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Gene: Tfap2c (transcription factor AP-2 gamma) Rattus norvegicus

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Symbol:

Tfap2c

Name:

transcription factor AP-2 gamma

RGD ID:

1303185

Description:

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription repressor activity, RNA polymerase II-specific; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in male gonad development; regulation of cell population proliferation; and regulation of gene expression. Predicted to act upstream of or within several processes, including branch elongation involved in mammary gland duct branching; forebrain development; and keratinocyte development. Predicted to be located in mitochondrion and nucleoplasm. Predicted to be active in nucleus. Orthologous to human TFAP2C (transcription factor AP-2 gamma); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

activating enhancer binding protein 2 gamma; activator protein 2 gamma; AP2-gamma; Tcfap2c; transcription factor AP-2, gamma

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TFAP2C (transcription factor AP-2 gamma)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, PhylomeDB
Mus musculus (house mouse):	Tfap2c (transcription factor AP-2, gamma)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Tfap2c (transcription factor AP-2 gamma)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TFAP2C (transcription factor AP-2 gamma)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TFAP2C (transcription factor AP-2 gamma)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Tfap2c (transcription factor AP-2 gamma)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TFAP2C (transcription factor AP-2 gamma)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	TFAP2C (transcription factor AP-2 gamma)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Tfap2c (transcription factor AP-2 gamma)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	TFAP2C (transcription factor AP-2 gamma)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Tfap2c (transcription factor AP-2, gamma)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	tfap2c (transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma))	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	aptf-1	Alliance	DIOPT (InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	TfAP-2	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	tfap2c	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)

Allele / Splice:

Tfap2c^{em1(tdTomato)Nips}

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	181,733,524 - 181,742,412 (+)	NCBI		GRCr8
mRatBN7.2	3	161,315,114 - 161,322,998 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	161,315,031 - 161,322,995 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	165,125,260 - 165,133,143 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	173,624,296 - 173,632,179 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	171,366,110 - 171,373,995 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	170,550,314 - 170,558,197 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	170,550,314 - 170,558,194 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	176,625,472 - 176,633,355 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	163,459,283 - 163,467,166 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	163,365,524 - 163,373,057 (+)	NCBI
Celera	3	160,513,939 - 160,521,822 (+)	NCBI		Celera
Cytogenetic Map	3	q42	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

microcephaly (ISO)

Stomach Neoplasms (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO)

4,4'-sulfonyldiphenol (ISO)

5-aza-2'-deoxycytidine (ISO)

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

all-trans-retinoic acid (ISO)

amiodarone (ISO)

arsenite(3-) (ISO)

arsenous acid (ISO)

belinostat (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bisphenol A (EXP,ISO)

cadmium dichloride (ISO)

carbamazepine (ISO)

carmustine (ISO)

chromium atom (ISO)

cisplatin (ISO)

clofibrate (ISO)

clomiphene (ISO)

copper atom (EXP)

copper(0) (EXP)

coumestrol (ISO)

crocidolite asbestos (ISO)

cylindrospermopsin (ISO)

diarsenic trioxide (ISO)

diethylstilbestrol (ISO)

dorsomorphin (ISO)

endosulfan (EXP)

Enterolactone (ISO)

entinostat (ISO)

estrone (ISO)

flusilazole (ISO)

fonofos (ISO)

fulvestrant (ISO)

genistein (EXP,ISO)

hemin (EXP)

hexaconazole (ISO)

hexadecanoic acid (ISO)

hexestrol (ISO)

hydrogen peroxide (ISO)

Indeno[1,2,3-cd]pyrene (ISO)

menadione (ISO)

mercury dibromide (ISO)

mestranol (ISO)

methapyrilene (ISO)

methylisothiazolinone (ISO)

methylmercury chloride (ISO)

mono(2-ethylhexyl) phthalate (ISO)

nickel sulfate (ISO)

Octicizer (ISO)

paclitaxel (ISO)

panobinostat (ISO)

paracetamol (ISO)

parathion (ISO)

PCB138 (ISO)

picene (ISO)

potassium chromate (ISO)

progesterone (ISO)

raloxifene (ISO)

resveratrol (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

temozolomide (ISO)

terbufos (ISO)

thiram (ISO)

titanium dioxide (ISO)

triadimefon (ISO)

trichostatin A (ISO)

valproic acid (EXP,ISO)

vinclozolin (EXP)

vorinostat (ISO)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

cerebral cortex development (ISO)

dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis (ISO)

epithelial cell differentiation (ISO)

epithelial cell proliferation involved in mammary gland duct elongation (ISO)

forebrain neuron fate commitment (ISO)

germ-line stem cell population maintenance (ISO)

hair follicle development (ISO)

keratinocyte development (ISO)

male gonad development (ISO)

negative regulation of gene expression, epigenetic (ISO)

negative regulation of transcription by RNA polymerase II (IEA)

positive regulation of transcription by RNA polymerase II (IBA,ISO)

regulation of cell population proliferation (IBA)

regulation of DNA-templated transcription (ISO)

regulation of epidermis development (ISO)

regulation of transcription by RNA polymerase II (ISO)

sebaceous gland development (ISO)

skin development (ISO)

somatic stem cell population maintenance (ISO)

stem cell differentiation (ISO)

stem cell population maintenance (ISO)

transcription by RNA polymerase II (ISO)

trophectodermal cell differentiation (ISO)

Cellular Component

mitochondrion (IEA,ISO)

nucleoplasm (IEA,ISO)

nucleus (IBA,ISO)

Molecular Function

DNA binding (ISO)

DNA-binding transcription activator activity, RNA polymerase II-specific (IBA,ISO)

DNA-binding transcription factor activity (ISO)

DNA-binding transcription factor activity, RNA polymerase II-specific (ISO)

DNA-binding transcription repressor activity, RNA polymerase II-specific (ISO)

protein binding (ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (ISO)

RNA polymerase II transcription regulatory region sequence-specific DNA binding (IBA,ISO)

sequence-specific double-stranded DNA binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	GOA pipeline	RGD automated data pipeline
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	Comprehensive gene review and curation	RGD comprehensive gene curation
7.	[The methods of irradiation dose fractionation and rate change used in studying the capacity for the postradiation repair of CFU-s forming splenic colonies after 8 and 12 days following bone marrow cell transplantation]	Trishkina AI and Konopliannikov AG, Radiobiologiia. 1992 Mar-Apr;32(2):312-6.
8.	Chromosomal mapping of the human and mouse homologues of two new members of the AP-2 family of transcription factors.	Williamson JA, etal., Genomics 1996 Jul 1;35(1):262-4.

Additional References at PubMed

PMID:8349681	PMID:9765260	PMID:10068641	PMID:11278550	PMID:11694877	PMID:11940672	PMID:12072434	PMID:12477932	PMID:15475956	PMID:16794002	PMID:17848411	PMID:18353300
PMID:18824566	PMID:19749747	PMID:19776388	PMID:20131354	PMID:20176728	PMID:20404091	PMID:22735262	PMID:24413532

Genomics

Comparative Map Data

Tfap2c
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	181,733,524 - 181,742,412 (+)	NCBI		GRCr8
mRatBN7.2	3	161,315,114 - 161,322,998 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	161,315,031 - 161,322,995 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	165,125,260 - 165,133,143 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	173,624,296 - 173,632,179 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	171,366,110 - 171,373,995 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	170,550,314 - 170,558,197 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	170,550,314 - 170,558,194 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	176,625,472 - 176,633,355 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	163,459,283 - 163,467,166 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	163,365,524 - 163,373,057 (+)	NCBI
Celera	3	160,513,939 - 160,521,822 (+)	NCBI		Celera
Cytogenetic Map	3	q42	NCBI

