Bp389 QTL Report (Rattus norvegicus) - Rat Genome Database

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QTL: Bp389 (Blood pressure QTL 389) Rattus norvegicus

Symbol: Bp389
Name: Blood pressure QTL 389
RGD ID: 10755499
Previously known as: BP-pm3
Trait: arterial blood pressure trait   (VT:2000000)    
Measurement Type: diastolic blood pressure   (CMO:0000005)    
LOD Score: 2.61
P Value: Not Available
Variance: 9.0
Inheritance Type: recessive
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0216,679,272 - 245,624,402RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0216,543,933 - 264,155,674RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4217,573,311 - 237,865,985RGD_MAPPER_PIPELINERGSC3.4
Cross Type: intercross
Strains Crossed: SR/JrHsd SS/JrHsd 



Disease Annotations     Click to see Annotation Detail View
hypertension  (IAGP)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

Experimental Condition

Measurement Method

Vertebrate Trait

Rat Strain
SR/JrHsd  (IEA)
SS/JrHsd  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Differential genetic basis for pre-menopausal and post-menopausal salt-sensitive hypertension. Herrera VL, etal., PLoS One. 2012;7(8):e43160. doi: 10.1371/journal.pone.0043160. Epub 2012 Aug 17.
Related QTLs

Related QTL Description Reference
Bp202 maps to same region RGD:10755344
Bp239 maps to same region RGD:10755344
Bp175 maps to same region RGD:10755344


Region

Markers in Region
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolExpected SizeChrStartStopSpeciesMatch
Position Markers

Flank 1: (rs105812402)
Rat AssemblyChrPosition (strand)Source
Rnor_6.0216,679,272 - 16,679,272RGD
Rnor_5.0216,543,933 - 16,543,933RGD
RGSC_v3.4217,573,311 - 17,573,311RGD
Flank 2: (rs64512962)
Rat AssemblyChrPosition (strand)Source
Rnor_6.02245,624,402 - 245,624,402RGD
Rnor_5.02264,155,674 - 264,155,674RGD
RGSC_v3.42237,865,985 - 237,865,985RGD


Additional Information

RGD Curation Notes
Note Type Note Reference
qtl_general region spans 218-248 Mbp 10755344
qtl_general number of animals used: 130 F2 females 10755344
qtl_general software used: Map Manager QTXb19 10755344
qtl_general to confirm post-menopausal status, vaginal smears were done to determine the estrous cycle stage 10755344
qtl_general measurement method: 8% NaCl diet was started at 14 weeks of age and given for 4 weeks; non-stressed blood pressure measurements were taken by intra-aortic abdominal radiotelemetric implants over 10 seconds every 5 minutes for 24 hours 10755344