Nnat (neuronatin) - Rat Genome Database

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Gene: Nnat (neuronatin) Rattus norvegicus
Analyze
Symbol: Nnat
Name: neuronatin
RGD ID: 620155
Description: Involved in neuron differentiation. Located in cytoplasm. Orthologous to human NNAT (neuronatin); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: MGC156562; neuronatin alpha; Peg5
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83166,646,373 - 166,648,845 (+)NCBIGRCr8
mRatBN7.23146,225,941 - 146,228,868 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3146,226,407 - 146,228,834 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3150,051,744 - 150,054,205 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03158,552,933 - 158,555,392 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03156,294,850 - 156,297,310 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03154,043,873 - 154,046,334 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3154,043,873 - 154,046,330 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03161,553,358 - 161,557,429 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43148,269,404 - 148,271,781 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13148,175,312 - 148,177,690 (+)NCBI
Celera3144,930,375 - 144,932,836 (+)NCBICelera
Cytogenetic Map3q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
NnatRatAicardi-Goutieres Syndrome 5  ISORGD:7308418554872ClinVar Annotator: match by term: Aicardi-Goutieres syndrome 5ClinVarPMID:28492532
NnatRatcongenital disorder of glycosylation  ISORGD:7308418554872ClinVar Annotator: match by term: Congenital disorder of glycosylationClinVarPMID:28492532
NnatRatfocal epilepsy  ISORGD:7308418554872ClinVar Annotator: match by term: Focal-onset seizureClinVarPMID:32581362
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
NnatRatlung non-small cell carcinoma  ISORGD:73084111554173CTD Direct Evidence: marker/mechanismCTDPMID:17043644
NnatRatneuroblastoma  ISORGD:73084111554173CTD Direct Evidence: marker/mechanismCTDPMID:17762496

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Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
NnatRat17alpha-ethynylestradiol increases expressionISORGD:7308426480464Ethinyl Estradiol results in increased expression of NNAT mRNACTDPMID:17942748
NnatRat17alpha-ethynylestradiol decreases expressionEXP 6480464Ethinyl Estradiol results in decreased expression of NNAT mRNACTDPMID:15834898
NnatRat17alpha-ethynylestradiol multiple interactionsISORGD:7308426480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of NNAT mRNACTDPMID:17942748
NnatRat17alpha-ethynylestradiol affects expressionISORGD:7308426480464Ethinyl Estradiol affects the expression of NNAT mRNACTDPMID:17555576
NnatRat17beta-estradiol increases expressionISORGD:7308426480464Estradiol results in increased expression of NNAT mRNACTDPMID:19484750
NnatRat17beta-estradiol decreases expressionEXP 6480464Estradiol results in decreased expression of NNAT mRNACTDPMID:32145629
NnatRat2,3,7,8-tetrachlorodibenzodioxine increases expressionISORGD:7308416480464Tetrachlorodibenzodioxin results in increased expression of NNAT mRNACTDPMID:19684285
NnatRat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of NNAT mRNACTDPMID:33387578
NnatRat2,3,7,8-tetrachlorodibenzodioxine increases expressionEXP 6480464Tetrachlorodibenzodioxin results in increased expression of NNAT mRNACTDPMID:26232522
NnatRat2,3,7,8-tetrachlorodibenzodioxine affects expressionISORGD:7308426480464Tetrachlorodibenzodioxin affects the expression of NNAT mRNACTDPMID:21570461|PMID:24680724
NnatRat2,3,7,8-tetrachlorodibenzodioxine increases expressionISORGD:7308426480464Tetrachlorodibenzodioxin results in increased expression of NNAT mRNACTDPMID:17942748|PMID:19684285
NnatRat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISORGD:7308426480464[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of NNAT mRNACTDPMID:17942748
NnatRat2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expressionISORGD:73084264804642,2',4,4',5-brominated diphenyl ether affects the expression of NNAT mRNACTDPMID:38648751
NnatRat3,3',5-triiodo-L-thyronine decreases expressionEXP 6480464Triiodothyronine results in decreased expression of NNAT mRNACTDPMID:29357290
NnatRat3,4-methylenedioxymethamphetamine decreases expressionISORGD:7308426480464N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of NNAT mRNACTDPMID:26251327
NnatRat3,4-methylenedioxymethamphetamine increases methylationISORGD:7308426480464N-Methyl-3,4-methylenedioxyamphetamine results in increased methylation of NNAT promoterCTDPMID:26251327
NnatRat4,4'-sulfonyldiphenol increases expressionISORGD:7308426480464bisphenol S results in increased expression of NNAT mRNACTDPMID:30951980
NnatRat4,4'-sulfonyldiphenol affects methylationISORGD:7308426480464bisphenol S affects the methylation of NNAT exonCTDPMID:33297965
NnatRat5-aza-2'-deoxycytidine multiple interactionsEXP 6480464[Decitabine affects the methylation of NNAT protein] which affects the expression of NNAT mRNACTDPMID:18381416
NnatRat5-aza-2'-deoxycytidine increases expressionISORGD:7308416480464Decitabine results in increased expression of NNAT mRNACTDPMID:17762496

1 to 20 of 106 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
NnatRatbrain development involved_inIEAInterPro:IPR0248851600115GO_REF:0000002InterProGO_REF:0000002
NnatRatestablishment of localization in cell acts_upstream_ofISORGD:7308421624291 PMID:15793245RGDPMID:15793245
NnatRatinsulin secretion acts_upstream_ofISORGD:7308421624291 PMID:15793245RGDPMID:15793245
NnatRatneuron differentiation  IEP 1358323 RGD 
NnatRatpositive regulation of insulin secretion involved_inIBAMGI:104716|PANTHER:PTN0003925811600115GO_REF:0000033GO_CentralGO_REF:0000033
NnatRatpositive regulation of insulin secretion acts_upstream_of_or_withinISORGD:7308421624291 PMID:15793245RGDPMID:15793245
NnatRatregulation of protein localization acts_upstream_of_or_withinISORGD:7308421624291 PMID:15793245RGDPMID:15793245
NnatRatresponse to glucose acts_upstream_of_or_withinISORGD:7308421624291 PMID:15793245RGDPMID:15793245

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
NnatRatcytoplasm is_active_inIBAMGI:104716|PANTHER:PTN0003925811600115GO_REF:0000033GO_CentralGO_REF:0000033
NnatRatcytoplasm  IDA 597538584MMO:0000662RGD 
NnatRatcytoplasm located_inISORGD:7308421624291 PMID:15793245RGDPMID:15793245
NnatRatmembrane located_inIEAUniProtKB-KW:KW-04721600115GO_REF:0000043UniProtGO_REF:0000043


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#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Molecular cloning of a novel mRNA (neuronatin) that is highly expressed in neonatal mammalian brain. Joseph R, etal., Biochem Biophys Res Commun 1994 Jun 30;201(3):1227-34.
4. Neuronatin mRNA: alternatively spliced forms of a novel brain-specific mammalian developmental gene. Joseph R, etal., Brain Res 1995 Aug 28;690(1):92-8.
5. Neuronatin mRNA in PC12 cells: downregulation by nerve growth factor. Joseph R, etal., Brain Res 1996 Oct 28;738(1):32-8.
6. Dynamic Changes in the Localization of Neuronatin-Positive Cells during Neurogenesis in the Embryonic Rat Brain. Kanno N, etal., Cells Tissues Organs. 2019;207(3-4):127-137. doi: 10.1159/000504359. Epub 2019 Dec 5.
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Identification of cell-specific messenger ribonucleic acids in oxytocinergic and vasopressinergic magnocellular neurons in rat supraoptic nucleus by single-cell differential hybridization. Yamashita M, etal., Endocrinology 2002 Nov;143(11):4464-76.
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PMID:12477932   PMID:15793245   PMID:19851307   PMID:20509861   PMID:21935485   PMID:24370184   PMID:30869556  



Nnat
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83166,646,373 - 166,648,845 (+)NCBIGRCr8
mRatBN7.23146,225,941 - 146,228,868 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3146,226,407 - 146,228,834 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3150,051,744 - 150,054,205 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03158,552,933 - 158,555,392 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03156,294,850 - 156,297,310 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03154,043,873 - 154,046,334 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3154,043,873 - 154,046,330 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03161,553,358 - 161,557,429 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43148,269,404 - 148,271,781 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13148,175,312 - 148,177,690 (+)NCBI
Celera3144,930,375 - 144,932,836 (+)NCBICelera
Cytogenetic Map3q42NCBI
NNAT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382037,521,250 - 37,523,690 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2037,521,206 - 37,523,690 (+)EnsemblGRCh38hg38GRCh38
GRCh372036,149,652 - 36,152,092 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362035,583,021 - 35,585,506 (+)NCBINCBI36Build 36hg18NCBI36
Build 342035,583,020 - 35,585,502NCBI
Celera2032,856,869 - 32,859,355 (+)NCBICelera
Cytogenetic Map20q11.23NCBI
HuRef2032,885,325 - 32,887,812 (+)NCBIHuRef
CHM1_12036,052,423 - 36,054,893 (+)NCBICHM1_1
T2T-CHM13v2.02039,245,345 - 39,247,787 (+)NCBIT2T-CHM13v2.0
Nnat
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392157,401,936 - 157,404,445 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2157,401,998 - 157,404,442 (+)EnsemblGRCm39 Ensembl
GRCm382157,560,078 - 157,562,525 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2157,560,078 - 157,562,522 (+)EnsemblGRCm38mm10GRCm38
MGSCv372157,385,846 - 157,388,258 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362157,251,564 - 157,253,945 (+)NCBIMGSCv36mm8
Celera2163,504,157 - 163,506,569 (+)NCBICelera
Cytogenetic Map2H1NCBI
cM Map278.4NCBI
Nnat
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544519,121,164 - 19,125,514 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544519,121,164 - 19,125,514 (-)NCBIChiLan1.0ChiLan1.0
NNAT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22143,246,341 - 43,251,217 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12043,239,925 - 43,244,315 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02033,842,071 - 33,845,575 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12034,955,233 - 34,959,493 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2034,955,234 - 34,959,493 (+)Ensemblpanpan1.1panPan2
NNAT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12426,119,153 - 26,121,573 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2426,118,991 - 26,120,906 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2425,764,843 - 25,767,256 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02426,815,822 - 26,818,235 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2426,815,835 - 26,817,449 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12426,091,104 - 26,093,520 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02426,198,494 - 26,200,910 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02426,686,053 - 26,688,469 (+)NCBIUU_Cfam_GSD_1.0
Nnat
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640175,007,353 - 175,009,820 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365613,739,664 - 3,742,154 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365613,739,664 - 3,744,015 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NNAT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11740,625,990 - 40,629,523 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21746,042,960 - 46,045,928 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NNAT
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1226,229,765 - 26,232,249 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl226,230,696 - 26,232,127 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605075,102,293 - 75,105,653 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nnat
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248422,122,968 - 2,125,490 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Nnat
9 total Variants

Predicted Target Of
Summary Value
Count of predictions:787
Count of miRNA genes:252
Interacting mature miRNAs:321
Transcripts:ENSRNOT00000034166, ENSRNOT00000068863, ENSRNOT00000072502
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 43 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
12879876Bw182Body weight QTL 1820.003body mass (VT:0001259)body weight (CMO:0000012)3145925360166177555Rat
2301411Bp320Blood pressure QTL 3200.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3145925360166177555Rat
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
1300113Bp176Blood pressure QTL 1763.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3145956084157309487Rat
12879872Cm97Cardiac mass QTL 970.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3145925360166177555Rat
1598877Bp285Blood pressure QTL 2851.50.03arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3120538241165538241Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3130656562169034231Rat
12879873Cm96Cardiac mass QTL 960.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)3145925360166177555Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
12879874Cm98Cardiac mass QTL 980.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)3145925360166177555Rat

