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Gene: Lcn2 (lipocalin 2) Rattus norvegicus
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Symbol: Lcn2
Name: lipocalin 2
Description: Exhibits protease binding activity and protein homodimerization activity. Involved in several processes, including cellular response to cytokine stimulus; cellular response to lipopolysaccharide; and protein homotrimerization. Localizes to the cytosol and extracellular space. Biomarker of acute kidney failure; colon cancer; myocarditis; and obesity. Orthologous to human LCN2 (lipocalin 2); INTERACTS WITH (+)-schisandrin B; (-)-citrinin; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: alpha-2-microglobulin-related protein; alpha-2U globulin-related protein; lipocalin 2 (oncogene 24p3); lipocalin 24p3; lipocalin-2; neutrophil gelatinase-associated lipocalin; NGAL; p25; siderocalin LCN2; Sip24
Orthologs:
Homo sapiens (human) : LCN2 (lipocalin 2)  HGNC  Alliance
Mus musculus (house mouse) : Lcn2 (lipocalin 2)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : LCN2 (lipocalin 2)
Canis lupus familiaris (dog) : LCN2 (lipocalin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lcn2 (lipocalin 2)
Sus scrofa (pig) : LCN2 (lipocalin 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0311,414,189 - 11,417,534 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0316,763,059 - 16,766,404 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4311,511,402 - 11,514,747 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1311,407,773 - 11,411,119 (-)NCBI
Celera310,423,569 - 10,426,914 (-)NCBICelera
Cytogenetic Map3p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Lcn2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69408
Created: 2001-11-27
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.