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3131635904169034231Rat
2298477Eau4Experimental allergic uveoretinitis QTL 40.0011uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)3137398739169034231Rat
8552952Pigfal13Plasma insulin-like growth factor 1 level QTL 13blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)3138799500169034231Rat
1298068Bp167Blood pressure QTL 1670.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3141074471169034231Rat
1331726Bp208Blood pressure QTL 2083.129arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3141339013162184794Rat
61335Bp20Blood pressure QTL 203arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3141339236155617360Rat
2317883Alcrsp26Alcohol response QTL 261.80.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)3145526770169034231Rat
12879871Am7Aortic mass QTL 70.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)3145925360166177555Rat
12879872Cm97Cardiac mass QTL 970.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3145925360166177555Rat
12879873Cm96Cardiac mass QTL 960.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)3145925360166177555Rat
12879874Cm98Cardiac mass QTL 980.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)3145925360166177555Rat
12879875Kidm64Kidney mass QTL 640.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3145925360166177555Rat
12879876Bw182Body weight QTL 1820.003body mass (VT:0001259)body weight (CMO:0000012)3145925360166177555Rat
2301411Bp320Blood pressure QTL 3200.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3145925360166177555Rat
1300113Bp176Blood pressure QTL 1763.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3145956084157309487Rat
1598854Memor10Memory QTL 102exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)3145956084161299569Rat
8552791Vie2Viral induced encephalitis QTL 24.1brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)3145956084169034231Rat
1578666Vnigr1Vascular neointimal growth QTL 14.6artery morphology trait (VT:0002191)artery lumen area (CMO:0001409)3149040888168026850Rat

Markers in Region
D3Rat236  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23150,610,883 - 150,611,091 (+)MAPPERmRatBN7.2
Rnor_6.03157,953,288 - 157,953,495NCBIRnor6.0
Rnor_5.03164,174,074 - 164,174,281UniSTSRnor5.0
RGSC_v3.43152,802,829 - 152,803,037RGDRGSC3.4
RGSC_v3.43152,802,830 - 152,803,037UniSTSRGSC3.4
RGSC_v3.13152,708,865 - 152,709,073RGD
Celera3149,280,665 - 149,280,872UniSTS
FHH x ACI Map392.4599RGD
FHH x ACI Map392.4599UniSTS
Cytogenetic Map3q42UniSTS
D3Got133  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23150,686,852 - 150,687,133 (+)MAPPERmRatBN7.2
Rnor_6.03158,029,703 - 158,029,983NCBIRnor6.0
Rnor_5.03164,250,283 - 164,250,563UniSTSRnor5.0
RGSC_v3.43152,878,781 - 152,879,062RGDRGSC3.4
RGSC_v3.43152,878,782 - 152,879,062UniSTSRGSC3.4
RGSC_v3.13152,784,817 - 152,785,098RGD
Celera3149,355,961 - 149,356,241UniSTS
RH 2.0 Map3958.3RGD
Cytogenetic Map3q42UniSTS
D3Got138  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23150,979,153 - 150,979,373 (+)MAPPERmRatBN7.2
Rnor_6.03158,319,283 - 158,319,500NCBIRnor6.0
Rnor_5.03164,539,828 - 164,540,045UniSTSRnor5.0
RGSC_v3.43153,162,265 - 153,162,483RGDRGSC3.4
RGSC_v3.43153,162,266 - 153,162,483UniSTSRGSC3.4
RGSC_v3.13153,068,302 - 153,068,519RGD
Celera3149,647,512 - 149,647,729UniSTS
RH 3.4 Map31390.3RGD
RH 3.4 Map31390.3UniSTS
Cytogenetic Map3q42UniSTS
BF394173  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23150,768,118 - 150,768,277 (+)MAPPERmRatBN7.2
Rnor_6.03158,111,335 - 158,111,493NCBIRnor6.0
Rnor_5.03164,331,844 - 164,332,002UniSTSRnor5.0
RGSC_v3.43152,960,002 - 152,960,160UniSTSRGSC3.4
Celera3149,437,185 - 149,437,343UniSTS
RH 3.4 Map31390.4UniSTS
Cytogenetic Map3q42UniSTS
AU048282  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23150,790,129 - 150,790,269 (+)MAPPERmRatBN7.2
Rnor_6.03158,133,295 - 158,133,434NCBIRnor6.0
Rnor_5.03164,353,999 - 164,354,138UniSTSRnor5.0
RGSC_v3.43152,982,294 - 152,982,433UniSTSRGSC3.4
Celera3149,458,747 - 149,458,886UniSTS
Cytogenetic Map3q42UniSTS
AU049385  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23150,820,313 - 150,820,446 (+)MAPPERmRatBN7.2
Rnor_6.03158,163,867 - 158,163,999NCBIRnor6.0
Rnor_5.03164,384,412 - 164,384,544UniSTSRnor5.0
RGSC_v3.43153,043,438 - 153,043,570UniSTSRGSC3.4
Celera3149,488,901 - 149,489,033UniSTS
Cytogenetic Map3q42UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 56
Low 5 15 8 14 8 1 1 18 16 26 5 1
Below cutoff 3 38 19 10 5 10 7 10 14 15 5 7

