Lpin3 (lipin 3) - Rat Genome Database

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Gene: Lpin3 (lipin 3) Rattus norvegicus
Analyze
Symbol: Lpin3
Name: lipin 3
RGD ID: 1588534
Description: Predicted to enable phosphatidate phosphatase activity and transcription coactivator activity. Predicted to be involved in several processes, including cellular response to insulin stimulus; fatty acid catabolic process; and triglyceride biosynthetic process. Predicted to be active in nucleus. Orthologous to human LPIN3 (lipin 3); INTERACTS WITH 6-propyl-2-thiouracil; amphetamine; azoxystrobin.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC362261; MGC109016; phosphatidate phosphatase LPIN3; similar to lipin 3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23149,533,719 - 149,558,494 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3149,534,051 - 149,558,327 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3153,358,261 - 153,371,255 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.03161,857,652 - 161,870,646 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.03159,597,498 - 159,610,482 (+)NCBIRnor_WKY
Rnor_6.03156,874,805 - 156,899,601 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3156,886,454 - 156,899,436 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03163,102,102 - 163,126,692 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43151,689,960 - 151,702,944 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera3148,217,925 - 148,230,909 (+)NCBICelera
Cytogenetic Map3q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleus  (IBA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:17158099   PMID:18694939   PMID:23505321  


Genomics

Comparative Map Data
Lpin3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23149,533,719 - 149,558,494 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3149,534,051 - 149,558,327 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3153,358,261 - 153,371,255 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.03161,857,652 - 161,870,646 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.03159,597,498 - 159,610,482 (+)NCBIRnor_WKY
Rnor_6.03156,874,805 - 156,899,601 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3156,886,454 - 156,899,436 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03163,102,102 - 163,126,692 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43151,689,960 - 151,702,944 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera3148,217,925 - 148,230,909 (+)NCBICelera
Cytogenetic Map3q42NCBI
LPIN3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382041,340,821 - 41,360,582 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl2041,340,821 - 41,360,582 (+)EnsemblGRCh38hg38GRCh38
GRCh372039,969,461 - 39,989,222 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362039,402,974 - 39,422,636 (+)NCBINCBI36Build 36hg18NCBI36
Celera2036,680,226 - 36,699,888 (+)NCBICelera
Cytogenetic Map20q12NCBI
HuRef2036,707,814 - 36,727,419 (+)NCBIHuRef
CHM1_12039,873,839 - 39,893,508 (+)NCBICHM1_1
T2T-CHM13v2.02043,072,664 - 43,092,380 (+)NCBIT2T-CHM13v2.0
Lpin3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392160,722,590 - 160,747,920 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2160,722,590 - 160,747,922 (+)EnsemblGRCm39 Ensembl
GRCm382160,880,670 - 160,906,000 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2160,880,670 - 160,906,002 (+)EnsemblGRCm38mm10GRCm38
MGSCv372160,706,469 - 160,731,528 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362160,572,174 - 160,597,233 (+)NCBIMGSCv36mm8
Celera2166,811,402 - 166,836,437 (+)NCBICelera
Cytogenetic Map2H2NCBI
Lpin3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544515,596,832 - 15,615,900 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544515,600,510 - 15,616,452 (-)NCBIChiLan1.0ChiLan1.0
LPIN3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12038,778,785 - 38,798,502 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2038,778,695 - 38,798,502 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02037,682,636 - 37,702,357 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
LPIN3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12429,343,658 - 29,360,472 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2429,347,627 - 29,399,854 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2428,988,938 - 29,005,758 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02430,048,503 - 30,065,326 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2430,048,549 - 30,065,326 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12429,317,348 - 29,334,163 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02429,420,824 - 29,437,634 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02429,917,336 - 29,934,167 (+)NCBIUU_Cfam_GSD_1.0
Lpin3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640178,301,812 - 178,318,993 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936561430,491 - 443,307 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LPIN3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1743,989,333 - 44,006,262 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11743,993,710 - 44,006,188 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21749,433,516 - 49,450,557 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LPIN3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1222,412,858 - 22,432,563 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl222,410,294 - 22,424,587 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605071,231,337 - 71,250,938 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lpin3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479012,895,047 - 12,906,700 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479012,893,588 - 12,910,921 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Position Markers
RH134062  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23149,557,944 - 149,558,163 (+)MAPPERmRatBN7.2
Rnor_6.03156,899,052 - 156,899,270NCBIRnor6.0