TFAP2C
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	20	56,629,306 - 56,639,283 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	20	56,629,306 - 56,639,283 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	20	55,204,362 - 55,214,339 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	20	54,637,765 - 54,647,746 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	20	54,637,764 - 54,647,743	NCBI
Celera	20	51,944,825 - 51,954,806 (+)	NCBI		Celera
Cytogenetic Map	20	q13.31	NCBI
HuRef	20	51,987,732 - 51,997,716 (+)	NCBI		HuRef
CHM1_1	20	55,105,529 - 55,115,512 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	20	58,406,836 - 58,416,813 (+)	NCBI		T2T-CHM13v2.0

Tfap2c
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	172,387,599 - 172,400,542 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	172,391,513 - 172,400,542 (+)	Ensembl		GRCm39 Ensembl
GRCm38	2	172,545,678 - 172,558,622 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	172,549,593 - 172,558,622 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	172,375,093 - 172,384,122 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	172,240,819 - 172,249,814 (+)	NCBI		MGSCv36	mm8
Celera	2	178,514,773 - 178,523,807 (+)	NCBI		Celera
Cytogenetic Map	2	H3	NCBI
cM Map	2	94.87	NCBI

Tfap2c
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955445	2,626,823 - 2,636,607 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955445	2,626,896 - 2,636,607 (-)	NCBI	ChiLan1.0	ChiLan1.0

TFAP2C
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	21	62,379,860 - 62,389,842 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	20	62,373,001 - 62,386,958 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	20	52,966,907 - 52,981,024 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	20	54,251,329 - 54,265,432 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	20	54,255,489 - 54,265,432 (+)	Ensembl	panpan1.1		panPan2

TFAP2C
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	24	41,787,477 - 41,797,446 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	24	41,783,490 - 41,796,509 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	24	41,034,501 - 41,044,940 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	24	42,549,083 - 42,559,516 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	24	42,545,543 - 42,559,496 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	24	41,737,165 - 41,747,589 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	24	41,875,939 - 41,886,373 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	24	42,534,235 - 42,544,660 (+)	NCBI		UU_Cfam_GSD_1.0

