Gene: Pck1 (phosphoenolpyruvate carboxykinase 1) Rattus norvegicus
Symbol: Pck1
Name: phosphoenolpyruvate carboxykinase 1
Description: ENCODES a protein that exhibits carboxylic acid binding; GDP binding; GTP binding; INVOLVED IN aging; cellular response to cAMP; cellular response to fructose stimulus; PARTICIPATES IN gluconeogenesis pathway; glycolysis/gluconeogenesis pathway; forkhead class A signaling pathway; ASSOCIATED WITH Diabetes Mellitus, Experimental ; Endotoxemia; Fetal Growth Retardation; FOUND IN cytoplasm; cytosol (ortholog); INTERACTS WITH (+)-alpha-tocopherol; (-)-epigallocatechin 3-gallate; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: GTP; MGC93820; PCK; Pepck; PEPCK-C; Phosphoenolpyruvate carboxykinase; phosphoenolpyruvate carboxykinase (GTP); phosphoenolpyruvate carboxykinase 1 (soluble); phosphoenolpyruvate carboxykinase 1, cytosolic; phosphoenolpyruvate carboxykinase, cytosolic; phosphoenolpyruvate carboxykinase, cytosolic (GTP); phosphoenolpyruvate carboxykinase, cytosolic [GTP]; phosphoenolpyruvate carboxylase; RATPEPCK
Homo sapiens (human) : PCK1 (phosphoenolpyruvate carboxykinase 1)  HGNC  Alliance
Mus musculus (house mouse) : Pck1 (phosphoenolpyruvate carboxykinase 1, cytosolic)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pck1 (phosphoenolpyruvate carboxykinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PCK1 (phosphoenolpyruvate carboxykinase 1)
Canis lupus familiaris (dog) : PCK1 (phosphoenolpyruvate carboxykinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pck1 (phosphoenolpyruvate carboxykinase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.03171,213,936 - 171,219,885 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03177,278,783 - 177,284,732 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43164,012,410 - 164,018,359 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13163,918,445 - 163,924,394 (+)NCBI
Celera3161,118,524 - 161,124,473 (+)NCBICelera
Cytogenetic Map3q42NCBI
RH 3.4 Map31498.6RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Pck1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3267
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-01-08
Status: ACTIVE