Rnor_5.03163,126,143 - 163,126,361UniSTSRnor5.0
RGSC_v3.43151,702,558 - 151,702,776UniSTSRGSC3.4
Celera3148,230,523 - 148,230,741UniSTS
RH 3.4 Map31369.1UniSTS
Cytogenetic Map3q42UniSTS
MARC_23321-23322:1024689677:5  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23149,556,395 - 149,556,907 (+)MAPPERmRatBN7.2
Rnor_6.03156,897,503 - 156,898,014NCBIRnor6.0
Rnor_5.03163,124,594 - 163,125,105UniSTSRnor5.0
RGSC_v3.43151,701,009 - 151,701,520UniSTSRGSC3.4
Celera3148,228,974 - 148,229,485UniSTS
Cytogenetic Map3q42UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
1581568Rf53Renal function QTL 53total urine protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)394856903159898684Rat
2312659Slep7Serum leptin concentration QTL 70.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)398535255168026850Rat
2312670Bw94Body weight QTL 940.01inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)398535255168026850Rat
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
619618Rf3Renal disease susceptibility QTL 36.50.001urine albumin amount (VT:0002871)urine albumin excretion rate to body weight ratio (CMO:0001270)3107693393152693393Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3112681431157681431Rat
1576306Schws3Schwannoma susceptibility QTL 30.001nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)3118839124163839124Rat
1598877Bp285Blood pressure QTL 2851.50.03arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3120538241165538241Rat
1300159Kidm4Kidney mass QTL 43.83kidney mass (VT:0002707)right kidney wet weight to body weight ratio (CMO:0001953)3121056165157309487Rat
10755461Coatc16Coat color QTL 16coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)3122438700167438700Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3124122556169034231Rat
2303620Vencon4Ventilatory control QTL 43.9respiration trait (VT:0001943)tidal volume (CMO:0000222)3127162703168026850Rat
631673Iddm13Insulin dependent diabetes mellitus QTL 131.30.663blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)3130193298161695983Rat
1578656Vnigr2Vascular neointimal growth QTL 24.2artery morphology trait (VT:0002191)lesioned artery residual lumen area (CMO:0001417)3130656562169034231Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3130656562169034231Rat
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3131635904169034231Rat
2298477Eau4Experimental allergic uveoretinitis QTL 40.0011uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)3137398739169034231Rat
8552952Pigfal13Plasma insulin-like growth factor 1 level QTL 13blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)3138799500169034231Rat
1298068Bp167Blood pressure QTL 1670.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3141074471169034231Rat
1331726Bp208Blood pressure QTL 2083.129arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3141339013162184794Rat
61335Bp20Blood pressure QTL 203arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3141339236155617360Rat
2317883Alcrsp26Alcohol response QTL 261.80.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)3145526770169034231Rat
12879871Am7Aortic mass QTL 70.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)3145925360166177555Rat
12879872Cm97Cardiac mass QTL 970.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3145925360166177555Rat
12879873Cm96Cardiac mass QTL 960.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)3145925360166177555Rat
12879874Cm98Cardiac mass QTL 980.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)3145925360166177555Rat
12879875Kidm64Kidney mass QTL 640.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3145925360166177555Rat
12879876Bw182Body weight QTL 1820.003body mass (VT:0001259)body weight (CMO:0000012)3145925360166177555Rat
2301411Bp320Blood pressure QTL 3200.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3145925360166177555Rat
1300113Bp176Blood pressure QTL 1763.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3145956084157309487Rat
1598854Memor10Memory QTL 102exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)3145956084161299569Rat
8552791Vie2Viral induced encephalitis QTL 24.1brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)3145956084169034231Rat
1578666Vnigr1Vascular neointimal growth QTL 14.6artery morphology trait (VT:0002191)artery lumen area (CMO:0001409)3149040888168026850Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:377
Count of miRNA genes:223
Interacting mature miRNAs:256
Transcripts:ENSRNOT00000022403
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 13 5 4 5 3 29 32 11
Low 43 44 36 15 36 8 11 71 6 9 8
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001014184 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006235487 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006235489 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006235490 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006235491 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006235493 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006235494 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591931 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591932 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105514 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105515 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105516 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105517 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105518 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105520 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105521 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039105522 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC128986 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC089878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000120 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000022403   ⟹   ENSRNOP00000022403
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3149,534,051 - 149,558,327 (+)Ensembl