1 to 10 of 43 rows
BI286603  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23146,228,606 - 146,228,775 (+)MAPPERmRatBN7.2
Rnor_6.03154,046,073 - 154,046,241NCBIRnor6.0
Rnor_5.03161,553,451 - 161,553,619UniSTSRnor5.0
RGSC_v3.43148,271,523 - 148,271,691UniSTSRGSC3.4
Celera3144,932,575 - 144,932,743UniSTS
RH 3.4 Map31352.6UniSTS
Cytogenetic Map3q42UniSTS
AA858569  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23146,228,607 - 146,228,827 (+)MAPPERmRatBN7.2
Rnor_6.03154,046,074 - 154,046,293NCBIRnor6.0
Rnor_5.03161,553,399 - 161,553,618UniSTSRnor5.0
RGSC_v3.43148,271,524 - 148,271,743UniSTSRGSC3.4
Celera3144,932,576 - 144,932,795UniSTS
RH 3.4 Map31353.3UniSTS
Cytogenetic Map3q42UniSTS
BF413147  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr83166,648,127 - 166,648,279 (+)Marker Load Pipeline
mRatBN7.23146,228,150 - 146,228,302 (+)MAPPERmRatBN7.2
Rnor_6.03154,045,617 - 154,045,768NCBIRnor6.0
Rnor_5.03161,553,924 - 161,554,075UniSTSRnor5.0
RGSC_v3.43148,271,067 - 148,271,218UniSTSRGSC3.4
Celera3144,932,119 - 144,932,270UniSTS
RH 3.4 Map31354.1UniSTS
Cytogenetic Map3q42UniSTS
BI281696  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23146,228,368 - 146,228,531 (+)MAPPERmRatBN7.2
Rnor_6.03154,045,835 - 154,045,997NCBIRnor6.0
Rnor_5.03161,553,695 - 161,553,857UniSTSRnor5.0
RGSC_v3.43148,271,285 - 148,271,447UniSTSRGSC3.4
Celera3144,932,337 - 144,932,499UniSTS
RH 3.4 Map31352.3UniSTS
Cytogenetic Map3q42UniSTS
Nnat  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23146,228,077 - 146,228,693 (+)MAPPERmRatBN7.2
Rnor_6.03154,045,544 - 154,046,159NCBIRnor6.0
Rnor_5.03161,553,533 - 161,554,148UniSTSRnor5.0
RGSC_v3.43148,270,994 - 148,271,609UniSTSRGSC3.4
Celera3144,932,046 - 144,932,661UniSTS
Cytogenetic Map3q42UniSTS
Nnat  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23146,228,502 - 146,228,697 (+)MAPPERmRatBN7.2
Rnor_6.03154,045,969 - 154,046,163NCBIRnor6.0
Rnor_5.03161,553,529 - 161,553,723UniSTSRnor5.0
RGSC_v3.43148,271,419 - 148,271,613UniSTSRGSC3.4
Celera3144,932,471 - 144,932,665UniSTS
Cytogenetic Map3q42UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31


1 to 22 of 22 rows
RefSeq Transcripts NM_001270867 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001429813 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001429814 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001429815 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_053601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_181687 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_073089 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008762390 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063284795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC127473 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB711943 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DY315493 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FM037467 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212548 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213121 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213143 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U08290 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U09785 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
1 to 22 of 22 rows

Ensembl Acc Id: ENSRNOT00000034166   ⟹   ENSRNOP00000034212
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3146,226,416 - 146,228,834 (+)Ensembl
Rnor_6.0 Ensembl3154,043,873 - 154,046,330 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000072502   ⟹   ENSRNOP00000064325
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3146,226,407 - 146,228,834 (+)Ensembl
Rnor_6.0 Ensembl3154,043,873 - 154,046,330 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000098078   ⟹   ENSRNOP00000096996
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3146,226,416 - 146,228,108 (+)Ensembl
RefSeq Acc Id: NM_001270867   ⟹   NP_001257796
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83166,646,384 - 166,648,845 (+)NCBI
mRatBN7.23146,226,407 - 146,228,868 (+)NCBI
Rnor_6.03154,043,873 - 154,046,334 (+)NCBI
Rnor_5.03161,553,358 - 161,557,429 (-)NCBI
Celera3144,930,375 - 144,932,836 (+)NCBI
Sequence:
RefSeq Acc Id: NM_053601   ⟹   NP_446053
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83166,646,384 - 166,648,845 (+)NCBI
mRatBN7.23146,226,407 - 146,228,868 (+)NCBI
Rnor_6.03154,043,873 - 154,046,334 (+)NCBI
Rnor_5.03161,553,358 - 161,557,429 (-)NCBI
RGSC_v3.43148,269,404 - 148,271,781 (+)RGD
Celera3144,930,375 - 144,932,836 (+)NCBI
Sequence:
RefSeq Acc Id: NM_181687   ⟹   NP_859015
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83166,646,384 - 166,648,845 (+)NCBI
mRatBN7.23146,226,407 - 146,228,868 (+)NCBI
Rnor_6.03154,043,873 - 154,046,334 (+)NCBI
Rnor_5.03161,553,358 - 161,557,429 (-)NCBI
RGSC_v3.43148,269,404 - 148,271,781 (+)RGD
Celera3144,930,375 - 144,932,836 (+)NCBI
Sequence:
RefSeq Acc Id: NR_073089
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83166,646,384 - 166,648,845 (+)NCBI
mRatBN7.23146,226,407 - 146,228,868 (+)NCBI
Rnor_6.03154,043,873 - 154,046,334 (+)NCBI
Rnor_5.03161,553,358 - 161,557,429 (-)NCBI
Celera3144,930,375 - 144,932,836 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008762390   ⟹   XP_008760612
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83166,646,383 - 166,648,845 (+)NCBI
mRatBN7.23146,225,941 - 146,228,868 (+)NCBI
Rnor_6.03154,043,878 - 154,045,574 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063284795   ⟹   XP_063140865
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83166,646,373 - 166,648,845 (+)NCBI
RefSeq Acc Id: NP_446053   ⟸   NM_053601
- Peptide Label: isoform alpha
- UniProtKB: A0JPK6 (UniProtKB/Swiss-Prot),   Q62663 (UniProtKB/Swiss-Prot),   Q62649 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_859015   ⟸   NM_181687
- Peptide Label: isoform beta
- UniProtKB: Q62649 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001257796   ⟸   NM_001270867
- Peptide Label: isoform 3
- UniProtKB: Q62649 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_008760612   ⟸   XM_008762390
- Peptide Label: isoform X2
- Sequence:
Ensembl Acc Id: ENSRNOP00000064325   ⟸   ENSRNOT00000072502

