Gene: Diaph3 (diaphanous-related formin 3) Rattus norvegicus
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Symbol: Diaph3
Name: diaphanous-related formin 3
Description: ENCODES a protein that exhibits actin binding (inferred); Rho GTPase binding (inferred); INVOLVED IN spermatogenesis; actin cytoskeleton organization (ortholog); actin filament polymerization (ortholog); ASSOCIATED WITH autosomal dominant auditory neuropathy 1 (ortholog); Chromosome 13q Deletion Syndrome (ortholog); chromosome 13q14 deletion syndrome (ortholog); FOUND IN cytoplasm; nucleus; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 6-propyl-2-thiouracil; acrylamide
AGR Description: Predicted to have Rho GTPase binding activity and actin binding activity; involved in spermatogenesis; localizes to the cytoplasm and nucleus; orthologous to human DIAPH3 (diaphanous related formin 3).
Merged Description: Predicted to have Rho GTPase binding activity and actin binding activity; involved in spermatogenesis; localizes to the cytoplasm and nucleus; orthologous to human DIAPH3 (diaphanous related formin 3); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 6-propyl-2-thiouracil; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Diap3; diaphanous homolog 3; diaphanous homolog 3 (Drosophila); DRF3; LOC290396; mDIA2; similar to Protein diaphanous homolog 3 (Diaphanous-related formin-3) (DRF3) (mDIA2) (p134mDIA2)
Orthologs:
Homo sapiens (human) : DIAPH3 (diaphanous related formin 3)  HGNC  Alliance
Mus musculus (house mouse) : Diaph3 (diaphanous related formin 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Diaph3 (diaphanous related formin 3)
Pan paniscus (bonobo/pygmy chimpanzee) : DIAPH3 (diaphanous related formin 3)
Canis lupus familiaris (dog) : DIAPH3 (diaphanous related formin 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Diaph3 (diaphanous related formin 3)
Sus scrofa (pig) : DIAPH3 (diaphanous related formin 3)
more info ...
Allele / Splice: Diaph3Tn(sb-T2/Bart3)2.318Mcwi  
Genetic Models: F344-Diaph3Tn(sb-T2/Bart3)2.318Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01569,928,507 - 70,400,077 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01573,538,942 - 74,007,617 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41568,905,784 - 69,267,707 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1562,058,201 - 62,525,728 (-)NCBICelera
Cytogenetic Map15q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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Genomics

Comparative Map Data
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QTLs in Region (Rnor_6.0)
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Sequence

Nucleotide Sequences
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Strain Variation

Strain Sequence Variants (Rnor 5.0)
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Additional Information

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Nomenclature History
  
More on Diaph3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1593287
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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