Gene: Arfgef2 (ADP ribosylation factor guanine nucleotide exchange factor 2) Rattus norvegicus
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Symbol: Arfgef2
Name: ADP ribosylation factor guanine nucleotide exchange factor 2
Description: ENCODES a protein that exhibits GABA receptor binding; myosin binding; ARF guanyl-nucleotide exchange factor activity (ortholog); INVOLVED IN exocytosis; endomembrane system organization (ortholog); endosome organization (ortholog); ASSOCIATED WITH Developmental Disabilities (ortholog); periventricular nodular heterotopia (ortholog); Periventricular Nodular Heterotopia 2 (ortholog); FOUND IN asymmetric synapse; axonemal microtubule; cytoplasm; INTERACTS WITH 2,6-dinitrotoluene; 6-propyl-2-thiouracil; bisphenol A
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited); Big2; brefeldin A-inhibited GEP 2; Brefeldin A-inhibited guanine nucleotide-exchange factor 2; brefeldin A-inhibited guanine nucleotide-exchange protein 2
Orthologs:
Homo sapiens (human) : ARFGEF2 (ADP ribosylation factor guanine nucleotide exchange factor 2)  HGNC  Alliance
Mus musculus (house mouse) : Arfgef2 (ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Arfgef2 (ADP ribosylation factor guanine nucleotide exchange factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ARFGEF2 (ADP ribosylation factor guanine nucleotide exchange factor 2)
Canis lupus familiaris (dog) : ARFGEF2 (ADP ribosylation factor guanine nucleotide exchange factor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Arfgef2 (ADP ribosylation factor guanine nucleotide exchange factor 2)
Sus scrofa (pig) : ARFGEF2 (ADP ribosylation factor guanine nucleotide exchange factor 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03163,570,435 - 163,656,612 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03169,732,829 - 169,817,296 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43157,967,942 - 158,051,359 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13157,873,977 - 157,957,394 (+)NCBI
Celera3154,129,988 - 154,212,427 (+)NCBICelera
Cytogenetic Map3q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model

Annotation    (Toggle Annotation Detail/Summary View)

Disease Annotations
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References - curated
References - uncurated
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Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
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Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
  
More on Arfgef2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 631430
Created: 2003-08-13
Species: Rattus norvegicus
Last Modified: 2019-01-30
Status: ACTIVE



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