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Gene: Avp (arginine vasopressin) Rattus norvegicus
Symbol: Avp
Name: arginine vasopressin
RGD ID: 2184
Description: Exhibits V1A vasopressin receptor binding activity; V1B vasopressin receptor binding activity; and neuropeptide hormone activity. Involved in several processes, including cellular cation homeostasis; mating; and regulation of secretion. Localizes to dendrite; extracellular space; and secretory granule. Used to study hyperglycemia; portal hypertension; and temporal lobe epilepsy. Biomarker of hypertension; neurohypophyseal diabetes insipidus; type 2 diabetes mellitus; and vascular dementia. Human ortholog(s) of this gene implicated in diabetes insipidus and neurohypophyseal diabetes insipidus. Orthologous to human AVP (arginine vasopressin); PARTICIPATES IN vasopressin signaling pathway; vasopressin signaling pathway via receptor type 1; vasopressin signaling pathway via receptor type 2; INTERACTS WITH (R)-noradrenaline; (S)-colchicine; (S)-nicotine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ADH; antidiuretic hormone; Arginine vasopressin (Diabetes insipidus); arginine vasopressin (Diabetes insipidus) same as Di (conflicting physical mapping); arginine vasopressin (Diabetes insipidus), same as Di (conflicting physical mapping); AVP-NPII; DI; prepropressophysin; preprovasopressin-neurophysin; Vas; vasopressin; vasopressin-neurophysin 2-copeptin; vasopressin-neurophysin prepropeptide; VP
Homo sapiens (human) : AVP (arginine vasopressin)  HGNC  Alliance
Mus musculus (house mouse) : Avp (arginine vasopressin)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : AVP (arginine vasopressin)
Canis lupus familiaris (dog) : AVP (arginine vasopressin)
Sus scrofa (pig) : AVP (arginine vasopressin)
Chlorocebus sabaeus (African green monkey) : AVP (arginine vasopressin)
Heterocephalus glaber (naked mole-rat) : Avp (arginine vasopressin)
more info ...
Allele / Splice: Avpdi  
Genetic Models: BRAT-Avpdi/BluHsd BRAT-Avpdi/BluHsdRrrc
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.03123,117,482 - 123,119,460 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3123,117,492 - 123,119,460 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03129,615,610 - 129,627,147 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43118,205,007 - 118,206,985 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13118,110,580 - 118,112,558 (-)NCBI
Celera3116,604,316 - 116,606,294 (-)NCBICelera
Cytogenetic Map3q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Avp
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2184
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-08-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.