CYP24A1 (cytochrome P450 family 24 subfamily A member 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: CYP24A1 (cytochrome P450 family 24 subfamily A member 1) Pan paniscus
Analyze
Symbol: CYP24A1
Name: cytochrome P450 family 24 subfamily A member 1
RGD ID: 11842836
Description: ENCODES a protein that exhibits 25-hydroxycholecalciferol-24-hydroxylase activity (ortholog); vitamin D 24-hydroxylase activity (ortholog); INVOLVED IN cellular response to vitamin D (ortholog); vitamin D metabolic process (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); breast carcinoma (ortholog); Breast Neoplasms (ortholog); FOUND IN mitochondrial inner membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial; LOC100971976
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22159,906,065 - 59,926,662 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12059,899,186 - 59,919,783 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02050,500,103 - 50,520,487 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12051,721,895 - 51,742,716 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2051,721,685 - 51,742,716 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CYP24A1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22159,906,065 - 59,926,662 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12059,899,186 - 59,919,783 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02050,500,103 - 50,520,487 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12051,721,895 - 51,742,716 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2051,721,685 - 51,742,716 (-)Ensemblpanpan1.1panPan2
CYP24A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382054,143,538 - 54,173,986 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2054,153,446 - 54,173,986 (-)EnsemblGRCh38hg38GRCh38
GRCh372052,769,985 - 52,790,525 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362052,203,395 - 52,223,931 (-)NCBINCBI36Build 36hg18NCBI36
Celera2049,474,643 - 49,495,166 (-)NCBICelera
Cytogenetic Map20q13.2NCBI
HuRef2049,516,544 - 49,537,045 (-)NCBIHuRef
CHM1_12052,673,171 - 52,693,667 (-)NCBICHM1_1
T2T-CHM13v2.02055,917,843 - 55,948,320 (-)NCBIT2T-CHM13v2.0
Cyp24a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392170,324,877 - 170,339,065 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2170,324,628 - 170,339,065 (-)EnsemblGRCm39 Ensembl
GRCm382170,482,957 - 170,497,145 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2170,482,708 - 170,497,145 (-)EnsemblGRCm38mm10GRCm38
MGSCv372170,308,465 - 170,322,638 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362170,174,170 - 170,188,343 (-)NCBIMGSCv36mm8
Celera2176,437,445 - 176,451,588 (-)NCBICelera
Cytogenetic Map2H3NCBI
cM Map291.91NCBI
Cyp24a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83179,694,647 - 179,709,083 (-)NCBIGRCr8
mRatBN7.23159,275,947 - 159,290,383 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3159,275,947 - 159,290,383 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3163,075,289 - 163,089,740 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03171,574,931 - 171,589,382 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03169,316,153 - 169,330,604 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03168,097,484 - 168,111,920 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3168,097,485 - 168,111,920 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03174,200,349 - 174,214,780 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43161,542,131 - 161,553,801 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13161,445,746 - 161,460,193 (-)NCBI
Celera3157,820,209 - 157,834,648 (-)NCBICelera
Cytogenetic Map3q42NCBI
LOC102013768
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554454,873,942 - 4,891,780 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554454,874,583 - 4,891,723 (+)NCBIChiLan1.0ChiLan1.0
CYP24A1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12439,861,018 - 39,878,161 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2439,862,355 - 39,878,216 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2439,106,835 - 39,123,588 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02440,574,274 - 40,591,063 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2440,576,845 - 40,591,462 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12439,809,842 - 39,826,569 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02439,945,173 - 39,961,923 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02440,527,730 - 40,544,495 (-)NCBIUU_Cfam_GSD_1.0
LOC101957714
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640186,013,122 - 186,029,747 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365141,467,261 - 1,480,185 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365141,467,460 - 1,480,185 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CYP24A1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1755,110,590 - 55,130,363 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11755,110,546 - 55,130,328 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21761,891,352 - 61,912,269 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CYP24A1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.129,868,794 - 9,889,510 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl29,868,678 - 9,885,884 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605057,988,669 - 58,009,485 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LOC101716773
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247902,182,598 - 2,200,425 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247902,183,079 - 2,200,219 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000054405   ⟹   ENSPPAP00000031540
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2051,721,685 - 51,742,716 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000054407   ⟹   ENSPPAP00000031542
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2051,721,685 - 51,742,716 (-)Ensembl
RefSeq Acc Id: XM_055104799   ⟹   XP_054960774
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22159,906,065 - 59,926,662 (-)NCBI
NHGRI_mPanPan12059,902,225 - 59,919,373 (-)NCBI
RefSeq Acc Id: XM_055104800   ⟹   XP_054960775
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22159,906,065 - 59,926,662 (-)NCBI
NHGRI_mPanPan12059,902,225 - 59,919,373 (-)NCBI
RefSeq Acc Id: XM_063601018   ⟹   XP_063457088
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22159,906,065 - 59,926,662 (-)NCBI
Protein Sequences
Protein RefSeqs XP_054960774 (Get FASTA)   NCBI Sequence Viewer  
  XP_054960775 (Get FASTA)   NCBI Sequence Viewer  
  XP_063457088 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000031540.1
  ENSPPAP00000031542.1
Reference Protein Sequences
RefSeq Acc Id: ENSPPAP00000031540   ⟸   ENSPPAT00000054405
RefSeq Acc Id: ENSPPAP00000031542   ⟸   ENSPPAT00000054407
RefSeq Acc Id: XP_054960775   ⟸   XM_055104800
- Peptide Label: isoform X2
- UniProtKB: A0A2R9BYF3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054960774   ⟸   XM_055104799
- Peptide Label: isoform X1
- UniProtKB: A0A2R9BPE7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063457088   ⟸   XM_063601018
- Peptide Label: isoform X2


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000038708 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000054405.1 UniProtKB/TrEMBL
  ENSPPAT00000054407.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.630.10 UniProtKB/TrEMBL
InterPro Cyt_P450 UniProtKB/TrEMBL
  Cyt_P450_CS UniProtKB/TrEMBL
  Cyt_P450_E_CYP24A_mit UniProtKB/TrEMBL
  Cyt_P450_E_grp-I UniProtKB/TrEMBL
  Cyt_P450_sf UniProtKB/TrEMBL
NCBI Gene LOC100971976 ENTREZGENE
PANTHER CYTOCHROME P450 FAMILY 24 SUBFAMILY A MEMBER 1 UniProtKB/TrEMBL
  PTHR24279 UniProtKB/TrEMBL
Pfam p450 UniProtKB/TrEMBL
PRINTS EP450I UniProtKB/TrEMBL
  MITP450CC24 UniProtKB/TrEMBL
  P450 UniProtKB/TrEMBL
PROSITE CYTOCHROME_P450 UniProtKB/TrEMBL
Superfamily-SCOP SSF48264 UniProtKB/TrEMBL
UniProt A0A2R9BPE7 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9BYF3 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:83045 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-02-25 CYP24A1  cytochrome P450 family 24 subfamily A member 1  LOC100971976  1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial  Symbol and/or name change 5135510 APPROVED