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Gene: Nfatc2 (nuclear factor of activated T-cells 2) Rattus norvegicus
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Symbol: Nfatc2
Name: nuclear factor of activated T-cells 2
Description: Predicted to have several functions, including DNA-binding transcription factor activity; RNA polymerase II proximal promoter sequence-specific DNA binding activity; and transcription factor binding activity. Predicted to be involved in several processes, including calcineurin-NFAT signaling cascade; regulation of muscle cell differentiation; and regulation of transcription by RNA polymerase II. Localizes to the cytosol and nucleus. Used to study pulmonary hypertension. Orthologous to human NFATC2 (nuclear factor of activated T cells 2); PARTICIPATES IN calcineurin signaling pathway; nuclear factor of activated T-cells signaling pathway; Wnt signaling, non-canonical pathway; INTERACTS WITH (RS)-amphetamine; copper atom; copper(0).
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC311658; nuclear factor of activated T-cells, cytoplasmic 2; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
Orthologs:
Homo sapiens (human) : NFATC2 (nuclear factor of activated T cells 2)  HGNC  Alliance
Mus musculus (house mouse) : Nfatc2 (nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nfatc2 (nuclear factor of activated T cells 2)
Pan paniscus (bonobo/pygmy chimpanzee) : NFATC2 (nuclear factor of activated T cells 2)
Canis lupus familiaris (dog) : NFATC2 (nuclear factor of activated T cells 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nfatc2 (nuclear factor of activated T cells 2)
Sus scrofa (pig) : NFATC2 (nuclear factor of activated T cells 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03165,241,750 - 165,374,644 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03171,380,993 - 171,514,802 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43159,656,032 - 159,773,643 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13159,560,378 - 159,679,702 (-)NCBI
Celera3155,769,159 - 155,882,096 (-)NCBICelera
Cytogenetic Map3q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Nfatc2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1307690
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.