Gene: Cyp24a1 (cytochrome P450, family 24, subfamily a, polypeptide 1) Rattus norvegicus
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Symbol: Cyp24a1
Name: cytochrome P450, family 24, subfamily a, polypeptide 1
Description: ENCODES a protein that exhibits 25-hydroxycholecalciferol-24-hydroxylase activity; 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity (ortholog); INVOLVED IN vitamin D metabolic process; osteoblast differentiation (ortholog); oxidation-reduction process (ortholog); ASSOCIATED WITH Abortion, Spontaneous (ortholog); Breast Neoplasms (ortholog); hypercalcemia (ortholog); FOUND IN mitochondrion (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2-butan-2-yl-4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-1,2,4-triazol-3-one; 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine; 3-chloropropane-1,2-diol
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial; 24-OHase; 24R-Ohase; 25-hydroxyvitamin D3 24-hydroxylase; 25-hydroxyvitaminD324-hydroxylase; Cyp24; Cytochrom P450 (25-hydroxyvitamin D24-hydroxylase); cytochrome P450 24A1; cytochrome P450, subfamily 24; cytochrome P450-CC24; P450-CC24; vitamin D(3) 24-hydroxylase; VITD12
Orthologs:
Homo sapiens (human) : CYP24A1 (cytochrome P450 family 24 subfamily A member 1)  HGNC  Alliance
Mus musculus (house mouse) : Cyp24a1 (cytochrome P450, family 24, subfamily a, polypeptide 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : LOC102013768 (1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100971976 (1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial)
Canis lupus familiaris (dog) : CYP24A1 (cytochrome P450 family 24 subfamily A member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101957714 (1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial)
Sus scrofa (pig) : CYP24A1 (cytochrome P450, family 24, subfamily A, polypeptide 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03168,097,484 - 168,111,920 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03174,200,349 - 174,214,780 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43161,542,131 - 161,553,801 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13161,445,746 - 161,460,193 (-)NCBI
Celera3157,820,209 - 157,834,648 (-)NCBICelera
Cytogenetic Map3q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model

Annotation    (Toggle Annotation Detail/Summary View)

Disease Annotations
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Gene Ontology Annotations
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References - uncurated
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Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
  
More on Cyp24a1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2462
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE



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