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001108603 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001402009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591933 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591935 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591936 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591937 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591938 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105525 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105526 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105527 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105528 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105530 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105532 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105533 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105535 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105536 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105537 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105538 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105539 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105540 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH474005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000120 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000044466   ⟹   ENSRNOP00000041324
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3150,194,859 - 151,288,124 (-)Ensembl
Rnor_6.0 Ensembl3157,544,583 - 158,328,881 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000102150   ⟹   ENSRNOP00000091531
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3150,194,859 - 151,288,124 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000102159   ⟹   ENSRNOP00000083869
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3150,194,859 - 151,288,124 (-)Ensembl
RefSeq Acc Id: NM_001108603   ⟹   NP_001102073
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23150,194,859 - 150,988,663 (-)NCBI
Rnor_6.03157,542,706 - 158,328,984 (-)NCBI
Rnor_5.03163,757,891 - 164,563,677 (-)NCBI
RGSC_v3.43152,380,772 - 153,172,076 (-)RGD
Celera3148,867,063 - 149,656,746 (-)RGD
Sequence:
RefSeq Acc Id: XM_039105523   ⟹   XP_038961451
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23150,189,343 - 151,287,977 (-)NCBI
RefSeq Acc Id: XM_039105524   ⟹   XP_038961452
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23150,189,343 - 151,287,977 (-)NCBI
RefSeq Acc Id: XM_039105525   ⟹   XP_038961453
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23150,189,343 - 151,287,977 (-)NCBI
RefSeq Acc Id: XM_039105526   ⟹   XP_038961454
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23150,189,343 - 151,287,977 (-)NCBI
RefSeq Acc Id: XM_039105527   ⟹   XP_038961455
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23150,189,343 - 151,287,977 (-)NCBI
RefSeq Acc Id: XM_039105528   ⟹   XP_038961456
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23150,189,343 - 151,287,977 (-)NCBI
RefSeq Acc Id: XM_039105529   ⟹   XP_038961457
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23150,189,343 - 151,287,977 (-)NCBI
RefSeq Acc Id: XM_039105530   ⟹   XP_038961458
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23150,189,343 - 151,287,977 (-)NCBI
RefSeq Acc Id: XM_039105532   ⟹   XP_038961460
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23150,189,343 - 151,287,977 (-)NCBI
RefSeq Acc Id: XM_039105533   ⟹   XP_038961461
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23150,189,343 - 151,287,977 (-)NCBI
RefSeq Acc Id: XM_039105534   ⟹   XP_038961462
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23150,189,343 - 151,287,977 (-)NCBI
RefSeq Acc Id: XM_039105535   ⟹   XP_038961463
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23150,189,343 - 151,287,977 (-)NCBI
RefSeq Acc Id: XM_039105536   ⟹   XP_038961464
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23150,189,343 - 151,287,977 (-)NCBI
RefSeq Acc Id: XM_039105537   ⟹   XP_038961465
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23150,189,343 - 151,287,977 (-)NCBI
RefSeq Acc Id: XM_039105538   ⟹   XP_038961466
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23150,189,343 - 151,287,977 (-)NCBI
RefSeq Acc Id: XM_039105539   ⟹   XP_038961467
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23150,189,343 - 151,287,977 (-)NCBI
RefSeq Acc Id: XM_039105540   ⟹   XP_038961468
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23150,189,343 - 151,287,977 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_001102073   ⟸   NM_001108603
- Sequence:
RefSeq Acc Id: ENSRNOP00000041324   ⟸   ENSRNOT00000044466
RefSeq Acc Id: XP_038961468   ⟸   XM_039105540
- Peptide Label: isoform X17
RefSeq Acc Id: XP_038961464   ⟸   XM_039105536
- Peptide Label: isoform X13
