(-)-epigallocatechin 3-gallate multiple interactions ISO RGD:1350370 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of DIAPH3 mRNA CTD PMID:22079256 1-naphthyl isothiocyanate increases expression EXP 6480464 1-Naphthylisothiocyanate results in increased expression of DIAPH3 mRNA CTD PMID:30723492 17alpha-ethynylestradiol affects expression ISO RGD:1314906 6480464 Ethinyl Estradiol affects the expression of DIAPH3 mRNA CTD PMID:17555576 17alpha-ethynylestradiol multiple interactions ISO RGD:1314906 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of DIAPH3 mRNA CTD PMID:17942748 17alpha-ethynylestradiol increases expression ISO RGD:1314906 6480464 Ethinyl Estradiol results in increased expression of DIAPH3 mRNA CTD PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1350370 6480464 Tetrachlorodibenzodioxin affects the expression of DIAPH3 mRNA CTD PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of DIAPH3 mRNA CTD PMID:32109520 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1314906 6480464 Tetrachlorodibenzodioxin affects the expression of DIAPH3 mRNA CTD PMID:21570461 , PMID:26377647 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1314906 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of DIAPH3 mRNA CTD PMID:17942748 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:1350370 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of DIAPH3 mRNA CTD PMID:28628672 4,4'-sulfonyldiphenol multiple interactions ISO RGD:1350370 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of DIAPH3 mRNA CTD PMID:28628672 6-propyl-2-thiouracil increases expression EXP 6480464 Propylthiouracil results in increased expression of DIAPH3 mRNA CTD PMID:24780913 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of DIAPH3 mRNA CTD PMID:24780913 , PMID:25825206 acetamide increases expression EXP 6480464 acetamide results in increased expression of DIAPH3 mRNA CTD PMID:31881176 acrylamide increases expression EXP 6480464 Acrylamide results in increased expression of DIAPH3 mRNA CTD PMID:28959563 aflatoxin B1 affects expression ISO RGD:1350370 6480464 Aflatoxin B1 affects the expression of DIAPH3 protein CTD PMID:20106945 aflatoxin B1 decreases methylation ISO RGD:1350370 6480464 Aflatoxin B1 results in decreased methylation of DIAPH3 gene CTD PMID:27153756 aflatoxin B1 increases expression ISO RGD:1350370 6480464 Aflatoxin B1 results in increased expression of DIAPH3 mRNA CTD PMID:27153756 arsenous acid increases expression ISO RGD:1350370 6480464 Arsenic Trioxide results in increased expression of DIAPH3 mRNA CTD PMID:20458559 atrazine increases expression ISO RGD:1350370 6480464 Atrazine results in increased expression of DIAPH3 mRNA CTD PMID:22378314 azathioprine decreases expression ISO RGD:1350370 6480464 Azathioprine results in decreased expression of DIAPH3 mRNA CTD PMID:22623647 benzo[a]pyrene decreases expression ISO RGD:1350370 6480464 Benzo(a)pyrene results in decreased expression of DIAPH3 mRNA CTD PMID:20106945 more ... benzo[a]pyrene decreases expression ISO RGD:1314906 6480464 Benzo(a)pyrene results in decreased expression of DIAPH3 mRNA CTD PMID:15034205 benzo[a]pyrene multiple interactions ISO RGD:1314906 6480464 AHR protein promotes the reaction [Benzo(a)pyrene results in decreased expression of DIAPH3 mRNA] CTD PMID:15034205 benzo[a]pyrene diol epoxide I decreases expression ISO RGD:1350370 6480464 7 more ... CTD PMID:19150397 , PMID:20382639 benzo[b]fluoranthene increases expression ISO RGD:1314906 6480464 benzo(b)fluoranthene results in increased expression of DIAPH3 mRNA CTD PMID:26377693 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of DIAPH3 mRNA CTD PMID:25181051 bisphenol A decreases expression ISO RGD:1350370 6480464 bisphenol A results in decreased expression of DIAPH3 mRNA CTD PMID:29275510 calcitriol decreases expression ISO RGD:1350370 6480464 Calcitriol results in decreased expression of DIAPH3 mRNA CTD PMID:21592394 calcitriol multiple interactions ISO RGD:1350370 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of DIAPH3 mRNA CTD PMID:21592394 carbon nanotube increases expression ISO RGD:1314906 6480464 Nanotubes, Carbon analog results in increased expression of DIAPH3 mRNA, Nanotubes, Carbon results in increased expression of DIAPH3 mRNA CTD PMID:25554681 chromium(6+) decreases expression ISO RGD:1350370 6480464 chromium hexavalent ion results in decreased expression of DIAPH3 mRNA CTD PMID:30690063 cisplatin decreases expression EXP 6480464 Cisplatin results in decreased expression of DIAPH3 mRNA CTD PMID:22023808 cisplatin multiple interactions ISO RGD:1350370 6480464 [Cisplatin co-treated with jinfukang] results in decreased expression of DIAPH3 mRNA CTD PMID:27392435 cisplatin decreases expression ISO RGD:1350370 6480464 Cisplatin results in decreased expression of DIAPH3 mRNA CTD PMID:27392435 copper(II) sulfate increases expression ISO RGD:1350370 6480464 Copper Sulfate results in increased expression of DIAPH3 mRNA CTD PMID:19549813 coumestrol multiple interactions ISO RGD:1350370 6480464 [Coumestrol co-treated with 2 more ... CTD PMID:19167446 cyclosporin A increases expression ISO RGD:1350370 6480464 Cyclosporine results in increased expression of DIAPH3 mRNA CTD PMID:25562108 cyclosporin A decreases expression ISO RGD:1350370 6480464 Cyclosporine results in decreased expression of DIAPH3 mRNA CTD PMID:27989131 dexamethasone multiple interactions ISO RGD:1350370 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of DIAPH3 mRNA CTD PMID:28628672 diarsenic trioxide increases expression ISO RGD:1350370 6480464 Arsenic Trioxide results in increased expression of DIAPH3 mRNA CTD PMID:20458559 dioxygen multiple interactions ISO RGD:1314906 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of DIAPH3 mRNA CTD PMID:30529165 Enterolactone multiple interactions ISO RGD:1350370 6480464 [Coumestrol co-treated with 2, 3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of DIAPH3 mRNA CTD PMID:19167446 enzyme inhibitor multiple interactions ISO RGD:1350370 6480464 [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of DIAPH3 protein CTD PMID:23301498 ethyl methanesulfonate increases expression ISO RGD:1350370 6480464 Ethyl Methanesulfonate results in increased expression of DIAPH3 mRNA CTD PMID:23649840 formaldehyde decreases expression ISO RGD:1350370 6480464 Formaldehyde results in decreased expression of DIAPH3 mRNA CTD PMID:23649840 indole-3-methanol multiple interactions EXP 6480464 [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of DIAPH3 mRNA CTD PMID:22129741 indometacin multiple interactions ISO RGD:1350370 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of DIAPH3 mRNA CTD PMID:28628672 leflunomide increases expression ISO RGD:1314906 6480464 leflunomide results in increased expression of DIAPH3 mRNA CTD PMID:19751817 lucanthone decreases expression ISO RGD:1350370 6480464 Lucanthone results in decreased expression of DIAPH3 mRNA CTD PMID:21148553 MeIQx increases expression ISO RGD:1350370 6480464 2-amino-3 more ... CTD PMID:20816883 methamphetamine decreases expression EXP 6480464 Methamphetamine results in decreased expression of DIAPH3 mRNA CTD PMID:28341135 methapyrilene decreases expression EXP 6480464 Methapyrilene results in decreased expression of DIAPH3 mRNA CTD PMID:30467583 methotrexate affects expression ISO RGD:1314906 6480464 Methotrexate affects the expression of DIAPH3 mRNA CTD PMID:18502557 methyl methanesulfonate increases expression ISO RGD:1350370 6480464 Methyl Methanesulfonate results in increased expression of DIAPH3 mRNA CTD PMID:23649840 methylmercury chloride increases expression ISO RGD:1350370 6480464 methylmercuric chloride results in increased expression of DIAPH3 mRNA CTD PMID:28001369 N-methyl-4-phenylpyridinium decreases expression ISO RGD:1350370 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of DIAPH3 mRNA CTD PMID:24810058 N-nitrosodiethylamine multiple interactions EXP 6480464 [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of DIAPH3 mRNA CTD PMID:22129741 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of DIAPH3 mRNA CTD PMID:25729387 oxaliplatin decreases expression EXP 6480464 oxaliplatin results in decreased expression of DIAPH3 mRNA CTD PMID:25729387 paracetamol increases expression ISO RGD:1350370 6480464 Acetaminophen results in increased expression of DIAPH3 mRNA CTD PMID:22230336 paracetamol decreases expression ISO RGD:1350370 6480464 Acetaminophen results in decreased expression of DIAPH3 mRNA CTD PMID:29067470 phenformin decreases expression EXP 6480464 Phenformin results in decreased expression of DIAPH3 mRNA CTD PMID:31324951 PhIP increases expression ISO RGD:1350370 6480464 2-amino-1-methyl-6-phenylimidazo(4, 5-b)pyridine results in increased expression of DIAPH3 mRNA CTD PMID:20816883 pirinixic acid decreases expression ISO RGD:1314906 6480464 pirinixic acid results in decreased expression of DIAPH3 mRNA CTD PMID:20813756 potassium chromate multiple interactions ISO RGD:1350370 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of DIAPH3 mRNA CTD PMID:22079256 potassium chromate decreases expression ISO RGD:1350370 6480464 potassium chromate(VI) results in decreased expression of DIAPH3 mRNA CTD PMID:22079256 , PMID:22714537 potassium dichromate decreases expression ISO RGD:1350370 6480464 Potassium Dichromate results in decreased expression of DIAPH3 protein CTD PMID:23718831 progesterone decreases expression ISO RGD:1350370 6480464 Progesterone results in decreased expression of DIAPH3 mRNA CTD PMID:21795739 propanal decreases expression ISO RGD:1350370 6480464 propionaldehyde results in decreased expression of DIAPH3 mRNA CTD PMID:26079696 resveratrol multiple interactions ISO RGD:1350370 6480464 [Coumestrol co-treated with resveratrol] results in increased expression of DIAPH3 mRNA CTD PMID:19167446 rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of DIAPH3 mRNA CTD PMID:28374803 silicon dioxide decreases expression ISO RGD:1350370 6480464 Silicon Dioxide analog results in decreased expression of DIAPH3 mRNA CTD PMID:23806026 , PMID:25895662 sodium arsenite increases expression ISO RGD:1350370 6480464 sodium arsenite results in increased expression of DIAPH3 mRNA CTD PMID:29301061 sunitinib decreases expression ISO RGD:1350370 6480464 Sunitinib results in decreased expression of DIAPH3 mRNA CTD PMID:31533062 tamoxifen affects expression ISO RGD:1314906 6480464 Tamoxifen affects the expression of DIAPH3 mRNA CTD PMID:17555576 testosterone multiple interactions ISO RGD:1350370 6480464 [Testosterone co-treated with Calcitriol] results in decreased expression of DIAPH3 mRNA CTD PMID:21592394 testosterone decreases expression ISO RGD:1350370 6480464 Testosterone results