Gene: Avp (arginine vasopressin) Mus musculus
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Symbol:
Avp
Name:
arginine vasopressin
Description:
Predicted to have molecular function regulator; protein kinase activity; and vasopressin receptor binding activity. Predicted to be involved in several processes, including cellular cation homeostasis; mating; and negative regulation of apoptotic process. Predicted to localize to the dendrite; extracellular space; and secretory granule. Used to study neurohypophyseal diabetes insipidus. Human ortholog(s) of this gene implicated in diabetes insipidus and neurohypophyseal diabetes insipidus. Is expressed in several structures, including alimentary system; cardiovascular system; integumental system; nervous system; and sensory organ. Orthologous to human AVP (arginine vasopressin).
Type:
protein-coding
RefSeq Status:
REVIEWED
Also known as:
AVP-NPII; pre-pro-arginine-vasopressin-neurophysin II; prepro-AVP-NP II; vasopressin-neurophysin 2-copeptin; Vp; Vsp
Orthologs:
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
AVP (arginine vasopressin) HGNC
EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):
Avp (arginine vasopressin) HGNC
Treefam, EggNOG, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, Panther, PhylomeDB, OrthoDB, Ensembl
Canis lupus familiaris (dog):
AVP (arginine vasopressin) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
AVP (arginine vasopressin) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
OXT (oxytocin/neurophysin I prepropeptide) HGNC
OrthoDB
Alliance orthologs 3
Rattus norvegicus (Norway rat):
Avp (arginine vasopressin)
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Homo sapiens (human):
AVP (arginine vasopressin)
Alliance
DIOPT (HGNC, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PhylomeDB, Roundup, TreeFam)
Danio rerio (zebrafish):
avp (arginine vasopressin)
Alliance
DIOPT (Ensembl Compara, OMA, OrthoFinder, PANTHER, PhylomeDB, Roundup, TreeFam, ZFIN)
Caenorhabditis elegans (roundworm):
ntc-1
Alliance
DIOPT (OrthoFinder, PhylomeDB)
Latest Assembly:
GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm38 2 130,580,620 - 130,582,588 (-) NCBI GRCm38 GRCm38 mm10 GRCm38 MGSCv37 2 130,406,413 - 130,408,277 (-) NCBI GRCm37 mm9 NCBIm37 MGSCv36 2 130,272,118 - 130,273,982 (-) NCBI mm8 Celera 2 131,805,101 - 131,806,965 (-) NCBI Celera Cytogenetic Map 2 F1 NCBI cM Map 2 63.24 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Disease Annotations
Imported Annotations - ClinVar
neurohypophyseal diabetes insipidus ISO RGD:68968 8554872 ClinVar Annotator: match by OMIM:125700 ClinVar neurohypophyseal diabetes insipidus ISO RGD:68968 8554872 ClinVar Annotator: match by term: Diabetes insipidus, neurohypophyseal, autosomal recessive ClinVar PMID:10369876 , PMID:15356057 neurohypophyseal diabetes insipidus ISO RGD:68968 8554872 ClinVar Annotator: match by OMIM:125700 ClinVar PMID:15070970 neurohypophyseal diabetes insipidus ISO RGD:68968 8554872 ClinVar Annotator: match by OMIM:125700 ClinVar PMID:8550751 neurohypophyseal diabetes insipidus ISO RGD:68968 8554872 ClinVar Annotator: match by OMIM:125700 ClinVar PMID:9467595 neurohypophyseal diabetes insipidus ISO RGD:68968 8554872 ClinVar Annotator: match by OMIM:125700 ClinVar PMID:10487710 , PMID:9360520 neurohypophyseal diabetes insipidus ISO RGD:68968 8554872 ClinVar Annotator: match by OMIM:125700 ClinVar PMID:11017955 , PMID:11443218 neurohypophyseal diabetes insipidus ISO RGD:68968 8554872 ClinVar Annotator: match by OMIM:125700 ClinVar PMID:1840604 , PMID:6132221 neurohypophyseal diabetes insipidus ISO RGD:68968 8554872 ClinVar Annotator: match by OMIM:125700 ClinVar PMID:7714110 neurohypophyseal diabetes insipidus ISO RGD:68968 8554872 ClinVar Annotator: match by OMIM:125700 ClinVar PMID:8989232 , PMID:9467595 neurohypophyseal diabetes insipidus ISO RGD:68968 8554872 ClinVar Annotator: match by OMIM:125700 ClinVar PMID:9814475 neurohypophyseal diabetes insipidus ISO RGD:68968 8554872 ClinVar Annotator: match by