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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 17alpha-ethynylestradiol | multiple interactions | ISO | RGD:1323708 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of TNNC2 mRNA | CTD | PMID:17942748 | 17beta-estradiol | affects expression | ISO | RGD:1323707 | 6480464 | Estradiol affects the expression of TNNC2 mRNA | CTD | PMID:22574217 | 17beta-estradiol | decreases expression | EXP | | 6480464 | Estradiol results in decreased expression of TNNC2 mRNA | CTD | PMID:26945725 | 17beta-estradiol | decreases expression | ISO | RGD:1323708 | 6480464 | Estradiol results in decreased expression of TNNC2 mRNA | CTD | PMID:19484750 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:1323708 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of TNNC2 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of TNNC2 mRNA | CTD | PMID:32109520 | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:32109520 | 2-hydroxypropanoic acid | decreases expression | ISO | RGD:1323707 | 6480464 | Lactic Acid results in decreased expression of TNNC2 mRNA | CTD | PMID:30851411 | 3,3',5,5'-tetrabromobisphenol A | decreases expression | EXP | | 6480464 | tetrabromobisphenol A results in decreased expression of TNNC2 mRNA | CTD | PMID:27914987 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | RGD:1323707 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of TNNC2 mRNA | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | increases expression | ISO | RGD:1323708 | 6480464 | bis(4-hydroxyphenyl)sulfone results in increased expression of TNNC2 mRNA | CTD | PMID:30951980 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of TNNC2 mRNA | CTD | PMID:24780913, PMID:25825206 | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of TNNC2 mRNA | CTD | PMID:31881176 | acrylamide | decreases expression | EXP | | 6480464 | Acrylamide results in decreased expression of TNNC2 mRNA | CTD | PMID:28606764 | aristolochic acid A | increases expression | ISO | RGD:1323707 | 6480464 | aristolochic acid I results in increased expression of TNNC2 mRNA | CTD | PMID:33212167 | arsane | decreases expression | ISO | RGD:1323708 | 6480464 | Arsenic results in decreased expression of TNNC2 mRNA | CTD | PMID:19654921 | arsane | affects methylation | ISO | RGD:1323707 | 6480464 | Arsenic affects the methylation of TNNC2 gene | CTD | PMID:25304211 | arsenic atom | decreases expression | ISO | RGD:1323708 | 6480464 | Arsenic results in decreased expression of TNNC2 mRNA | CTD | PMID:19654921 | arsenic atom | affects methylation | ISO | RGD:1323707 | 6480464 | Arsenic affects the methylation of TNNC2 gene | CTD | PMID:25304211 | benzo[a]pyrene | decreases expression | ISO | RGD:1323708 | 6480464 | Benzo(a)pyrene results in decreased expression of TNNC2 mRNA | CTD | PMID:22228805 | benzo[a]pyrene | affects methylation | ISO | RGD:1323707 | 6480464 | Benzo(a)pyrene affects the methylation of TNNC2 3' UTR | CTD | PMID:27901495 | benzo[e]pyrene | increases methylation | ISO | RGD:1323707 | 6480464 | benzo(e)pyrene results in increased methylation of TNNC2 promoter | CTD | PMID:30157460 | bis(2-ethylhexyl) phthalate | increases expression | ISO | RGD:1323708 | 6480464 | Diethylhexyl Phthalate results in increased expression of TNNC2 mRNA | CTD | PMID:28085963 | bisphenol A | affects expression | ISO | RGD:1323708 | 6480464 | bisphenol A affects the expression of TNNC2 mRNA | CTD | PMID:14967926 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of TNNC2 mRNA | CTD | PMID:30903817 | bisphenol A | multiple interactions | ISO | RGD:1323707 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of TNNC2 mRNA | CTD | PMID:28628672 