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Gene: Hrh3 (histamine receptor H3) Rattus norvegicus
Symbol: Hrh3
Name: histamine receptor H3
Description: Exhibits drug binding activity and histamine receptor activity. Involved in several processes, including learning or memory; negative regulation of adenylate cyclase activity; and regulation of secretion. Localizes to myelin sheath; neuron projection; and plasma membrane. Used to study several diseases, including gastric ulcer; hyperglycemia; obesity; sciatic neuropathy; and visual epilepsy. Biomarker of status epilepticus. Orthologous to human HRH3 (histamine receptor H3); INTERACTS WITH 2-methylpyrrolidine; 3',5'-cyclic AMP; alpha-methylhistamine.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: H3R; HH3R; histamine H3 receptor; MGC105370
Homo sapiens (human) : HRH3 (histamine receptor H3)  HGNC  Alliance
Mus musculus (house mouse) : Hrh3 (histamine receptor H3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hrh3 (histamine receptor H3)
Pan paniscus (bonobo/pygmy chimpanzee) : HRH3 (histamine receptor H3)
Canis lupus familiaris (dog) : HRH3 (histamine receptor H3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hrh3 (histamine receptor H3)
Sus scrofa (pig) : HRH3 (histamine receptor H3)
Chlorocebus sabaeus (African green monkey) : HRH3 (histamine receptor H3)
Heterocephalus glaber (naked mole-rat) : Hrh3 (histamine receptor H3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.03175,474,310 - 175,479,395 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3175,473,078 - 175,479,395 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03181,639,287 - 181,644,372 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43169,154,980 - 169,160,064 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13169,061,015 - 169,066,100 (-)NCBI
Celera3165,383,487 - 165,388,550 (+)NCBICelera
Cytogenetic Map3q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Hrh3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620630
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.