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Gene: Arfgef2 (ARF guanine nucleotide exchange factor 2) Rattus norvegicus

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Symbol:

Arfgef2

Name:

ARF guanine nucleotide exchange factor 2 (Ensembl:ADP ribosylation factor guanine nucleotide exchange factor 2)

RGD ID:

631430

Description:

Enables GABA receptor binding activity and myosin binding activity. Involved in exocytosis. Located in several cellular components, including axonemal microtubule; symmetric synapse; and trans-Golgi network. Is active in several cellular components, including GABA-ergic synapse; glutamatergic synapse; and postsynapse. Human ortholog(s) of this gene implicated in periventricular nodular heterotopia. Orthologous to human ARFGEF2 (ARF guanine nucleotide exchange factor 2); INTERACTS WITH 17beta-estradiol; 2,6-dinitrotoluene; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

ADP ribosylation factor guanine nucleotide exchange factor 2; ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited); Big2; brefeldin A-inhibited GEP 2; Brefeldin A-inhibited guanine nucleotide-exchange factor 2; brefeldin A-inhibited guanine nucleotide-exchange protein 2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	175,966,575 - 176,052,715 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	175,966,579 - 176,052,713 (+)	Ensembl				GRCr8
mRatBN7.2	3	155,547,504 - 155,633,652 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	155,547,538 - 155,630,856 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	159,349,002 - 159,432,363 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	167,847,962 - 167,931,337 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	165,589,667 - 165,673,033 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	163,570,435 - 163,656,612 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	163,570,532 - 163,656,626 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	169,732,829 - 169,817,296 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	157,967,942 - 158,051,359 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	154,129,988 - 154,212,427 (+)	NCBI		Celera
RGSC_v3.1	3	157,873,977 - 157,957,394 (+)	NCBI
Cytogenetic Map	3	q42	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

developmental and epileptic encephalopathy 26 (ISO)

Developmental Disabilities (ISO)

genetic disease (ISO)

intellectual disability (ISO)

microcephaly (ISO)

Periventricular Laminar Heterotopia (ISO)

Periventricular Nodular Heterotopia 2 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17beta-estradiol (EXP,ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,4,6-tribromophenol (ISO)

2,6-dinitrotoluene (EXP)

2-hydroxypropanoic acid (ISO)

3,3',5,5'-tetrabromobisphenol A (ISO)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

aflatoxin B1 (EXP,ISO)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP,ISO)

Bisphenol B (ISO)

bisphenol F (ISO)

cadmium dichloride (EXP,ISO)

caffeine (ISO)

carbon nanotube (ISO)

chloroacetaldehyde (ISO)

chlorpromazine (EXP)

clobetasol (ISO)

clodronic acid (ISO)

copper(II) sulfate (ISO)

coumarin (ISO)

coumestrol (ISO)

cyclosporin A (EXP,ISO)

decabromodiphenyl ether (ISO)

Dibutyl phosphate (ISO)

dioxygen (ISO)

fenofibrate (EXP,ISO)

flutamide (EXP)

folic acid (ISO)

FR900359 (ISO)

gentamycin (EXP)

glycidol (EXP)

hydrazine (ISO)

ibuprofen (ISO)

ivermectin (ISO)

lead diacetate (ISO)

metformin (EXP)

methyl methanesulfonate (ISO)

paracetamol (ISO)

perfluorononanoic acid (ISO)

quercetin (ISO)

rac-lactic acid (ISO)

resveratrol (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

titanium dioxide (ISO)

triphenyl phosphate (ISO)

tungsten (ISO)

valproic acid (EXP)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

endomembrane system organization (IEA,ISO,ISS)

endosome organization (IEA,ISO,ISS)

exocytosis (IMP)

Golgi to plasma membrane transport (IEA,ISO,ISS)

intracellular signal transduction (IEA,ISO)

positive regulation of tumor necrosis factor production (IEA,ISO,ISS)

protein transport (IEA)

receptor recycling (IEA,ISO,ISS)

regulation of ARF protein signal transduction (IEA)

vesicle-mediated transport (IBA)

Cellular Component

asymmetric synapse (IDA)

axonemal microtubule (IDA)

cell projection (IEA)

centrosome (IEA)

cytoplasm (IEA)

cytoplasmic vesicle (IDA,IEA)

cytoskeleton (IEA)

cytosol (IEA,ISO)

dendrite (IEA)

dendritic spine (IDA)

endosome (IEA)

GABA-ergic synapse (IDA)

glutamatergic synapse (IDA)

Golgi apparatus (IEA)

Golgi membrane (IEA,ISO,ISS)

membrane (IEA,ISO)

microtubule organizing center (IEA,ISO,ISS)

perinuclear region of cytoplasm (IEA)

postsynapse (IDA)

presynapse (IDA)

recycling endosome (IEA,ISO,ISS)

symmetric synapse (IDA)

synapse (IEA)

trans-Golgi network (IDA,IEA)

Molecular Function

GABA receptor binding (IMP)

guanyl-nucleotide exchange factor activity (IBA,IEA,ISO,ISS,TAS)

myosin binding (IPI)

protein binding (IPI,ISO)

protein kinase A regulatory subunit binding (IEA,ISO,ISS)

References

References - curated

#	Reference Title	Reference Citation
1.	The brefeldin A-inhibited GDP/GTP exchange factor 2, a protein involved in vesicular trafficking, interacts with the beta subunits of the GABA receptors.	Charych EI, etal., J Neurochem 2004 Jul;90(1):173-89.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
4.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
5.	GOA pipeline	RGD automated data pipeline
6.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
8.	BIG1 is a binding partner of myosin IXb and regulates its Rho-GTPase activating protein activity.	Saeki N, etal., J Biol Chem. 2005 Mar 18;280(11):10128-34. Epub 2005 Jan 11.
9.	Mutations in ARFGEF2 implicate vesicle trafficking in neural progenitor proliferation and migration in the human cerebral cortex.	Sheen VL, etal., Nat Genet 2004 Jan;36(1):69-76. Epub 2003 Nov 30.
10.	Dominant-negative mutant of BIG2, an ARF-guanine nucleotide exchange factor, specifically affects membrane trafficking from the trans-Golgi network through inhibiting membrane association of AP-1 and GGA coat proteins.	Shinotsuka C, etal., Biochem Biophys Res Commun 2002 Jun 7;294(2):254-60.
11.	Localization of large ADP-ribosylation factor-guanine nucleotide exchange factors to different Golgi compartments: evidence for distinct functions in protein traffic.	Zhao X, etal., Mol Biol Cell. 2002 Jan;13(1):119-33.

Additional References at PubMed

PMID:10212200	PMID:10716990	PMID:12571360	PMID:15385626	PMID:15705715	PMID:16477018	PMID:17276987	PMID:19946888	PMID:20360857

Genomics

Comparative Map Data

Arfgef2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	175,966,575 - 176,052,715 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	3	175,966,579 - 176,052,713 (+)	Ensembl				GRCr8
mRatBN7.2	3	155,547,504 - 155,633,652 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	155,547,538 - 155,630,856 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	3	159,349,002 - 159,432,363 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	167,847,962 - 167,931,337 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	165,589,667 - 165,673,033 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	163,570,435 - 163,656,612 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	163,570,532 - 163,656,626 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	3	169,732,829 - 169,817,296 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	3	157,967,942 - 158,051,359 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	3	154,129,988 - 154,212,427 (+)	NCBI		Celera
RGSC_v3.1	3	157,873,977 - 157,957,394 (+)	NCBI
Cytogenetic Map	3	q42	NCBI

ARFGEF2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	20	48,921,711 - 49,036,693 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	20	48,921,711 - 49,036,693 (+)	Ensembl			hg38	GRCh38
GRCh37	20	47,538,248 - 47,653,230 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	20	46,971,682 - 47,086,637 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	20	46,971,833 - 47,083,645	NCBI
Celera	20	44,242,891 - 44,357,843 (+)	NCBI		Celera
Cytogenetic Map	20	q13.13	NCBI
HuRef	20	44,289,793 - 44,403,088 (+)	NCBI		HuRef
CHM1_1	20	47,442,300 - 47,557,463 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	20	50,690,875 - 50,806,194 (+)	NCBI		T2T-CHM13v2.0