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of TNNC2 mRNA | CTD | PMID:25181051 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of TNNC2 mRNA | CTD | PMID:24134786 | bisphenol F | increases expression | ISO | RGD:1323708 | 6480464 | bisphenol F results in increased expression of TNNC2 mRNA | CTD | PMID:30951980 | bromobenzene | increases expression | EXP | | 6480464 | bromobenzene results in increased expression of TNNC2 mRNA | CTD | PMID:32479839 | carbamazepine | affects expression | ISO | RGD:1323707 | 6480464 | Carbamazepine affects the expression of TNNC2 mRNA | CTD | PMID:25979313 | carbon nanotube | affects expression | ISO | RGD:1323708 | 6480464 | Nanotubes, Carbon analog affects the expression of TNNC2 mRNA | CTD | PMID:25620056 | carbon nanotube | increases expression | ISO | RGD:1323708 | 6480464 | Nanotubes, Carbon results in increased expression of TNNC2 mRNA | CTD | PMID:25620056 | chlordecone | increases expression | ISO | RGD:1323708 | 6480464 | Chlordecone results in increased expression of TNNC2 mRNA | CTD | PMID:33711761 | chrysene | increases expression | ISO | RGD:1323708 | 6480464 | chrysene results in increased expression of TNNC2 mRNA | CTD | PMID:26377693 | cisplatin | decreases expression | ISO | RGD:1323707 | 6480464 | Cisplatin results in decreased expression of TNNC2 mRNA | CTD | PMID:27392435 | cisplatin | multiple interactions | ISO | RGD:1323707 | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of TNNC2 mRNA | CTD | PMID:27392435 | copper atom | increases expression | EXP | | 6480464 | Copper results in increased expression of TNNC2 mRNA | CTD | PMID:30556269 | copper(0) | increases expression | EXP | | 6480464 | Copper results in increased expression of TNNC2 mRNA | CTD | PMID:30556269 | copper(II) sulfate | increases expression | ISO | RGD:1323707 | 6480464 | Copper Sulfate results in increased expression of TNNC2 mRNA | CTD | PMID:19549813 | Cuprizon | decreases expression | EXP | | 6480464 | Cuprizone results in decreased expression of TNNC2 mRNA | CTD | PMID:26577399, PMID:27523638 | dexamethasone | decreases expression | ISO | RGD:1323708 | 6480464 | Dexamethasone results in decreased expression of TNNC2 protein | CTD | PMID:33567340 | dexamethasone | multiple interactions | ISO | RGD:1323707 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of TNNC2 mRNA | CTD | PMID:28628672 | dextran sulfate | multiple interactions | ISO | RGD:1323708 | 6480464 | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TNNC2 mRNA | CTD | PMID:29950665 | diuron | increases expression | EXP | | 6480464 | Diuron results in increased expression of TNNC2 mRNA | CTD | PMID:21551480 | dorsomorphin | multiple interactions | ISO | RGD:1323707 | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TNNC2 mRNA | CTD | PMID:27188386 | entinostat | increases expression | ISO | RGD:1323707 | 6480464 | entinostat results in increased expression of TNNC2 mRNA | CTD | PMID:26272509 | entinostat | multiple interactions | ISO | RGD:1323707 | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TNNC2 mRNA | CTD | PMID:27188386 | genistein | decreases expression | ISO | RGD:1323708 | 6480464 | Genistein results in decreased expression of TNNC2 mRNA | CTD | PMID:32186404 | glycidol | decreases expression | EXP | | 6480464 | glycidol results in decreased expression of TNNC2 mRNA | CTD | PMID:24915197 | graphite | increases expression | ISO | RGD:1323708 | 6480464 | Graphite results in increased expression of TNNC2 mRNA | CTD | PMID:27440207 | indometacin | multiple interactions | ISO | RGD:1323707 | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of TNNC2 mRNA | CTD | PMID:28628672 | ketamine | increases expression | EXP | | 6480464 | Ketamine results in increased expression of TNNC2 mRNA | CTD | PMID:20080153 | Licochalcone B | increases expression | ISO | RGD:1323707 | 6480464 | licochalcone B results in increased expression of TNNC2 mRNA | CTD | PMID:33647349 | methapyrilene | increases methylation | ISO | RGD:1323707 | 6480464 | Methapyrilene results in increased methylation of TNNC2 promoter | CTD | PMID:30157460 | methylmercury chloride | increases expression | ISO | RGD:1323707 | 6480464 | methylmercuric chloride results in increased expression of TNNC2 mRNA | CTD | PMID:28001369 | phenobarbital | affects expression | ISO | RGD:1323708 | 6480464 | Phenobarbital affects the expression of TNNC2 mRNA | CTD | PMID:23091169 | PhIP | decreases expression | EXP | | 6480464 | 2-amino-1-methyl-6-phenylimidazo(4, 5-b)pyridine results in decreased expression of TNNC2 mRNA | CTD | PMID:29877212 | pioglitazone | multiple interactions | ISO | RGD:1323708 | 6480464 | [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TNNC2 mRNA | CTD | PMID:27935865 | progesterone | increases expression | ISO | RGD:1323708 | 6480464 | Progesterone results in increased expression of TNNC2 mRNA | CTD | PMID:22238285 | propanal | increases expression | ISO | RGD:1323707 | 6480464 | propionaldehyde results in increased expression of TNNC2 mRNA | CTD | PMID:26079696 | rac-lactic acid | decreases expression | ISO | RGD:1323707 | 6480464 | Lactic Acid results in decreased expression of TNNC2 mRNA | CTD | PMID:30851411 | resveratrol | multiple interactions | ISO | RGD:1323707 | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of TNNC2 mRNA | CTD | PMID:23557933 | SB 431542 | multiple interactions | ISO | RGD:1323707 | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TNNC2 mRNA | CTD | PMID:27188386 | sodium arsenate | increases expression | ISO | RGD:1323708 | 6480464 | sodium arsenate results in increased expression of TNNC2 mRNA | CTD | PMID:21795629 | Soman | decreases expression | EXP | | 6480464 | Soman results in decreased expression of TNNC2 mRNA | CTD | PMID:19281266 | spermine | increases expression | ISO | RGD:1323708 | 6480464 | Spermine results in increased expression of TNNC2 mRNA | CTD | PMID:18673383 | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of TNNC2 mRNA | CTD | PMID:31150632 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of TNNC2 mRNA | CTD | PMID:34492290 | titanium dioxide | increases expression | ISO | RGD:1323708 | 6480464 | titanium dioxide results in increased expression of TNNC2 mRNA | CTD | PMID:23557971 | titanium dioxide | multiple interactions | ISO | RGD:1323708 | 6480464 | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of TNNC2 mRNA | CTD | PMID:29950665 | triazines | multiple interactions | ISO | RGD:1323708 | 6480464 | Triazines inhibits the reaction [IDH2 protein mutant form results in increased expression of TNNC2 mRNA] | CTD | PMID:27469509 | triclosan | decreases expression | ISO | RGD:1323707 | 6480464 | Triclosan results in decreased expression of TNNC2 mRNA | CTD | PMID:30510588 | triptonide | increases expression | ISO | RGD:1323708 | 6480464 | triptonide results in increased expression of TNNC2 mRNA | CTD | PMID:33045310 | tunicamycin | increases expression | ISO | RGD:1323708 | 6480464 | Tunicamycin results in increased expression of TNNC2 mRNA | CTD | PMID:17127020 | urethane | decreases expression | ISO | RGD:1323707 | 6480464 | Urethane results in decreased expression of TNNC2 mRNA | CTD | PMID:28818685 | valproic acid | affects expression | ISO | RGD:1323707 | 6480464 | Valproic Acid affects the expression of TNNC2 mRNA | CTD | PMID:25979313 | valproic acid | increases expression | EXP | | 6480464 | Valproic Acid results in increased expression of TNNC2 mRNA | CTD | PMID:35594946 | |