- UniProtKB: A0A8I6AFL3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038961461   ⟸   XM_039105533
- Peptide Label: isoform X10
RefSeq Acc Id: XP_038961467   ⟸   XM_039105539
- Peptide Label: isoform X16
RefSeq Acc Id: XP_038961466   ⟸   XM_039105538
- Peptide Label: isoform X15
RefSeq Acc Id: XP_038961458   ⟸   XM_039105530
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038961465   ⟸   XM_039105537
- Peptide Label: isoform X14
- UniProtKB: F1LXJ9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038961456   ⟸   XM_039105528
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038961455   ⟸   XM_039105527
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038961452   ⟸   XM_039105524
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038961463   ⟸   XM_039105535
- Peptide Label: isoform X12
RefSeq Acc Id: XP_038961454   ⟸   XM_039105526
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038961453   ⟸   XM_039105525
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038961462   ⟸   XM_039105534
- Peptide Label: isoform X11
RefSeq Acc Id: XP_038961457   ⟸   XM_039105529
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038961460   ⟸   XM_039105532
- Peptide Label: isoform X9
RefSeq Acc Id: XP_038961451   ⟸   XM_039105523
- Peptide Label: isoform X1
RefSeq Acc Id: ENSRNOP00000091531   ⟸   ENSRNOT00000102150
RefSeq Acc Id: ENSRNOP00000083869   ⟸   ENSRNOT00000102159
Protein Domains
Fibronectin type-III   Ig-like   MAM   Tyrosine specific protein phosphatases   Tyrosine-protein phosphatase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LXJ9-F1-model_v2 AlphaFold F1LXJ9 1-1269 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309653 AgrOrtholog
BioCyc Gene G2FUF-46952 BioCyc
Ensembl Genes ENSRNOG00000032656 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000041324 ENTREZGENE
  ENSRNOP00000041324.4 UniProtKB/TrEMBL
  ENSRNOP00000083869 ENTREZGENE
  ENSRNOP00000083869.1 UniProtKB/TrEMBL
  ENSRNOP00000091531 ENTREZGENE
  ENSRNOP00000091531.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000044466 ENTREZGENE
  ENSRNOT00000044466.5 UniProtKB/TrEMBL
  ENSRNOT00000102150 ENTREZGENE
  ENSRNOT00000102150.1 UniProtKB/TrEMBL
  ENSRNOT00000102159 ENTREZGENE
  ENSRNOT00000102159.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.200 UniProtKB/TrEMBL
  2.60.40.10 UniProtKB/TrEMBL
  3.90.190.10 UniProtKB/TrEMBL
InterPro ConA-like_dom UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  FN_III UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  MAM_dom UniProtKB/TrEMBL
  Prot-tyrosine_phosphatase-like UniProtKB/TrEMBL
  Tyr/Dual-specificity_Pase UniProtKB/TrEMBL
  Tyr_Pase_AS UniProtKB/TrEMBL
  Tyr_Pase_cat UniProtKB/TrEMBL
  Tyr_Pase_rcpt/non-rcpt UniProtKB/TrEMBL
KEGG Report rno:362263 UniProtKB/TrEMBL
NCBI Gene 362263 ENTREZGENE
PANTHER PROTEIN-TYROSINE-PHOSPHATASE UniProtKB/TrEMBL
  SUSHI DOMAIN-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
Pfam fn3 UniProtKB/TrEMBL
  MAM UniProtKB/TrEMBL
  Y_phosphatase UniProtKB/TrEMBL
PhenoGen Ptprt PhenoGen
PRINTS MAMDOMAIN UniProtKB/TrEMBL
  PRTYPHPHTASE UniProtKB/TrEMBL
PROSITE FN3 UniProtKB/TrEMBL
  IG_LIKE UniProtKB/TrEMBL
  MAM_1 UniProtKB/TrEMBL
  MAM_2 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_1 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_2 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_PTP UniProtKB/TrEMBL
SMART FN3 UniProtKB/TrEMBL
  MAM UniProtKB/TrEMBL
  PTPc UniProtKB/TrEMBL
  PTPc_motif UniProtKB/TrEMBL
Superfamily-SCOP ConA_like_lec_gl UniProtKB/TrEMBL
  FN_III-like UniProtKB/TrEMBL
  SSF48726 UniProtKB/TrEMBL
  SSF52799 UniProtKB/TrEMBL
UniProt A0A8I5ZW41_RAT UniProtKB/TrEMBL
  A0A8I6AFL3 ENTREZGENE, UniProtKB/TrEMBL
  F1LXJ9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-07-29 Ptprt  protein tyrosine phosphatase, receptor type, T  LOC680887  similar to protein tyrosine phosphatase, receptor type, T  Data Merged 737654 PROVISIONAL
2015-07-29 Ptprt  protein tyrosine phosphatase, receptor type, T  LOC680897  similar to protein tyrosine phosphatase, receptor type, T  Data Merged 737654 PROVISIONAL
2008-04-30 Ptprt  protein tyrosine phosphatase, receptor type, T   Ptprt_predicted  protein tyrosine phosphatase, receptor type, T (predicted)  'predicted' is removed 2292626 APPROVED
2006-11-19 LOC680887  similar to protein tyrosine phosphatase, receptor type, T      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC680897  similar to protein tyrosine phosphatase, receptor type, T      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-01-12 Ptprt_predicted  protein tyrosine phosphatase, receptor type, T (predicted)      Symbol and Name status set to approved 70820 APPROVED