Imported Disease Annotations - OMIMObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Sycp2 | Rat | spermatogenic failure 1 | | ISO | SYCP2 (Homo sapiens) | 7240710 | | OMIM | | |
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Imported Disease Annotations - OMIMObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Sycp2 | Rat | spermatogenic failure 1 | | ISO | SYCP2 (Homo sapiens) | 7240710 | | OMIM | | |
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# | Reference Title | Reference Citation |
1. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
2. | Rat ISS GO annotations from GOA human gene data--August 2006 | GOA data from the GO Consortium |
3. | Electronic Transfer of LocusLink and RefSeq Data | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
4. | SCP2: a major protein component of the axial elements of synaptonemal complexes of the rat. | Offenberg HH, etal., Nucleic Acids Res 1998 Jun 1;26(11):2572-9. |
5. | GOA pipeline | RGD automated data pipeline |
6. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
7. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
8. | Localization of SCP2 and SCP3 protein molecules within synaptonemal complexes of the rat. | Schalk JA, etal., Chromosoma. 1998 Dec;107(8):540-8. |
9. | Proteomics profiling of nuclear proteins for kidney fibroblasts suggests hypoxia, meiosis, and cancer may meet in the nucleus. | Shakib K, etal., Proteomics. 2005 Jul;5(11):2819-38. |
10. | Tentative Sequence Identification Numbers | Tentative Sequence Data IDs. TIGR Gene Index, Rat Data |
PMID:10341103 | PMID:10652260 | PMID:16717126 | PMID:18283110 | PMID:18316482 | PMID:19034475 | PMID:22011390 | PMID:22164254 | PMID:22711701 | PMID:23133398 | PMID:26362258 |
Sycp2 (Rattus norvegicus - Norway rat) |
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SYCP2 (Homo sapiens - human) |
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Sycp2 (Mus musculus - house mouse) |
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Sycp2 (Chinchilla lanigera - long-tailed chinchilla) |
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SYCP2 (Pan paniscus - bonobo/pygmy chimpanzee) |
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SYCP2 (Canis lupus familiaris - dog) |
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Sycp2 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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SYCP2 (Sus scrofa - pig) |
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SYCP2 (Chlorocebus sabaeus - green monkey) |
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Sycp2 (Heterocephalus glaber - naked mole-rat) |
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Variants in Sycp2
133 total Variants |
The detailed report is available here: | Full Report | CSV | TAB | Printer | ||||
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | Full Report | CSV | TAB | Printer | Gviewer |
D3Got171 |
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G65197 |
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alimentary part of gastrointestinal system
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appendage
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circulatory system
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ectoderm
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endocrine system
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endoderm
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exocrine system
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hemolymphoid system
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hepatobiliary system
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integumental system
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mesenchyme
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mesoderm
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nervous system
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renal system
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reproductive system
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respiratory system
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9 | 8 | 49 | 113 | 77 | 76 | 45 | 25 | 45 | 6 | 201 | 94 | 93 | 45 | 60 | 31 |
Ensembl Acc Id: | ENSRNOT00000078047 ⟹ ENSRNOP00000070540 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Ensembl Acc Id: | ENSRNOT00000079019 ⟹ ENSRNOP00000075596 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | NM_130735 ⟹ NP_570091 | ||||||||||||||||||||||||||||
RefSeq Status: | PROVISIONAL | ||||||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_039105970 ⟹ XP_038961898 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | XM_063284678 ⟹ XP_063140748 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063284679 ⟹ XP_063140749 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063284680 ⟹ XP_063140750 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063284681 ⟹ XP_063140751 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063284682 ⟹ XP_063140752 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063284683 ⟹ XP_063140753 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063284684 ⟹ XP_063140754 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | NP_570091 ⟸ NM_130735 |
- UniProtKB: | O70608 (UniProtKB/Swiss-Prot), A0A8L2R2I5 (UniProtKB/TrEMBL) |
- Sequence: |
Ensembl Acc Id: | ENSRNOP00000075596 ⟸ ENSRNOT00000079019 |
Ensembl Acc Id: | ENSRNOP00000070540 ⟸ ENSRNOT00000078047 |
RefSeq Acc Id: | XP_038961898 ⟸ XM_039105970 |
- Peptide Label: | isoform X4 |
- UniProtKB: | A0A8L2RBT5 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_063140751 ⟸ XM_063284681 |
- Peptide Label: | isoform X2 |
RefSeq Acc Id: | XP_063140754 ⟸ XM_063284684 |
- Peptide Label: | isoform X3 |
RefSeq Acc Id: | XP_063140748 ⟸ XM_063284678 |
- Peptide Label: | isoform X1 |
- UniProtKB: | O70608 (UniProtKB/Swiss-Prot) |
RefSeq Acc Id: | XP_063140749 ⟸ XM_063284679 |
- Peptide Label: | isoform X1 |
- UniProtKB: | O70608 (UniProtKB/Swiss-Prot) |
RefSeq Acc Id: | XP_063140752 ⟸ XM_063284682 |
- Peptide Label: | isoform X2 |
RefSeq Acc Id: | XP_063140750 ⟸ XM_063284680 |
- Peptide Label: | isoform X1 |
- UniProtKB: | O70608 (UniProtKB/Swiss-Prot) |
RefSeq Acc Id: | XP_063140753 ⟸ XM_063284683 |
- Peptide Label: | isoform X2 |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-O70608-F1-model_v2 | AlphaFold | O70608 | 1-1505 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
RGD ID: | 13692727 | ||||||||
Promoter ID: | EPDNEW_R3251 | ||||||||
Type: | multiple initiation site | ||||||||
Name: | Sycp2_1 | ||||||||
Description: | synaptonemal complex protein 2 | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
Experiment Methods: | Single-end sequencing. | ||||||||
Position: |
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Database | Acc Id | Source(s) |
AGR Gene | RGD:69429 | AgrOrtholog |
BioCyc Gene | G2FUF-46401 | BioCyc |
Ensembl Genes | ENSRNOG00000061690 | Ensembl, UniProtKB/TrEMBL |
ENSRNOG00055000804 | UniProtKB/Swiss-Prot | |
ENSRNOG00060001141 | UniProtKB/Swiss-Prot | |
ENSRNOG00065014245 | UniProtKB/Swiss-Prot | |
Ensembl Transcript | ENSRNOT00000078047.2 | UniProtKB/TrEMBL |
ENSRNOT00000079019.2 | UniProtKB/TrEMBL | |
ENSRNOT00055001381 | UniProtKB/Swiss-Prot | |
ENSRNOT00060001609 | UniProtKB/Swiss-Prot | |
ENSRNOT00065023517 | UniProtKB/Swiss-Prot | |
InterPro | ARM-type_fold | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
SYCP1/2 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
SYCP2_ARLD | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
SYCP2_SLD | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
KEGG Report | rno:83820 | UniProtKB/Swiss-Prot |
NCBI Gene | 83820 | ENTREZGENE |
PANTHER | PTHR15607 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PTHR15607:SF12 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Pfam | SYCP2_ARLD | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
SYCP2_SLD | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
PhenoGen | Sycp2 | PhenoGen |
RatGTEx | ENSRNOG00000061690 | RatGTEx |
ENSRNOG00055000804 | RatGTEx | |
ENSRNOG00060001141 | RatGTEx | |
ENSRNOG00065014245 | RatGTEx | |
Superfamily-SCOP | ARM repeat | UniProtKB/TrEMBL, UniProtKB/Swiss-Prot |
TIGR | TC210568 | |
UniProt | A0A8L2R2I5 | ENTREZGENE, UniProtKB/TrEMBL |
A0A8L2RBT5 | ENTREZGENE, UniProtKB/TrEMBL | |
A6KME8_RAT | UniProtKB/TrEMBL | |
A6KME9_RAT | UniProtKB/TrEMBL | |
O70608 | ENTREZGENE, UniProtKB/Swiss-Prot |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2002-06-10 | Sycp2 | synaptonemal complex protein 2 | Name updated | 70584 | APPROVED |
Note Type | Note | Reference |
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gene_expression | expressed specifically in the testis, in meiotic prophase cells | 69387 |
gene_function | may be a DNA-binding protein | 69387 |
gene_protein | molecular mass of 173 kDa | 69387 |