Arsb (arylsulfatase B) - Rat Genome Database

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Gene: Arsb (arylsulfatase B) Mus musculus
Analyze
Symbol: Arsb
Name: arylsulfatase B
RGD ID: 10193
MGI Page MGI
Description: Enables N-acetylgalactosamine-6-sulfatase activity and arylsulfatase activity. Involved in dermatan sulfate catabolic process. Acts upstream of or within anterior head development. Located in cell surface. Is active in lysosome. Is expressed in skeleton. Used to study mucopolysaccharidosis VI. Human ortholog(s) of this gene implicated in mucopolysaccharidosis VI. Orthologous to human ARSB (arylsulfatase B).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1110007C02Rik; A; AI480648; arylsulfatase B complex; arylsulfatase B regulation; arylsulfatase B structural; arylsulfatase B temporal regulation; As; As-; As-1; As-1r; As-1s; As-1t; As1; As1-r; As1-s; As1-t; ASB; Asr-1; Ast; Ast-1; G4S; N-acetylgalactosamine-4-sulfatase
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391393,908,187 - 94,079,524 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1393,908,138 - 94,079,524 (+)EnsemblGRCm39 Ensembl
GRCm381393,771,679 - 93,943,016 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1393,771,630 - 93,943,016 (+)EnsemblGRCm38mm10GRCm38
MGSCv371394,541,634 - 94,712,971 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361394,872,512 - 95,041,668 (+)NCBIMGSCv36mm8
Celera1397,379,077 - 97,564,231 (+)NCBICelera
Cytogenetic Map13C3NCBI
cM Map1347.88NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
4,4'-diaminodiphenylmethane  (ISO)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
buspirone  (ISO)
C60 fullerene  (ISO)
chlordecone  (EXP)
chondroitin sulfate  (ISO)
cisplatin  (ISO)
DDT  (ISO)
dextran sulfate  (EXP)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
dioxygen  (EXP)
doxorubicin  (ISO)
ethanol  (EXP)
ethyl methanesulfonate  (ISO)
flutamide  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
gentamycin  (ISO)
hydrogen peroxide  (ISO)
irinotecan  (ISO)
methapyrilene  (ISO)
methimazole  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
monosodium L-glutamate  (EXP)
N,N-diethyl-m-toluamide  (ISO)
N-nitrosodiethylamine  (EXP)
nickel atom  (ISO)
O-methyleugenol  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
pentachlorophenol  (EXP)
perfluorooctanoic acid  (ISO)
permethrin  (ISO)
piperonyl butoxide  (EXP)
pirinixic acid  (ISO)
poly(I:C)  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (ISO)
tetrachloromethane  (EXP)
thapsigargin  (ISO)
theophylline  (ISO)
triphenyl phosphate  (ISO)
troglitazone  (EXP)
valproic acid  (ISO)
vinclozolin  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cell surface  (IDA,ISO)
lysosome  (IDA)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal articular cartilage morphology  (IAGP)
abnormal blood cell morphology/development  (IAGP)
abnormal cartilage morphology  (IAGP)
abnormal cell morphology  (IAGP)
abnormal cornea morphology  (IAGP)
abnormal corneal epithelium morphology  (IAGP)
abnormal digit morphology  (IEA)
abnormal gait  (IEA)
abnormal heart valve morphology  (IAGP)
abnormal lysosome physiology  (IEA)
abnormal pelvic girdle bone morphology  (IAGP)
abnormal rib morphology  (IAGP)
abnormal tracheal cartilage morphology  (IAGP)
broad head  (IAGP)
decreased body size  (IEA)
decreased body weight  (IAGP)
decreased cardiac muscle contractility  (IAGP)
decreased cardiac output  (IAGP)
decreased corneal epithelium thickness  (IAGP)
decreased length of long bones  (IAGP)
decreased litter size  (IEA)
decreased percent body fat/body weight  (IEA)
decreased systemic arterial blood pressure  (IAGP)
disorganized corneal epithelium  (IAGP)
disorganized long bone epiphyseal plate  (IAGP)
heart valve hyperplasia  (IAGP)
increased autopod size  (IAGP)
increased bone mineral density  (IEA)
increased cranium width  (IAGP)
increased long bone epiphyseal plate size  (IAGP)
increased or absent threshold for auditory brainstem response  (IEA)
increased urine glycosaminoglycan level  (IAGP)
mitral valve regurgitation  (IAGP)
ocular hypertelorism  (IEA)
peripheral nervous system degeneration  (IEA)
reduced fertility  (IEA)
short femur  (IAGP)
short limbs  (IAGP)
short maxilla  (IAGP)
short snout  (IAGP)
short tibia  (IAGP)
skeletal muscle degeneration  (IEA)
thick mitral valve  (IAGP)
thick tail  (IEA)
References

References - curated
# Reference Title Reference Citation
1. Anti-TNF-alpha therapy enhances the effects of enzyme replacement therapy in rats with mucopolysaccharidosis type VI. Eliyahu E, etal., PLoS One. 2011;6(8):e22447. doi: 10.1371/journal.pone.0022447. Epub 2011 Aug 22.
2. Mucopolysaccharidosis type VI: identification of three mutations in the arylsulfatase B gene of patients with the severe and mild phenotypes provides molecular evidence for genetic heterogeneity. Jin WD, etal., Am J Hum Genet. 1992 Apr;50(4):795-800.
3. Mucopolysaccharidosis type VI in rats: isolation of cDNAs encoding arylsulfatase B, chromosomal localization of the gene, and identification of the mutation. Kunieda T, etal., Genomics 1995 Oct 10;29(3):582-7.
4. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
5. MGDs mouse GO annotations MGD data from the GO Consortium
6. MGD IEA MGD IEA
7. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
8. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
9. Mouse MP Annotation Import Pipeline RGD automated import pipeline
10. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:1016219   PMID:1348494   PMID:1352323   PMID:1421760   PMID:1572648   PMID:1685136   PMID:1686016   PMID:2307475   PMID:2574500   PMID:4031460   PMID:4084217   PMID:7069188  
PMID:7247931   PMID:7391540   PMID:7470017   PMID:8094988   PMID:8169823   PMID:8482578   PMID:8661713   PMID:8710849   PMID:8828042   PMID:8889548   PMID:9266612   PMID:9337408  
PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12477932   PMID:12904606   PMID:14681479   PMID:15782199   PMID:16141072   PMID:16141073   PMID:16174644  
PMID:18285341   PMID:19536613   PMID:20503373   PMID:21267068   PMID:24240681   PMID:24778176   PMID:25511584   PMID:26234751   PMID:27078017   PMID:27605497   PMID:27658524   PMID:28124772  
PMID:29773673   PMID:30075049   PMID:30333137   PMID:30550785   PMID:31943020   PMID:32325033   PMID:32413051   PMID:32595831   PMID:33905568   PMID:36213247   PMID:37751300  


Genomics

Comparative Map Data
Arsb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391393,908,187 - 94,079,524 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1393,908,138 - 94,079,524 (+)EnsemblGRCm39 Ensembl
GRCm381393,771,679 - 93,943,016 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1393,771,630 - 93,943,016 (+)EnsemblGRCm38mm10GRCm38
MGSCv371394,541,634 - 94,712,971 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361394,872,512 - 95,041,668 (+)NCBIMGSCv36mm8
Celera1397,379,077 - 97,564,231 (+)NCBICelera
Cytogenetic Map13C3NCBI
cM Map1347.88NCBI
ARSB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38578,777,209 - 78,985,958 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl578,777,209 - 78,986,087 (-)EnsemblGRCh38hg38GRCh38
GRCh37578,073,032 - 78,281,781 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36578,108,788 - 78,318,113 (-)NCBINCBI36Build 36hg18NCBI36
Build 34578,147,295 - 78,317,522NCBI
Celera573,966,272 - 74,175,272 (-)NCBICelera
Cytogenetic Map5q14.1NCBI
HuRef573,279,833 - 73,488,328 (-)NCBIHuRef
CHM1_1577,506,051 - 77,714,858 (-)NCBICHM1_1
T2T-CHM13v2.0579,258,792 - 79,467,648 (-)NCBIT2T-CHM13v2.0
Arsb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8226,736,395 - 26,895,682 (+)NCBIGRCr8
mRatBN7.2225,002,210 - 25,162,675 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl225,002,346 - 25,162,671 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx232,029,775 - 32,188,228 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0230,130,038 - 30,288,496 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0224,954,935 - 25,113,379 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0223,385,154 - 23,543,028 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl223,385,183 - 23,544,963 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0242,559,079 - 42,717,753 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4224,067,560 - 24,223,821 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1223,988,194 - 24,144,190 (+)NCBI
Celera221,077,645 - 21,235,680 (+)NCBICelera
Cytogenetic Map2q12NCBI
Arsb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542522,119,930 - 22,279,006 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542522,120,507 - 22,281,221 (+)NCBIChiLan1.0ChiLan1.0
ARSB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2436,319,804 - 36,528,385 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1534,473,431 - 34,682,012 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0536,325,581 - 36,534,371 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1536,804,874 - 37,023,746 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl536,804,874 - 37,023,739 (+)Ensemblpanpan1.1panPan2
ARSB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1327,870,111 - 28,034,906 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl327,870,151 - 28,034,906 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha329,107,602 - 29,273,552 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0327,790,052 - 27,973,468 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl327,790,052 - 27,958,957 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1327,726,564 - 27,892,579 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0327,705,072 - 27,870,890 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0328,031,550 - 28,197,915 (+)NCBIUU_Cfam_GSD_1.0
