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Gene: Ghrh (growth hormone releasing hormone) Rattus norvegicus
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Symbol: Ghrh
Name: growth hormone releasing hormone
Description: Exhibits growth hormone-releasing hormone activity. Involved in several processes, including circadian sleep/wake cycle, non-REM sleep; growth hormone secretion; and positive regulation of cell communication. Localizes to the axon terminus; extracellular space; and perikaryon. Used to study myocardial infarction and prostatic hypertrophy. Biomarker of sleep disorder. Human ortholog(s) of this gene implicated in autoimmune polyendocrine syndrome type 1; endometrial cancer; ovarian cancer; and renal cell carcinoma. Orthologous to human GHRH (growth hormone releasing hormone); INTERACTS WITH 17alpha-ethynylestradiol; 3,3',5-triiodo-L-thyronine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: GHRF; GRF; growth hormone-releasing factor; growth hormone-releasing hormone; somatoliberin
Orthologs:
Homo sapiens (human) : GHRH (growth hormone releasing hormone)  HGNC  Alliance
Mus musculus (house mouse) : Ghrh (growth hormone releasing hormone)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ghrh (growth hormone releasing hormone)
Pan paniscus (bonobo/pygmy chimpanzee) : GHRH (growth hormone releasing hormone)
Canis lupus familiaris (dog) : GHRH (growth hormone releasing hormone)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ghrh (growth hormone releasing hormone)
Sus scrofa (pig) : GHRH (growth hormone releasing hormone)
Chlorocebus sabaeus (African green monkey) : GHRH (growth hormone releasing hormone)
Heterocephalus glaber (naked mole-rat) : Ghrh (growth hormone releasing hormone)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.03153,449,124 - 153,468,794 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3153,449,125 - 153,468,794 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03158,251,824 - 158,270,812 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43148,027,235 - 148,046,352 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13147,933,144 - 147,952,261 (-)NCBI
Celera3144,698,178 - 144,717,216 (-)NCBICelera
Cytogenetic Map3q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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Annotation    (Toggle Annotation Detail/Summary View)

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Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
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Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
  
More on Ghrh
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 61883
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.