Plcg1 (phospholipase C, gamma 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Plcg1 (phospholipase C, gamma 1) Rattus norvegicus
Analyze
Symbol: Plcg1
Name: phospholipase C, gamma 1
RGD ID: 3347
Description: Exhibits insulin receptor binding activity; phospholipase C activity; and phosphoprotein binding activity. Involved in several processes, including inositol trisphosphate biosynthetic process; regulation of store-operated calcium channel activity; and response to morphine. Localizes to clathrin-coated vesicle. Colocalizes with neuron projection. Orthologous to human PLCG1 (phospholipase C gamma 1); PARTICIPATES IN E-cadherin signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; epidermal growth factor/neuregulin signaling pathway; INTERACTS WITH (+)-dihydromyricetin; (+)-schisandrin B; (R)-noradrenaline.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1; phosphoinositide phospholipase C; phosphoinositide phospholipase C-gamma-1; phospholipase C-gamma-1; PLC-148; PLC-gamma-1; PLC-II; PPLCA
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23149,385,587 - 149,416,330 (+)NCBI
Rnor_6.0 Ensembl3156,727,642 - 156,758,307 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.03156,727,642 - 156,758,307 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03162,957,126 - 162,987,842 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43151,522,949 - 151,553,998 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13151,428,984 - 151,460,034 (+)NCBI
Celera3148,059,477 - 148,090,220 (+)NCBICelera
RH 3.4 Map31368.6RGD
Cytogenetic Map3q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-dihydromyricetin  (EXP)
(+)-schisandrin B  (EXP)
(R)-noradrenaline  (EXP)
(S)-nicotine  (EXP)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,6-dinitrotoluene  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
5-fluorouracil  (ISO)
acetaldehyde  (ISO)
acrylonitrile  (EXP)
aflatoxin B1  (ISO)
amiodarone  (EXP)
ammonium chloride  (EXP)
amphetamine  (EXP)
ANTIMYCIN  (ISO)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
asbestos  (ISO)
auramine O  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
bisphenol A  (EXP,ISO)
Brodifacoum  (EXP)
cadmium dichloride  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
carbonyl cyanide p-trifluoromethoxyphenylhydrazone  (ISO)
choline  (ISO)
chrysin  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
cobalt dichloride  (ISO)
cocaine  (EXP)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
Deguelin  (ISO)
dexamethasone  (ISO)
dibenz[a,h]anthracene  (ISO)
diclofenac  (ISO)
dicrotophos  (ISO)
dioxygen  (EXP,ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
Evodiamine  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
genistein  (EXP)
ginsenoside Rg1  (ISO)
Heptachlor epoxide  (ISO)
hydralazine  (ISO)
hydrogen peroxide  (ISO)
imipramine  (ISO)
L-methionine  (ISO)
lipopolysaccharide  (ISO)
melittin  (EXP)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
methylmercury(1+)  (ISO)
monosodium L-glutamate  (ISO)
N-acetylsphingosine  (ISO)
N-nitrosodiethylamine  (EXP)
nicotine  (EXP)
ochratoxin A  (ISO)
ouabain  (ISO)
ozone  (EXP)
paracetamol  (ISO)
paraquat  (EXP)
PCB138  (ISO)
phenethyl caffeate  (EXP)
phenformin  (ISO)
phenylarsine oxide  (EXP,ISO)
phenylephrine  (EXP)
platycodin D  (ISO)
potassium dichromate  (ISO)
prazosin  (EXP)
pregnenolone 16alpha-carbonitrile  (ISO)
procaine  (ISO)
quercetin  (ISO)
resveratrol  (EXP,ISO)
sodium arsenite  (ISO)
sulindac  (EXP)
tetrachloromethane  (EXP)
tetracycline  (ISO)
thimerosal  (ISO)
triadimefon  (ISO)
tributylstannane  (ISO)
triptonide  (ISO)
tungsten  (ISO)
U-73122  (EXP)
