Gene: Hnf4a (hepatocyte nuclear factor 4, alpha) Rattus norvegicus
Symbol: Hnf4a
Name: hepatocyte nuclear factor 4, alpha
Description: ENCODES a protein that exhibits arachidonic acid binding; DNA binding; DNA binding transcription factor activity; INVOLVED IN acyl-CoA metabolic process; aging; cell differentiation; PARTICIPATES IN forkhead class A signaling pathway; hypoxia inducible factor pathway; maturity onset diabetes of the young pathway; ASSOCIATED WITH Carcinoma, Hepatocellular; diabetes mellitus, experimental; Diabetic Nephropathies; FOUND IN cytoplasm; nucleus; transcription factor complex; INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: alpha transcription factor 4; hepatic nuclear factor 4; hepatic nuclear factor 4 (alpha transcription factor 4); hepatic nuclear factor 4, alpha; hepatocyte nuclear factor 4 alpha 3; hepatocyte nuclear factor 4 alpha 9; hepatocyte nuclear factor 4-alpha; HNF-4-alpha; Hnf4; Hnf4alpha; HNF4alpha10; HNF4alpha11; HNF4alpha12; nuclear receptor subfamily 2 group A member 1; TCF-14; Tcf4; transcription factor 14; transcription factor HNF-4
Homo sapiens (human) : HNF4A (hepatocyte nuclear factor 4 alpha)  HGNC  Alliance
Mus musculus (house mouse) : Hnf4a (hepatic nuclear factor 4, alpha)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hnf4a (hepatocyte nuclear factor 4 alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : HNF4A (hepatocyte nuclear factor 4 alpha)
Canis lupus familiaris (dog) : HNF4A (hepatocyte nuclear factor 4 alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hnf4a (hepatocyte nuclear factor 4 alpha)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.03159,902,441 - 159,965,003 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03166,093,091 - 166,155,667 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43154,459,863 - 154,482,825 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13154,365,898 - 154,388,861 (+)NCBI
Celera3150,839,856 - 150,901,426 (+)NCBICelera
Cytogenetic Map3q42NCBI
RH 3.4 Map31376.5RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Hnf4a
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2810
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2018-03-13
Status: ACTIVE