Arsb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213184,032,193 - 184,203,920 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365496,653,978 - 6,826,349 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365496,654,259 - 6,827,647 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARSB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl287,614,963 - 87,778,447 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1287,614,938 - 87,779,553 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2289,559,337 - 89,591,727 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ARSB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1473,016,497 - 73,203,570 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl473,015,980 - 73,202,439 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604921,862,979 - 22,049,954 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arsb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248693,289,430 - 3,476,437 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248693,226,633 - 3,476,071 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Arsb
6191 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:687
Count of miRNA genes:477
Interacting mature miRNAs:538
Transcripts:ENSMUST00000091403
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142147Mvwf4_mmodifier of von Willebrand factor 4 (mouse)Not determined20477612112898424Mouse
10412235Scgq5_mspontaneous crescentic glomerulonephritis QTL 5 (mouse)Not determined133606090896239162Mouse
4142314Tailaq3_mtail length adjusted QTL 3 (mouse)Not determined55720354112431103Mouse
4140959W10q17_mweight 10 weeks QTL 17 (mouse)Not determined55720354112431103Mouse
4141992W6q16_mweight 6 weeks QTL 16 (mouse)Not determined55720354112431103Mouse
4142241Tailq3_mtail length QTL 3 (mouse)Not determined55720354112431103Mouse
10402414Sgp5_mserum gp70 production 5 (mouse)Not determined1356470456105422186Mouse
1357553Cia28_mcollagen induced arthritis 28 (mouse)Not determined135662924996239162Mouse
1300941Skl6_mskeletal size (tail length) 6 (mouse)Not determined136425082198250945Mouse
1301949Skull20_mskull morphology 20 (mouse)Not determined136425082198250945Mouse
1301445Listr2_mlisteriosis resistance 2 (mouse)Not determined1366744601100744746Mouse
1301593Heal8_mwound healing/regeneration 8 (mouse)Not determined1368053999102054119Mouse
14696726Kidrq3_mkidney weight, right QTL 3 (mouse)1368217066102217066Mouse
14747007Mancz11_mmandible centroid size 11 (mouse)1370111284104111284Mouse
4141266Mol3_mmodifier of LPS-response 3 (mouse)Not determined76132600112431103Mouse
1301610Dps1_mdelta power in slow-wave sleep 1 (mouse)Not determined137719586295730894Mouse
12880414V125Dq10_mvitamin D active form serum level QTL 10 (mouse)1378036508112036508Mouse
12880402Emlq1_memotional learning QTL 1 (mouse)137810885896866553Mouse
12879495Fexq1_mfear expression QTL 1 (mouse)137826885895836553Mouse
10043997Bw40_mbody weight QTL 40 (mouse)Not determined1479239045113239162Mouse
10045623Heal18_mwound healing regeneration 18 (mouse)Not determined1379239045113239162Mouse
1558741Ses10_msalmonella enteritidis susceptibility 10 (mouse)Not determined1382739968116740106Mouse
4142465Pbwg17_mpostnatal body weight growth 17 (mouse)Not determined1383876060117876256Mouse
14700691Cisaq1_mcoxsackieviral infection serum ALT QTL 1 (mouse)1386148119120461536Mouse
4140995Fbtq6_mfemoral bone trait QTL 6 (mouse)Not determined1386341617120341758Mouse
4141728Egaq4_mearly growth adjusted QTL 4 (mouse)Not determined87901985112431103Mouse
1300939Hrtfm6_mheart failure modifier 6 (mouse)Not determined1391383692120883175Mouse
1300876Tanidd2_mtally ho associated non-insulin dependednt diabetes mellitus 2 (mouse)Not determined1391965303120883175Mouse
1301142Heal2_mwound healing/regeneration 2 (mouse)Not determined1393875267120883175Mouse

Markers in Region
AI480648  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381393,942,617 - 93,942,700UniSTSGRCm38
MGSCv371394,712,572 - 94,712,655UniSTSGRCm37
Celera1397,563,832 - 97,563,915UniSTS
Cytogenetic Map13C3-D1UniSTS
Whitehead/MRC_RH13808.15UniSTS
UniSTS:237081  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381393,942,618 - 93,942,971UniSTSGRCm38
MGSCv371394,712,573 - 94,712,926UniSTSGRCm37
Celera1397,563,833 - 97,564,186UniSTS
Cytogenetic Map13C3-D1UniSTS
Arsb  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13C3-D1UniSTS
cM Map1347.88UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_009712 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC131739 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC136976 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AEKQ02122624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK003524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK037155 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK083309 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK140163 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK154098 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK158312 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK189106 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK190270 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK191477 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK195452 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK195674 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK198200 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205135 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK211718 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK212274 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK212990 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC055876 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC150661 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BN000746 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466567 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M82877 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X92096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000091403   ⟹   ENSMUSP00000088964
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1393,908,138 - 94,079,524 (+)Ensembl
GRCm38.p6 Ensembl1393,771,630 - 93,943,016 (+)Ensembl
RefSeq Acc Id: ENSMUST00000220652
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1393,908,204 - 94,010,317 (+)Ensembl
GRCm38.p6 Ensembl1393,771,696 - 93,873,809 (+)Ensembl
RefSeq Acc Id: NM_009712   ⟹   NP_033842
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391393,908,187 - 94,079,524 (+)NCBI
GRCm381393,771,679 - 93,943,016 (+)NCBI
MGSCv371394,541,634 - 94,712,971 (+)RGD
Celera1397,379,077 - 97,564,231 (+)RGD
cM Map13 ENTREZGENE
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_033842   ⟸   NM_009712
- Peptide Label: precursor
- UniProtKB: Q8C404 (UniProtKB/Swiss-Prot),   Q3U4Q6 (UniProtKB/Swiss-Prot),   Q3TYV7 (UniProtKB/Swiss-Prot),   Q32KJ1 (UniProtKB/Swiss-Prot),   P50429 (UniProtKB/Swiss-Prot),   A0A0R4J138 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000088964   ⟸   ENSMUST00000091403
Protein Domains
Sulfatase N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P50429-F1-model_v2 AlphaFold P50429 1-534 view protein structure

Promoters
RGD ID:8681020
Promoter ID:EPDNEW_M18541
Type:initiation region
Name:Arsb_1
Description:Mus musculus arylsulfatase B , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381393,771,724 - 93,771,784EPDNEW
RGD ID:6823653
Promoter ID:MM_KWN:14926
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:UC007RLN.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361394,541,466 - 94,542,292 (-)MPROMDB
RGD ID:6823707
Promoter ID:MM_KWN:14927
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour
Transcripts:ENSMUST00000109482,   NM_009712
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361394,541,601 - 94,542,101 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:88075 AgrOrtholog
Ensembl Genes ENSMUSG00000042082 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSG00000042093
Ensembl Transcript ENSMUST00000091403 ENTREZGENE
  ENSMUST00000091403.6 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1120.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.720.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Alkaline_phosphatase_core_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ARSB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sulfatase_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sulfatase_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:11881 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:88075 ENTREZGENE
NCBI Gene 11881 ENTREZGENE
PANTHER ARYLSULFATASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ARYLSULFATASE B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Sulfatase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Arsb PhenoGen
PROSITE SULFATASE_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SULFATASE_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF53649 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0R4J138 ENTREZGENE, UniProtKB/TrEMBL
  ARSB_MOUSE UniProtKB/Swiss-Prot
  B2RWQ7_MOUSE UniProtKB/TrEMBL
  P50429 ENTREZGENE
  Q32KJ1 ENTREZGENE
  Q3TYV7 ENTREZGENE
  Q3U4Q6 ENTREZGENE
  Q8C404 ENTREZGENE
  Q9D1I3_MOUSE UniProtKB/TrEMBL
UniProt Secondary Q32KJ1 UniProtKB/Swiss-Prot
  Q3TYV7 UniProtKB/Swiss-Prot
  Q3U4Q6 UniProtKB/Swiss-Prot
  Q8C404 UniProtKB/Swiss-Prot