OMIM:125700 ClinVar PMID:8626836 neurohypophyseal diabetes insipidus ISO RGD:68968 8554872 ClinVar Annotator: match by OMIM:125700 ClinVar PMID:1740104 , PMID:8945633 neurohypophyseal diabetes insipidus ISO RGD:68968 8554872 ClinVar Annotator: match by OMIM:125700 ClinVar PMID:14660745 , PMID:7714110 neurohypophyseal diabetes insipidus ISO RGD:68968 8554872 ClinVar Annotator: match by OMIM:125700 ClinVar PMID:9580132 neurohypophyseal diabetes insipidus ISO RGD:68968 8554872 ClinVar Annotator: match by OMIM:125700 ClinVar PMID:10443701 more ... neurohypophyseal diabetes insipidus ISO RGD:68968 8554872 ClinVar Annotator: match by OMIM:125700 ClinVar PMID:14673472 neurohypophyseal diabetes insipidus ISO RGD:68968 8554872 ClinVar Annotator: match by OMIM:125700 ClinVar PMID:12107248 , PMID:15356057 neurohypophyseal diabetes insipidus ISO RGD:68968 8554872 ClinVar Annotator: match by OMIM:125700 ClinVar PMID:11836335 , PMID:8103767
Imported Annotations - CTD
acute kidney failure ISO RGD:68968 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:2139164 amnestic disorder ISO RGD:68968 11554173 CTD Direct Evidence: therapeutic CTD PMID:7562510 Angina Pectoris ISO RGD:68968 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:11128043 , PMID:11791009 autistic disorder ISO RGD:68968 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:8570775 Cardiac Arrhythmias ISO RGD:68968 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:6983645 cardiomyopathy ISO RGD:68968 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:12145768 congestive heart failure ISO RGD:68968 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:18179782 Dehydration ISO RGD:68968 11554173 CTD Direct Evidence: therapeutic CTD PMID:2554359 diabetes insipidus ISO RGD:68968 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:6945054 , PMID:15169711 Drug Overdose ISO RGD:68968 11554173 CTD Direct Evidence: therapeutic CTD PMID:11914425 Dysmenorrhea ISO RGD:68968 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:10440088 Gastrointestinal Hemorrhage ISO RGD:68968 11554173 CTD Direct Evidence: therapeutic CTD PMID:6983645 Hyperalgesia ISO RGD:68968 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:9613798 hypertension ISO RGD:68968 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:1663982 more ... Hyponatremia ISO RGD:68968 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:6920297 Hypotension ISO RGD:68968 11554173 CTD Direct Evidence: therapeutic CTD PMID:2485266 more ... inappropriate ADH syndrome ISO RGD:68968 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:112579 , PMID:6920297 ischemia ISO RGD:68968 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:2139164 , PMID:10440088 lung small cell carcinoma ISO RGD:68968 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:2832203 Memory Disorders ISO RGD:68968 11554173 CTD Direct Evidence: therapeutic CTD PMID:11553362 neurohypophyseal diabetes insipidus ISO RGD:68968 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:7057320 Pain ISO RGD:68968 11554173 CTD Direct Evidence: therapeutic CTD PMID:2271928 , PMID:6094376 Polyuria ISO RGD:68968 11554173 CTD Direct Evidence: therapeutic CTD PMID:11012637 portal hypertension ISO RGD:68968 11554173 CTD Direct Evidence: therapeutic CTD PMID:6696534 psychotic disorder ISO RGD:68968 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:3567260 schizophrenia ISO RGD:68968 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:3567260 Shock ISO RGD:68968 11554173 CTD Direct Evidence: therapeutic CTD PMID:10570779 Shy-Drager Syndrome ISO RGD:68968 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:6850280 withdrawal disorder ISO RGD:68968 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:4040330 Imported Annotations - MGI
neurohypophyseal diabetes insipidus IEA 13592920 OMIM:125700 , OMIM:304900MouseDO Imported Annotations - OMIM
neurohypophyseal diabetes insipidus ISO RGD:68968 7240710 OMIM
(R)-noradrenaline multiple interactions ISO RGD:2184 6480464 [AVP protein co-treated with Norepinephrine] inhibits the reaction [Triiodothyronine inhibits the reaction [EGF protein results in decreased expression of UCP1 mRNA]] more ... CTD PMID:11742803 (S)-colchicine decreases transport ISO RGD:2184 6480464 Colchicine results in decreased transport of AVP protein CTD PMID:2453250 (S)-nicotine increases secretion ISO RGD:2184 6480464 Nicotine results in increased secretion of AVP protein alternative form CTD PMID:3681699 (S)-nicotine decreases expression ISO RGD:2184 6480464 Nicotine results in decreased expression of AVP mRNA CTD PMID:28555334 (S)-nicotine decreases expression EXP 6480464 Nicotine results in decreased expression of AVP mRNA CTD PMID:17456735 1-(propan-2-ylamino)-3-(2-prop-2-enoxyphenoxy)-2-propanol decreases expression ISO RGD:68968 6480464 Oxprenolol results in decreased expression of AVP protein CTD PMID:6367368 2,2',4,4'-Tetrabromodiphenyl ether affects secretion ISO RGD:2184 6480464 2 more ... CTD PMID:17434953 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:2184 6480464 Tetrachlorodibenzodioxin results in increased expression of AVP mRNA CTD PMID:18824019 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of AVP mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 Tetrachlorodibenzodioxin affects the reaction [AHR protein binds to AVP promoter] CTD PMID:19654925 2,6-dinitrotoluene affects expression ISO RGD:2184 6480464 2, 6-dinitrotoluene affects the expression of AVP mRNA CTD PMID:21346803 3',5'-cyclic AMP multiple interactions ISO RGD:68968 6480464 [AVP protein binds to and results in increased activity of AVPR2 protein mutant form] which results in increased abundance of Cyclic AMP, [AVP protein binds to and results in increased activity of AVPR2 protein] which results in increased abundance of Cyclic AMP CTD PMID:20683494 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine increases expression ISO RGD:2184 6480464 Puromycin Aminonucleoside results in increased expression of AVP protein CTD PMID:7810534 3,3',5-triiodo-L-thyronine multiple interactions ISO RGD:2184 6480464 [AVP protein co-treated with Norepinephrine] inhibits the reaction [Triiodothyronine inhibits the reaction [EGF protein results in decreased expression of UCP1 mRNA]] more ... CTD PMID:11742803 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione multiple interactions ISO RGD:2184 6480464 bisindolylmaleimide I inhibits the reaction [[Phenylephrine co-treated with Adenosine Triphosphate] results in increased secretion of AVP protein] CTD PMID:11102496 5'-phosphopyridoxal-6-azobenzene-2,4-disulfonic acid multiple interactions ISO RGD:2184 6480464 pyridoxal phosphate-6-azophenyl-2' more ... CTD PMID:11102496 6-oxoprostaglandin F1alpha increases abundance ISO RGD:2184 6480464 AVP protein results in increased abundance of 6-Ketoprostaglandin F1 alpha CTD PMID:4030047 6-oxoprostaglandin F1alpha multiple interactions ISO RGD:2184 6480464 Dexamethasone inhibits the reaction [AVP protein results in increased abundance of 6-Ketoprostaglandin F1 alpha] CTD PMID:4030047 actinomycin D multiple interactions ISO RGD:2184 6480464 Dactinomycin inhibits the reaction [[Phenylephrine co-treated with Adenosine Triphosphate] results in increased secretion of AVP protein] CTD PMID:11102496 all-trans-retinoic acid increases expression EXP 6480464 Tretinoin results in increased expression of AVP mRNA CTD PMID:17069763 ammonium chloride affects expression ISO RGD:2184 6480464 Ammonium Chloride affects the expression of AVP mRNA CTD PMID:16483693 apomorphine increases expression ISO RGD:68968 6480464 Apomorphine results in increased expression of AVP protein CTD PMID:16575035 apomorphine multiple interactions ISO RGD:68968 6480464 Metoclopramide inhibits the reaction [Apomorphine results in increased expression of AVP protein] CTD PMID:16575035 arachidonic acid increases abundance ISO RGD:2184 6480464 AVP protein results in increased abundance of Arachidonic Acid CTD PMID:11356622 Aroclor 1254 decreases secretion ISO RGD:2184 6480464 Chlorodiphenyl (54% Chlorine) results in decreased secretion of AVP protein CTD PMID:17434953 Aroclor 1254 multiple interactions ISO RGD:2184 6480464 Chlorodiphenyl (54% Chlorine) inhibits the reaction [Sodium Chloride, Dietary results in increased expression of AVP mRNA], Chlorodiphenyl (54% Chlorine) inhibits the reaction [Sodium Chloride, Dietary results in increased expression of AVP protein] CTD PMID:28579251 ATP increases secretion ISO RGD:2184 6480464 Adenosine Triphosphate results in increased secretion of AVP protein CTD PMID:11102496 ATP multiple interactions ISO RGD:2184 6480464 Adenosine Triphosphate promotes the reaction [Phenylephrine results in increased secretion of AVP protein] more ... CTD PMID:11102496 benzo[a]pyrene increases expression ISO RGD:2184 6480464 Benzo(a)pyrene results in increased expression of AVP mRNA CTD PMID:21839799 benzo[a]pyrene multiple interactions EXP 6480464 Benzo(a)pyrene affects the reaction [AHR protein binds to AVP promoter] CTD PMID:19654925 bis(2-ethylhexyl) phthalate affects expression ISO RGD:2184 6480464 Diethylhexyl Phthalate affects the expression of AVP mRNA CTD PMID:28871463 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of AVP mRNA CTD PMID:22707478 bisphenol A decreases expression ISO RGD:2184 6480464 bisphenol A results in decreased expression of AVP mRNA CTD PMID:25181051 BQ 123 multiple interactions ISO RGD:2184 6480464 cyclo(Trp-Asp-Pro-Val-Leu) inhibits the reaction [Doxorubicin results in increased expression of AVP protein] CTD PMID:18516097 butan-1-ol multiple interactions ISO RGD:2184 6480464 1-Butanol inhibits the reaction [AVP protein results in increased abundance of Calcium] CTD PMID:11356622 C60 fullerene decreases expression ISO RGD:2184 6480464 fullerene C60 results in decreased expression of AVP mRNA CTD PMID:19167457 cadmium dichloride increases expression ISO RGD:2184 6480464 Cadmium Chloride results in increased expression of AVP mRNA CTD PMID:21297351 cadmium dichloride multiple interactions EXP 6480464 cyanidin 3-O-glucoside inhibits the reaction [Cadmium Chloride results in increased expression of AVP mRNA] CTD PMID:31014900 cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of AVP mRNA CTD PMID:31014900 calcium atom multiple interactions ISO RGD:2184 6480464 1-Butanol inhibits the reaction [AVP protein results in increased abundance of Calcium] more ... CTD PMID:11356622 more ... calcium atom increases uptake ISO RGD:2184 6480464 AVP protein results in increased uptake of Calcium CTD PMID:9446840 calcium atom increases abundance ISO RGD:2184 6480464 AVP protein results in increased abundance of Calcium CTD PMID:11356622 , PMID:21039959 calcium(0) multiple interactions ISO RGD:2184 6480464 1-Butanol inhibits the reaction [AVP protein results in increased abundance of Calcium] more ... CTD PMID:11356622 more ... calcium(0) increases uptake ISO RGD:2184 6480464 AVP protein results in increased uptake of Calcium CTD PMID:9446840 calcium(0) increases abundance ISO RGD:2184 6480464 AVP protein results in increased abundance of Calcium CTD PMID:11356622 , PMID:21039959 carvedilol decreases expression ISO RGD:68968 6480464 carvedilol results in decreased expression of AVP protein CTD PMID:12523682 carvedilol multiple interactions ISO RGD:2184 6480464 carvedilol inhibits the reaction [AVP protein results in increased import of and results in increased abundance of Calcium] CTD PMID:14711191 chlorpromazine increases expression ISO RGD:68968 6480464 Chlorpromazine results in increased expression of AVP protein CTD PMID:3567260 chlorpromazine multiple interactions ISO RGD:2184 6480464 Chlorpromazine inhibits the reaction [Lithium results in increased expression of AVP protein] CTD PMID:3976404 chlorpropamide decreases secretion ISO RGD:68968 6480464 Chlorpropamide results in decreased secretion of AVP protein modified form CTD PMID:5029389 chromium atom multiple interactions ISO RGD:2184 6480464 Chromium affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium] more ... CTD PMID:9446840 chromium(3+) multiple interactions ISO RGD:2184 6480464 Chromium affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium] more ... CTD PMID:9446840 clonidine increases expression ISO RGD:2184 6480464 Clonidine results in increased expression of AVP protein CTD PMID:7400963 clonidine (amino form) increases expression ISO RGD:2184 6480464 Clonidine results in increased expression of AVP protein CTD PMID:7400963 clonidine (imino form) increases expression ISO RGD:2184 6480464 Clonidine results in increased expression of AVP protein CTD PMID:7400963 cyanamide multiple interactions ISO RGD:2184 6480464 [Ethanol co-treated with Cyanamide] results in increased expression of AVP mRNA CTD PMID:11139417 cyanamide increases expression ISO RGD:2184 6480464 Cyanamide results in increased expression of AVP mRNA CTD PMID:10718921 , PMID:10978654 cyanidin 3-O-beta-D-glucoside multiple interactions EXP 6480464 cyanidin 3-O-glucoside inhibits the reaction [Cadmium Chloride results in increased expression of AVP mRNA] CTD PMID:31014900 desflurane multiple interactions ISO RGD:68968 6480464 [Propofol co-treated with desflurane] results in increased expression of AVP protein CTD PMID:8017643 dexamethasone multiple interactions ISO RGD:2184 6480464 Dexamethasone inhibits the reaction [AVP protein results in increased abundance of 6-Ketoprostaglandin F1 alpha] more ... CTD PMID:2271928 more ... dexamethasone increases activity ISO RGD:2184 6480464 Dexamethasone results in increased activity of AVP protein CTD PMID:3346065 , PMID:4030047 doxorubicin multiple interactions ISO RGD:2184 6480464 cyclo(Trp-Asp-Pro-Val-Leu) inhibits the reaction [Doxorubicin results in increased expression of AVP protein] CTD PMID:18516097 doxorubicin increases expression ISO RGD:2184 6480464 Doxorubicin results in increased expression of AVP protein CTD PMID:18516097 EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor decreases expression ISO RGD:2184 6480464 Angiotensin-Converting Enzyme Inhibitors results in decreased expression of AVP protein CTD PMID:1773493 enalapril multiple interactions ISO RGD:2184 6480464 Enalapril promotes the reaction [Dexamethasone results in increased activity of AVP protein] CTD PMID:3346065 ethanol multiple interactions ISO RGD:2184 6480464 [Cholesterol, Dietary co-treated with Ethanol] results in decreased expression of AVP mRNA, [Ethanol co-treated with Cyanamide] results in increased expression of AVP mRNA CTD PMID:11139417 , PMID:22384198 ethanol decreases expression ISO RGD:2184 6480464 Ethanol results in decreased expression of AVP mRNA CTD PMID:21533237 fluoxetine decreases expression ISO RGD:2184 6480464 Fluoxetine results in decreased expression of AVP mRNA CTD PMID:17033635 fluvoxamine increases expression ISO RGD:68968 6480464 Fluvoxamine results in increased expression of AVP protein CTD PMID:11195401 folic acid decreases expression EXP 6480464 Folic Acid results in decreased expression of AVP mRNA CTD PMID:25006883 furan decreases expression ISO RGD:2184 6480464 furan results in decreased expression of AVP mRNA CTD PMID:25539665 Hexamethonium multiple interactions ISO RGD:2184 6480464 Hexamethonium promotes the reaction [Dexamethasone results in increased activity of AVP protein] CTD PMID:3346065 hydrochlorothiazide affects secretion ISO RGD:68968 6480464 Hydrochlorothiazide affects the secretion of AVP protein CTD PMID:6635723 hydroxyflutamide affects expression ISO RGD:2184 6480464 hydroxyflutamide affects the expression of AVP mRNA CTD PMID:20810896 ifosfamide multiple interactions ISO RGD:68968 6480464 [Ifosfamide co-treated with Mesna] results in increased expression of AVP protein CTD PMID:2261371 indometacin decreases secretion ISO RGD:68968 6480464 Indomethacin results in decreased secretion of AVP protein CTD PMID:16133044 isoflurane multiple interactions ISO RGD:68968 6480464 [Labetalol co-treated with Isoflurane] results in increased expression of AVP protein CTD PMID:1897344 labetalol multiple interactions ISO RGD:68968 6480464 [Labetalol co-treated with Isoflurane] results in increased expression of AVP protein CTD PMID:1897344 linsidomine increases expression ISO RGD:2184 6480464 linsidomine results in increased expression of AVP mRNA CTD PMID:10460269 lipopolysaccharide affects expression EXP 6480464 Lipopolysaccharides affects the expression of AVP mRNA CTD PMID:15667454 lithium atom increases expression ISO RGD:2184 6480464 Lithium results in increased expression of AVP protein CTD PMID:3976404 lithium atom affects expression ISO RGD:2184 6480464 Lithium affects the expression of AVP protein CTD PMID:2454589 lithium atom multiple interactions ISO RGD:2184 6480464 Chlorpromazine inhibits the reaction [Lithium results in increased expression of AVP protein] CTD PMID:3976404 lithium chloride increases expression ISO RGD:2184 6480464 Lithium Chloride results in increased expression of AVP mRNA, Lithium Chloride results in increased expression of AVP protein CTD PMID:9406968 lithium hydride affects expression ISO RGD:2184 6480464 Lithium affects the expression of AVP protein CTD PMID:2454589 lithium hydride increases expression ISO RGD:2184 6480464 Lithium results in increased expression of AVP protein CTD PMID:3976404 lithium hydride multiple interactions ISO RGD:2184 6480464 Chlorpromazine inhibits the reaction [Lithium results in increased expression of AVP protein] CTD PMID:3976404 lithium(1+) increases expression ISO RGD:2184 6480464 Lithium results in increased expression of AVP protein CTD PMID:3976404 lithium(1+) affects expression ISO RGD:2184 6480464 Lithium affects the expression of AVP protein CTD PMID:2454589 lithium(1+) multiple interactions ISO RGD:2184 6480464 Chlorpromazine inhibits the reaction [Lithium results in increased expression of AVP protein] CTD PMID:3976404 Mesna multiple interactions ISO RGD:68968 6480464 [Ifosfamide co-treated with Mesna] results in increased expression of AVP protein CTD PMID:2261371 methamphetamine multiple interactions ISO RGD:2184 6480464 [Methamphetamine co-treated with SCH 23390] affects the expression of AVP mRNA CTD PMID:19564919 methamphetamine affects expression ISO RGD:2184 6480464 Methamphetamine affects the expression of AVP mRNA CTD PMID:19564919 methotrexate increases secretion ISO RGD:68968 6480464 Methotrexate results in increased secretion of AVP protein CTD PMID:3176582 metoclopramide multiple interactions ISO RGD:68968 6480464 Metoclopramide inhibits the reaction [Apomorphine results in increased expression of AVP protein] CTD PMID:16575035 microcystin RR increases expression EXP 6480464 microcystin RR results in increased expression of AVP protein CTD PMID:28330766 naloxone decreases secretion ISO RGD:68968 6480464 Naloxone results in decreased secretion of AVP protein CTD PMID:6850280 Nicardipine multiple interactions ISO RGD:2184 6480464 Nicardipine inhibits the reaction [AVP protein results in increased import of and results in increased abundance of Calcium] CTD PMID:14711191 nicotine decreases expression EXP 6480464 Nicotine results in decreased expression of AVP mRNA CTD PMID:17456735 nicotine decreases expression ISO RGD:2184 6480464 Nicotine results in decreased expression of AVP mRNA CTD PMID:28555334 nicotine increases secretion ISO RGD:2184 6480464 Nicotine results in increased secretion of AVP protein alternative form CTD PMID:3681699 nifedipine multiple interactions ISO RGD:2184 6480464 Nifedipine inhibits the reaction [AVP protein results in increased import of and results in increased abundance of Calcium] CTD PMID:14711191 nitric oxide affects metabolic processing ISO RGD:2184 6480464 AVP protein affects the metabolism of Nitric Oxide CTD PMID:21171372 nitric oxide increases expression ISO RGD:2184 6480464 Nitric Oxide results in increased expression of AVP mRNA CTD PMID:10460269 nitric oxide multiple interactions ISO RGD:2184 6480464 IL1B protein affects the reaction [AVP protein affects the metabolism of Nitric Oxide] CTD PMID:21171372 oryzalin decreases activity EXP 6480464 oryzalin results in decreased activity of AVP protein CTD PMID:9443610 phenylephrine multiple interactions ISO RGD:2184 6480464 Adenosine Triphosphate promotes the reaction [Phenylephrine results in increased secretion of AVP protein] more ... CTD PMID:11102496 , PMID:2271928 phenylephrine increases secretion ISO RGD:2184 6480464 Phenylephrine results in increased secretion of AVP protein CTD PMID:11102496 , PMID:2271928 phosphatidic acid increases abundance ISO RGD:2184 6480464 AVP protein results in increased abundance of Phosphatidic Acids CTD PMID:11356622 phosphatidic acid multiple interactions ISO RGD:2184 6480464 2-(4-amylcinnamoyl)amino-4-chlorobenzoic acid inhibits the reaction [AVP protein results in increased abundance of Phosphatidic Acids] CTD PMID:11356622 prazosin increases expression ISO RGD:2184 6480464 Prazosin results in increased expression of AVP protein CTD PMID:1791990 progesterone decreases expression ISO RGD:2184 6480464 Progesterone results in decreased expression of AVP protein CTD PMID:16454802 propofol multiple interactions ISO RGD:68968 6480464 [Propofol co-treated with desflurane] results in increased expression of AVP protein CTD PMID:8017643 prostaglandin E2 increases abundance ISO RGD:2184 6480464 AVP protein results in increased abundance of Dinoprostone CTD PMID:4030047 prostaglandin E2 multiple interactions ISO RGD:2184 6480464 Dexamethasone inhibits the reaction [AVP protein results in increased abundance of Dinoprostone] CTD PMID:4030047 SCH 23390 affects expression ISO RGD:2184 6480464 SCH 23390 affects the expression of AVP mRNA CTD PMID:19564919 SCH 23390 multiple interactions ISO RGD:2184 6480464 [Methamphetamine co-treated with SCH 23390] affects the expression of AVP mRNA CTD PMID:19564919 scopolamine multiple interactions ISO RGD:2184 6480464 [[[AVP binds to and results in increased activity of AVPR1A protein] which results in increased abundance of Calcium] which results in increased activity of CHRM1 protein] which results in decreased susceptibility to Scopolamine CTD PMID:11553362 sodium chloride increases expression ISO RGD:2184 6480464 Sodium Chloride results in increased expression of AVP mRNA CTD PMID:19463813 sodium chloride increases expression ISO RGD:68968 6480464 Sodium Chloride results in increased expression of AVP protein CTD PMID:7923825 Tesaglitazar increases expression ISO RGD:2184 6480464 tesaglitazar results in increased expression of AVP mRNA CTD PMID:21515302 testosterone affects expression ISO RGD:2184 6480464 Testosterone affects the expression of AVP mRNA CTD PMID:20810896 tris(picolinato)chromium multiple interactions ISO RGD:2184 6480464 chromium tripicolinate affects the reaction [[AVP protein results in increased uptake of Calcium] which results in increased secretion of Calcium] more ... CTD PMID:9446840 urea increases transport ISO RGD:2184 6480464 AVP protein results in increased transport of Urea CTD PMID:7611462 valproic acid increases methylation ISO RGD:68968 6480464 Valproic Acid results in increased methylation of AVP gene CTD PMID:29154799 vincristine increases expression ISO RGD:68968 6480464 Vincristine results in increased expression of AVP protein CTD PMID:4356234
Biological Process ERK1 and ERK2 cascade ISO UniProtKB:P01185 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 grooming behavior ISO RGD:2184 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 locomotory behavior ISO RGD:2184 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 maternal aggressive behavior ISO RGD:2184 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 maternal behavior ISO RGD:2184 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 multicellular organismal water homeostasis ISO RGD:2184 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 negative regulation of apoptotic process ISO UniProtKB:P01185 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process ISO UniProtKB:P01185 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 negative regulation of female receptivity ISO RGD:2184 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 negative regulation of release of cytochrome c from mitochondria ISO UniProtKB:P01185 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 negative regulation of transmission of nerve impulse ISO RGD:2184 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 penile erection ISO RGD:2184 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 positive regulation of cell growth ISO RGD:2184 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 positive regulation of cell population proliferation ISO RGD:2184 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 positive regulation of cellular pH reduction ISO RGD:2184 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 positive regulation of cytosolic calcium ion concentration ISO RGD:2184 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 positive regulation of gene expression ISO UniProtKB:P01185 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 positive regulation of glutamate secretion ISO RGD:2184 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 positive regulation of peptidyl-serine phosphorylation ISO UniProtKB:P01185 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 positive regulation of prostaglandin biosynthetic process ISO RGD:2184 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 positive regulation of systemic arterial blood pressure ISO RGD:2184 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 positive regulation of vasoconstriction ISO RGD:2184 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 protein kinase C signaling ISO UniProtKB:P01185 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 regulation of blood vessel diameter IEA UniProtKB-KW:KW-0838 2290270 UniProtKB GO_REF:0000004, MGI:MGI:1354194 regulation of renal sodium excretion ISO RGD:2184 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 signal transduction ISO UniProtKB:P01185 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 social behavior ISO RGD:2184 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 vasoconstriction IEA UniProtKB-KW:KW-0839 2290270 UniProtKB GO_REF:0000004, MGI:MGI:1354194 Cellular Component dendrite ISO RGD:2184 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 extracellular region IEA InterPro:IPR000981 more ... 2290270 UniProtKB GO_REF:0000002, MGI:MGI:2152098 extracellular region IEA UniProtKB-KW:KW-0964 2290270 UniProtKB GO_REF:0000004, MGI:MGI:1354194 extracellular space ISO RGD:2184 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 extracellular space IBA PANTHER:PTN002617858 more ... 2290270 (PMID:21873635) GO_Central PMID:21873635 secretory granule ISO RGD:2184 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 secretory granule IBA PANTHER:PTN002617858 more ... 2290270 (PMID:21873635) GO_Central PMID:21873635 Molecular Function cysteine-type endopeptidase inhibitor activity involved in apoptotic process ISO UniProtKB:P01185 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 hormone activity IEA UniProtKB-KW:KW-0372 2290270 UniProtKB GO_REF:0000004, MGI:MGI:1354194 neurohypophyseal hormone activity IEA InterPro:IPR000981 more ... 2290270 UniProtKB GO_REF:0000002, MGI:MGI:2152098 neuropeptide hormone activity ISO RGD:2184 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 neuropeptide hormone activity IBA PANTHER:PTN000913415 more ... 2290270 (PMID:21873635) GO_Central PMID:21873635 neuropeptide hormone activity ISO UniProtKB:P01185 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 protein kinase activity ISO UniProtKB:P01185 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 V1A vasopressin receptor binding ISO RGD:2184 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 V1A vasopressin receptor binding IBA PANTHER:PTN001706302 more ... 2290270 (PMID:21873635) GO_Central PMID:21873635 V1A vasopressin receptor binding ISO UniProtKB:P01185 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 V1B vasopressin receptor binding ISO RGD:2184 2290270 RGD GO_REF:0000096, MGI:MGI:4417868
Gene-Chemical Interaction Annotations