Name Modeler Protein Id AA Range Protein Structure
AF-Q62649-F1-model_v2 AlphaFold Q62649 1-81 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13692613
Promoter ID:EPDNEW_R3138
Type:single initiation site
Name:Nnat_1
Description:neuronatin
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03154,043,915 - 154,043,975EPDNEW


1 to 25 of 25 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-47050 BioCyc
Ensembl Genes ENSRNOG00000024923 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000034166 ENTREZGENE
  ENSRNOT00000072502 ENTREZGENE
IMAGE_CLONE IMAGE:8364201 IMAGE-MGC_LOAD
InterPro Neuronatin UniProtKB/Swiss-Prot
KEGG Report rno:94270 UniProtKB/Swiss-Prot
MGC_CLONE MGC:156562 IMAGE-MGC_LOAD
NCBI Gene 94270 ENTREZGENE
PANTHER NEURONATIN UniProtKB/Swiss-Prot
  PTHR15285 UniProtKB/Swiss-Prot
PhenoGen Nnat PhenoGen
RatGTEx ENSRNOG00000024923 RatGTEx
UniProt A0A8I6AR75 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2QVS0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2UKY2 ENTREZGENE, UniProtKB/TrEMBL
  A0JPK6 ENTREZGENE
  A6JWT6_RAT UniProtKB/TrEMBL
  A6JWT7 ENTREZGENE, UniProtKB/TrEMBL
  A6JWT8 ENTREZGENE, UniProtKB/TrEMBL
  A6JWU0_RAT UniProtKB/TrEMBL
  NNAT_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q62663 ENTREZGENE
UniProt Secondary A0JPK6 UniProtKB/Swiss-Prot
  Q62663 UniProtKB/Swiss-Prot
1 to 25 of 25 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-02-26 Nnat  neuronatin      Symbol and Name status set to approved 625702 APPROVED
2002-08-07 Nnat  neuronatin      Symbol and Name status set to provisional 70820 PROVISIONAL

Note Type Note Reference
gene_expression preferentially found in vasopressin (VP)-expressing magnocellular neurons (MCNs) 628363
gene_expression expressed in thyroid tumors 628363
gene_expression strongly expressed in neonatal rat brain, with a subsequent decreased expression in juveniles and adults; expressed in endocrine cells, including pancreatic b-cells and PC-12 cells 628363
gene_homology homologous to PMP-1, an H+-ATPase subunit 628363
gene_mapping gene maps to distal chromosome 2 in an imprinting region where mutations can lead to developmental abnormalities 628363
gene_process may mediate regulation of ions during brain development 628363
gene_protein 54 and 81 kDa 628363
gene_protein 81 amino acids 729024
gene_regulation gene is paternally expressed and imprinted 628363
gene_transcript contains three exons producing two alternatively spliced mRNA 628363