Arfgef2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	166,647,371 - 166,739,972 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	166,647,508 - 166,739,972 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	2	166,805,451 - 166,898,052 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	166,805,588 - 166,898,052 (+)	Ensembl			mm10	GRCm38
MGSCv37	2	166,631,081 - 166,723,552 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	2	166,496,769 - 166,589,258 (+)	NCBI		MGSCv36	mm8
Celera	2	172,745,033 - 172,837,457 (+)	NCBI		Celera
Cytogenetic Map	2	H3	NCBI
cM Map	2	87.22	NCBI

Arfgef2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955445	9,070,234 - 9,153,213 (-)	Ensembl
ChiLan1.0	NW_004955445	9,069,803 - 9,153,746 (-)	NCBI	ChiLan1.0	ChiLan1.0

ARFGEF2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	21	54,664,735 - 54,779,786 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	20	54,657,833 - 54,771,872 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	20	45,262,330 - 45,376,237 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	20	46,330,174 - 46,442,518 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	20	46,327,753 - 46,442,518 (+)	Ensembl			panPan2	panpan1.1

ARFGEF2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	24	35,648,650 - 35,744,815 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	24	35,648,431 - 35,744,584 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	24	34,891,532 - 34,987,633 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	24	36,353,676 - 36,449,469 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	24	36,353,566 - 36,449,240 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	24	35,595,002 - 35,690,750 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	24	35,728,513 - 35,824,458 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	24	36,269,736 - 36,365,697 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Arfgef2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	189,719,109 - 189,809,174 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936514	5,172,584 - 5,262,836 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936514	5,172,752 - 5,262,823 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ARFGEF2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	17	50,631,092 - 50,732,243 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	17	50,631,844 - 50,732,253 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	17	56,982,797 - 57,082,784 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ARFGEF2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	14,947,347 - 15,058,217 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	2	14,947,351 - 15,030,772 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666050	63,449,416 - 63,561,858 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Arfgef2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624790	6,290,881 - 6,381,461 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624790	6,290,021 - 6,381,492 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Variants

Variants in Arfgef2
357 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	64
Count of miRNA genes:	57
Interacting mature miRNAs:	61
Transcripts:	ENSRNOT00000010054
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
12879876	Bw182	Body weight QTL 182		0.003	body mass (VT:0001259)	body weight (CMO:0000012)	3	145925360	166177555	Rat
2301411	Bp320	Blood pressure QTL 320		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	145925360	166177555	Rat
2312673	Scl63	Serum cholesterol level QTL 63		0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	3	98535255	168026850	Rat
1300113	Bp176	Blood pressure QTL 176	3.9		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	145956084	157309487	Rat
12879872	Cm97	Cardiac mass QTL 97		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	145925360	166177555	Rat
1598877	Bp285	Blood pressure QTL 285	1.5	0.03	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	120538241	165538241	Rat
1578653	Vnigr3	Vascular neointimal growth QTL 3	3.1		artery morphology trait (VT:0002191)	artery neointimal hyperplastic lesion area (CMO:0001414)	3	130656562	169034231	Rat
12879873	Cm96	Cardiac mass QTL 96		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	3	145925360	166177555	Rat
2302373	Gluco39	Glucose level QTL 39	5.01		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	3	98535386	161695835	Rat
12879874	Cm98	Cardiac mass QTL 98		0.005	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	3	145925360	166177555	Rat
1298068	Bp167	Blood pressure QTL 167		0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	141074471	169034231	Rat
12879875	Kidm64	Kidney mass QTL 64		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	145925360	166177555	Rat
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	31172320	163586636	Rat
2298477	Eau4	Experimental allergic uveoretinitis QTL 4		0.0011	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	3	137398739	169034231	Rat
8552791	Vie2	Viral induced encephalitis QTL 2	4.1		brain integrity trait (VT:0010579)	encephalitis incidence/prevalence measurement (CMO:0002361)	3	145956084	169034231	Rat
61335	Bp20	Blood pressure QTL 20	3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	141339236	155617360	Rat
1581568	Rf53	Renal function QTL 53			urine total protein amount (VT:0000032)	urine protein excretion rate to body weight ratio (CMO:0001099)	3	56395968	161299569	Rat
2317883	Alcrsp26	Alcohol response QTL 26	1.8	0.63	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	3	145526770	169034231	Rat
1578754	Stresp16	Stress response QTL 16	4	0.001	blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	3	112681431	157681431	Rat
1331726	Bp208	Blood pressure QTL 208	3.129		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	141339013	162184794	Rat
1598854	Memor10	Memory QTL 10	2		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	3	145956084	161299569	Rat
9589106	Insul23	Insulin level QTL 23	13.86	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	3	131635904	169034231	Rat
10755461	Coatc16	Coat color QTL 16			coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	3	122438700	167438700	Rat
8662816	Vetf4	Vascular elastic tissue fragility QTL 4	4		renal artery integrity trait (VT:0010642)	number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)	3	59242096	157323038	Rat
1559282	Emca5	Estrogen-induced mammary cancer QTL 5	3.9		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	3	43827364	169034231	Rat
2303620	Vencon4	Ventilatory control QTL 4	3.9		respiration trait (VT:0001943)	tidal volume (CMO:0000222)	3	127162703	168026850	Rat
631841	Niddm39	Non-insulin dependent diabetes mellitus QTL 39	3.36		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	94856903	159898684	Rat
1576306	Schws3	Schwannoma susceptibility QTL 3		0.001	nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	3	118839124	163839124	Rat
1300159	Kidm4	Kidney mass QTL 4	3.83		kidney mass (VT:0002707)	right kidney wet weight to body weight ratio (CMO:0001953)	3	121056165	157309487	Rat
2301971	Cm71	Cardiac mass QTL 71	4.63		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	3	41874578	155617519	Rat
2312659	Slep7	Serum leptin concentration QTL 7		0.001	blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	3	98535255	168026850	Rat
631673	Iddm13	Insulin dependent diabetes mellitus QTL 13	1.3	0.663	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	3	130193298	161695983	Rat
2301970	Bw81	Body weight QTL 81	5.19		body mass (VT:0001259)	body weight (CMO:0000012)	3	41874578	155617519	Rat
1578666	Vnigr1	Vascular neointimal growth QTL 1	4.6		artery morphology trait (VT:0002191)	artery lumen area (CMO:0001409)	3	149040888	168026850	Rat
1578656	Vnigr2	Vascular neointimal growth QTL 2	4.2		artery morphology trait (VT:0002191)	lesioned artery residual lumen area (CMO:0001417)	3	130656562	169034231	Rat
8552952	Pigfal13	Plasma insulin-like growth factor 1 level QTL 13			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	3	138799500	169034231	Rat
12879871	Am7	Aortic mass QTL 7		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	3	145925360	166177555	Rat
631541	Bp81	Blood pressure QTL 81	4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	124122556	169034231	Rat
2312670	Bw94	Body weight QTL 94		0.01	inguinal fat pad mass (VT:0010424)	inguinal fat pad weight to body weight ratio (CMO:0001253)	3	98535255	168026850	Rat

Markers in Region

D3Mgh2

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	3	176,036,425 - 176,036,586 (+)	Marker Load Pipeline
mRatBN7.2	3	155,617,360 - 155,617,519 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	163,640,325 - 163,640,485	NCBI	Rnor6.0
Rnor_5.0	3	169,801,009 - 169,801,169	UniSTS	Rnor5.0
RGSC_v3.4	3	158,037,866 - 158,038,027	RGD	RGSC3.4
RGSC_v3.4	3	158,037,867 - 158,038,027	UniSTS	RGSC3.4
Celera	3	154,198,939 - 154,199,099	UniSTS
RGSC_v3.1	3	157,943,902 - 157,944,063	RGD
RH 3.4 Map	3	1442.5	RGD
RH 3.4 Map	3	1442.5	UniSTS
SHRSP x BN Map	3	77.7599	UniSTS
SHRSP x BN Map	3	77.7599	RGD
Cytogenetic Map	3	q42	UniSTS

AU046990

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	155,553,925 - 155,554,202 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	163,577,270 - 163,577,551	NCBI	Rnor6.0
Rnor_5.0	3	169,739,656 - 169,739,937	UniSTS	Rnor5.0
RGSC_v3.4	3	157,974,169 - 157,974,445	UniSTS	RGSC3.4
Celera	3	154,136,226 - 154,136,502	UniSTS
Cytogenetic Map	3	q42	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	163	91	90	59	92	59	6	356	192	11	142	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001430231	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_181083	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006235640	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063283411	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC130053	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY255526	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000010054 ⟹ ENSRNOP00000010054

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	175,966,579 - 176,052,713 (+)	Ensembl
mRatBN7.2 Ensembl	3	155,547,538 - 155,630,856 (+)	Ensembl
Rnor_6.0 Ensembl	3	163,570,532 - 163,656,626 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000103177 ⟹ ENSRNOP00000096461

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	3	175,966,579 - 176,052,713 (+)	Ensembl
mRatBN7.2 Ensembl	3	155,547,538 - 155,630,856 (+)	Ensembl

RefSeq Acc Id:

NM_181083 ⟹ NP_851597

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	175,966,769 - 176,049,920 (+)	NCBI
mRatBN7.2	3	155,547,699 - 155,630,857 (+)	NCBI
Rnor_6.0	3	163,570,622 - 163,653,817 (+)	NCBI
Rnor_5.0	3	169,732,829 - 169,817,296 (+)	NCBI
RGSC_v3.4	3	157,967,942 - 158,051,359 (+)	RGD
Celera	3	154,129,988 - 154,212,427 (+)	RGD

Sequence:

show sequence

ATGCAGGAAAGCCAGACCAAGAGCATGTTCGTGTCCCGGGCCCTGGAGAAGATCCTAGCTGACA
AGGAGGTGAAGCGGCCCCAGCACTCCCAGCTGCGTAGGGCCTGCCAGGTGGCGCTCGATGAAAT
TAAAGCAGAACTAGAAAAGCAGAGGCTTGGCGCTGCGGCTCCACCAAAGGCAAACTTCATTGAA
GCTGACAAGTATTTCCTTCCATTCGAGCTGGCCTGCCAATCCAAGTCCCCTCGGGTGGTCAGCA
CGTCCCTGGACTGCTTGCAGAAACTCATCGCATATGGGCACATCACTGGCAATGCCCCCGACAG
TGGTGCTCCTGGGAAGCGGCTGATCGACAGGATTGTGGAGACGGTTTGCAATTGTTTTCAGGGC
CCTCAGACAGATGAAGGCGTTCAGCTACAGATAATTAAGGCTCTTCTGACTGCTGTGACTTCCC
CACACATTGAAATCCATGAGGGCACCATTCTACAGACAGTGAGGACATGCTACAATATCTATTT
GGCCAGCAAAAACCTCATCAATCAAACCACCGCCAAGGCCACGCTCACCCAAATGCTGAATGTC
ATCTTCACCCGCATGGAAAACCAAGTGTTACAGGAGGCCAGAGAATTGGAAAAACCAATCCAGT
CAAAACCTCAGTCCCCAGTGATCCAGGCCACAGCAGGATCTCCCAAGTTCAGTCGACTGAAGCA
GAGCCAGGCCCAGAGCAAACCAACAACTCCTGAAAAGACAGAATTGCCCAATGGTGACCACGCC
AGGAGTAGCCTAGGAAAAGTGAATTCAGAAAATGGAGAGGCTCACCGAGAAAGAGGCTCATCAA
TCTCCGGTAGAGCTGAGCCTTCTGGGGGATCTGACAATGGAGCCCAGGAGGTGGTGAAGGACAT
CTTAGAGGACGTGGTCACGTCTGCTGTGAAAGAAGCAGCAGAAAAGCAGGGGCTGCCGGAGCCT
GACCAAGCCCCAGGTGTGCCAGAGTGCCAGGAATGCACTGTTCCTCCTGCAGTTGATGAAAACT
CACAGACCAATGGCATAGCAGATGACAGGCAGTCGCTGTCCTCGGCAGATAACCTGGAACCAGA
TGCTCAAGGACACCCAGTGGCTGCTAGATTCTCTCACATTCTACAGAAGGATGCCTTCCTGGTG
TTTCGTTCCCTGTGTAAGCTGTCCATGAAGCCGCTTGGGGAAGGACCACCAGATCCAAAGTCCC
ACGAGCTTCGTTCCAAGGTGGTTTCCCTGCAGCTGCTGCTCTCTGTGCTGCAGAACGCTGGTCC
AGTCTTCAGGAGCCACGAGATGTTCGTCACTGCCATTAAGCAGTACCTGTGTGTAGCCCTTTCC
AAGAACGGCGTGTCCTCAGTGCCTGACGTCTTCGAACTCTCACTTGCGATTTTTCTTACTCTTC
TTTCAAACTTCAAGATGCACTTGAAAATGCAGATAGAGGTCTTTTTCAAAGAGATTTTCCTGAA
CATTTTAGAAACGTCCACAAGTTCTTTTGAGCACCGCTGGATGGTCATTCAGACCCTGACGAGA
ATTTGTGCAGATGCCCAGTGTGTTGTGGATATTTATGTCAACTACGACTGTGACTTAAATGCTG
CTAACATTTTTGAGCGTCTAGTAAATGATTTATCCAAAATCGCTCAGGGAAGAAGTGGACATGA
ACTGGGGATGACACCTCTACAGGAGCTCAGTCTGAGGAAGAAAGGCCTGGAGTGTCTGGTGTCC
ATTCTCAAGTGCATGGTGGAATGGAGCAAGGACCTGTATGTGAATCCCAACCACCAGGCCACCC
TGGGTCAGGAACGGCTTCCAGATCAGGAAATGGGGGACGGAAAAGGCCTTGACATGGCAAGACG
GTGCAGCGTGACATCAGTGGAGTCCACAGTGTCCTCGGGGACCCAGACAGCCATTCCAGATGAC
CCAGAGCAGTTTGAGGTCATCAAACAACAGAAGGAAATCATCGAGCATGGCATTGAGCTCTTCA
ATAAGAAGCCCAAGCGGGGAATCCAGTTTCTCCAAGAGCAAGGCATGCTAGGAGCAGCTGTAGA
AGATATTGCCCAATTTCTGCACCAGGAAGAGCGTCTGGATTCTACCCAGGTTGGTGAGTTTCTG
GGAGACAGCACAAGGTTTAACAAGGAGGTGATGTATGCCTATGTGGACCAACTGGACTTCTGTG
AAAAAGAGTTCGTCTCGGCCCTGAGGACATTCCTGGAGGGTTTCCGCCTGCCTGGGGAAGCCCA
GAAGATTGACCGGTTAATGGAGAAGTTTGCTGCACGATATATAGAGTGTAACCAAGGGCAAACC
CTGTTTGCTAGTGCTGACACGGCGTACGTCCTGGCCTACTCCATCATTATGCTAACTACAGACC
TGCATAGCCCTCAGGTAAAGAATAAAATGACAAAGGAACAGTATATTAAAATGAACCGGGGCAT
CAACGATAGTAAAGACCTACCTGAGGAGTACCTGTCCAGCATCTACGAAGAGATAGAAGGCAAG
AAGATTGCGATGAAGGAGACCAAGGAGCACACAATGGCAACGAAATCCACCAAGCAGAATGTAG
CCAGTGAGAAGCAGAGGCGGCTGCTGTACAATGTGGAGATGGAGCAGATGGCTAAGACAGCCAA
AGCTCTGATGGAGGCCGTGAGCCACGCCAAAGCCCCGTTTACCAGCGCCACACACTTGGACCAT
GTCCGGCCAATGTTCAAACTGGTGTGGACGCCACTGCTGGCAGCCTATAGCATCGGCCTACAGA
ACTGTGACGACACGGAGGTGGCCTCCCTGTGCTTGGAAGGCATCAGGTGTGCAGTCCGCATTGC
CTGCATCTTTGGAATGCAGCTGGAACGAGATGCCTATGTTCAGGCCCTTGCTCGCTTTTCCCTG
CTGACAGCCAGCTCCAGCATCACAGAAATGAAGCAGAAAAACATTGACACCATAAAGACACTCA
TCACTGTGGCTCACACCGATGGCAACTACCTTGGCAACTCCTGGCATGAGATCTTGAAGTGCAT
CAGCCAGCTGGAGCTCGCTCAGCTCATAGGAACTGGAGTGAAGACTCGCTACCTCTCTGGCTCT
GGGCGGGAAAGAGAAGGGAGCCTGAAGGGCCACAGTCTGGCAGGAGAAGAATTCATGGGTCTTG
GCCTCGGTAATTTGGTGAGTGGTGGTGTGGATAAAAGACAGATGGCCAGCTTCCAGGAGTCCGT
TGGTGAAACCAGCTCACAGAGTGTGGTTGTTGCAGTTGACAGAATTTTTACCGGCTCTACCAGA
CTGGATGGAAATGCAATAGTTGACTTTGTCCGCTGGCTGTGTGCTGTGTCCATGGATGAGCTGG
CTTCTCCCCACCATCCCCGCATGTTCAGCCTGCAGAAGATCGTGGAGATATCATACTACAACAT
GAACCGGATCCGGCTGCAGTGGTCTCGGATATGGCATGTCATTGGAGATCACTTCAATAAGGTC
GGCTGTAACCCCAATGAGGATGTGGCCATCTTTGCTGTTGACTCGCTGCGGCAACTCTCCATGA
AGTTTTTGGAGAAGGGAGAATTAGCCAACTTCCGATTTCAGAAGGATTTTCTGAGGCCGTTTGA
GCATATTATGAAGAAAAACAGGTCCCCAACCATCCGGGACATGGTCATCCGCTGCATTGCCCAG
ATGGTGAGCTCCCAGGCAGCCAACATCCGCTCAGGCTGGAAGAACATCTTTGCTGTGTTCCACC
AGGCCGCCTCTGACCACGATGGGAACATTGTGGAGCTGGCCTTCCAGACCACCGGCCACATTGT
CTCAACCATCTTCCAGCACCACTTCCCTGCGGCCATCGACTCCTTCCAGGACGCTGTGAAGTGC
TTGTCTGAGTTTGCCTGCAACGCAGCTTTCCCGGACACCAGTATGGAGGCCATCCGGCTCATCC
GCTTCTGTGGGAAATACGTCTCAGAGAGGCCACGGGTACTGCAGGAGTACACAAGCGATGACAT
GAATGTGGCTCCTGGTGACAGGGTGTGGGTCAGAGGCTGGTTCCCCATCCTCTTTGAGCTCTCC
TGCATCATTAACAGGTGCAAGTTAGATGTGCGCACAAGGGGACTGACAGTCATGTTCGAGATCA
TGAAGAGCTATGGCCACACCTTTGCAAAGCACTGGTGGCAGGACCTATTCAGAATTGTGTTTCG
GATTTTTGACAACATGAAACTCCCTGAGCAACAGTCGGAGAAATCAGAGTGGATGACGACCACC
TGCAATCACGCACTGTATGCTATTTGTGACGTATTCACCCAGTTCTACGAGGCTTTGCATGAAG
TGCTTCTCTCCGATGTGTTTGCACAGCTGCAGTGGTGCGTGAAGCAAGATAACGAGCAGTTGGC
CCGCTCGGGTACGAATTGCTTAGAGAACCTAGTGATATCCAATGGAGAGAAGTTCAGCCCTGCT
GTCTGGGATGAAACCTGCAATTGCATGTTGGATATTTTCAGAACCACCATCCCACATGTTTTGC
TGACGTGGAGACCTGCGGGGATGGAGGAGGAGGTGTCAGATAGACATCTGGACGTGGACCTGGA
CCGCCAGTCTTTAAGCAGCATAGACAGAAACGCCTCGGAGAGAGGACAGAGCCAGCTGTCTAAC
CCCACTGATGACAGCTGGAAGGGAGCACCGTATGCAAATCAGAAACTGCTGGCCAGCCTTCTCA
TCAAGTGTGTGGTTCAGCTGGAGCTGATACAGACCATTGACAACATCGTGTTCTACCCTGCGAC
CAGCAAAAAGGAGGATGCAGAGCACATGGTTGCTGCCCAGCAAGACACACTAGATGCAGATATC
CACATTGAGACGGAGAATCAGGGCATGTACAAGTTCATGTCTTCCCAGCACCTCTTCAAGCTGC
TAGACTGCCTGCAGGAGTCCCATTCCTTCTCCAAGGCCTTCAACTCCAACTATGAGCAGCGGAC
TGTCCTCTGGCGAGCTGGCTTCAAGGGCAAGTCCAAACCAAATCTCCTCAAACAAGAAACCAGC
AGCTTGGCCTGTTGCCTGAGGATCCTGTTTAGAATGTACGTTGATGAGAACCGCAGGGATTCCT
GGGGCGAAATACAGCAGCGGCTTTTAACCGTGTGCAGCGAAGCACTTGCCTATTTCATTACTGT
GAACTCTGAGAGCCATCGAGAAGCCTGGACGAGCCTCCTCCTCCTCCTTCTAACCAAAACCCTC
AAGATCAACGATGAAAAGTTCAAAGCCCACGCGTCAGTGTACTACCCCTACCTGTGTGAGATGA
TGCAGTTTGACCTGATCCCGGAGCTCCGAGCAGTTCTGCGAAAGTTCTTCCTGCGAATAGGCCT
GGTGTATAAGATATGGGTTCCAGAAGAGCCATCGCAAGTGCCAGCGGCATCGACAGCATGGTAG
CACCATGGCCACTGCTGTGGTTCTGTAGAATACCCGCCATGCCGTCCCAGCTGTGGAACGAGGA
GCTGCCCGCCATGTTGGGGTTTGGAACTGGAGAGCAGTGGCCTGAACACTGGCCTTGTCACAGT
CCCCAGCAGAGGCTCAAGGTGTCATGTATAACCATCACACACCAGTAACTGGGTGGGTGGGGAG
TCTGTTCCAACCGTCATTCCATTTCACTGACTGAACTGTCAGATCTGTGGTGAGGGCCACCATT
TCCTCCCGACCTCTGAGACTGGCCATAAATGATTTGTCGGAGGAAGTCACTCTCCTGGGAATCA
CTGAGCATTGCTGTATAGGTCCATGTTTATTAGAGAGTATTAATAAAATTCCTTGTAATCGCTA
ACAGCCAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006235640 ⟹ XP_006235702

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	175,966,575 - 176,052,715 (+)	NCBI
mRatBN7.2	3	155,547,504 - 155,633,652 (+)	NCBI
Rnor_6.0	3	163,570,435 - 163,656,612 (+)	NCBI
Rnor_5.0	3	169,732,829 - 169,817,296 (+)	NCBI

Sequence:

show sequence

CCACCAGTCACGTGGTCACGTGACGCGTTGCAACATGGCGGCGCTGTGGGGCCGGGGCGTCTCT
TCCTGACAGGGCGGCACGCACGGACGCGGCCGGTGCCGGCCGGGACGCCGAGTCCTCAGCCTCG
CTCTCCTGCTCGCTCTCACCGCCGGCTCGCGGGGTTGCCGGCCCCCGCAGGCCGGGGCCATGCA
GGAAAGCCAGACCAAGAGCATGTTCGTGTCCCGGGCCCTGGAGAAGATCCTAGCTGACAAGGAG
GTGAAGCGGCCCCAGCACTCCCAGCTGCGTAGGGCCTGCCAGGTGGCGCTCGATGAAATTAAAG
CAGAACTAGAAAAGCAGAGGCTTGGCGCTGCGGCTCCACCAAAGGCAAACTTCATTGAAGCTGA
CAAGTATTTCCTTCCATTCGAGCTGGCCTGCCAATCCAAGTCCCCTCGGGTGGTCAGCACGTCC
CTGGACTGCTTGCAGAAACTCATCGCATATGGGCACATCACTGGCAATGCCCCCGACAGTGGTG
CTCCTGGGAAGCGGCTGATCGACAGGATTGTGGAGACGGTTTGCAATTGTTTTCAGGGCCCTCA
GACAGATGAAGGCGTTCAGCTACAGATAATTAAGGCTCTTCTGACTGCTGTGACTTCCCCACAC
ATTGAAATCCACGAGGGCACCATTCTACAGACAGTGAGGACATGCTACAATATCTATTTGGCCA
GCAAAAACCTCATCAATCAAACCACCGCCAAGGCCACGCTCACCCAAATGCTGAATGTCATCTT
CACCCGCATGGAAAACCAAGTGTTACAGGAGGCCAGAGAATTGGAAAAACCAATCCAGTCAAAA
CCTCAGTCCCCAGTGATCCAGGCCACAGCAGGATCTCCCAAGTTCAGTCGACTGAAGCAGAGCC
AGGCCCAGAGCAAACCAACAACTCCTGAAAAGACAGAATTGCCCAATGGTGACCACGCCAGGAG
TAGCCTAGGAAAAGTGAATTCAGAAAATGGAGAGGCTCACCGAGAAAGAGGCTCATCAATCTCC
GGTAGAGCTGAGCCTTCTGGGGGATCTGACAATGGAGCCCAGGAGGTGGTGAAGGACATCTTAG
AGGACGTGGTCACGTCTGCTGTGAAAGCAGCAGAAAAGCAGGGGCTGCCGGAGCCTGACCAAGC
CCCAGGTGTGCCAGAGTGCCAGGAATGCACTGTTCCTCCTGCAGTTGATGAAAACTCACAGACC
AATGGCATAGCAGATGACAGGCAGTCGCTGTCCTCGGCAGATAACCTGGAACCAGATGCTCAAG
GACACCCAGTGGCTGCTAGATTCTCTCACATTCTACAGAAGGATGCCTTCCTGGTGTTTCGTTC
CCTGTGTAAGCTGTCCATGAAGCCGCTTGGGGAAGGACCACCAGATCCAAAGTCCCACGAGCTT
CGTTCCAAGGTGGTTTCCCTGCAGCTGCTGCTCTCTGTGCTGCAGAACGCTGGTCCAGTCTTCA
GGAGCCACGAGATGTTCGTCACTGCCATTAAGCAGTACCTGTGTGTAGCCCTTTCCAAGAACGG
CGTGTCCTCAGTGCCTGACGTCTTCGAACTCTCACTTGCGATTTTTCTTACTCTTCTTTCAAAC
TTCAAGATGCACTTGAAAATGCAGATAGAGGTCTTTTTCAAAGAGATTTTCCTGAACATTTTAG
AAACGTCCACAAGTTCTTTTGAGCACCGCTGGATGGTCATTCAGACCCTGACGAGAATTTGTGC
AGATGCCCAGTGTGTTGTGGATATTTATGTCAACTACGACTGTGACTTAAATGCTGCTAACATT
TTTGAGCGTCTAGTAAATGATTTATCCAAAATCGCTCAGGGAAGAAGTGGACATGAACTGGGGA
TGACACCTCTACAGGAGCTCAGTCTGAGGAAGAAAGGCCTGGAGTGTCTGGTGTCCATTCTCAA
GTGCATGGTGGAATGGAGCAAGGACCTGTATGTGAATCCCAACCACCAGGCCACCCTGGGTCAG
GAACGGCTTCCAGATCAGGAAATGGGGGACGGAAAAGGCCTTGACATGGCAAGACGGTGCAGCG
TGACATCAGTGGAGTCCACAGTGTCCTCGGGGACCCAGACAGCCATTCCAGATGACCCAGAGCA
GTTTGAGGTCATCAAACAACAGAAGGAAATCATCGAGCATGGCATTGAGCTCTTCAATAAGAAG
CCCAAGCGGGGAATCCAGTTTCTCCAAGAGCAAGGCATGCTAGGAGCAGCTGTAGAAGATATTG
CCCAATTTCTGCACCAGGAAGAGCGTCTGGATTCTACCCAGGTTGGTGAGTTTCTGGGAGACAG
CACAAGGTTTAACAAGGAGGTGATGTATGCCTATGTGGACCAACTGGACTTCTGTGAAAAAGAG
TTCGTCTCGGCCCTGAGGACATTCCTGGAGGGTTTCCGCCTGCCTGGGGAAGCCCAGAAGATTG
ACCGGTTAATGGAGAAGTTTGCTGCACGATATATAGAGTGTAACCAAGGGCAAACCCTGTTTGC
TAGTGCTGACACGGCGTACGTCCTGGCCTACTCCATCATTATGCTAACTACAGACCTGCATAGC
CCTCAGGTAAAGAATAAAATGACAAAGGAACAGTATATTAAAATGAACCGGGGCATCAACGATA
GTAAAGACCTACCTGAGGAGTACCTGTCCAGCATCTACGAAGAGATAGAAGGCAAGAAGATTGC
GATGAAGGAGACCAAGGAGCACACAATGGCAACGAAATCCACCAAGCAGAATGTAGCCAGTGAG
AAGCAGAGGCGGCTGCTGTACAATGTGGAGATGGAGCAGATGGCTAAGACAGCCAAAGCTCTGA
TGGAGGCCGTGAGCCACGCCAAAGCCCCGTTTACCAGCGCCACACACTTGGACCATGTCCGGCC
AATGTTCAAACTGGTGTGGACGCCACTGCTGGCAGCCTATAGCATCGGCCTACAGAACTGTGAC
GACACGGAGGTGGCCTCCCTGTGCTTGGAAGGCATCAGGTGTGCAGTCCGCATTGCCTGCATCT
TTGGAATGCAGCTGGAACGAGATGCCTATGTTCAGGCCCTTGCTCGCTTTTCCCTGCTGACAGC
CAGCTCCAGCATCACAGAAATGAAGCAGAAAAACATTGACACCATAAAGACACTCATCACTGTG
GCTCACACCGATGGCAACTACCTTGGCAACTCCTGGCATGAGATCTTGAAGTGCATCAGCCAGC
TGGAGCTCGCTCAGCTCATAGGAACTGGAGTGAAGACTCGCTACCTCTCTGGCTCTGGGCGGGA
AAGAGAAGGGAGCCTGAAGGGCCACAGTCTGGCAGGAGAAGAATTCATGGGTCTTGGCCTCGGT
AATTTGGTGAGTGGTGGTGTGGATAAAAGACAGATGGCCAGCTTCCAGGAGTCCGTTGGTGAAA
CCAGCTCACAGAGTGTGGTTGTTGCAGTTGACAGAATTTTTACCGGCTCTACCAGACTGGATGG
AAATGCAATAGTTGACTTTGTCCGCTGGCTGTGTGCTGTGTCCATGGATGAGCTGGCTTCTCCC
CACCATCCCCGCATGTTCAGCCTGCAGAAGATCGTGGAGATATCATACTACAACATGAACCGGA
TCCGGCTGCAGTGGTCTCGGATATGGCATGTCATTGGAGATCACTTCAATAAGGTCGGCTGTAA
CCCCAATGAGGATGTGGCCATCTTTGCTGTTGACTCGCTGCGGCAACTCTCCATGAAGTTTTTG
GAGAAGGGAGAATTAGCCAACTTCCGATTTCAGAAGGATTTTCTGAGGCCGTTTGAGCATATTA
TGAAGAAAAACAGGTCCCCAACCATCCGGGACATGGTCATCCGCTGCATTGCCCAGATGGTGAG
CTCCCAGGCAGCCAACATCCGCTCAGGCTGGAAGAACATCTTTGCTGTGTTCCACCAGGCCGCC
TCTGACCACGATGGGAACATTGTGGAGCTGGCCTTCCAGACCACCGGCCACATTGTCTCAACCA
TCTTCCAGCACCACTTCCCTGCGGCCATCGACTCCTTCCAGGACGCTGTGAAGTGCTTGTCTGA
GTTTGCCTGCAACGCAGCTTTCCCGGACACCAGTATGGAGGCCATCCGGCTCATCCGCTTCTGT
GGGAAATACGTCTCAGAGAGGCCACGGGTACTGCAGGAGTACACAAGCGATGACATGAATGTGG
CTCCTGGTGACAGGGTGTGGGTCAGAGGCTGGTTCCCCATCCTCTTTGAGCTCTCCTGCATCAT
TAACAGGTGCAAGTTAGATGTGCGCACAAGGGGACTGACAGTCATGTTCGAGATCATGAAGAGC
TATGGCCACACCTTTGCAAAGCACTGGTGGCAGGACCTATTCAGAATTGTGTTTCGGATTTTTG