Tfap2c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	183,587,226 - 183,594,926 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936875	491,017 - 498,734 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936875	491,032 - 498,732 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TFAP2C
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	57,164,404 - 57,174,107 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	17	57,164,400 - 57,174,923 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	17	64,328,292 - 64,338,822 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TFAP2C
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	7,477,262 - 7,489,213 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666050	55,550,014 - 55,560,004 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Tfap2c
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624741	23,290,519 - 23,298,121 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624741	23,286,526 - 23,299,318 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Tfap2c
24 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	37
Count of miRNA genes:	35
Interacting mature miRNAs:	37
Transcripts:	ENSRNOT00000006991
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
12879876	Bw182	Body weight QTL 182		0.003	body mass (VT:0001259)	body weight (CMO:0000012)	3	145925360	166177555	Rat
2301411	Bp320	Blood pressure QTL 320		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	145925360	166177555	Rat
2312673	Scl63	Serum cholesterol level QTL 63		0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	3	98535255	168026850	Rat
12879872	Cm97	Cardiac mass QTL 97		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	145925360	166177555	Rat
1598877	Bp285	Blood pressure QTL 285	1.5	0.03	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	120538241	165538241	Rat
1578653	Vnigr3	Vascular neointimal growth QTL 3	3.1		artery morphology trait (VT:0002191)	artery neointimal hyperplastic lesion area (CMO:0001414)	3	130656562	169034231	Rat
12879873	Cm96	Cardiac mass QTL 96		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	3	145925360	166177555	Rat
2302373	Gluco39	Glucose level QTL 39	5.01		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	3	98535386	161695835	Rat
12879874	Cm98	Cardiac mass QTL 98		0.005	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	3	145925360	166177555	Rat
1298068	Bp167	Blood pressure QTL 167		0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	141074471	169034231	Rat
12879875	Kidm64	Kidney mass QTL 64		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	145925360	166177555	Rat
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	31172320	163586636	Rat
2298477	Eau4	Experimental allergic uveoretinitis QTL 4		0.0011	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	3	137398739	169034231	Rat
1300161	Rf10	Renal function QTL 10	3.57		renal blood flow trait (VT:2000006)	absolute change in renal vascular resistance (CMO:0001900)	3	161192952	169034231	Rat
8552791	Vie2	Viral induced encephalitis QTL 2	4.1		brain integrity trait (VT:0010579)	encephalitis incidence/prevalence measurement (CMO:0002361)	3	145956084	169034231	Rat
2317883	Alcrsp26	Alcohol response QTL 26	1.8	0.63	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	3	145526770	169034231	Rat
1331726	Bp208	Blood pressure QTL 208	3.129		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	141339013	162184794	Rat
9589106	Insul23	Insulin level QTL 23	13.86	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	3	131635904	169034231	Rat
10755461	Coatc16	Coat color QTL 16			coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	3	122438700	167438700	Rat
1559282	Emca5	Estrogen-induced mammary cancer QTL 5	3.9		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	3	43827364	169034231	Rat
2303620	Vencon4	Ventilatory control QTL 4	3.9		respiration trait (VT:0001943)	tidal volume (CMO:0000222)	3	127162703	168026850	Rat
1576306	Schws3	Schwannoma susceptibility QTL 3		0.001	nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	3	118839124	163839124	Rat
2312659	Slep7	Serum leptin concentration QTL 7		0.001	blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	3	98535255	168026850	Rat
631673	Iddm13	Insulin dependent diabetes mellitus QTL 13	1.3	0.663	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	3	130193298	161695983	Rat
1578666	Vnigr1	Vascular neointimal growth QTL 1	4.6		artery morphology trait (VT:0002191)	artery lumen area (CMO:0001409)	3	149040888	168026850	Rat
1578656	Vnigr2	Vascular neointimal growth QTL 2	4.2		artery morphology trait (VT:0002191)	lesioned artery residual lumen area (CMO:0001417)	3	130656562	169034231	Rat
8552952	Pigfal13	Plasma insulin-like growth factor 1 level QTL 13			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	3	138799500	169034231	Rat
12879871	Am7	Aortic mass QTL 7		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	3	145925360	166177555	Rat
631541	Bp81	Blood pressure QTL 81	4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	124122556	169034231	Rat
2312670	Bw94	Body weight QTL 94		0.01	inguinal fat pad mass (VT:0010424)	inguinal fat pad weight to body weight ratio (CMO:0001253)	3	98535255	168026850	Rat

Markers in Region

RH130934

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	161,322,773 - 161,322,959 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	170,557,973 - 170,558,158	NCBI	Rnor6.0
Rnor_5.0	3	176,633,131 - 176,633,316	UniSTS	Rnor5.0
RGSC_v3.4	3	163,466,942 - 163,467,127	UniSTS	RGSC3.4
Celera	3	160,521,598 - 160,521,783	UniSTS
RH 3.4 Map	3	1493.1	UniSTS
Cytogenetic Map	3	q42	UniSTS

PMC133770P1

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	161,319,439 - 161,319,726 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	170,554,639 - 170,554,925	NCBI	Rnor6.0
Rnor_5.0	3	176,629,797 - 176,630,083	UniSTS	Rnor5.0
RGSC_v3.4	3	163,463,608 - 163,463,894	UniSTS	RGSC3.4
Celera	3	160,518,264 - 160,518,550	UniSTS
Cytogenetic Map	3	q42	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
3	1	15	93	28	41	11	10	11	6	81	30	87	36	59	30

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_201420	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006235691	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AY510602	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC097260	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474062	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000006991 ⟹ ENSRNOP00000006991

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	161,315,031 - 161,322,995 (+)	Ensembl
Rnor_6.0 Ensembl	3	170,550,314 - 170,558,194 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000097561 ⟹ ENSRNOP00000077725

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	161,315,888 - 161,322,995 (+)	Ensembl

RefSeq Acc Id:

NM_201420 ⟹ NP_958823

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	181,733,524 - 181,741,407 (+)	NCBI
mRatBN7.2	3	161,315,114 - 161,322,998 (+)	NCBI
Rnor_6.0	3	170,550,314 - 170,558,197 (+)	NCBI
Rnor_5.0	3	176,625,472 - 176,633,355 (+)	NCBI
RGSC_v3.4	3	163,459,283 - 163,467,166 (+)	RGD
Celera	3	160,513,939 - 160,521,822 (+)	RGD

Sequence:

show sequence

CTCCGGTCCACCGCTGCGGCCTCTACACACCCACCGCGGCCACATCTACGTGCACAGCCACCGA
TGCGCGACCAGTGACTGGGACAGCGAGGCCCGCGCGCGGCGGGGGCGGCGGCAGACGCCTGGCC
ACCGTGACCCCGATTGTGGATTTACCGCTCGGGGGGTGGGGGGAGCCTGGATTTAACTGGCGAC
TATTTTGGGGGACGCCGGACGCCATGTTGTGGAAAATAACAGATAATGTCAAGTATGAAGAGGA
TTGCGAGGATCGCCACGACGCGAGCAGTAATGGGAACCCTCGCATCCCTCACCTCTCATCTGCG
GGACAGCATCTCTACAGTCCCGCGCCGCCTCTCTCGCACACCGGGGTTGCAGAGTACCAGCCGC
CTCCTTACTTCCCGCCGCCCTACCAGCAGTTGGCATACTCGCAATCCGCCGATCATTACTCGCA
CTTGGGAGAGGCTTACGCTGCCGCCATCAACCCCTTGCACCAGCCTGCGCCCACCGGCAGCCAG
CAACAGGCCTGGCCAGGTCGACAGAGTCAGGAGGGCTCTAGCCTGGCTTCGCACCACGGCCGCT
CTGCAGGTCTTATACCCCATATTTCAGGGCTGGAGGGGAGCGCGGTGAGTTCCCGGCGGGAAGC
CTACCGCCGTTCCGATCTGCTGCTGCCTCACGCGCACGCCCTGGAAGCCGCCGGCCTGGCTGAG
AACCTAGGGCTGCACGAGATGGCTCACCCCATTGAGGAGGTGCAGAACGTGGACGACCCGCATC
TGCTTCTACACGATCAGACTGTCATTCGCAAAGGACCCATTTCAATGACCAAGAACCCTCTGGG
CCTCCCTTGCCAGAAGGACCTAGTTGGAGCGGTCATGAACCCCAGCGAGGTCTTCTGCTCCGTT
CCTGGAAGACTCTCCCTGTTGAGCTCCACCTCGAAGTACAAAGTAACCGTGGCTGAGGTACAGA
GGCGACTGTCACCACCGGAATGCTTGAATGCCTCGCTCCTGGGAGGCGTGCTCAGAAGAGCGAA
ATCCAAAAATGGAGGCCGGTCCTTGAGGGAGAAGTTGGACAAAATTGGGCTGAACCTTCCAGCT
GGGAGACGGAAAGCCGCCCATGTCACTCTCCTCACATCTCTCGTGGAAGGCGAGGCCGTCCACC
TAGCCCGGGACTTTGCCTACGTCTGCGAAGCTGAGTTTCCCAGTAAAGCAGTGGCTGACTATTT
AACCAGACCGCATCTTGGGGGACGGAACGAGATGGCCGCTAGGAAGAGTGTGTTGTTGGCAGCA
CAGCAAGTGTGCAAGGAGTTCACTGACCTCCTCCATCAAGACCGAACGCCCAACGGGAACAGCA
GGCCCACCCCGGTCTTGGAGACGAACATACAAAACTGCTTGTCTCATTTCAGCCTGATAACTCA
TGGCTTTGGCAGCCAGGCCATCTGCGCAGCGGTCTCTGCTGTGCAGAATTATATCAAGGAGGCC
CTAATCACCATCGACAAGTCCTACATGAACCCGGGAGAGCAGAGTCCGGCTGATTCCAACAAGA
CGATGGAGAAAATGGAAAAGCACCGGAAGTAAAGTGGGATCGAGGAGGCCAGAAAGCGGAAGGA
GAGAGGACCCAAGCCCCCTCCACTGGGGCAGCCTGGGAAGCCCTCATCGGGGCGGTTACCACCC
ACCTCACTTTGGACCTCTGCCCTCTTGGAGTCTTTGTGACTTTTCCATTTAACCCTGGACATGC
TATCCCGAAGCTACTTGGTTTGGTTCTTTTATTCATTAAACATTGTTTTTTTGGAAAAAAAAAA
AAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006235691 ⟹ XP_006235753

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	181,734,315 - 181,742,412 (+)	NCBI
mRatBN7.2	3	161,315,905 - 161,322,998 (+)	NCBI
Rnor_6.0	3	170,551,081 - 170,557,980 (+)	NCBI
Rnor_5.0	3	176,625,472 - 176,633,355 (+)	NCBI

Sequence:

show sequence

ATGGGGCCTTGAGCGCTCGCGAGTACTCTAGCCTGTCGGACAGGTTGAGCTAGAGTTTCGGAGA
GTAGGAGGGAGGGAGGCGGCGAGCGGGAAGAGGAAGAAGATTCTGGCGGCGCGAGGCGAGCACC
GGGGAGCGTGGAGAGGAGAGCCCGAGCGGCCAGGCTGCGGGAGCGCACCGCGCCCGCAAGACCT
CGAGGGGCTGCCCCTGCGTGCACGCCCGGGCGCTTCCGCTAGGGGGCGACAGTGCCCCGCTCCT
GCGTCCCTGCTACCCTTCTGACCCCTGGGACTGATGAAGACACATCTTTTAGGAATTAAGTCTG
ACCGCCTTGAGGCGAGGGGACGTGCGCAGGCAAAGGTTGCCCAATTTGGCAGAGTCTTTTCATT
CCTTCTCTACACCGGGATGTGTGAGAACCTTGACCGTGGCCGGTCCGGAAGACCTCACTTCCAA
AGGCGCAGAAGGCACGGGCTTGACTAGCAAGGATCACAGCTCCCGGTCCCGCGTGTTGGCGCCC
GAGCCTCTCTGGACGACTTTACCTATCAGGCCTTACCTTGGGAGTGTCACTTCCGCGGCGTTGC
CGCCTCTTAAGGGGGATGATCCTTAGGGCGGGGGAAACGTGCCCTTCGTCGGCGTTGCGTATTA
TCCGCGCCGACTGTTCTTGGCGCGCCGCGGCATGGGAGGAGGGTTGATGAGCAAGGGCGCTTTG
CGCCGAGGCCGCCGCACGCCGACCCCCGGCGGCACCGGCTACCGTGCCGTGGCCCGGAACGCGC
CCTTGGCACCTCCAAGCGCCGCCAGCGACGAAGCACGGGAGCCTTCGCCAGTGTGCTTGAAGGA
CTCGCTCTCTCAGGATCGCCACGACGCGAGCAGTAATGGGAACCCTCGCATCCCTCACCTCTCA
TCTGCGGGACAGCATCTCTACAGTCCCGCGCCGCCTCTCTCGCACACCGGGGTTGCAGAGTACC
AGCCGCCTCCTTACTTCCCGCCGCCCTACCAGCAGTTGGCATACTCGCAATCCGCCGATCATTA
CTCGCACTTGGGAGAGGCTTACGCTGCCGCCATCAACCCCTTGCACCAGCCTGCGCCCACCGGC
AGCCAGCAACAGGCCTGGCCAGGTCGACAGAGTCAGGAGGGCTCTAGCCTGGCTTCGCACCACG
GCCGCTCTGCAGGTCTTATACCCCATATTTCAGGGCTGGAGGGGAGCGCGGTGAGTTCCCGGCG
GGAAGCCTACCGCCGTTCCGATCTGCTGCTGCCTCACGCGCACGCCCTGGAAGCCGCCGGCCTG
GCTGAGAACCTAGGGCTGCACGAGATGGCTCACCCCATTGAGGAGGTGCAGAACGTGGACGACC
CGCATCTGCTTCTACACGATCAGACTGTCATTCGCAAAGGACCCATTTCAATGACCAAGAACCC