Rnor_6.0 Ensembl3156,886,454 - 156,899,436 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000095845   ⟹   ENSRNOP00000096250
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3149,534,051 - 149,558,327 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000111332   ⟹   ENSRNOP00000081644
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3149,534,051 - 149,558,327 (+)Ensembl
RefSeq Acc Id: NM_001014184   ⟹   NP_001014206
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23149,545,347 - 149,558,331 (+)NCBI
Rnor_6.03156,886,454 - 156,899,438 (+)NCBI
Rnor_5.03163,102,102 - 163,126,692 (+)NCBI
RGSC_v3.43151,689,960 - 151,702,944 (+)RGD
Celera3148,217,925 - 148,230,909 (+)RGD
Sequence:
RefSeq Acc Id: XM_006235487   ⟹   XP_006235549
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23149,540,638 - 149,558,334 (+)NCBI
Rnor_6.03156,881,729 - 156,899,601 (+)NCBI
Rnor_5.03163,102,102 - 163,126,692 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006235493   ⟹   XP_006235555
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23149,533,726 - 149,558,334 (+)NCBI
Rnor_6.03156,874,805 - 156,899,601 (+)NCBI
Rnor_5.03163,102,102 - 163,126,692 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039105514   ⟹   XP_038961442
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23149,540,630 - 149,558,494 (+)NCBI
RefSeq Acc Id: XM_039105515   ⟹   XP_038961443
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23149,533,719 - 149,558,494 (+)NCBI
RefSeq Acc Id: XM_039105516   ⟹   XP_038961444
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23149,540,630 - 149,558,494 (+)NCBI
RefSeq Acc Id: XM_039105517   ⟹   XP_038961445
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23149,537,457 - 149,558,494 (+)NCBI
RefSeq Acc Id: XM_039105518   ⟹   XP_038961446
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23149,540,630 - 149,558,494 (+)NCBI
RefSeq Acc Id: XM_039105519   ⟹   XP_038961447
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23149,533,719 - 149,558,494 (+)NCBI
RefSeq Acc Id: XM_039105520   ⟹   XP_038961448
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23149,540,630 - 149,558,494 (+)NCBI
RefSeq Acc Id: XM_039105521   ⟹   XP_038961449
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23149,533,719 - 149,558,494 (+)NCBI
RefSeq Acc Id: XM_039105522   ⟹   XP_038961450
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23149,540,630 - 149,558,494 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_001014206   ⟸   NM_001014184
- UniProtKB: Q5EBA5 (UniProtKB/TrEMBL),   F1LMI0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006235555   ⟸   XM_006235493
- Peptide Label: isoform X2
- UniProtKB: Q5EBA5 (UniProtKB/TrEMBL),   F1LMI0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006235549   ⟸   XM_006235487
- Peptide Label: isoform X2
- UniProtKB: Q5EBA5 (UniProtKB/TrEMBL),   F1LMI0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000022403   ⟸   ENSRNOT00000022403
RefSeq Acc Id: XP_038961443   ⟸   XM_039105515
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038961447   ⟸   XM_039105519
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038961449   ⟸   XM_039105521
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038961445   ⟸   XM_039105517
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038961444   ⟸   XM_039105516
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038961448   ⟸   XM_039105520
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038961442   ⟸   XM_039105514
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038961446   ⟸   XM_039105518
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038961450   ⟸   XM_039105522
- Peptide Label: isoform X1
RefSeq Acc Id: ENSRNOP00000081644   ⟸   ENSRNOT00000111332
RefSeq Acc Id: ENSRNOP00000096250   ⟸   ENSRNOT00000095845
Protein Domains
LNS2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5EBA5-F1-model_v2 AlphaFold Q5EBA5 1-844 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
Damaging Variants


Assembly: Rnor_5.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
3 163116521 163116522 A G snv LE/OrlBarth (UDEL)
3 163125388 163125389 T C snv DOB/Oda (KyushuU)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1588534 AgrOrtholog
BioCyc Gene G2FUF-46964 BioCyc
BioCyc Pathway PWY-7782 [plasmalogen biosynthesis] BioCyc
  PWY-8052 [2-arachidonoylglycerol biosynthesis] BioCyc
  PWY-8053 [anandamide biosynthesis II] BioCyc
  TRIGLSYN-PWY [diacylglycerol and triacylglycerol biosynthesis] BioCyc
Ensembl Genes ENSRNOG00000016636 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000022403.6 UniProtKB/TrEMBL
  ENSRNOP00000081644.1 UniProtKB/TrEMBL
  ENSRNOP00000096250 ENTREZGENE
  ENSRNOP00000096250.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000022403.6 UniProtKB/TrEMBL
  ENSRNOT00000095845 ENTREZGENE
  ENSRNOT00000095845.1 UniProtKB/TrEMBL
  ENSRNOT00000111332.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1000 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7326188 IMAGE-MGC_LOAD
InterPro HAD-like_sf UniProtKB/TrEMBL
  HAD_sf UniProtKB/TrEMBL
  LIPIN UniProtKB/TrEMBL
  Lipin_mid UniProtKB/TrEMBL
  Lipin_N UniProtKB/TrEMBL
  LNS2 UniProtKB/TrEMBL
  LNS2/PITP UniProtKB/TrEMBL
KEGG Report rno:362261 UniProtKB/TrEMBL
MGC_CLONE MGC:109016 IMAGE-MGC_LOAD
NCBI Gene 362261 ENTREZGENE
PANTHER PTHR12181 UniProtKB/TrEMBL
Pfam Lipin_mid UniProtKB/TrEMBL
  Lipin_N UniProtKB/TrEMBL
  LNS2 UniProtKB/TrEMBL
PhenoGen Lpin3 PhenoGen
SMART LNS2 UniProtKB/TrEMBL
Superfamily-SCOP HAD-like_dom UniProtKB/TrEMBL
UniProt A0A8I6AUU1_RAT UniProtKB/TrEMBL
  A0A8I6G885_RAT UniProtKB/TrEMBL
  A0A8J8YGA4_RAT UniProtKB/TrEMBL
  F1LMI0 ENTREZGENE
  Q5EBA5 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary F1LMI0 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-05 Lpin3  lipin 3  LOC362261  similar to lipin 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-19 LOC362261  similar to lipin 3      Symbol and Name status set to provisional 70820 PROVISIONAL