MMP9 (matrix metallopeptidase 9) - Rat Genome Database

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Gene: MMP9 (matrix metallopeptidase 9) Canis lupus familiaris
Analyze
Symbol: MMP9
Name: matrix metallopeptidase 9
RGD ID: 12288301
Description: ENCODES a protein that exhibits fibronectin binding (ortholog); metalloendopeptidase activity (ortholog); metallopeptidase activity (ortholog); INVOLVED IN apoptotic process (ortholog); cellular response to cell-matrix adhesion (ortholog); cellular response to cytokine stimulus (ortholog); PARTICIPATES IN fibroblast growth factor signaling pathway; syndecan signaling pathway; ASSOCIATED WITH abdominal aortic aneurysm (ortholog); Acute Coronary Syndrome (ortholog); Acute Lung Injury (ortholog); FOUND IN extracellular space (ortholog); protein-containing complex (ortholog); INTERACTS WITH dioxygen; hydrogen chloride; spironolactone
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 92 kDa gelatinase; 92 kDa type IV collagenase; gelatinase B; GELB; matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase); matrix metalloproteinase 9; matrix metalloproteinase-9; MMP-9; type IV collagenase MMP-9
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12433,274,260 - 33,281,116 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2433,274,268 - 33,281,293 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2432,801,110 - 32,807,958 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02433,984,592 - 33,991,450 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2433,984,589 - 33,991,650 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12433,242,837 - 33,249,697 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02433,358,136 - 33,364,990 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02433,897,331 - 33,904,192 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
abdominal aortic aneurysm  (ISO)
Acute Coronary Syndrome  (ISO)
Acute Lung Injury  (ISO)
Acute Otitis Media  (ISO)
adrenoleukodystrophy  (ISO)
adult respiratory distress syndrome  (ISO)
Albuminuria  (ISO)
alcohol use disorder  (ISO)
Alcoholic Liver Diseases  (ISO)
allergic contact dermatitis  (ISO)
Alveolar Bone Loss  (ISO)
Alzheimer's disease  (ISO)
amyotrophic lateral sclerosis  (ISO)
angle-closure glaucoma  (ISO)
Animal Disease Models  (ISO)
Animal Mammary Neoplasms  (ISO)
anodontia  (ISO)
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis  (ISO)
aortic aneurysm  (ISO)
aortic disease  (ISO)
aortic dissection  (ISO)
Aortic Rupture  (ISO)
Arterial Injury  (ISO)
arteriosclerosis  (ISO)
Arteriovenous Fistula  (ISO)
arteriovenous malformation  (ISO)
asthma  (ISO)
atopic dermatitis  (ISO)
atrial fibrillation  (ISO)
attention deficit hyperactivity disorder  (ISO)
autism spectrum disorder  (ISO)
autoimmune lymphoproliferative syndrome  (ISO)
autosomal dominant polycystic kidney disease  (ISO)
bacterial meningitis  (ISO)
bacterial pneumonia  (ISO)
Behcet's disease  (ISO)
Bone Neoplasms  (ISO)
brain edema  (ISO)
brain infarction  (ISO)
Brain Injuries  (ISO)
brain ischemia  (ISO)
Breast Neoplasms  (ISO)
Bronchial Hyperreactivity  (ISO)
bronchiectasis  (ISO)
bronchiolitis obliterans  (ISO)
bronchopulmonary dysplasia  (ISO)
bullous pemphigoid  (ISO)
Burns  (ISO)
CAKUT2  (ISO)
calcinosis  (ISO)
Cardiac Fibrosis  (ISO)
Cardiomegaly  (ISO)
cardiomyopathy  (ISO)
carotid artery disease  (ISO)
Carotid Artery Injuries  (ISO)
Carotid Atherosclerosis  (ISO)
Cerebral Hemorrhage  (ISO)
cerebral infarction  (ISO)
Chemical and Drug Induced Liver Injury  (ISO)
childhood absence epilepsy  (ISO)
cholangiocarcinoma  (ISO)
cholesteatoma  (ISO)
cholesteatoma of middle ear  (ISO)
chorioamnionitis  (ISO)
Choroidal Neovascularization  (ISO)
chronic inflammatory demyelinating polyradiculoneuropathy  (ISO)
chronic obstructive pulmonary disease  (ISO)
Chronic Periodontitis  (ISO)
chronic ulcer of skin  (ISO)
Cicatrix  (ISO)
cognitive disorder  (ISO)
colon adenocarcinoma  (ISO)
Colonic Neoplasms  (ISO)
colorectal cancer  (ISO)
Colorectal Neoplasms  (ISO)
congestive heart failure  (ISO)
conjunctivochalasis  (ISO)
coronary artery disease  (ISO)
crescentic glomerulonephritis  (ISO)
cystic fibrosis  (ISO)
dermatomyositis  (ISO)
Diabetic Foot  (ISO)
Diabetic Nephropathies  (ISO)
diabetic neuropathy  (ISO)
diabetic retinopathy  (ISO)
Disease Progression  (ISO)
Down syndrome  (ISO)
Duchenne muscular dystrophy  (ISO)
ductal carcinoma in situ  (ISO)
Embolism  (ISO)
Emphysema  (ISO)
endometrial carcinoma  (ISO)
endometriosis  (ISO)
epidermolysis bullosa simplex  (ISO)
epilepsy  (ISO)
esophagus adenocarcinoma  (ISO)
esophagus squamous cell carcinoma  (ISO)
exfoliation syndrome  (ISO)
Experimental Arthritis  (ISO)
Experimental Autoimmune Encephalomyelitis  (ISO)
Experimental Autoimmune Neuritis  (ISO)
Experimental Colitis  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Liver Cirrhosis  (ISO)
Experimental Liver Neoplasms  (ISO)
Experimental Mammary Neoplasms  (ISO)
extrahepatic cholestasis  (ISO)
facial paralysis  (ISO)
familial hyperlipidemia  (ISO)
Febrile Seizures  (ISO)
Fibrosis  (ISO)
Focal Cortical Dysplasia of Taylor  (ISO)
focal epilepsy  (ISO)
focal segmental glomerulosclerosis  (ISO)
fragile X syndrome  (ISO)
gastric ulcer  (ISO)
genetic disease  (ISO)
glaucoma  (ISO)
glioblastoma  (ISO)
glomerulosclerosis  (ISO)
Gouty Arthritis  (ISO)
heart valve disease  (ISO)
Hemorrhagic Shock  (ISO)
hepatic veno-occlusive disease  (ISO)
hepatocellular carcinoma  (ISO)
Herpes Simplex Encephalitis  (ISO)
Human Influenza  (ISO)
Huntington's disease  (ISO)
hyperglycemia  (ISO)
hyperhomocysteinemia  (ISO)
Hyperlipoproteinemia Type II  (ISO)
Hyperoxia  (ISO)
Hyperoxic Lung Injury  (ISO)
Hyperplasia  (ISO)
hypertension  (ISO)
hypertrophic cardiomyopathy  (ISO)
ileus  (ISO)
Inflammation  (ISO)
interstitial lung disease  (ISO)
intracranial aneurysm  (ISO)
ischemia  (ISO)
Kawasaki disease  (ISO)
kidney disease  (ISO)
Laryngeal Neoplasms  (ISO)
Lead Poisoning  (ISO)
liver disease  (ISO)
Liver Injury  (ISO)
Liver Reperfusion Injury  (ISO)
lung disease  (ISO)
Lung Neoplasms  (ISO)
lung non-small cell carcinoma  (ISO)
Lung Reperfusion Injury  (ISO)
lupus nephritis  (ISO)
lymphangioleiomyomatosis  (ISO)
Lymphatic Metastasis  (ISO)
macular degeneration  (ISO)
malignant astrocytoma  (ISO)
Malignant Pleural Effusions  (ISO)
mandibuloacral dysplasia type A lipodystrophy  (ISO)
Marfan syndrome  (ISO)
membranous glomerulonephritis  (ISO)
meningococcal meningitis  (ISO)
Metaphyseal Anadysplasia  (ISO)
Metaphyseal Anadysplasia 2  (ISO)
middle cerebral artery infarction  (ISO)
morphine dependence  (ISO)
Multiple Organ Failure  (ISO)
multiple sclerosis  (ISO)
Mycoplasma Infections  (ISO)
myocardial infarction  (ISO)
myocarditis  (ISO)
Nasal Polyps  (ISO)
Neointima  (ISO)
Neoplasm Invasiveness  (ISO)
Neoplasm Metastasis  (ISO)
Neoplastic Cell Transformation  (ISO)
Nephrogenic Fibrosing Dermopathy  (ISO)
neuroblastoma  (ISO)
neuromyelitis optica  (ISO)
obesity  (ISO)
obstructive sleep apnea  (ISO)
ocular hypertension  (ISO)
oral submucous fibrosis  (ISO)
osteoarthritis  (ISO)
osteoporosis  (ISO)
pancreatic cancer  (ISO)
pancreatic ductal carcinoma  (ISO)
paracoccidioidomycosis  (ISO)
Parkinsonism  (ISO)
Pathologic Constriction  (ISO)
Perennial Allergic Rhinitis  (ISO)
periodontitis  (ISO)
pleural tuberculosis  (ISO)
Pneumococcal Meningitis  (ISO)
pneumonia  (ISO)
polymyositis  (ISO)
Polypoidal Choroidal Vasculopathy  (ISO)
pre-eclampsia  (ISO)
Premature Birth  (ISO)
primary biliary cholangitis  (ISO)
primary open angle glaucoma  (ISO)
primary progressive multiple sclerosis  (ISO)
Prostatic Neoplasms  (ISO)
Pseudomonas Aeruginosa Keratitis  (ISO)
pterygium  (ISO)
pulmonary embolism  (ISO)
pulmonary emphysema  (ISO)
pulmonary fibrosis  (ISO)
pulmonary hypertension  (ISO)
pulmonary tuberculosis  (ISO)
pyoderma gangrenosum  (ISO)
relapsing-remitting multiple sclerosis  (ISO)
renal cell carcinoma  (ISO)
renal fibrosis  (ISO)
renal hypertension  (ISO)
Reperfusion Injury  (ISO)
Respiratory Sounds  (ISO)
respiratory syncytial virus infectious disease  (ISO)
Respirovirus Infections  (ISO)
retinal disease  (ISO)
retinal ischemia  (ISO)
rheumatic heart disease  (ISO)
rheumatoid arthritis  (ISO)
Rhinosinusitis  (ISO)
Right Ventricular Hypertrophy  (ISO)
rosacea  (ISO)
sciatic neuropathy  (ISO)
Seasonal Allergic Rhinitis  (ISO)
Sepsis  (ISO)
sinusitis  (ISO)
Sjogren's syndrome  (ISO)
skin melanoma  (ISO)
Skin Neoplasms  (ISO)
Spinal Cord Injuries  (ISO)
squamous cell carcinoma  (ISO)
Stable Angina  (ISO)
status epilepticus  (ISO)
stomach cancer  (ISO)
stomach carcinoma  (ISO)
Stroke  (ISO)
Sturge-Weber syndrome  (ISO)
Subarachnoid Hemorrhage  (ISO)
Sunburn  (ISO)
Sweet syndrome  (ISO)
systemic scleroderma  (ISO)
T-Cell Immunodeficiency, Recurrent Infections, and Autoimmunity with or without Cardiac Malformations  (ISO)
Tachycardia, Atrioventricular Nodal Reentry  (ISO)
Takayasu's arteritis  (ISO)
temporal arteritis  (ISO)
temporal lobe epilepsy  (ISO)
thoracic aortic aneurysm  (ISO)
thrombosis  (ISO)
tongue squamous cell carcinoma  (ISO)
transient cerebral ischemia  (ISO)
traumatic brain injury  (ISO)
tuberous sclerosis  (ISO)
tularemia  (ISO)
type 1 diabetes mellitus  (ISO)
type 2 diabetes mellitus  (ISO)
ulcerative colitis  (ISO)
urinary bladder cancer  (ISO)
varicose veins  (ISO)
Venous Thrombosis  (ISO)
ventricular septal defect  (ISO)
viral encephalitis  (ISO)
withdrawal disorder  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
apoptotic process  (IEA,ISO)
cell migration  (IEA)
cellular response to cadmium ion  (IEA)
cellular response to cell-matrix adhesion  (ISO)
cellular response to cytokine stimulus  (ISO)
cellular response to interleukin-1  (ISO)
cellular response to iron(III) ion  (ISO)
cellular response to lipopolysaccharide  (ISO)
cellular response to low-density lipoprotein particle stimulus  (ISO)
cellular response to reactive oxygen species  (IEA)
cellular response to tumor necrosis factor  (ISO)
cellular response to UV-A  (IEA)
collagen catabolic process  (IBA,IEA,ISO)
embryo implantation  (IEA,ISO)
endodermal cell differentiation  (IEA)
extracellular matrix organization  (IBA,IEA,ISO)
heart development  (ISO)
kidney development  (ISO)
macrophage chemotaxis  (ISO)
negative regulation of apoptotic process  (IEA)
negative regulation of epithelial cell differentiation involved in kidney development  (IEA)
negative regulation of fibroblast proliferation  (ISO)
negative regulation of intrinsic apoptotic signaling pathway  (IEA)
ossification  (ISO)
parturition  (ISO)
positive regulation of angiogenesis  (ISO)
positive regulation of apoptotic process  (IEA,ISO)
positive regulation of epidermal growth factor receptor signaling pathway  (IEA)
positive regulation of keratinocyte migration  (IEA)
positive regulation of leukocyte migration  (ISO)
positive regulation of protein phosphorylation  (IEA)
positive regulation of release of cytochrome c from mitochondria  (IEA)
positive regulation of synaptic plasticity  (ISO)
positive regulation of vascular associated smooth muscle cell proliferation  (IEA)
protein catabolic process  (ISO)
proteolysis  (IEA,ISO,ISS)
response to amyloid-beta  (IEA)
response to estradiol  (ISO)
response to ethanol  (ISO)
response to high light intensity  (ISO)
response to hyperoxia  (ISO)
response to hypoxia  (ISO)
response to lipopolysaccharide  (ISO)
response to mechanical stimulus  (ISO)
response to nicotine  (ISO)
response to nutrient  (ISO)
response to organic cyclic compound  (ISO)
response to organic substance  (ISO)
response to oxidative stress  (ISO)
response to retinoic acid  (ISO)
response to tumor necrosis factor  (ISO)
response to vitamin A  (ISO)
response to xenobiotic stimulus  (ISO)
skeletal system development  (IEA,ISO)
tissue remodeling  (ISO)
transformation of host cell by virus  (ISO)

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:9325284   PMID:11483363   PMID:11731079   PMID:15486029   PMID:16454634   PMID:17598883   PMID:17669022   PMID:17911518   PMID:17913363   PMID:18047836   PMID:18368598   PMID:18706834  
PMID:18712173   PMID:19150571   PMID:20477983   PMID:20965533   PMID:21526488   PMID:21801058   PMID:21801067   PMID:22167104   PMID:22301074   PMID:22440362   PMID:22489798   PMID:22520817  
PMID:22533401   PMID:23639293   PMID:27069163   PMID:27859764   PMID:28296543   PMID:29671048   PMID:30032202   PMID:30206048   PMID:31050171   PMID:31269334  


Genomics

Comparative Map Data
MMP9
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12433,274,260 - 33,281,116 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2433,274,268 - 33,281,293 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2432,801,110 - 32,807,958 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02433,984,592 - 33,991,450 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2433,984,589 - 33,991,650 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12433,242,837 - 33,249,697 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02433,358,136 - 33,364,990 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02433,897,331 - 33,904,192 (+)NCBIUU_Cfam_GSD_1.0
MMP9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382046,008,908 - 46,016,561 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2046,008,908 - 46,016,561 (+)EnsemblGRCh38hg38GRCh38
GRCh372044,637,547 - 44,645,200 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362044,070,954 - 44,078,607 (+)NCBINCBI36Build 36hg18NCBI36
Build 342044,070,953 - 44,078,606NCBI
Celera2041,348,998 - 41,356,660 (+)NCBICelera
Cytogenetic Map20q13.12NCBI
HuRef2041,378,970 - 41,386,505 (+)NCBIHuRef
CHM1_12044,540,180 - 44,547,844 (+)NCBICHM1_1
T2T-CHM13v2.02047,744,921 - 47,752,589 (+)NCBIT2T-CHM13v2.0
Mmp9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392164,782,246 - 164,797,770 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2164,782,700 - 164,797,770 (+)EnsemblGRCm39 Ensembl
GRCm382164,940,326 - 164,955,850 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2164,940,780 - 164,955,850 (+)EnsemblGRCm38mm10GRCm38
MGSCv372164,773,751 - 164,781,346 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362164,639,456 - 164,647,051 (+)NCBIMGSCv36mm8
Celera2170,885,579 - 170,893,176 (+)NCBICelera
Cytogenetic Map2H3NCBI
cM Map285.27NCBI
Mmp9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83174,103,474 - 174,111,434 (+)NCBIGRCr8
mRatBN7.23153,684,158 - 153,692,118 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3153,683,858 - 153,692,120 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3157,492,813 - 157,500,796 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03165,991,783 - 165,999,766 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03163,735,564 - 163,743,543 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03161,413,410 - 161,421,473 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3161,413,298 - 161,421,520 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03167,578,904 - 167,605,890 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43155,985,473 - 155,993,433 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13155,891,508 - 155,899,467 (+)NCBI
Celera3152,289,466 - 152,297,426 (+)NCBICelera
Cytogenetic Map3q42NCBI
Mmp9
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544511,295,448 - 11,303,288 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544511,295,500 - 11,303,322 (-)NCBIChiLan1.0ChiLan1.0
MMP9
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22151,748,843 - 51,757,462 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12051,741,951 - 51,749,613 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02042,346,305 - 42,354,018 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12043,432,389 - 43,440,129 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2043,432,389 - 43,440,129 (+)Ensemblpanpan1.1panPan2
Mmp9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640191,584,597 - 191,592,230 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365147,037,639 - 7,045,793 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365147,038,240 - 7,045,873 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MMP9
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1748,179,671 - 48,186,788 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11748,179,690 - 48,186,782 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21753,819,971 - 53,827,064 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MMP9
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1217,867,267 - 17,874,757 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl217,867,177 - 17,874,712 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605066,502,195 - 66,509,744 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mmp9
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247908,583,457 - 8,591,713 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247908,584,399 - 8,591,763 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in MMP9
78 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium
Low 1 1
Below cutoff 5 3 20 6 6 6 5 2 11 7 10 6

Sequence


RefSeq Acc Id: ENSCAFT00000015753   ⟹   ENSCAFP00000014582
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2433,274,268 - 33,281,293 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000039331   ⟹   ENSCAFP00000035167
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2433,274,268 - 33,281,293 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845031190   ⟹   ENSCAFP00845024418
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2433,984,589 - 33,991,650 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845031310   ⟹   ENSCAFP00845024511
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2433,984,592 - 33,991,635 (+)Ensembl
RefSeq Acc Id: NM_001003219   ⟹   NP_001003219
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12433,274,260 - 33,281,116 (+)NCBI
Dog10K_Boxer_Tasha2432,801,110 - 32,807,958 (+)NCBI
ROS_Cfam_1.02433,984,592 - 33,991,450 (+)NCBI
UMICH_Zoey_3.12433,242,837 - 33,249,697 (+)NCBI
UNSW_CanFamBas_1.02433,358,136 - 33,364,990 (+)NCBI
UU_Cfam_GSD_1.02433,897,331 - 33,904,192 (+)NCBI
Sequence:
RefSeq Acc Id: NP_001003219   ⟸   NM_001003219
- Peptide Label: precursor
- UniProtKB: O19130 (UniProtKB/Swiss-Prot),   O18733 (UniProtKB/Swiss-Prot),   Q71U09 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000035167   ⟸   ENSCAFT00000039331
RefSeq Acc Id: ENSCAFP00000014582   ⟸   ENSCAFT00000015753
RefSeq Acc Id: ENSCAFP00845024511   ⟸   ENSCAFT00845031310
RefSeq Acc Id: ENSCAFP00845024418   ⟸   ENSCAFT00845031190
Protein Domains
Fibronectin type-II

Promoters
RGD ID:13687640
Promoter ID:EPDNEW_C5709
Type:multiple initiation site
Name:MMP9_1
Description:matrix metallopeptidase 9
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12433,274,249 - 33,274,309EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000009905 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030018463 UniProtKB/TrEMBL
  ENSCAFG00040005864 UniProtKB/TrEMBL
  ENSCAFG00845017615 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000015753.4 UniProtKB/TrEMBL
  ENSCAFT00000039331.5 UniProtKB/TrEMBL
  ENSCAFT00030034021.1 UniProtKB/TrEMBL
  ENSCAFT00030034136.1 UniProtKB/TrEMBL
  ENSCAFT00040010989.1 UniProtKB/TrEMBL
  ENSCAFT00040011003.1 UniProtKB/TrEMBL
  ENSCAFT00040011043.1 UniProtKB/TrEMBL
  ENSCAFT00845031190.1 UniProtKB/TrEMBL
  ENSCAFT00845031310 ENTREZGENE
  ENSCAFT00845031310.1 UniProtKB/TrEMBL
Gene3D-CATH 2.10.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.110.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.390.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro FN_type2_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FN_type2_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hemopexin-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hemopexin-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hemopexin-like_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hemopexin_CS UniProtKB/TrEMBL
  IPR006970 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kringle-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  M10A_MMP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MetalloPept_cat_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pept_M10_metallopeptidase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pept_M10A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pept_M10A_Zn_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_Metallo UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PGBD-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report cfa:403885 UniProtKB/TrEMBL
NCBI Gene MMP9 ENTREZGENE
PANTHER MATRIX METALLOPROTEINASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10201:SF30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam fn2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hemopexin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_M10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PF04886 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PIRSF Peptidase_M10A_matrix UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS FNTYPEII UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MATRIXIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE CYSTEINE_SWITCH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FN2_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FN2_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HEMOPEXIN UniProtKB/TrEMBL
  HEMOPEXIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROKAR_LIPOPROTEIN UniProtKB/TrEMBL
  ZINC_PROTEASE UniProtKB/Swiss-Prot
SMART FN2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00120 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZnMc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Metalloproteases ('zincins'), catalytic domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF47090 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF50923 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF57440 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8C0NSU6_CANLF UniProtKB/TrEMBL
  A0A8C0Q755_CANLF UniProtKB/TrEMBL
  A0A8C0Q774_CANLF UniProtKB/TrEMBL
  A0A8C0QDY8_CANLF UniProtKB/TrEMBL
  A0A8I3P478_CANLF UniProtKB/TrEMBL
  A0A8I3S2Q7_CANLF UniProtKB/TrEMBL
  MMP9_CANLF UniProtKB/Swiss-Prot, ENTREZGENE
  O19130 ENTREZGENE
  Q71U09 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary O19130 UniProtKB/Swiss-Prot
VGNC ID VGNC:43290 ENTREZGENE