urethane  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
1. Arteaga CL, etal., Proc Natl Acad Sci U S A. 1991 Dec 1;88(23):10435-9.
2. Asemu G, etal., Arch Biochem Biophys 2003 Mar 15;411(2):174-82.
3. Bae JH, etal., Cell. 2009 Aug 7;138(3):514-24. doi: 10.1016/j.cell.2009.05.028.
4. Birchmeier C, etal., Nat Rev Mol Cell Biol. 2003 Dec;4(12):915-25.
5. Chang JS, etal., J Biol Chem 2002 May 31;277(22):19697-702.
6. Choi JH, etal., Nat Cell Biol. 2006 Dec;8(12):1389-97. Epub 2006 Nov 26.
7. Cuozzo FP, etal., Biochim Biophys Acta 2002 May 21;1587(1):99-106.
8. Di Fruscio M, etal., Proc Natl Acad Sci U S A 1999 Mar 16;96(6):2710-5.
9. Duchene J, etal., Biochem Biophys Res Commun. 2005 Jan 28;326(4):894-900.
10. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
11. Gentile A, etal., Cancer Metastasis Rev. 2008 Mar;27(1):85-94.
12. GOA data from the GO Consortium
13. Han SJ, etal., Biochem Biophys Res Commun 2002 Jan 11;290(1):35-41.
14. Han SJ, etal., Biochem Biophys Res Commun 2003 Jan 17;300(3):649-55.
15. Han SJ, etal., Cell Biol Int. 2004;28(12):943-8.
16. He Z, etal., J Neurosci. 2012 Jul 4;32(27):9383-95. doi: 10.1523/JNEUROSCI.6363-11.2012.
17. Holmes K, etal., Cell Signal. 2007 Oct;19(10):2003-12. Epub 2007 Jun 12.
18. Jiang Y, etal., Int J Clin Exp Pathol. 2015 Aug 1;8(8):9042-51. eCollection 2015.
19. KEGG
20. Kim MJ, etal., Biochemistry. 2000 Jul 25;39(29):8674-82.
21. Kim SK, etal., Exp Mol Med. 2006 Jun 30;38(3):265-72.
22. Kim SS, etal., Exp Mol Med 2002 Mar 31;34(1):53-9.
23. Kimura T, etal., J Biol Chem. 1996 Nov 1;271(44):27962-8.
24. Koblan KS, etal., Biochem J. 1995 Feb 1;305 ( Pt 3):745-51. doi: 10.1042/bj3050745.
25. Kumei Y, etal., Ann N Y Acad Sci. 2007 Jan;1095:292-9.
26. Kwitek AE, etal., Genome Res. 2004 Apr;14(4):750-7
27. Kwon YK, etal., J Cell Biol 2003 Oct 27;163(2):375-84. Epub 2003 Oct 20.
28. Liao HJ, etal., J Biol Chem 2002 Mar 15;277(11):9335-41. Epub 2001 Dec 13.
29. Lin D, etal., Curr Eye Res. 2007 Jun;32(6):523-32.
30. Litjens T, etal., Biochem J. 2007 Jul 15;405(2):269-76.
31. Lundby A, etal., Cell. 2019 Oct 3;179(2):543-560.e26. doi: 10.1016/j.cell.2019.09.008.
32. MGD data from the GO Consortium
33. Nagasawa K, etal., Life Sci 2003 Aug 1;73(11):1453-62.
34. NCBI rat LocusLink and RefSeq merged data July 26, 2002
35. Noh DY, etal., Anticancer Res. 1998 Jul-Aug;18(4A):2643-8.
36. Patterson RL, etal., Cell 2002 Nov 15;111(4):529-41.
37. Pipeline to import KEGG annotations from KEGG into RGD
38. Pipeline to import Pathway Interaction Database annotations from NCI into RGD
39. Pipeline to import SMPDB annotations from SMPDB into RGD
40. Rao JN, etal., Am J Physiol Gastrointest Liver Physiol. 2007 Jan;292(1):G335-43. Epub 2006 Sep 14.
41. Readinger JA, etal., Proc Natl Acad Sci U S A. 2008 May 6;105(18):6684-9. doi: 10.1073/pnas.0709659105. Epub 2008 Apr 28.
42. RGD automated data pipeline
43. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
44. RGD automated import pipeline for gene-chemical interactions
45. Shimohama S and Matsushima H, Alzheimer Dis Assoc Disord. 1995;9 Suppl 2:15-22.
46. Song M, etal., Exp Mol Med. 2005 Jun 30;37(3):161-8.
47. Suh PG, etal., Proc Natl Acad Sci U S A 1988 Aug;85(15):5419-23.
48. Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
49. van Rossum DB, etal., Nature. 2005 Mar 3;434(7029):99-104.
