Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Pck1 (phosphoenolpyruvate carboxykinase 1, cytosolic) Mus musculus
Analyze
Symbol: Pck1
Name: phosphoenolpyruvate carboxykinase 1, cytosolic
Description: Exhibits phosphoenolpyruvate carboxykinase activity. Involved in several processes, including cellular response to potassium ion starvation; gluconeogenesis; and glycerol biosynthetic process from pyruvate. Localizes to the cytosol. Human ortholog(s) of this gene implicated in Alzheimer's disease and type 2 diabetes mellitus. Is expressed in several structures, including alimentary system; brown fat; liver; and urinary system. Orthologous to human PCK1 (phosphoenolpyruvate carboxykinase 1); PARTICIPATES IN forkhead class A signaling pathway; fructose-1,6-bisphosphatase deficiency pathway; gluconeogenesis pathway; INTERACTS WITH (-)-epigallocatechin 3-gallate; (9Z)-hexadecenoic acid; 1,1-dichloroethene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI265463; Pck-1; PEPCK; PEPCK-C; phosphoenolpyruvate carboxykinase, cytosolic; phosphoenolpyruvate carboxykinase, cytosolic [GTP]; phosphoenolpyruvate carboxylase
Orthologs:
Homo sapiens (human) : PCK1 (phosphoenolpyruvate carboxykinase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pck1 (phosphoenolpyruvate carboxykinase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pck1 (phosphoenolpyruvate carboxykinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PCK1 (phosphoenolpyruvate carboxykinase 1)
Canis lupus familiaris (dog) : PCK1 (phosphoenolpyruvate carboxykinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pck1 (phosphoenolpyruvate carboxykinase 1)
Sus scrofa (pig) : PCK1 (phosphoenolpyruvate carboxykinase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm382173,153,073 - 173,159,274 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372172,978,574 - 172,984,755 (+)NCBIGRCm37mm9NCBIm37
MGSCv362172,796,012 - 172,802,193 (+)NCBImm8
Celera2179,118,257 - 179,124,444 (+)NCBICelera
Cytogenetic Map2 H3NCBI
cM Map295.79NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Pck1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11062
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.