Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Arsb (arylsulfatase B) Rattus norvegicus
Symbol: Arsb
Name: arylsulfatase B
Description: Exhibits sulfuric ester hydrolase activity. Involved in several processes, including nervous system development; response to estrogen; and response to methylmercury. Localizes to several cellular components, including the Golgi apparatus; lysosome; and rough endoplasmic reticulum. Used to study mucopolysaccharidosis VI. Human ortholog(s) of this gene implicated in mucopolysaccharidosis VI. Orthologous to human ARSB (arylsulfatase B); PARTICIPATES IN glycosaminoglycan degradation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Arylsulfatase B (MPS VI); ASB; G4S; N-acetylgalactosamine-4-sulfatase
Homo sapiens (human) : ARSB (arylsulfatase B)  HGNC  Alliance
Mus musculus (house mouse) : Arsb (arylsulfatase B)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Arsb (arylsulfatase B)
Pan paniscus (bonobo/pygmy chimpanzee) : ARSB (arylsulfatase B)
Canis lupus familiaris (dog) : ARSB (arylsulfatase B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Arsb (arylsulfatase B)
Sus scrofa (pig) : ARSB (arylsulfatase B)
more info ...
Allele / Splice: ArsbMPR  
Genetic Models: WIAR.MPR-Arsbabd/Ncchd MPR/Iar
Is Marker For: Strains:   MPR/Iar   WIAR.MPR-Arsbabd/Ncchd  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0223,385,154 - 23,543,028 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl223,385,183 - 23,544,963 (+)Ensembl
Rnor_5.0242,559,079 - 42,717,753 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4224,067,560 - 24,223,821 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1223,988,194 - 24,144,190 (+)NCBI
Celera221,077,645 - 21,235,680 (+)NCBICelera
Cytogenetic Map2q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
Genetic Models
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Arsb
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2158
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.