in decreased expression of DIAPH3 mRNA CTD PMID:21592394 tetrachloromethane increases expression ISO RGD:1314906 6480464 Carbon Tetrachloride results in increased expression of DIAPH3 mRNA CTD PMID:17484886 thapsigargin increases expression ISO RGD:1314906 6480464 Thapsigargin results in increased expression of DIAPH3 protein CTD PMID:24648495 thioacetamide increases expression EXP 6480464 Thioacetamide results in increased expression of DIAPH3 mRNA CTD PMID:23411599 titanium dioxide increases expression EXP 6480464 titanium dioxide results in increased expression of DIAPH3 mRNA CTD PMID:30012374 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of DIAPH3 mRNA CTD PMID:25729387 topotecan decreases expression EXP 6480464 Topotecan results in decreased expression of DIAPH3 mRNA CTD PMID:25729387 trimellitic anhydride increases expression ISO RGD:1314906 6480464 trimellitic anhydride results in increased expression of DIAPH3 mRNA CTD PMID:19042947 troglitazone decreases expression ISO RGD:1350370 6480464 troglitazone results in decreased expression of DIAPH3 mRNA CTD PMID:19140230 urethane increases expression ISO RGD:1350370 6480464 Urethane results in increased expression of DIAPH3 mRNA CTD PMID:28818685 valproic acid decreases methylation ISO RGD:1350370 6480464 Valproic Acid results in decreased methylation of DIAPH3 gene CTD PMID:29154799 valproic acid affects expression ISO RGD:1350370 6480464 Valproic Acid affects the expression of DIAPH3 mRNA CTD PMID:25979313 zoledronic acid decreases expression ISO RGD:1350370 6480464 zoledronic acid results in decreased expression of DIAPH3 mRNA CTD PMID:24714768
Biological Process actin cytoskeleton organization ISO RGD:1314906 1624291 (MGI:MGI:6201827, PMID:23558171) RGD MGI:MGI:6201827 , PMID:23558171 actin cytoskeleton organization IEA InterPro:IPR027654 1600115 GO_REF:0000002 InterPro GO_REF:0000002 actin cytoskeleton organization ISS UniProtKB:Q9Z207 1600115 GO_REF:0000024 UniProt GO_REF:0000024 actin filament polymerization ISO RGD:1314906 1624291 (MGI:MGI:6201827, PMID:23558171) RGD MGI:MGI:6201827 , PMID:23558171 actin filament polymerization ISS UniProtKB:Q9Z207 1600115 GO_REF:0000024 UniProt GO_REF:0000024 actin filament polymerization IEA UniProtKB:Q9Z207 , ensembl:ENSMUSP000001294201600115 GO_REF:0000107 Ensembl GO_REF:0000107 cytoskeleton organization ISO RGD:1314906 1624291 (MGI:MGI:6201827, PMID:23558171) RGD MGI:MGI:6201827 , PMID:23558171 cytoskeleton organization ISS UniProtKB:Q9Z207 1600115 GO_REF:0000024 UniProt GO_REF:0000024 spermatogenesis IEP 2314388 RGD Cellular Component cytoplasm IDA 2314388 RGD cytoplasm IEA UniProtKB:Q9Z207 , ensembl:ENSMUSP000001294201600115 GO_REF:0000107 Ensembl GO_REF:0000107 cytoplasm ISO RGD:1314906 1624291 (MGI:MGI:3842878 more ... RGD MGI:MGI:3842878 more ... nucleus IDA 2314388 RGD nucleus IEA UniProtKB:Q9Z207 , ensembl:ENSMUSP000001294201600115 GO_REF:0000107 Ensembl GO_REF:0000107 nucleus ISO RGD:1314906 1624291 (MGI:MGI:3842878 more ... RGD MGI:MGI:3842878 more ... Molecular Function actin binding IEA InterPro:IPR010472 , InterPro:IPR010473 1600115 GO_REF:0000002 InterPro GO_REF:0000002 molecular_function ND 1598407 11/2009: no relevant rat data RGD protein binding ISO RGD:1314906 1624291 UniProtKB:Q8CBW3 (MGI:MGI:3771761 , PMID:18044991) RGD MGI:MGI:3771761 , PMID:18044991 Rho GTPase binding IEA InterPro:IPR010473 , InterPro:IPR027654 1600115 GO_REF:0000002 InterPro GO_REF:0000002 Rho GTPase binding IEA InterPro:IPR027654 1600115 GO_REF:0000002 InterPro GO_REF:0000002
Gene-Chemical Interaction Annotations
