CYP24A1 (cytochrome P450 family 24 subfamily A member 1) - Rat Genome Database

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Gene: CYP24A1 (cytochrome P450 family 24 subfamily A member 1) Pan paniscus
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Symbol: CYP24A1
Name: cytochrome P450 family 24 subfamily A member 1
RGD ID: 11842836
Description: ENCODES a protein that exhibits 25-hydroxycholecalciferol-24-hydroxylase activity (ortholog); vitamin D 24-hydroxylase activity (ortholog); INVOLVED IN cellular response to vitamin D (ortholog); vitamin D metabolic process (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); breast carcinoma (ortholog); Breast Neoplasms (ortholog); FOUND IN mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial; LOC100971976
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22159,906,065 - 59,926,662 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12059,899,186 - 59,919,783 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02050,500,103 - 50,520,487 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12051,721,895 - 51,742,716 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2051,721,685 - 51,742,716 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CYP24A1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22159,906,065 - 59,926,662 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12059,899,186 - 59,919,783 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02050,500,103 - 50,520,487 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12051,721,895 - 51,742,716 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2051,721,685 - 51,742,716 (-)Ensemblpanpan1.1panPan2
CYP24A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382054,143,538 - 54,173,986 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2054,153,446 - 54,173,986 (-)EnsemblGRCh38hg38GRCh38
GRCh372052,769,985 - 52,790,525 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362052,203,395 - 52,223,931 (-)NCBINCBI36Build 36hg18NCBI36
Celera2049,474,643 - 49,495,166 (-)NCBICelera
Cytogenetic Map20q13.2NCBI
HuRef2049,516,544 - 49,537,045 (-)NCBIHuRef
CHM1_12052,673,171 - 52,693,667 (-)NCBICHM1_1
T2T-CHM13v2.02055,917,843 - 55,948,320 (-)NCBIT2T-CHM13v2.0
Cyp24a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392170,324,877 - 170,339,065 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2170,324,628 - 170,339,065 (-)EnsemblGRCm39 Ensembl
GRCm382170,482,957 - 170,497,145 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2170,482,708 - 170,497,145 (-)EnsemblGRCm38mm10GRCm38
MGSCv372170,308,465 - 170,322,638 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362170,174,170 - 170,188,343 (-)NCBIMGSCv36mm8
Celera2176,437,445 - 176,451,588 (-)NCBICelera
Cytogenetic Map2H3NCBI
cM Map291.91NCBI
Cyp24a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83179,694,647 - 179,709,083 (-)NCBIGRCr8
mRatBN7.23159,275,947 - 159,290,383 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3159,275,947 - 159,290,383 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3163,075,289 - 163,089,740 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03171,574,931 - 171,589,382 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03169,316,153 - 169,330,604 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03168,097,484 - 168,111,920 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3168,097,485 - 168,111,920 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03174,200,349 - 174,214,780 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43161,542,131 - 161,553,801 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13161,445,746 - 161,460,193 (-)NCBI
Celera3157,820,209 - 157,834,648 (-)NCBICelera
Cytogenetic Map3q42NCBI
LOC102013768
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554454,873,942 - 4,891,780 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554454,874,583 - 4,891,723 (+)NCBIChiLan1.0ChiLan1.0
CYP24A1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12439,861,018 - 39,878,161 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2439,862,355 - 39,878,216 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2439,106,835 - 39,123,588 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02440,574,274 - 40,591,063 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2440,576,845 - 40,591,462 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12439,809,842 - 39,826,569 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02439,945,173 - 39,961,923 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02440,527,730 - 40,544,495 (-)NCBIUU_Cfam_GSD_1.0
LOC101957714
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640186,013,122 - 186,029,747 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365141,467,261 - 1,480,185 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365141,467,460 - 1,480,185 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CYP24A1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1755,110,590 - 55,130,363 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11755,110,546 - 55,130,328 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21761,891,352 - 61,912,269 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CYP24A1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.129,868,794 - 9,889,510 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl29,868,678 - 9,885,884 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605057,988,669 - 58,009,485 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LOC101716773
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247902,182,598 - 2,200,425 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247902,183,079 - 2,200,219 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000054405   ⟹   ENSPPAP00000031540
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2051,721,685 - 51,742,716 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000054407   ⟹   ENSPPAP00000031542
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2051,721,685 - 51,742,716 (-)Ensembl
RefSeq Acc Id: XM_055104799   ⟹   XP_054960774
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22159,906,065 - 59,926,662 (-)NCBI
NHGRI_mPanPan12059,902,225 - 59,919,373 (-)NCBI
RefSeq Acc Id: XM_055104800   ⟹   XP_054960775
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22159,906,065 - 59,926,662 (-)NCBI
NHGRI_mPanPan12059,902,225 - 59,919,373 (-)NCBI
RefSeq Acc Id: XM_063601018   ⟹   XP_063457088
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22159,906,065 - 59,926,662 (-)NCBI
Protein Sequences
Protein RefSeqs XP_054960774 (Get FASTA)   NCBI Sequence Viewer  
  XP_054960775 (Get FASTA)   NCBI Sequence Viewer  
  XP_063457088 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000031540.1
  ENSPPAP00000031542.1
Ensembl Acc Id: ENSPPAP00000031540   ⟸   ENSPPAT00000054405
Ensembl Acc Id: ENSPPAP00000031542   ⟸   ENSPPAT00000054407
RefSeq Acc Id: XP_054960775   ⟸   XM_055104800
- Peptide Label: isoform X2
- UniProtKB: A0A2R9BYF3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054960774   ⟸   XM_055104799
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BPE7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063457088   ⟸   XM_063601018
- Peptide Label: isoform X2
- UniProtKB: A0A2R9BYF3 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000038708 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000054405.1 UniProtKB/TrEMBL
  ENSPPAT00000054407.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.630.10 UniProtKB/TrEMBL
InterPro CYP11_CYP27_families UniProtKB/TrEMBL
  Cyt_P450 UniProtKB/TrEMBL
  Cyt_P450_CS UniProtKB/TrEMBL
  Cyt_P450_E_CYP24A_mit UniProtKB/TrEMBL
  Cyt_P450_E_grp-I UniProtKB/TrEMBL
  Cyt_P450_sf UniProtKB/TrEMBL
NCBI Gene LOC100971976 ENTREZGENE
PANTHER CYTOCHROME P450 FAMILY 24 SUBFAMILY A MEMBER 1 UniProtKB/TrEMBL
  PTHR24279 UniProtKB/TrEMBL
Pfam p450 UniProtKB/TrEMBL
PRINTS EP450I UniProtKB/TrEMBL
  MITP450CC24 UniProtKB/TrEMBL
  P450 UniProtKB/TrEMBL
PROSITE CYTOCHROME_P450 UniProtKB/TrEMBL
Superfamily-SCOP SSF48264 UniProtKB/TrEMBL
UniProt A0A2R9BPE7 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BYF3 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:83045 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-02-25 CYP24A1  cytochrome P450 family 24 subfamily A member 1  LOC100971976  1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial  Symbol and/or name change 5135510 APPROVED