ACAACATGAAACTCCCTGAGCAACAGTCGGAGAAATCAGAGTGGATGACGACCACCTGCAATCA
CGCACTGTATGCTATTTGTGACGTATTCACCCAGTTCTACGAGGCTTTGCATGAAGTGCTTCTC
TCCGATGTGTTTGCACAGCTGCAGTGGTGCGTGAAGCAAGATAACGAGCAGTTGGCCCGCTCGG
GTACGAATTGCTTAGAGAACCTAGTGATATCCAATGGAGAGAAGTTCAGCCCTGCTGTCTGGGA
TGAAACCTGCAATTGCATGTTGGATATTTTCAGAACCACCATCCCACATGTTTTGCTGACGTGG
AGACCTGCGGGGATGGAGGAGGAGGTGTCAGATAGACATCTGGACGTGGACCTGGACCGCCAGT
CTTTAAGCAGCATAGACAGAAACGCCTCGGAGAGAGGACAGAGCCAGCTGTCTAACCCCACTGA
TGACAGCTGGAAGGGAGCACCGTATGCAAATCAGAAACTGCTGGCCAGCCTTCTCATCAAGTGT
GTGGTTCAGCTGGAGCTGATACAGACCATTGACAACATCGTGTTCTACCCTGCGACCAGCAAAA
AGGAGGATGCAGAGCACATGGTTGCTGCCCAGCAAGACACACTAGATGCAGATATCCACATTGA
GACGGAGAATCAGGGCATGTACAAGTTCATGTCTTCCCAGCACCTCTTCAAGCTGCTAGACTGC
CTGCAGGAGTCCCATTCCTTCTCCAAGGCCTTCAACTCCAACTATGAGCAGCGGACTGTCCTCT
GGCGAGCTGGCTTCAAGGGCAAGTCCAAACCAAATCTCCTCAAACAAGAAACCAGCAGCTTGGC
CTGTTGCCTGAGGATCCTGTTTAGAATGTACGTTGATGAGAACCGCAGGGATTCCTGGGGCGAA
ATACAGCAGCGGCTTTTAACCGTGTGCAGCGAAGCACTTGCCTATTTCATTACTGTGAACTCTG
AGAGCCATCGAGAAGCCTGGACGAGCCTCCTCCTCCTCCTTCTAACCAAAACCCTCAAGATCAA
CGATGAAAAGTTCAAAGCCCACGCGTCAGTGTACTACCCCTACCTGTGTGAGATGATGCAGTTT
GACCTGATCCCGGAGCTCCGAGCAGTTCTGCGAAAGTTCTTCCTGCGAATAGGCCTGGTGTATA
AGATATGGGTTCCAGAAGAGCCATCGCAAGTGCCAGCGGCATCGACAGCATGGTAGCACCATGG
CCACTGCTGTGGTTCTGTAGAATACCCGCCATGCCGTCCCAGCTGTGGAACGAGGAGCTGCCCG
CCATGTTGGGGTTTGGAACTGGAGAGCAGTGGCCTGAACACTGGCCTTGTCACAGTCCCCAGCA
GAGGCTCAAGGTGTCATGTATAACCATCACACACCAGTAACTGGGTGGGTGGGGAGTCTGTTCC
AACCGTCATTCCATTTCACTGACTGAACTGTCAGATCTGTGGTGAGGGCCACCATTTCCTCCCG
ACCTCTGAGACTGGCCATAAATGATTTGTCGGAGGAAGTCACTCTCCTGGGAATCACTGAACAT
TGCTGTATAGGTCCATGTTTATTAGAGAGTATTAATAAAATTCCTTGTAATCGCTAACAGCCAC
CTAAGTGCGCTCGGTGTTTTGTTGTTTGAATGTGTTAGAGAAATTTGAATGTTTGTGTCAGTTT
TAGGTCAGCCTTGATAAAGTAGGGAAAGAGGGAGTGTTCCTTATGTCTTGTTTTGTTGTTGTTT
GAGTGATTTCTGAAACGTTTTACAAAGTTATATTATTAAAAATTTGATTAAAGGCAGAGTTTAG
TAGACTTAAGAGCTTGCAAGGTTTAAAGAAAACGTAGTGCCTCGTGGCTCCCTGGTTTAGTATC
TTGGGGAGACAAAGTCTGTAGGAAAAAATAATCTAAAAAAGGTGTTAGCCTTCCTGAAGTGTTT
GTGGGTGGATGTTCCGTTAAATTTTCCAGAATGCATTGTACATCTTTTCCTAAAATCTAGAGTA
TGAAATGTGATGAAAATGAAGTAATTGGCCCAGAGTTGGTTTATCTTTGAGTAAACGTTTTAGT
TTTTACCTCAGCAGAGTGCTAGTATGGCTGCTTTGCAGTCCCTGTTAAAGGGACCAGCAGAGGG
GGGGACCGTTCTTGTACCCCTCTCAGCCATGTATCGTGAGTGGAACTGGAGCTCCTGTGGGACT
AGCACAGATGTGCTGTGACAGTGGCAGAGGTGGCACCTAGAGCTTCTGTTAACTTGAGCCAGGA
GCTGGATTCTTTGACAAGATTAGATTCTGGGACCCTTTGGTTGGTAATGGTGCCATGTCCAGAA
CCACAGTAGAGCGACCTCTGAGTGCTCCCCACAACCACAGCAGCCAAGCTAGAAGCTTGGTCAG
TTCAGAGCCTATGAGAAAAAGAGCACACGCTCCCTCGCCTGCTCACTCTCTGCTCATCCAGAGC
ATCCACATCATGAGGCGCATTGGAAGCAGTCAGACTTCTGCCTACATTGAGTCCTACGAATTGG
GGTTGTATTGATGTCAACTCTGGTGCCTTAGAAGTTAGTCATCCTTGGGAATGTGTCTGTGAGA
CCGGACCCCTTCCTTTTTCTTTCTAGAGAGGGATTCTTGGTGCTTTTGCTATTTTCTCTCTTGT
TTTTGGCAGCCTTGCCACATGCTCAGTTTGGCCAGCAGAATTTGGATGTTTGCTTTTCTTTCCC
CAAAAGTATTTTCTCTACCAAAGCGGGGAACAAAGCAGGCTGAGGTCGTTACTGATGCACGTTG
AGGGGCAGGCCTGTGGAGATATGTGACTGAGTGGAGAGCGAGAGCACATTTGACTGACCCGTCC
TGGAATCCGGTGCATCTTCACAGCACACAAACCTGCACGAGACCTACTTCCTGGTGTGGCCACT
CAGCCAGCCCTCAGCTGTCGGTGGTTCCTGCAGCATTTGTACCACGCATGTAATCAGGGAACAT
GCATGTTCAGTGGGTACATCCCACCTAAGCTGTGTCCCTGACTGGTGGCTTTCCCTCCTGTCAC
GTGACATTCTGCTCATCTACACTAACCCATTGCCCCCATTGTCCCTCTGTAATTTTTGCCCCTT
ATAGGGTAGGGAGTGTGTCAGTGCATTTTTGTCTTGCTGAAAGCCTCAACTCGAATTTCTTTAT
AATTATATTTTGTTCTGTAAAAGACAAACTTTTCCGAGCAATGCATTTCAGTTGTCTAGCAATA
GATCTTTTAAAACAATGTCAAACCATTCAGGGTCATTTTTCTTGTCAGTGGCCAATGGCATCCC
TGACCTCCAGAAACAAGCCATGCAGTGTAAATTCCTTGTGGTGAACAAGTTTGTTCATGGCAAA
TGTGGTTTGACACCACACAGAGCAGGGGCAACTGTGTCTCCTCACAGGATGCTGCCCTGCTGTG
ACATAGAAGCAATGGTGTTGTGTCTTCCAAGGCCTTACTTCTTTTTCTGAGTGCATAAGTGTTG
GCTGTATGTTCTGGGTTCTCTAAAGACGTTTCTGTTCCCAAGCTGCTGTGCGGAGCAGTTTTGT
TCTTTTGTCTGTTAAGGAAATCACCAGCTTTGGCATCTGACCACCAAACGATGAGTGGGAGACA
TGGTTTCCGATGTGCATCTTCAAACACACCCTCCCTCATGTACAACCAAAGAACAGACAATATG
AAGTTGTATAGTAATATCTGCAAACACTTTCTGCCACCCCATGACTTTTGTACAAAATTCAGAG
AATCTGTAAAGAACCCCCCCTCAAAAATAGGCCTAAACTCTTTCGTTGTTCTTTTGTGATTCTG
GCTGTACATTTGGTGGTCTTTCTAGTTATTAAAAGAACGTGCTGACACATGTAGGTATGGCCGC
CCCACTCAGGTGTTTGTGGATGCTCATGGATGCTGGGTGCAGTAGGCACTGGATCCCTCTGAAC
TGTCTGGCTCGTGGTGAGGCAGATAGAGCGGGGCTCACCTGTACCTGGAGCTGTGCCACTGCAG
CTGTGTGGTTTGGGGAGCAGCCCCGAACGATTCCTCTGCAAACCCTCACTCTCAGAAAACCACA
CTCTTTGAATGTGTGGATCTTCTCAGTGTTCTGATTTTTAAAAAATTTTATCTTGCATATTTGC
ATCAAACATTTCTTTATGTGCAAAGTGTATGTTTTTGCTCTTTAAAACCGTCTCAGAGTTGGTT
ACCAGCTTCTTTGATTTCATCTATACACAATGATTAAGTGCATTTAATATCAGTAATTTAATGA
AAAGCATTCCTTGCCCAATGGATGTAAACATTTTTGAAAGAATAAAGCAGAATTATATAATATG
AAATGCTATGTAAAGTTTTCTATGTAAAAATATTATGTATAATACTGTTAAATACCCCATGCTT
TGATCAGGTGGAAAAAGAAATCAATAAAGTTTTAAAAGTGAA

hide sequence

RefSeq Acc Id:

XM_063283411 ⟹ XP_063139481

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	175,966,575 - 176,034,412 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001417160	(Get FASTA)	NCBI Sequence Viewer
	NP_851597	(Get FASTA)	NCBI Sequence Viewer
	XP_006235702	(Get FASTA)	NCBI Sequence Viewer
	XP_063139481	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAP04588	(Get FASTA)	NCBI Sequence Viewer
	EDL96429	(Get FASTA)	NCBI Sequence Viewer
	EDL96430	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000010054
	ENSRNOP00000010054.4
	ENSRNOP00000096461
GenBank Protein	Q7TSU1	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_851597 ⟸ NM_181083

- UniProtKB:

Q7TSU1 (UniProtKB/Swiss-Prot), A6JXH9 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MQESQTKSMFVSRALEKILADKEVKRPQHSQLRRACQVALDEIKAELEKQRLGAAAPPKANFIE
ADKYFLPFELACQSKSPRVVSTSLDCLQKLIAYGHITGNAPDSGAPGKRLIDRIVETVCNCFQG
PQTDEGVQLQIIKALLTAVTSPHIEIHEGTILQTVRTCYNIYLASKNLINQTTAKATLTQMLNV
IFTRMENQVLQEARELEKPIQSKPQSPVIQATAGSPKFSRLKQSQAQSKPTTPEKTELPNGDHA
RSSLGKVNSENGEAHRERGSSISGRAEPSGGSDNGAQEVVKDILEDVVTSAVKEAAEKQGLPEP
DQAPGVPECQECTVPPAVDENSQTNGIADDRQSLSSADNLEPDAQGHPVAARFSHILQKDAFLV
FRSLCKLSMKPLGEGPPDPKSHELRSKVVSLQLLLSVLQNAGPVFRSHEMFVTAIKQYLCVALS
KNGVSSVPDVFELSLAIFLTLLSNFKMHLKMQIEVFFKEIFLNILETSTSSFEHRWMVIQTLTR
ICADAQCVVDIYVNYDCDLNAANIFERLVNDLSKIAQGRSGHELGMTPLQELSLRKKGLECLVS
ILKCMVEWSKDLYVNPNHQATLGQERLPDQEMGDGKGLDMARRCSVTSVESTVSSGTQTAIPDD
PEQFEVIKQQKEIIEHGIELFNKKPKRGIQFLQEQGMLGAAVEDIAQFLHQEERLDSTQVGEFL
GDSTRFNKEVMYAYVDQLDFCEKEFVSALRTFLEGFRLPGEAQKIDRLMEKFAARYIECNQGQT
LFASADTAYVLAYSIIMLTTDLHSPQVKNKMTKEQYIKMNRGINDSKDLPEEYLSSIYEEIEGK
KIAMKETKEHTMATKSTKQNVASEKQRRLLYNVEMEQMAKTAKALMEAVSHAKAPFTSATHLDH
VRPMFKLVWTPLLAAYSIGLQNCDDTEVASLCLEGIRCAVRIACIFGMQLERDAYVQALARFSL
LTASSSITEMKQKNIDTIKTLITVAHTDGNYLGNSWHEILKCISQLELAQLIGTGVKTRYLSGS
GREREGSLKGHSLAGEEFMGLGLGNLVSGGVDKRQMASFQESVGETSSQSVVVAVDRIFTGSTR
LDGNAIVDFVRWLCAVSMDELASPHHPRMFSLQKIVEISYYNMNRIRLQWSRIWHVIGDHFNKV
GCNPNEDVAIFAVDSLRQLSMKFLEKGELANFRFQKDFLRPFEHIMKKNRSPTIRDMVIRCIAQ
MVSSQAANIRSGWKNIFAVFHQAASDHDGNIVELAFQTTGHIVSTIFQHHFPAAIDSFQDAVKC
LSEFACNAAFPDTSMEAIRLIRFCGKYVSERPRVLQEYTSDDMNVAPGDRVWVRGWFPILFELS
CIINRCKLDVRTRGLTVMFEIMKSYGHTFAKHWWQDLFRIVFRIFDNMKLPEQQSEKSEWMTTT
CNHALYAICDVFTQFYEALHEVLLSDVFAQLQWCVKQDNEQLARSGTNCLENLVISNGEKFSPA
VWDETCNCMLDIFRTTIPHVLLTWRPAGMEEEVSDRHLDVDLDRQSLSSIDRNASERGQSQLSN
PTDDSWKGAPYANQKLLASLLIKCVVQLELIQTIDNIVFYPATSKKEDAEHMVAAQQDTLDADI
HIETENQGMYKFMSSQHLFKLLDCLQESHSFSKAFNSNYEQRTVLWRAGFKGKSKPNLLKQETS
SLACCLRILFRMYVDENRRDSWGEIQQRLLTVCSEALAYFITVNSESHREAWTSLLLLLLTKTL
KINDEKFKAHASVYYPYLCEMMQFDLIPELRAVLRKFFLRIGLVYKIWVPEEPSQVPAASTAW

hide sequence

RefSeq Acc Id:

XP_006235702 ⟸ XM_006235640

- Peptide Label:

isoform X1

- Sequence:

show sequence

MQESQTKSMFVSRALEKILADKEVKRPQHSQLRRACQVALDEIKAELEKQRLGAAAPPKANFIE
ADKYFLPFELACQSKSPRVVSTSLDCLQKLIAYGHITGNAPDSGAPGKRLIDRIVETVCNCFQG
PQTDEGVQLQIIKALLTAVTSPHIEIHEGTILQTVRTCYNIYLASKNLINQTTAKATLTQMLNV
IFTRMENQVLQEARELEKPIQSKPQSPVIQATAGSPKFSRLKQSQAQSKPTTPEKTELPNGDHA
RSSLGKVNSENGEAHRERGSSISGRAEPSGGSDNGAQEVVKDILEDVVTSAVKAAEKQGLPEPD
QAPGVPECQECTVPPAVDENSQTNGIADDRQSLSSADNLEPDAQGHPVAARFSHILQKDAFLVF
RSLCKLSMKPLGEGPPDPKSHELRSKVVSLQLLLSVLQNAGPVFRSHEMFVTAIKQYLCVALSK
NGVSSVPDVFELSLAIFLTLLSNFKMHLKMQIEVFFKEIFLNILETSTSSFEHRWMVIQTLTRI
CADAQCVVDIYVNYDCDLNAANIFERLVNDLSKIAQGRSGHELGMTPLQELSLRKKGLECLVSI
LKCMVEWSKDLYVNPNHQATLGQERLPDQEMGDGKGLDMARRCSVTSVESTVSSGTQTAIPDDP
EQFEVIKQQKEIIEHGIELFNKKPKRGIQFLQEQGMLGAAVEDIAQFLHQEERLDSTQVGEFLG
DSTRFNKEVMYAYVDQLDFCEKEFVSALRTFLEGFRLPGEAQKIDRLMEKFAARYIECNQGQTL
FASADTAYVLAYSIIMLTTDLHSPQVKNKMTKEQYIKMNRGINDSKDLPEEYLSSIYEEIEGKK
IAMKETKEHTMATKSTKQNVASEKQRRLLYNVEMEQMAKTAKALMEAVSHAKAPFTSATHLDHV
RPMFKLVWTPLLAAYSIGLQNCDDTEVASLCLEGIRCAVRIACIFGMQLERDAYVQALARFSLL
TASSSITEMKQKNIDTIKTLITVAHTDGNYLGNSWHEILKCISQLELAQLIGTGVKTRYLSGSG
REREGSLKGHSLAGEEFMGLGLGNLVSGGVDKRQMASFQESVGETSSQSVVVAVDRIFTGSTRL
DGNAIVDFVRWLCAVSMDELASPHHPRMFSLQKIVEISYYNMNRIRLQWSRIWHVIGDHFNKVG
CNPNEDVAIFAVDSLRQLSMKFLEKGELANFRFQKDFLRPFEHIMKKNRSPTIRDMVIRCIAQM
VSSQAANIRSGWKNIFAVFHQAASDHDGNIVELAFQTTGHIVSTIFQHHFPAAIDSFQDAVKCL
SEFACNAAFPDTSMEAIRLIRFCGKYVSERPRVLQEYTSDDMNVAPGDRVWVRGWFPILFELSC
IINRCKLDVRTRGLTVMFEIMKSYGHTFAKHWWQDLFRIVFRIFDNMKLPEQQSEKSEWMTTTC
NHALYAICDVFTQFYEALHEVLLSDVFAQLQWCVKQDNEQLARSGTNCLENLVISNGEKFSPAV
WDETCNCMLDIFRTTIPHVLLTWRPAGMEEEVSDRHLDVDLDRQSLSSIDRNASERGQSQLSNP
TDDSWKGAPYANQKLLASLLIKCVVQLELIQTIDNIVFYPATSKKEDAEHMVAAQQDTLDADIH
IETENQGMYKFMSSQHLFKLLDCLQESHSFSKAFNSNYEQRTVLWRAGFKGKSKPNLLKQETSS
LACCLRILFRMYVDENRRDSWGEIQQRLLTVCSEALAYFITVNSESHREAWTSLLLLLLTKTLK
INDEKFKAHASVYYPYLCEMMQFDLIPELRAVLRKFFLRIGLVYKIWVPEEPSQVPAASTAW

hide sequence

Ensembl Acc Id:

ENSRNOP00000010054 ⟸ ENSRNOT00000010054

Ensembl Acc Id:

ENSRNOP00000096461 ⟸ ENSRNOT00000103177

RefSeq Acc Id:	XP_063139481 ⟸ XM_063283411
- Peptide Label:	isoform X2
- UniProtKB:	A6JXH9 (UniProtKB/TrEMBL)

Protein Domains

SEC7

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q7TSU1-F1-model_v2	AlphaFold	Q7TSU1	1-1791	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13692685

Promoter ID:

EPDNEW_R3210

Type:

multiple initiation site

Name:

Arfgef2_1

Description:

ADP ribosylation factor guanine nucleotide exchange factor 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	3	163,570,461 - 163,570,521	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:631430	AgrOrtholog
BioCyc Gene	G2FUF-46762	BioCyc
Ensembl Genes	ENSRNOG00000007485	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000010054	ENTREZGENE
	ENSRNOT00000010054.6	UniProtKB/Swiss-Prot
	ENSRNOT00000103177	ENTREZGENE
Gene3D-CATH	1.10.1000.11	UniProtKB/Swiss-Prot
	1.10.220.20	UniProtKB/Swiss-Prot
InterPro	ARM-type_fold	UniProtKB/Swiss-Prot
	DCB_dom	UniProtKB/Swiss-Prot
	Sec7/BIG1-like_C	UniProtKB/Swiss-Prot
	Sec7_C	UniProtKB/Swiss-Prot
	Sec7_C_sf	UniProtKB/Swiss-Prot
	Sec7_dom	UniProtKB/Swiss-Prot
	Sec7_dom_sf	UniProtKB/Swiss-Prot
	Sec7_N	UniProtKB/Swiss-Prot
KEGG Report	rno:296380	UniProtKB/Swiss-Prot
NCBI Gene	296380	ENTREZGENE
PANTHER	BREFELDIN A-INHIBITED GUANINE NUCLEOTIDE-EXCHANGE PROTEIN 2	UniProtKB/Swiss-Prot
	GUANYL-NUCLEOTIDE EXCHANGE FACTOR	UniProtKB/Swiss-Prot
Pfam	BIG2_C	UniProtKB/Swiss-Prot
	DCB	UniProtKB/Swiss-Prot
	DUF1981	UniProtKB/Swiss-Prot
	Sec7	UniProtKB/Swiss-Prot
	Sec7_N	UniProtKB/Swiss-Prot
PhenoGen	Arfgef2	PhenoGen
PROSITE	SEC7	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000007485	RatGTEx
SMART	Sec7	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF48371	UniProtKB/Swiss-Prot
	SSF48425	UniProtKB/Swiss-Prot
UniProt	A0A8I6AV44_RAT	UniProtKB/TrEMBL
	A6JXH9	ENTREZGENE, UniProtKB/TrEMBL
	A6JXI0_RAT	UniProtKB/TrEMBL
	BIG2_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2024-11-07	Arfgef2	ARF guanine nucleotide exchange factor 2	Arfgef2	ADP ribosylation factor guanine nucleotide exchange factor 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2015-11-25	Arfgef2	ADP ribosylation factor guanine nucleotide exchange factor 2	Arfgef2	ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-09-10	Arfgef2	ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)			Symbol and Name status set to approved	1299863	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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