Gene: Slc12a5 (solute carrier family 12 member 5) Rattus norvegicus
Symbol: Slc12a5
Name: solute carrier family 12 member 5
Description: ENCODES a protein that exhibits ammonium transmembrane transporter activity; potassium:chloride symporter activity; chloride transmembrane transporter activity (ortholog); INVOLVED IN ammonium transport; chloride transport; dendritic spine development; ASSOCIATED WITH Early Infantile Epileptic Encephalopathy, 34 (ortholog); epilepsy (ortholog); Hyperalgesia (ortholog); FOUND IN dendrite membrane; perikaryon; plasma membrane; INTERACTS WITH (+)-pilocarpine; 2,4,6-trinitrotoluene; 6-propyl-2-thiouracil
Type: protein-coding
Also known as: electroneutral potassium-chloride cotransporter 2; furosemide-sensitive K-Cl cotransporter; K-Cl cotransporter 2; Kcc2; neuronal K-Cl cotransporter; neuronal-specific K-Cl cotransporter; rKCC2; solute carrier family 12 (potassium-chloride transporter), member 5; solute carrier family 12, (potassium-chloride transporter) member 5; solute carrier family 12, member 5
Homo sapiens (human) : SLC12A5 (solute carrier family 12 member 5)  HGNC  Alliance
Mus musculus (house mouse) : Slc12a5 (solute carrier family 12, member 5)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc12a5 (solute carrier family 12 member 5)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC12A5 (solute carrier family 12 member 5)
Canis lupus familiaris (dog) : SLC12A5 (solute carrier family 12 member 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc12a5 (solute carrier family 12 member 5)
Sus scrofa (pig) : SLC12A5 (solute carrier family 12 member 5)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.03161,433,303 - 161,465,078 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03167,617,776 - 167,649,551 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43156,006,017 - 156,037,915 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13155,912,052 - 155,943,951 (+)NCBI
Celera3152,309,197 - 152,341,061 (+)NCBICelera
Cytogenetic Map3q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Slc12a5
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620811
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE