ARSB (arylsulfatase B) - Rat Genome Database

Name: ARSB
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: ARSB (arylsulfatase B) Pan paniscus

Analyze

Symbol:

ARSB

Name:

arylsulfatase B

RGD ID:

11929262

Description:

ENCODES a protein that exhibits arylsulfatase activity (ortholog); N-acetylgalactosamine-6-sulfatase activity (ortholog); sulfuric ester hydrolase activity (ortholog); INVOLVED IN anterior head development (ortholog); autophagy (ortholog); dermatan sulfate catabolic process (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); genetic disease (ortholog); Hermansky-Pudlak syndrome 2 (ortholog); FOUND IN cell surface (ortholog); lysosome (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

RGD Orthologs

Human

Mouse

Rat

Chinchilla

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ARSB (arylsulfatase B)	NCBI	Ortholog
Mus musculus (house mouse):	Arsb (arylsulfatase B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Arsb (arylsulfatase B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Arsb (arylsulfatase B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ARSB (arylsulfatase B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Arsb (arylsulfatase B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ARSB (arylsulfatase B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ARSB (arylsulfatase B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Arsb (arylsulfatase B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	5	34,473,597 - 34,682,003 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	36,325,581 - 36,534,371 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	36,804,874 - 37,023,746 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	36,804,874 - 37,023,739 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autism spectrum disorder (ISO)

genetic disease (ISO)

Hermansky-Pudlak syndrome 2 (ISO)

metachromatic leukodystrophy (ISO)

mucopolysaccharidosis VI (ISO)

Neurodevelopmental Disorders (ISO)

schizophrenia (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

anterior head development (ISO)

autophagy (ISO)

colon epithelial cell migration (IEA)

dermatan sulfate catabolic process (ISO)

positive regulation of neuron projection development (ISO)

regulation of epithelial cell migration (IEA)

response to estrogen (ISO)

response to methylmercury (ISO)

response to nutrient (ISO)

response to pH (ISO)

Cellular Component

cell surface (ISO)

cellular anatomical entity (IEA)

lysosome (ISO)

Molecular Function

arylsulfatase activity (ISO)

hydrolase activity (IEA)

N-acetylgalactosamine-4-sulfatase activity (IEA)

N-acetylgalactosamine-6-sulfatase activity (ISO)

sulfuric ester hydrolase activity (IEA,ISO)

References

Genomics

Comparative Map Data

ARSB
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	5	34,473,597 - 34,682,003 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	36,325,581 - 36,534,371 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	36,804,874 - 37,023,746 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	36,804,874 - 37,023,739 (+)	Ensembl	panpan1.1		panPan2

ARSB
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	78,777,209 - 78,985,958 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	5	78,777,209 - 78,986,087 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	78,073,032 - 78,281,781 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	78,108,788 - 78,318,113 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	5	78,147,295 - 78,317,522	NCBI
Celera	5	73,966,272 - 74,175,272 (-)	NCBI		Celera
Cytogenetic Map	5	q14.1	NCBI
HuRef	5	73,279,833 - 73,488,328 (-)	NCBI		HuRef
CHM1_1	5	77,506,051 - 77,714,858 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	5	79,258,792 - 79,467,648 (-)	NCBI		T2T-CHM13v2.0

Arsb
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	93,908,187 - 94,079,524 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	13	93,908,138 - 94,079,524 (+)	Ensembl		GRCm39 Ensembl
GRCm38	13	93,771,679 - 93,943,016 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	93,771,630 - 93,943,016 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	13	94,541,634 - 94,712,971 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	13	94,872,512 - 95,041,668 (+)	NCBI		MGSCv36	mm8
Celera	13	97,379,077 - 97,564,231 (+)	NCBI		Celera
Cytogenetic Map	13	C3	NCBI
cM Map	13	47.88	NCBI

Arsb
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	2	25,002,210 - 25,162,675 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	25,002,346 - 25,162,671 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	32,029,775 - 32,188,228 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	2	30,130,038 - 30,288,496 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	2	24,954,935 - 25,113,379 (+)	NCBI	Rnor_WKY
Rnor_6.0	2	23,385,154 - 23,543,028 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	23,385,183 - 23,544,963 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	42,559,079 - 42,717,753 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	24,067,560 - 24,223,821 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	23,988,194 - 24,144,190 (+)	NCBI
Celera	2	21,077,645 - 21,235,680 (+)	NCBI		Celera
Cytogenetic Map	2	q12	NCBI

Arsb
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955425	22,119,930 - 22,279,006 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955425	22,120,507 - 22,281,221 (+)	NCBI	ChiLan1.0	ChiLan1.0

ARSB
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	3	27,870,111 - 28,034,906 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	3	27,870,151 - 28,034,906 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	3	29,107,602 - 29,273,552 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	3	27,790,052 - 27,973,468 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	3	27,790,052 - 27,958,957 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	3	27,726,564 - 27,892,579 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	3	27,705,072 - 27,870,890 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	3	28,031,550 - 28,197,915 (+)	NCBI		UU_Cfam_GSD_1.0

Arsb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	184,032,193 - 184,203,920 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936549	6,653,978 - 6,826,349 (-)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936549	6,654,259 - 6,827,647 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ARSB
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	87,614,963 - 87,778,447 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	87,614,938 - 87,779,553 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	89,559,337 - 89,591,727 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ARSB
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	4	73,016,497 - 73,203,570 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	4	73,015,980 - 73,202,439 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666049	21,862,979 - 22,049,954 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Arsb
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624869	3,289,430 - 3,476,437 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624869	3,226,633 - 3,476,071 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_034959909	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034959910	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034959911	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSPPAT00000058300 ⟹ ENSPPAP00000035412

RefSeq Status:

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	5	36,804,874 - 37,023,739 (+)	Ensembl

RefSeq Acc Id:

ENSPPAT00000058302 ⟹ ENSPPAP00000035414

RefSeq Status:

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	5	36,815,444 - 36,985,550 (+)	Ensembl

RefSeq Acc Id:

XM_034959909 ⟹ XP_034815800

RefSeq Status:

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1	5	34,473,597 - 34,682,003 (+)	NCBI
Mhudiblu_PPA_v0	5	36,325,581 - 36,534,371 (+)	NCBI

RefSeq Acc Id:

XM_034959910 ⟹ XP_034815801

RefSeq Status:

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1	5	34,473,597 - 34,644,051 (+)	NCBI
Mhudiblu_PPA_v0	5	36,325,581 - 36,496,499 (+)	NCBI

RefSeq Acc Id:

XM_034959911 ⟹ XP_034815802

RefSeq Status:

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1	5	34,473,597 - 34,622,545 (+)	NCBI
Mhudiblu_PPA_v0	5	36,325,581 - 36,474,900 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_034815800	(Get FASTA)	NCBI Sequence Viewer
	XP_034815801	(Get FASTA)	NCBI Sequence Viewer
	XP_034815802	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	XP_034815800 ⟸ XM_034959909
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_034815801 ⟸ XM_034959910
- Peptide Label:	isoform X2
- UniProtKB:	K7CKP9 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_034815802 ⟸ XM_034959911
- Peptide Label:	isoform X3

RefSeq Acc Id:

ENSPPAP00000035412 ⟸ ENSPPAT00000058300

RefSeq Acc Id:

ENSPPAP00000035414 ⟸ ENSPPAT00000058302

Protein Domains

Sulfatase N-terminal

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000040516	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSPPAP00000035412.1	UniProtKB/TrEMBL
	ENSPPAP00000035414.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000058300.1	UniProtKB/TrEMBL
	ENSPPAT00000058302.1	UniProtKB/TrEMBL
Gene3D-CATH	3.30.1120.10	UniProtKB/TrEMBL
	3.40.720.10	UniProtKB/TrEMBL
InterPro	Alkaline_phosphatase_core_sf	UniProtKB/TrEMBL
	ARSB	UniProtKB/TrEMBL
	Sulfatase_CS	UniProtKB/TrEMBL
	Sulfatase_N	UniProtKB/TrEMBL
NCBI Gene	ARSB	ENTREZGENE
PANTHER	ARYLSULFATASE	UniProtKB/TrEMBL
	ARYLSULFATASE B	UniProtKB/TrEMBL
Pfam	Sulfatase	UniProtKB/TrEMBL
PROSITE	SULFATASE_1	UniProtKB/TrEMBL
	SULFATASE_2	UniProtKB/TrEMBL
Superfamily-SCOP	SSF53649	UniProtKB/TrEMBL
UniProt	A0A2R9C0H9_PANPA	UniProtKB/TrEMBL
	A0A2R9CAP3_PANPA	UniProtKB/TrEMBL
	K7CKP9	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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