50. Varela D, etal., Cell Physiol Biochem. 2007;20(6):773-80.
51. Wolf DH, etal., Brain Res. 2007 Jul 2;1156:9-20. Epub 2007 May 4.
52. Ye K, etal., Nature. 2002 Jan 31;415(6871):541-4.
Additional References at PubMed
PMID:2550068   PMID:8106527   PMID:8183574   PMID:8392838   PMID:8402898   PMID:8615781   PMID:11724770   PMID:12367511   PMID:12646582   PMID:12930795   PMID:14523024   PMID:14570902  
PMID:15161916   PMID:15169852   PMID:15252117   PMID:15258148   PMID:15488758   PMID:15536495   PMID:15579910   PMID:15607032   PMID:15702972   PMID:15728238   PMID:15865439   PMID:16038803  
PMID:16321979   PMID:16710293   PMID:16841466   PMID:16867273   PMID:16989733   PMID:17196935   PMID:17229814   PMID:17252537   PMID:17355934   PMID:17618160   PMID:18579528   PMID:18616564  
PMID:19179337   PMID:19208792   PMID:19505325   PMID:19538471   PMID:19605547   PMID:19717566   PMID:20011604   PMID:20164676   PMID:20807769   PMID:21210726   PMID:21360263   PMID:22390417  
PMID:22454520   PMID:22561606   PMID:22890232   PMID:23793062   PMID:24785188   PMID:25175053   PMID:26037503   PMID:26687682   PMID:27306412   PMID:27464494   PMID:27484337   PMID:28100486  
PMID:28138157   PMID:28698260   PMID:32868075  


Genomics

Comparative Map Data
Plcg1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23149,385,587 - 149,416,330 (+)NCBI
Rnor_6.0 Ensembl3156,727,642 - 156,758,307 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.03156,727,642 - 156,758,307 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03162,957,126 - 162,987,842 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43151,522,949 - 151,553,998 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13151,428,984 - 151,460,034 (+)NCBI
Celera3148,059,477 - 148,090,220 (+)NCBICelera
RH 3.4 Map31368.6RGD
Cytogenetic Map3q42NCBI
PLCG1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2041,136,960 - 41,196,801 (+)EnsemblGRCh38hg38GRCh38
GRCh382041,137,519 - 41,177,626 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372039,766,183 - 39,806,266 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362039,199,575 - 39,237,771 (+)NCBINCBI36hg18NCBI36
Build 342039,199,574 - 39,237,771NCBI
Celera2036,476,730 - 36,514,924 (+)NCBI
Cytogenetic Map20q12NCBI
HuRef2036,504,215 - 36,542,409 (+)NCBIHuRef
CHM1_12039,670,573 - 39,708,755 (+)NCBICHM1_1
Plcg1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392160,573,230 - 160,617,680 (+)NCBIGRCm39mm39
GRCm39 Ensembl2160,573,220 - 160,617,680 (+)Ensembl
GRCm382160,731,310 - 160,775,760 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2160,731,300 - 160,775,760 (+)EnsemblGRCm38mm10GRCm38
MGSCv372160,557,046 - 160,601,496 (+)NCBIGRCm37mm9NCBIm37
MGSCv362160,422,751 - 160,467,201 (+)NCBImm8
Celera2166,663,373 - 166,707,819 (+)NCBICelera
Cytogenetic Map2H2NCBI
cM Map280.97NCBI
Plcg1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544515,787,496 - 15,823,859 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544515,787,496 - 15,823,859 (-)NCBIChiLan1.0ChiLan1.0
PLCG1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12038,577,199 - 38,615,149 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2038,572,709 - 38,615,145 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02037,477,077 - 37,515,854 (+)NCBIMhudiblu_PPA_v0panPan3
PLCG1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12429,198,536 - 29,213,899 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2429,198,556 - 29,214,714 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2428,823,106 - 28,859,401 (+)NCBI
ROS_Cfam_1.02429,883,241 - 29,919,530 (+)NCBI
UMICH_Zoey_3.12429,152,120 - 29,188,420 (+)NCBI
UNSW_CanFamBas_1.02429,256,001 - 29,292,271 (+)NCBI
UU_Cfam_GSD_1.02429,752,157 - 29,788,483 (+)NCBI
Plcg1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640178,117,909 - 178,150,680 (+)NCBI
SpeTri2.0NW_004936561598,372 - 631,575 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLCG1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1743,809,677 - 43,844,555 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11743,810,003 - 43,844,553 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21749,203,540 - 49,238,416 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PLCG1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1222,599,547 - 22,638,394 (-)NCBI
Plcg1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249191,766,533 - 1,800,130 (+)NCBI

Position Markers
Plcg1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.03156,754,792 - 156,754,943NCBIRnor6.0
Rnor_5.03162,984,327 - 162,984,478UniSTSRnor5.0
RGSC_v3.43151,550,483 - 151,550,634UniSTSRGSC3.4
Celera3148,086,703 - 148,086,854UniSTS
Cytogenetic Map3q42UniSTS
RH94494  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.03156,757,172 - 156,757,349NCBIRnor6.0
Rnor_5.03162,986,707 - 162,986,884UniSTSRnor5.0
RGSC_v3.43151,552,863 - 151,553,040UniSTSRGSC3.4
Celera3148,089,083 - 148,089,260UniSTS
RH 3.4 Map31368.6UniSTS
Cytogenetic Map3q42UniSTS
ksks435  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.03156,756,329 - 156,756,610NCBIRnor6.0
Rnor_5.03162,985,864 - 162,986,145UniSTSRnor5.0
RGSC_v3.43151,552,020 - 151,552,301UniSTSRGSC3.4
Celera3148,088,240 - 148,088,521UniSTS
Cytogenetic Map3q42UniSTS
PMC20311P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.03156,746,935 - 156,747,283NCBIRnor6.0
Rnor_5.03162,976,470 - 162,976,818UniSTSRnor5.0
RGSC_v3.43151,542,626 - 151,542,974UniSTSRGSC3.4
Celera3148,078,846 - 148,079,194UniSTS
Cytogenetic Map3q42UniSTS
Plcg1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.03156,754,550 - 156,754,794NCBIRnor6.0
Rnor_5.03162,984,085 - 162,984,329UniSTSRnor5.0
Celera3148,086,461 - 148,086,705UniSTS
Cytogenetic Map3q42UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)330846101172879276Rat
619618Rf3Renal disease susceptibility QTL 36.50.001urine albumin amount (VT:0002871)urine albumin excretion rate to body weight ratio (CMO:0001270)3114376250159376250Rat
1578656Vnigr2Vascular neointimal growth QTL 24.2artery morphology trait (VT:0002191)lesioned artery residual lumen area (CMO:0001417)3138374177177699992Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)345406058177699992Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)3103141944170934860Rat
1331726Bp208Blood pressure QTL 2083.129arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3148348517171467264Rat
1298068Bp167Blood pressure QTL 1670.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3150368003177699992Rat
631673Iddm13Insulin dependent diabetes mellitus QTL 131.30.663blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)3136876155170935007Rat
2312659Slep7Serum leptin concentration QTL 70.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)3103141814176418101Rat
2312670Bw94Body weight QTL 940.01inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)3103141814176418101Rat
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)3103141814176418101Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3138374177177699992Rat
2317883Alcrsp26Alcohol response QTL 261.80.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)3153918022177699992Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3129787213177699992Rat
1581568Rf53Renal function QTL 53total urine protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)358204463170534769Rat
1598854Memor10Memory QTL 102exploratory behavior trait (VT:0010471)average horizontal distance in proximity to the target during voluntary locomotion in an experimental apparatus (CMO:0002674)3153412455170534769Rat
1598877Bp285Blood pressure QTL 2851.50.03arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3128986468173986468Rat
2298477Eau4Experimental allergic uveoretinitis QTL 40.0011uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)3146232777177699992Rat
2301411Bp320Blood pressure QTL 3200.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3153381237174632112Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)399465522168732722Rat
1576306Schws3Schwannoma susceptibility QTL 30.001nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)3125848628170848628Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3119471263164471263Rat
1578666Vnigr1Vascular neointimal growth QTL 14.6artery morphology trait (VT:0002191)artery lumen area (CMO:0001409)3156381661176418101Rat
1300113Bp176Blood pressure QTL 1763.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3153412455165355668Rat
1300159Kidm4Kidney mass QTL 43.83kidney mass (VT:0002707)right kidney wet weight to body weight ratio (CMO:0001953)3126575595165355668Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)343295930163640485Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)343295930163640485Rat
2303620Vencon4Ventilatory control QTL 43.9respiration trait (VT:0001943)tidal volume (CMO:0000222)3132875075176418101Rat
61335Bp20Blood pressure QTL 203arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3148348739163640325Rat
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3139578365177699992Rat
8552791Vie2Viral induced encephalitis QTL 24.1brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)3153412455177699992Rat
8552952Pigfal13Plasma insulin-like growth factor 1 level QTL 13blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)3148034701177699992Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)361241033165369047Rat
12879874Cm98Cardiac mass QTL 980.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)3153381237174632112Rat
12879875Kidm64Kidney mass QTL 640.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3153381237174632112Rat
10755461Coatc16Coat color QTL 16coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)3130006659175006659Rat
12879871Am7Aortic mass QTL 70.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)3153381237174632112Rat
12879872Cm97Cardiac mass QTL 970.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3153381237174632112Rat
12879873Cm96Cardiac mass QTL 960.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)3153381237174632112Rat
12879876Bw182Body weight QTL 1820.003body mass (VT:0001259)body weight (CMO:0000012)3153381237174632112Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:556
Count of miRNA genes:256
Interacting mature miRNAs:331
Transcripts:ENSRNOT00000022276
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 52 36 19 36 2 5 74 35 41 11 2
Low 5 5 5 6 6 6
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000078909   ⟹   ENSRNOP00000069822
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl3156,727,642 - 156,758,307 (+)Ensembl
RefSeq Acc Id: NM_013187   ⟹   NP_037319
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23149,385,587 - 149,416,330 (+)NCBI
Rnor_6.03156,727,642 - 156,758,307 (+)NCBI
Rnor_5.03162,957,126 - 162,987,842 (+)NCBI
RGSC_v3.43151,522,949 - 151,553,998 (+)RGD
Celera3148,059,477 - 148,090,220 (+)RGD
Sequence:
RefSeq Acc Id: XM_039104387   ⟹   XP_038960315
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23149,385,645 - 149,414,681 (+)NCBI
Protein Sequences
Protein RefSeqs NP_037319 (Get FASTA)   NCBI Sequence Viewer  
  XP_038960315 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA41921 (Get FASTA)   NCBI Sequence Viewer  
  EDL96614 (Get FASTA)   NCBI Sequence Viewer  
  EDL96615 (Get FASTA)   NCBI Sequence Viewer  
  P10686 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_037319   ⟸   NM_013187
- Sequence:
RefSeq Acc Id: ENSRNOP00000069822   ⟸   ENSRNOT00000078909
RefSeq Acc Id: XP_038960315   ⟸   XM_039104387
- Peptide Label: isoform X1
Protein Domains
C2   EF-hand   PH   PI-PLC X-box   PI-PLC Y-box   SH2   SH3

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Damaging Variants


Assembly: Rnor_5.0

Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
3 162975830 162975831 C T snv DOB/Oda (KyushuU)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3347 AgrOrtholog
Ensembl Genes ENSRNOG00000051490 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000069822 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000078909 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.40.150 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.20.20.190 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.505.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro C2_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF-hand-dom_pair UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI-PLC_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLC-gamma UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLC-gamma1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLC-gamma_C-SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLC-gamma_N-SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLC-like_Pdiesterase_TIM-brl UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLCgamma1_SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLipase_C_PInositol-sp_X_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLipase_C_Pinositol-sp_Y UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH2_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:25738 UniProtKB/Swiss-Prot
NCBI Gene 25738 ENTREZGENE
PANTHER PTHR10336 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10336:SF173 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PF00168 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI-PLC-X UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PI-PLC-Y UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PLCG1 RGD
PhenoGen Plcg1 PhenoGen
PIRSF PLC-gamma UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS PHPHLIPASEC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH2DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE EF_HAND_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PIPLC_X_DOMAIN UniProtKB/Swiss-Prot
  PIPLC_Y_DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PS50004 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART PLCXc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLCYc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00233 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00239 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF50044 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF51695 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF55550 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC216671
UniProt G3V845_RAT UniProtKB/TrEMBL
  P10686 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Plcg1  Phospholipase C, gamma 1      Symbol and Name status set to approved 70586 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_physical_interaction binds to SOS1, a p21 Ras-specific guanine nucleotide exchange factor, through its SH3 domain 729542
gene_physical_interaction protein interacts with Vdp, vesicle docking protein, through its SH2 and SH3 domains 734467
gene_process plays role in vesicle transport via its interaction with Vdp (vesicle docking protein) 734467
gene_regulation activated by tyrosine kinase receptors and nonreceptor tyrosine kinases 729542