Gene: Tox2 (TOX high mobility group box family member 2) Rattus norvegicus
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Symbol: Tox2
Name: TOX high mobility group box family member 2
Description: ENCODES a protein that exhibits RNA polymerase II transcription factor binding; DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II proximal promoter sequence-specific DNA binding (ortholog); INVOLVED IN female gonad development; positive regulation of transcription by RNA polymerase II; response to gonadotropin; FOUND IN nucleus; nucleoplasm (ortholog); INTERACTS WITH bisphenol A; aflatoxin B1 (ortholog); aflatoxin B2 (ortholog)
AGR Description: Exhibits RNA polymerase II transcription factor binding activity; involved in female gonad development, positive regulation of transcription by RNA polymerase II, and response to gonadotropin; localizes to the nucleus; orthologous to human TOX2 (TOX high mobility group box family member 2).
Merged Description: Exhibits RNA polymerase II transcription factor binding activity; involved in female gonad development, positive regulation of transcription by RNA polymerase II, and response to gonadotropin; localizes to the nucleus; orthologous to human TOX2 (TOX high mobility group box family member 2); INTERACTS WITH bisphenol A; aflatoxin B1 (ortholog); aflatoxin B2 (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: GCX-1; Gcx1; granulosa cell HMG box protein 1; granulosa cell HMG-box protein 1; granulosa cell HMG-box protein-1
Orthologs:
Homo sapiens (human) : TOX2 (TOX high mobility group box family member 2)  HGNC  Alliance
Mus musculus (house mouse) : Tox2 (TOX high mobility group box family member 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tox2 (TOX high mobility group box family member 2)
Pan paniscus (bonobo/pygmy chimpanzee) : TOX2 (TOX high mobility group box family member 2)
Canis lupus familiaris (dog) : TOX2 (TOX high mobility group box family member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tox2 (TOX high mobility group box family member 2)
Sus scrofa (pig) : TOX2 (TOX high mobility group box family member 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03159,569,329 - 159,694,756 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03165,761,081 - 165,890,364 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43154,075,542 - 154,205,141 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13153,981,577 - 154,111,177 (+)NCBI
Celera3150,510,051 - 150,636,666 (+)NCBICelera
Cytogenetic Map3q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Tox2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735184
Created: 2004-02-05
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.