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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3267
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pck1
Name: phosphoenolpyruvate carboxykinase 1
Acc ID: CHEBI:81502
Term: 1,2,3,4,7,8-Hexachlorodibenzodioxin
Definition: A dibenzodioxine that has formula C12H2Cl6O2.
Chemical ID: MESH:C078219
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pck1decreases activityEXP 6480464CTD1,2,3,4,7,8-hexachlorodibenzodioxin results in decreased activity of PCK1 proteinPMID:15703265
Pck1decreases expressionEXP 6480464CTD1,2,3,4,7,8-hexachlorodibenzodioxin results in decreased expression of PCK1 mRNA; 1,2,3,4,7,8-hexachlorodibenzodioxin results in decreased expression of PCK1 proteinPMID:15703265
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