![]()
Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-epigallocatechin 3-gallate | increases expression | ISO | RGD:1316788 | 6480464 | epigallocatechin gallate results in increased expression of CSE1L protein | CTD | PMID:31195006 | 1,2-dimethylhydrazine | multiple interactions | ISO | RGD:1316789 | 6480464 | [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of CSE1L mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | increases expression | ISO | RGD:1316789 | 6480464 | Ethinyl Estradiol results in increased expression of CSE1L mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | multiple interactions | ISO | RGD:1316789 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CSE1L mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | affects expression | ISO | RGD:1316789 | 6480464 | Ethinyl Estradiol affects the expression of CSE1L mRNA | CTD | PMID:17555576 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:1316789 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CSE1L mRNA, [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in increased expression of CSE1L mRNA | CTD | PMID:17942748, PMID:25975270 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1316788 | 6480464 | Tetrachlorodibenzodioxin affects the expression of CSE1L mRNA | CTD | PMID:22574217 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1316789 | 6480464 | Tetrachlorodibenzodioxin affects the expression of CSE1L mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:1316789 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of CSE1L mRNA | CTD | PMID:17942748 | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2, 4-dinitrotoluene affects the expression of CSE1L mRNA | CTD | PMID:21346803 | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2, 6-dinitrotoluene affects the expression of CSE1L mRNA | CTD | PMID:21346803 | 4-amino-2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 4-amino-2, 6-dinitrotoluene affects the expression of CSE1L mRNA | CTD | PMID:21346803 | 5-aza-2'-deoxycytidine | affects expression | ISO | RGD:1316788 | 6480464 | Decitabine affects the expression of CSE1L mRNA | CTD | PMID:23300844 | 5-fluorouracil | multiple interactions | ISO | RGD:1316788 | 6480464 | TP53 protein affects the reaction [Fluorouracil results in decreased expression of CSE1L mRNA] | CTD | PMID:15016801 | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of CSE1L mRNA | CTD | PMID:28959563 | aflatoxin B1 | increases expression | ISO | RGD:1316788 | 6480464 | Aflatoxin B1 results in increased expression of CSE1L mRNA | CTD | PMID:22100608 | aflatoxin B1 | decreases methylation | ISO | RGD:1316788 | 6480464 | Aflatoxin B1 results in decreased methylation of CSE1L gene | CTD | PMID:27153756 | all-trans-retinoic acid | multiple interactions | ISO | RGD:1316788 | 6480464 | Thiophenes analog promotes the reaction [Tretinoin results in decreased expression of CSE1L mRNA] | CTD | PMID:16140955 | all-trans-retinoic acid | decreases expression | ISO | RGD:1316788 | 6480464 | Tretinoin results in decreased expression of CSE1L mRNA | CTD | PMID:16140955 | antirheumatic drug | increases expression | ISO | RGD:1316788 | 6480464 | Antirheumatic Agents results in increased expression of CSE1L mRNA | CTD | PMID:24449571 | Aroclor 1254 | decreases expression | ISO | RGD:1316789 | 6480464 | Chlorodiphenyl 54% Chlorine results in decreased expression of CSE1L mRNA | CTD | PMID:23650126 | arsane | affects methylation | ISO | RGD:1316788 | 6480464 | Arsenic affects the methylation of CSE1L gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | RGD:1316788 | 6480464 | Arsenic affects the methylation of CSE1L gene | CTD | PMID:25304211 | benzo[a]pyrene | increases expression | ISO | RGD:1316789 | 6480464 | Benzoapyrene results in increased expression of CSE1L mRNA | CTD | PMID:22228805 | benzo[a]pyrene | decreases methylation | ISO | RGD:1316788 | 6480464 | Benzoapyrene results in decreased methylation of CSE1L promoter | CTD | PMID:27901495 | benzo[a]pyrene diol epoxide I | decreases expression | ISO | RGD:1316788 | 6480464 | 7 more ... | CTD | PMID:19150397 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of CSE1L mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of CSE1L mRNA | CTD | PMID:30816183 | bisphenol A | affects expression | ISO | RGD:1316788 | 6480464 | bisphenol A affects the expression of CSE1L mRNA | CTD | PMID:30903817 | bisphenol A | decreases expression | ISO | RGD:1316788 | 6480464 | bisphenol A results in decreased expression of CSE1L mRNA | CTD | PMID:29275510 | buspirone | decreases expression | EXP | | 6480464 | Buspirone results in decreased expression of CSE1L mRNA | CTD | PMID:24136188 | calcitriol | multiple interactions | ISO | RGD:1316788 | 6480464 | [Testosterone co-treated with Calcitriol] results in decreased expression of CSE1L mRNA | CTD | PMID:21592394 | calcitriol | decreases expression | ISO | RGD:1316788 | 6480464 | Calcitriol results in decreased expression of CSE1L mRNA | CTD | PMID:12798352, PMID:21592394 | carbon nanotube | increases expression | ISO | RGD:1316789 | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | chlordecone | increases expression | ISO | RGD:1316789 | 6480464 | Chlordecone results in increased expression of CSE1L mRNA | CTD | PMID:29980752 | choline | multiple interactions | ISO | RGD:1316789 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CSE1L gene | CTD | PMID:20938992 | cisplatin | affects expression | ISO | RGD:1316788 | 6480464 | Cisplatin affects the expression of CSE1L mRNA | CTD | PMID:23300844 | copper atom | multiple interactions | ISO | RGD:1316788 | 6480464 | [Disulfiram binds to Copper] which results in decreased expression of CSE1L mRNA, [Thiosemicarbazones binds to Copper] which results in increased expression of CSE1L protein | CTD | PMID:20931265, PMID:24690739 | copper(0) | multiple interactions | ISO | RGD:1316788 | 6480464 | [Disulfiram binds to Copper] which results in decreased expression of CSE1L mRNA, [Thiosemicarbazones binds to Copper] which results in increased expression of CSE1L protein | CTD | PMID:20931265, PMID:24690739 | coumestrol | multiple interactions | ISO | RGD:1316788 | 6480464 | [Coumestrol co-treated with 2 more ... | CTD | PMID:19167446 | coumestrol | increases expression | ISO | RGD:1316788 | 6480464 | Coumestrol results in increased expression of CSE1L mRNA | CTD | PMID:19167446 | crocidolite asbestos | decreases expression | ISO | RGD:1316789 | 6480464 | Asbestos, Crocidolite results in decreased expression of CSE1L mRNA | CTD | PMID:29279043 | cyclosporin A | decreases expression | ISO | RGD:1316788 | 6480464 | Cyclosporine results in decreased expression of CSE1L mRNA | CTD | PMID:20106945 | cyclosporin A | increases expression | ISO | RGD:1316788 | 6480464 | Cyclosporine results in increased expression of CSE1L mRNA | CTD | PMID:25562108 | dicrotophos | decreases expression | ISO | RGD:1316788 | 6480464 | dicrotophos results in decreased expression of CSE1L mRNA | CTD | PMID:28302478 | dieldrin | affects expression | EXP | | 6480464 | Dieldrin affects the expression of CSE1L mRNA | CTD | PMID:22546817 | dioxygen | decreases expression | ISO | RGD:1316788 | 6480464 | Oxygen deficiency results in decreased expression of CSE1L mRNA | CTD | PMID:26516004 | disulfiram | multiple interactions | ISO | RGD:1316788 | 6480464 | [Disulfiram binds to Copper] which results in decreased expression of CSE1L mRNA | CTD | PMID:24690739 | doxorubicin | multiple interactions | ISO | RGD:1316788 | 6480464 | CSE1L protein promotes the reaction [Doxorubicin results in increased expression of TP53 protein] | CTD | PMID:18377724 | doxorubicin | affects expression | ISO | RGD:1316788 | 6480464 | Doxorubicin affects the expression of CSE1L protein | CTD | PMID:29385562 | Enterolactone | multiple interactions | ISO | RGD:1316788 | 6480464 | [Coumestrol co-treated with 2, 3-bis3'-hydroxybenzylbutyrolactone] results in increased expression of CSE1L mRNA | CTD | PMID:19167446 | enzyme inhibitor | multiple interactions | ISO | RGD:1316788 | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of CSE1L protein | CTD | PMID:23301498 | ethanol | affects splicing | ISO | RGD:1316789 | 6480464 | Ethanol affects the splicing of CSE1L mRNA | CTD | PMID:30319688 | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of CSE1L mRNA | CTD | PMID:24136188 | folic acid | multiple interactions | ISO | RGD:1316789 | 6480464 | [1 more ... | CTD | PMID:20938992, PMID:22206623 | folic acid | decreases expression | ISO | RGD:1316789 | 6480464 | Folic Acid results in decreased expression of CSE1L mRNA | CTD | PMID:25629700 | furan | increases methylation | EXP | | 6480464 | furan results in increased methylation of CSE1L gene | CTD | PMID:22079235 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of CSE1L mRNA | CTD | PMID:22061828 | kojic acid | decreases expression | ISO | RGD:1316788 | 6480464 | kojic acid results in decreased expression of CSE1L mRNA | CTD | PMID:16595896 | L-methionine | multiple interactions | ISO | RGD:1316789 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CSE1L gene | CTD | PMID:20938992 | methylmercury chloride | increases expression | ISO | RGD:1316788 | 6480464 | methylmercuric chloride results in increased expression of CSE1L mRNA | CTD | PMID:28001369 | nefazodone | increases expression | EXP | | 6480464 | nefazodone results in increased expression of CSE1L mRNA | CTD | PMID:24136188 | nickel dichloride | affects expression | EXP | | 6480464 | nickel chloride affects the expression of CSE1L mRNA | CTD | PMID:22546817 | p-menthan-3-ol | increases expression | ISO | RGD:1316788 | 6480464 | Menthol results in increased expression of CSE1L mRNA | CTD | PMID:26760959 | pentachlorophenol | decreases expression | ISO | RGD:1316788 | 6480464 | Pentachlorophenol results in decreased expression of CSE1L protein | CTD | PMID:11064002 | pentachlorophenol | increases expression | ISO | RGD:1316789 | 6480464 | Pentachlorophenol results in increased expression of CSE1L mRNA | CTD | PMID:23892564 | pirinixic acid | decreases expression | ISO | RGD:1316789 | 6480464 | pirinixic acid results in decreased expression of CSE1L mRNA | CTD | PMID:18445702 | pirinixic acid | increases expression | ISO | RGD:1316789 | 6480464 | pirinixic acid results in increased expression of CSE1L mRNA | CTD | PMID:23811191 | resveratrol | multiple interactions | ISO | RGD:1316788 | 6480464 | [Coumestrol co-treated with resveratrol] results in increased expression of CSE1L mRNA | CTD | PMID:19167446 | S-butyl-DL-homocysteine (S,R)-sulfoximine | increases expression | EXP | | 6480464 | Buthionine Sulfoximine results in increased expression of CSE1L protein | CTD | PMID:23736079 | silicon dioxide | affects secretion | ISO | RGD:1316788 | 6480464 | Silicon Dioxide analog affects the secretion of CSE1L protein | CTD | PMID:25895662 | sirolimus | decreases expression | ISO | RGD:1316789 | 6480464 | Sirolimus results in decreased expression of CSE1L mRNA | CTD | PMID:11355896 | sunitinib | decreases expression | ISO | RGD:1316788 | 6480464 | Sunitinib results in decreased expression of CSE1L mRNA | CTD | PMID:31533062 | tamoxifen | affects expression | ISO | RGD:1316789 | 6480464 | Tamoxifen affects the expression of CSE1L mRNA | CTD | PMID:17555576 | testosterone | multiple interactions | ISO | RGD:1316788 | 6480464 | [Testosterone co-treated with Calcitriol] results in decreased expression of CSE1L mRNA | CTD | PMID:21592394 | testosterone | decreases expression | ISO | RGD:1316788 | 6480464 | Testosterone results in decreased expression of CSE1L mRNA | CTD | PMID:21592394 | tetrachlorohydroquinone | decreases expression | ISO | RGD:1316788 | 6480464 | 2 more ... | CTD | PMID:11064002 | thiophenes | multiple interactions | ISO | RGD:1316788 | 6480464 | Thiophenes analog promotes the reaction [Tretinoin results in decreased expression of CSE1L mRNA] | CTD | PMID:16140955 | tolcapone | affects binding | EXP | | 6480464 | tolcapone binds to CSE1L protein | CTD | PMID:19783845 | trichostatin A | affects expression | ISO | RGD:1316788 | 6480464 | trichostatin A affects the expression of CSE1L mRNA | CTD | PMID:28542535 | trimellitic anhydride | increases expression | ISO | RGD:1316789 | 6480464 | trimellitic anhydride results in increased expression of CSE1L mRNA | CTD | PMID:19042947 | tunicamycin | decreases expression | ISO | RGD:1316788 | 6480464 | Tunicamycin results in decreased expression of CSE1L mRNA | CTD | PMID:29453283 | ursodeoxycholic acid | affects expression | ISO | RGD:1316788 | 6480464 | Ursodeoxycholic Acid affects the expression of CSE1L mRNA | CTD | PMID:18422935 | valproic acid | affects expression | ISO | RGD:1316789 | 6480464 | Valproic Acid affects the expression of CSE1L mRNA | CTD | PMID:17963808 | |