TCTGGGCCTCCCTTGCCAGAAGGACCTAGTTGGAGCGGTCATGAACCCCAGCGAGGTCTTCTGC
TCCGTTCCTGGAAGACTCTCCCTGTTGAGCTCCACCTCGAAGTACAAAGTAACCGTGGCTGAGG
TACAGAGGCGACTGTCACCACCGGAATGCTTGAATGCCTCGCTCCTGGGAGGCGTGCTCAGAAG
AGCGAAATCCAAAAATGGAGGCCGGTCCTTGAGGGAGAAGTTGGACAAAATTGGGCTGAACCTT
CCAGCTGGGAGACGGAAAGCCGCCCATGTCACTCTCCTCACATCTCTCGTGGAAGGCGAGGCCG
TCCACCTAGCCCGGGACTTTGCCTACGTCTGCGAAGCTGAGTTTCCCAGTAAAGCAGTGGCTGA
CTATTTAACCAGACCGCATCTTGGGGGACGGAACGAGATGGCCGCTAGGAAGAGTGTGTTGTTG
GCAGCACAGCAAGTGTGCAAGGAGTTCACTGACCTCCTCCATCAAGACCGAACGCCCAACGGGA
ACAGCAGGCCCACCCCGGTCTTGGAGACGAACATACAAAACTGCTTGTCTCATTTCAGCCTGAT
AACTCATGGCTTTGGCAGCCAGGCCATCTGCGCAGCGGTCTCTGCTGTGCAGAATTATATCAAG
GAGGCCCTAATCACCATCGACAAGTCCTACATGAACCCGGGAGAGCAGAGTCCGGCTGATTCCA
ACAAGACGATGGAGAAAATGGAAAAGCACCGGAAGTAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_958823	(Get FASTA)	NCBI Sequence Viewer
	XP_006235753	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH97260	(Get FASTA)	NCBI Sequence Viewer
	AAR97340	(Get FASTA)	NCBI Sequence Viewer
	EDL85139	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000006991.6
	ENSRNOP00000077725.1

RefSeq Acc Id:

NP_958823 ⟸ NM_201420

- UniProtKB:

Q4V8P9 (UniProtKB/TrEMBL), Q6R5Q0 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MLWKITDNVKYEEDCEDRHDASSNGNPRIPHLSSAGQHLYSPAPPLSHTGVAEYQPPPYFPPPY
QQLAYSQSADHYSHLGEAYAAAINPLHQPAPTGSQQQAWPGRQSQEGSSLASHHGRSAGLIPHI
SGLEGSAVSSRREAYRRSDLLLPHAHALEAAGLAENLGLHEMAHPIEEVQNVDDPHLLLHDQTV
IRKGPISMTKNPLGLPCQKDLVGAVMNPSEVFCSVPGRLSLLSSTSKYKVTVAEVQRRLSPPEC
LNASLLGGVLRRAKSKNGGRSLREKLDKIGLNLPAGRRKAAHVTLLTSLVEGEAVHLARDFAYV
CEAEFPSKAVADYLTRPHLGGRNEMAARKSVLLAAQQVCKEFTDLLHQDRTPNGNSRPTPVLET
NIQNCLSHFSLITHGFGSQAICAAVSAVQNYIKEALITIDKSYMNPGEQSPADSNKTMEKMEKH
RK

