Ralgapb (Ral GTPase activating protein non-catalytic subunit beta) - Rat Genome Database

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Gene: Ralgapb (Ral GTPase activating protein non-catalytic subunit beta) Rattus norvegicus
Analyze
Symbol: Ralgapb
Name: Ral GTPase activating protein non-catalytic subunit beta
RGD ID: 1306861
Description: Exhibits GTPase activator activity and protein heterodimerization activity. Involved in activation of GTPase activity. Orthologous to human RALGAPB (Ral GTPase activating protein non-catalytic subunit beta); INTERACTS WITH 17alpha-ethynylestradiol; bisphenol A; oxaliplatin.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC103691958; LOC362257; p170; Ral GTPase activating protein non-catalytic beta subunit; Ral GTPase activating protein, beta subunit (non-catalytic); Ral GTPase activating protein, beta subunit (non-catalytic)-like; ral GTPase-activating protein subunit beta; ral GTPase-activating protein subunit beta-like; RGD1306861; similar to RIKEN cDNA B230339M05 gene
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23147,062,443 - 147,152,090 (+)NCBI
Rnor_6.0 Ensembl3154,905,141 - 154,983,021 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.03154,910,291 - 154,983,021 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03160,623,751 - 160,696,177 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43149,137,224 - 149,212,377 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13149,031,561 - 149,118,099 (+)NCBI
Celera3145,780,077 - 145,852,667 (+)NCBICelera
Cytogenetic Map3q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

Additional References at PubMed
PMID:15057822   PMID:21148297  


Genomics

Comparative Map Data
Ralgapb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23147,062,443 - 147,152,090 (+)NCBI
Rnor_6.0 Ensembl3154,905,141 - 154,983,021 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.03154,910,291 - 154,983,021 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03160,623,751 - 160,696,177 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43149,137,224 - 149,212,377 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13149,031,561 - 149,118,099 (+)NCBI
Celera3145,780,077 - 145,852,667 (+)NCBICelera
Cytogenetic Map3q42NCBI
RALGAPB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2038,472,816 - 38,578,859 (+)EnsemblGRCh38hg38GRCh38
GRCh382038,472,820 - 38,578,861 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372037,101,486 - 37,207,501 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362036,534,900 - 36,640,918 (+)NCBINCBI36hg18NCBI36
Celera2033,812,295 - 33,918,296 (+)NCBI
Cytogenetic Map20q11.23NCBI
HuRef2033,838,335 - 33,944,354 (+)NCBIHuRef
CHM1_12037,005,683 - 37,111,714 (+)NCBICHM1_1
Ralgapb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392158,251,722 - 158,341,173 (+)NCBIGRCm39mm39
GRCm39 Ensembl2158,251,768 - 158,341,173 (+)Ensembl
GRCm382158,409,830 - 158,499,253 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2158,409,848 - 158,499,253 (+)EnsemblGRCm38mm10GRCm38
MGSCv372158,235,589 - 158,324,989 (+)NCBIGRCm37mm9NCBIm37
MGSCv362158,101,294 - 158,190,694 (+)NCBImm8
Celera2164,346,414 - 164,436,672 (+)NCBICelera
Cytogenetic Map2H1NCBI
Ralgapb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544518,140,944 - 18,241,128 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544518,146,316 - 18,241,128 (-)NCBIChiLan1.0ChiLan1.0
RALGAPB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12035,906,029 - 36,011,685 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2035,906,029 - 36,011,685 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02034,797,472 - 34,903,367 (+)NCBIMhudiblu_PPA_v0panPan3
RALGAPB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12426,948,626 - 27,032,092 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2426,961,628 - 27,070,850 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2426,594,210 - 26,677,570 (+)NCBI
ROS_Cfam_1.02427,645,025 - 27,728,261 (+)NCBI
UMICH_Zoey_3.12426,919,244 - 27,002,002 (+)NCBI
UNSW_CanFamBas_1.02427,027,094 - 27,110,307 (+)NCBI
UU_Cfam_GSD_1.02427,515,215 - 27,598,354 (+)NCBI
Ralgapb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640175,840,609 - 175,945,320 (+)NCBI
SpeTri2.0NW_0049365612,806,195 - 2,908,909 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RALGAPB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1741,507,806 - 41,606,898 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11741,507,756 - 41,606,903 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21746,951,706 - 47,014,116 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RALGAPB
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1225,177,380 - 25,285,938 (-)NCBI
ChlSab1.1 Ensembl225,176,956 - 25,307,991 (-)Ensembl
Ralgapb
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248421,067,651 - 1,167,779 (-)NCBI

Position Markers
RH130136  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23147,148,759 - 147,148,951 (+)MAPPER
Rnor_6.03154,979,691 - 154,979,882NCBIRnor6.0
Rnor_5.03160,626,890 - 160,627,081UniSTSRnor5.0
RGSC_v3.43149,212,086 - 149,212,277UniSTSRGSC3.4
Celera3145,849,337 - 145,849,528UniSTS
RH 3.4 Map31358.2UniSTS
Cytogenetic Map3q42UniSTS
RH142966  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23147,141,573 - 147,141,759 (+)MAPPER
Rnor_6.03154,972,506 - 154,972,691NCBIRnor6.0
Rnor_5.03160,634,081 - 160,634,266UniSTSRnor5.0
RGSC_v3.43149,204,901 - 149,205,086UniSTSRGSC3.4
Celera3145,842,150 - 145,842,335UniSTS
RH 3.4 Map31393.2UniSTS
Cytogenetic Map3q42UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)330846101172879276Rat
619618Rf3Renal disease susceptibility QTL 36.50.001urine albumin amount (VT:0002871)urine albumin excretion rate to body weight ratio (CMO:0001270)3114376250159376250Rat
1578656Vnigr2Vascular neointimal growth QTL 24.2artery morphology trait (VT:0002191)lesioned artery residual lumen area (CMO:0001417)3138374177177699992Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)345406058177699992Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)3103141944170934860Rat
1331726Bp208Blood pressure QTL 2083.129arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3148348517171467264Rat
1298068Bp167Blood pressure QTL 1670.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3150368003177699992Rat
631673Iddm13Insulin dependent diabetes mellitus QTL 131.30.663blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)3136876155170935007Rat
2312659Slep7Serum leptin concentration QTL 70.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)3103141814176418101Rat
2312670Bw94Body weight QTL 940.01inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)3103141814176418101Rat
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)3103141814176418101Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3138374177177699992Rat
2317883Alcrsp26Alcohol response QTL 261.80.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)3153918022177699992Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3129787213177699992Rat
1581568Rf53Renal function QTL 53total urine protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)358204463170534769Rat
1598854Memor10Memory QTL 102exploratory behavior trait (VT:0010471)average horizontal distance in proximity to the target during voluntary locomotion in an experimental apparatus (CMO:0002674)3153412455170534769Rat
1598877Bp285Blood pressure QTL 2851.50.03arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3128986468173986468Rat
2298477Eau4Experimental allergic uveoretinitis QTL 40.0011uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)3146232777177699992Rat
2301411Bp320Blood pressure QTL 3200.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3153381237174632112Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)399465522168732722Rat
1576306Schws3Schwannoma susceptibility QTL 30.001nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)3125848628170848628Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3119471263164471263Rat
1300113Bp176Blood pressure QTL 1763.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3153412455165355668Rat
1300159Kidm4Kidney mass QTL 43.83kidney mass (VT:0002707)right kidney wet weight to body weight ratio (CMO:0001953)3126575595165355668Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)343295930163640485Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)343295930163640485Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)348561928155263151Rat
2303620Vencon4Ventilatory control QTL 43.9respiration trait (VT:0001943)tidal volume (CMO:0000222)3132875075176418101Rat
2293087Iddm27Insulin dependent diabetes mellitus QTL 272.68blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)3102152812155263151Rat
61335Bp20Blood pressure QTL 203arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3148348739163640325Rat
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3139578365177699992Rat
8552791Vie2Viral induced encephalitis QTL 24.1brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)3153412455177699992Rat
8552952Pigfal13Plasma insulin-like growth factor 1 level QTL 13blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)3148034701177699992Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)361241033165369047Rat
12879874Cm98Cardiac mass QTL 980.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)3153381237174632112Rat
12879875Kidm64Kidney mass QTL 640.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3153381237174632112Rat
10755461Coatc16Coat color QTL 16coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)3130006659175006659Rat
12879871Am7Aortic mass QTL 70.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)3153381237174632112Rat
12879872Cm97Cardiac mass QTL 970.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3153381237174632112Rat
12879873Cm96Cardiac mass QTL 960.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)3153381237174632112Rat
12879876Bw182Body weight QTL 1820.003body mass (VT:0001259)body weight (CMO:0000012)3153381237174632112Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:46
Count of miRNA genes:43
Interacting mature miRNAs:46
Transcripts:ENSRNOT00000020556
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 40 40 24 19 24 8 8 74 35 41 11 8
Low 3 17 17 17 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000020556   ⟹   ENSRNOP00000020556
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl3154,905,149 - 154,979,408 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000079515   ⟹   ENSRNOP00000075270
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl3154,910,626 - 154,983,021 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000088748   ⟹   ENSRNOP00000071487
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl3154,905,141 - 154,983,016 (+)Ensembl
RefSeq Acc Id: NM_001271210   ⟹   NP_001258139
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23147,079,314 - 147,152,090 (+)NCBI
Rnor_6.03154,910,626 - 154,983,021 (+)NCBI
Rnor_5.03160,623,751 - 160,696,177 (-)NCBI
Celera3145,780,077 - 145,852,667 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006235415   ⟹   XP_006235477
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23147,062,443 - 147,152,087 (+)NCBI
Rnor_6.03154,910,291 - 154,983,018 (+)NCBI
Rnor_5.03160,623,751 - 160,696,177 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006235416   ⟹   XP_006235478
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23147,062,443 - 147,152,087 (+)NCBI
Rnor_6.03154,910,291 - 154,983,018 (+)NCBI
Rnor_5.03160,623,751 - 160,696,177 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006235417   ⟹   XP_006235479
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23147,062,443 - 147,152,087 (+)NCBI
Rnor_6.03154,910,291 - 154,983,018 (+)NCBI
Rnor_5.03160,623,751 - 160,696,177 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006235418   ⟹   XP_006235480
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23147,062,443 - 147,152,087 (+)NCBI
Rnor_6.03154,910,292 - 154,983,018 (+)NCBI
Rnor_5.03160,623,751 - 160,696,177 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006235420   ⟹   XP_006235482
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23147,062,444 - 147,152,087 (+)NCBI
Rnor_6.03154,910,292 - 154,983,018 (+)NCBI
Rnor_5.03160,623,751 - 160,696,177 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006235421   ⟹   XP_006235483
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23147,062,444 - 147,152,087 (+)NCBI
Rnor_6.03154,910,292 - 154,983,018 (+)NCBI
Rnor_5.03160,623,751 - 160,696,177 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008762357   ⟹   XP_008760579
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23147,062,443 - 147,152,087 (+)NCBI
Rnor_6.03154,910,291 - 154,983,018 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008762358   ⟹   XP_008760580
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23147,062,443 - 147,152,087 (+)NCBI
Rnor_6.03154,910,292 - 154,983,018 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039105506   ⟹   XP_038961434
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23147,063,039 - 147,152,087 (+)NCBI
RefSeq Acc Id: XM_039105507   ⟹   XP_038961435
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.23147,079,368 - 147,152,087 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_001258139   ⟸   NM_001271210
- UniProtKB: A0A0G2KA57 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006235480   ⟸   XM_006235418
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_006235478   ⟸   XM_006235416
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006235479   ⟸   XM_006235417
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006235477   ⟸   XM_006235415
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006235483   ⟸   XM_006235421
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: XP_006235482   ⟸   XM_006235420
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_008760579   ⟸   XM_008762357
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008760580   ⟸   XM_008762358
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: ENSRNOP00000075270   ⟸   ENSRNOT00000079515
RefSeq Acc Id: ENSRNOP00000020556   ⟸   ENSRNOT00000020556
RefSeq Acc Id: ENSRNOP00000071487   ⟸   ENSRNOT00000088748
RefSeq Acc Id: XP_038961434   ⟸   XM_039105506
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038961435   ⟸   XM_039105507
- Peptide Label: isoform X9
Protein Domains
Rap-GAP

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306861 AgrOrtholog
Ensembl Genes ENSRNOG00000014836 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000020556 UniProtKB/TrEMBL
  ENSRNOP00000071487 UniProtKB/TrEMBL
  ENSRNOP00000075270 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000020556 UniProtKB/TrEMBL
  ENSRNOT00000079515 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000088748 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.11210 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro RALGAPB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rap/Ran-GAP_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Rap_GAP_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:362257 UniProtKB/TrEMBL
NCBI Gene 362257 ENTREZGENE
PANTHER PTHR21344 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ralgapb PhenoGen
PROSITE RAPGAP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF111347 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K0K8_RAT UniProtKB/TrEMBL
  A0A0G2KA57 ENTREZGENE, UniProtKB/TrEMBL
  P86410 ENTREZGENE
  R9PXV2_RAT UniProtKB/TrEMBL
  RLGPB_RAT UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Ralgapb  Ral GTPase activating protein non-catalytic subunit beta  LOC103691958  ral GTPase-activating protein subunit beta-like  Data Merged 737654 PROVISIONAL
2019-12-06 Ralgapb  Ral GTPase activating protein non-catalytic subunit beta  Ralgapb  Ral GTPase activating protein non-catalytic beta subunit  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-02-03 Ralgapb  Ral GTPase activating protein non-catalytic beta subunit  Ralgapb  Ral GTPase activating protein, beta subunit (non-catalytic)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2014-08-25 LOC103691958  ral GTPase-activating protein subunit beta-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2013-05-24 Ralgapb  Ral GTPase activating protein, beta subunit (non-catalytic)  LOC100364646  Ral GTPase activating protein, beta subunit (non-catalytic)-like  Data Merged 1643240 APPROVED
2012-10-10 Ralgapb  Ral GTPase activating protein, beta subunit (non-catalytic)  RGD1306861  similar to RIKEN cDNA B230339M05 gene  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-05-05 LOC100364646  Ral GTPase activating protein, beta subunit (non-catalytic)-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 RGD1306861  similar to RIKEN cDNA B230339M05 gene   RGD1306861_predicted  similar to RIKEN cDNA B230339M05 gene (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-20 RGD1306861_predicted  similar to RIKEN cDNA B230339M05 gene (predicted)  LOC362257_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC362257_predicted  similar to RIKEN cDNA B230339M05 gene (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL