Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of RAE1 mRNA] | CTD | PMID:31150632 | (1->4)-beta-D-glucan | multiple interactions | ISO | Rae1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of RAE1 mRNA | CTD | PMID:36331819 | 1,2-dimethylhydrazine | multiple interactions | ISO | Rae1 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of RAE1 mRNA | CTD | PMID:22206623 | 1,3-dinitrobenzene | increases expression | EXP | | 6480464 | 3-dinitrobenzene results in increased expression of RAE1 mRNA | CTD | PMID:21983209 | 17alpha-ethynylestradiol | increases expression | ISO | Rae1 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of RAE1 mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | multiple interactions | ISO | Rae1 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RAE1 mRNA | CTD | PMID:17942748 | 17beta-estradiol | affects expression | ISO | Rae1 (Mus musculus) | 6480464 | Estradiol affects the expression of RAE1 mRNA | CTD | PMID:15598610 | 2,2',4,4'-Tetrabromodiphenyl ether | affects expression | ISO | Rae1 (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:30294300 | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | ISO | RAE1 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Rae1 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of RAE1 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of RAE1 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Rae1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of RAE1 mRNA | CTD | PMID:21570461 | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of RAE1 mRNA | CTD | PMID:21346803 | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 6-dinitrotoluene affects the expression of RAE1 mRNA | CTD | PMID:21346803 | 2-methylcholine | affects expression | ISO | RAE1 (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of RAE1 mRNA | CTD | PMID:21179406 | 3,4-methylenedioxymethamphetamine | decreases expression | EXP | | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of RAE1 mRNA | CTD | PMID:30071829 | 4-amino-2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 4-amino-2 and 6-dinitrotoluene affects the expression of RAE1 mRNA | CTD | PMID:21346803 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of RAE1 mRNA | CTD | PMID:30047161 | amitrole | increases expression | EXP | | 6480464 | Amitrole results in increased expression of RAE1 mRNA | CTD | PMID:30047161 | aristolochic acid A | increases expression | ISO | RAE1 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of RAE1 mRNA and aristolochic acid I results in increased expression of RAE1 protein | CTD | PMID:33212167 | arsenite(3-) | multiple interactions | ISO | RAE1 (Homo sapiens) | 6480464 | arsenite promotes the reaction [G3BP1 protein binds to RAE1 mRNA] | CTD | PMID:32406909 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of RAE1 mRNA | CTD | PMID:25181051 and PMID:30816183 | bisphenol A | decreases expression | ISO | RAE1 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of RAE1 protein | CTD | PMID:31675489 | CGP 52608 | multiple interactions | ISO | RAE1 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to RAE1 gene] | CTD | PMID:28238834 | chlorpyrifos | increases methylation | EXP | | 6480464 | Chlorpyrifos results in increased methylation of RAE1 gene | CTD | PMID:32905263 | chlorpyrifos | decreases expression | ISO | Rae1 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of RAE1 mRNA | CTD | PMID:37019170 | copper(II) sulfate | increases expression | ISO | RAE1 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of RAE1 mRNA | CTD | PMID:19549813 | coumestrol | increases expression | ISO | RAE1 (Homo sapiens) | 6480464 | Coumestrol results in increased expression of RAE1 mRNA | CTD | PMID:19167446 | deoxynivalenol | increases expression | ISO | RAE1 (Homo sapiens) | 6480464 | deoxynivalenol results in increased expression of RAE1 mRNA | CTD | PMID:31863870 | dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of RAE1 mRNA | CTD | PMID:21266533 | dioxygen | multiple interactions | ISO | Rae1 (Mus musculus) | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of RAE1 mRNA and [sulforaphane affects the susceptibility to Oxygen] which affects the expression of RAE1 mRNA | CTD | PMID:30529165 | doxorubicin | increases expression | ISO | RAE1 (Homo sapiens) | 6480464 | Doxorubicin results in increased expression of RAE1 mRNA | CTD | PMID:29803840 | enzyme inhibitor | multiple interactions | ISO | RAE1 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of RAE1 protein | CTD | PMID:23301498 | ethanol | increases expression | ISO | Rae1 (Mus musculus) | 6480464 | Ethanol results in increased expression of RAE1 mRNA | CTD | PMID:30319688 | fenvalerate | increases expression | EXP | | 6480464 | fenvalerate results in increased expression of RAE1 mRNA | CTD | PMID:30307764 | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of RAE1 mRNA | CTD | PMID:24136188 | folic acid | multiple interactions | ISO | Rae1 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of RAE1 mRNA | CTD | PMID:22206623 | ivermectin | decreases expression | ISO | RAE1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of RAE1 protein | CTD | PMID:32959892 | methimazole | increases expression | EXP | | 6480464 | Methimazole results in increased expression of RAE1 mRNA | CTD | PMID:30047161 | methotrexate | increases expression | ISO | RAE1 (Homo sapiens) | 6480464 | Methotrexate results in increased expression of RAE1 mRNA | CTD | PMID:24449571 | methyl methanesulfonate | increases expression | ISO | RAE1 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of RAE1 mRNA | CTD | PMID:23649840 | ozone | multiple interactions | ISO | RAE1 (Homo sapiens) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which affects the expression of RAE1 mRNA | CTD | PMID:35430440 | paracetamol | affects expression | ISO | Rae1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of RAE1 mRNA | CTD | PMID:17562736 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Rae1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of RAE1 mRNA | CTD | PMID:36331819 | resveratrol | multiple interactions | ISO | RAE1 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of RAE1 mRNA | CTD | PMID:23557933 | rotenone | increases expression | ISO | RAE1 (Homo sapiens) | 6480464 | Rotenone results in increased expression of RAE1 mRNA | CTD | PMID:33512557 | SB 431542 | multiple interactions | ISO | RAE1 (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in increased expression of RAE1 protein | CTD | PMID:37664457 | sodium arsenite | decreases expression | ISO | Rae1 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of RAE1 mRNA | CTD | PMID:19822182 | sulfadimethoxine | increases expression | EXP | | 6480464 | Sulfadimethoxine results in increased expression of RAE1 mRNA | CTD | PMID:30047161 | sulforaphane | multiple interactions | ISO | Rae1 (Mus musculus) | 6480464 | [sulforaphane affects the susceptibility to Oxygen] which affects the expression of RAE1 mRNA | CTD | PMID:30529165 | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of RAE1 mRNA | CTD | PMID:31150632 | tetrachloromethane | increases expression | ISO | Rae1 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of RAE1 mRNA | CTD | PMID:31919559 | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of RAE1 mRNA] | CTD | PMID:31150632 | tremolite asbestos | increases expression | ISO | Rae1 (Mus musculus) | 6480464 | tremolite results in increased expression of RAE1 mRNA | CTD | PMID:29279043 | urethane | increases expression | ISO | RAE1 (Homo sapiens) | 6480464 | Urethane results in increased expression of RAE1 mRNA | CTD | PMID:28818685 | valproic acid | affects expression | ISO | Rae1 (Mus musculus) | 6480464 | Valproic Acid affects the expression of RAE1 mRNA | CTD | PMID:17292431 | valproic acid | affects expression | ISO | RAE1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of RAE1 mRNA | CTD | PMID:25979313 | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of RAE1 mRNA | CTD | PMID:23034163 | |