hide sequence

RefSeq Acc Id:	XP_006235753 ⟸ XM_006235691
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I5XWF9 (UniProtKB/TrEMBL), Q6R5Q0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGGGLMSKGALRRGRRTPTPGGTGYRAVARNAPLAPPSAASDEAREPSPVCLKDSLSQDRHDAS SNGNPRIPHLSSAGQHLYSPAPPLSHTGVAEYQPPPYFPPPYQQLAYSQSADHYSHLGEAYAAA INPLHQPAPTGSQQQAWPGRQSQEGSSLASHHGRSAGLIPHISGLEGSAVSSRREAYRRSDLLL PHAHALEAAGLAENLGLHEMAHPIEEVQNVDDPHLLLHDQTVIRKGPISMTKNPLGLPCQKDLV GAVMNPSEVFCSVPGRLSLLSSTSKYKVTVAEVQRRLSPPECLNASLLGGVLRRAKSKNGGRSL REKLDKIGLNLPAGRRKAAHVTLLTSLVEGEAVHLARDFAYVCEAEFPSKAVADYLTRPHLGGR NEMAARKSVLLAAQQVCKEFTDLLHQDRTPNGNSRPTPVLETNIQNCLSHFSLITHGFGSQAIC AAVSAVQNYIKEALITIDKSYMNPGEQSPADSNKTMEKMEKHRK hide sequence

Ensembl Acc Id:

ENSRNOP00000006991 ⟸ ENSRNOT00000006991

Ensembl Acc Id:

ENSRNOP00000077725 ⟸ ENSRNOT00000097561

Protein Domains

Transcription factor AP-2 C-terminal

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q4V8P9-F1-model_v2	AlphaFold	Q4V8P9	1-450	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1303185	AgrOrtholog
BioCyc Gene	G2FUF-46534	BioCyc
Ensembl Genes	ENSRNOG00000005246	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000006991.6	UniProtKB/TrEMBL
	ENSRNOT00000097561.1	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7443035	IMAGE-MGC_LOAD
InterPro	TF_AP2	UniProtKB/TrEMBL
	TF_AP2_C	UniProtKB/TrEMBL
	TF_AP2_gamma	UniProtKB/TrEMBL
KEGG Report	rno:362280	UniProtKB/TrEMBL
MGC_CLONE	MGC:114227	IMAGE-MGC_LOAD
NCBI Gene	362280	ENTREZGENE
PANTHER	TF_AP2	UniProtKB/TrEMBL
	TRANSCRIPTION FACTOR AP-2 GAMMA	UniProtKB/TrEMBL
Pfam	TF_AP-2	UniProtKB/TrEMBL
PhenoGen	Tfap2c	PhenoGen
PRINTS	AP2CTNSCPFCT	UniProtKB/TrEMBL
	AP2TNSCPFCT	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000005246	RatGTEx
UniProt	A0A8I5XWF9	ENTREZGENE, UniProtKB/TrEMBL
	F7EWS2_RAT	UniProtKB/TrEMBL
	Q4V8P9	ENTREZGENE, UniProtKB/TrEMBL
	Q6R5Q0	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2011-06-09	Tfap2c	transcription factor AP-2 gamma	Tcfap2c	transcription factor AP-2, gamma	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-30	Tcfap2c	transcription factor AP-2, gamma			Symbol and Name status set to approved	1299863	APPROVED
2005-07-14	Tcfap2c	transcription factor AP-2, gamma			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD