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Gene: Ube3a (ubiquitin protein ligase E3A) Rattus norvegicus
Symbol: Ube3a
Name: ubiquitin protein ligase E3A
RGD ID: 1306361
Description: Predicted to have transcription coactivator activity and ubiquitin protein ligase activity. Involved in several processes, including cellular response to brain-derived neurotrophic factor stimulus; negative regulation of dendritic spine morphogenesis; and positive regulation of Golgi lumen acidification. Predicted to localize to cytosol and nucleus. Human ortholog(s) of this gene implicated in Angelman syndrome. Orthologous to human UBE3A (ubiquitin protein ligase E3A); PARTICIPATES IN ubiquitin/proteasome degradation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A.
Type: protein-coding
RefSeq Status: INFERRED
Also known as: LOC361585; ubiquitin-protein ligase E3A
Homo sapiens (human) : UBE3A (ubiquitin protein ligase E3A)  HGNC  Alliance
Mus musculus (house mouse) : Ube3a (ubiquitin protein ligase E3A)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ube3a (ubiquitin protein ligase E3A)
Pan paniscus (bonobo/pygmy chimpanzee) : UBE3A (ubiquitin protein ligase E3A)
Canis lupus familiaris (dog) : UBE3A (ubiquitin protein ligase E3A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ube3a (ubiquitin protein ligase E3A)
Sus scrofa (pig) : UBE3A (ubiquitin protein ligase E3A)
Chlorocebus sabaeus (African green monkey) : UBE3A (ubiquitin protein ligase E3A)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01116,586,901 - 116,678,161 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1116,587,815 - 116,679,973 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01117,745,283 - 117,834,011 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41110,729,142 - 110,816,491 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11110,807,819 - 110,893,065 (+)NCBI
Celera1104,203,680 - 104,290,036 (+)NCBICelera
Cytogenetic Map1q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Ube3a
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1306361
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.