Strain Report - Rat Genome Database

Send us a Message

Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

Strain: ACI.Cg.-Cdkn1bem4Musc

Symbol: ACI.Cg.-Cdkn1bem4Musc
Strain: ACI.Cg.-Cdkn1bem4
Substrain: Musc
RGD ID: 126928150
Citation ID: RRID:RGD_126928150
Ontology ID: RS:0005011
Alleles: Cdkn1bem4Musc
Also known as: DEL-65; ACI.SD-Cdkn1bem4MUSC
Type: mutant
Source: Transgenic and Gene Function Core, Medical University of South Carolina, Charleston, South Carolina, United States of America
Origin: The CRISPR-Cas9 system targeted to exon 2 of the rat Cdkn1b was injected to zygotes derived from the Sprague-Dawley outbred rat strain. Two mutations with the highest potential impact on Cdkn1b function were transferred through the germline showing a 32-bp deletion (DEL-32, em1Musc) and a 65-bp deletion (DEL-65, em2Musc), both disrupting the open reading frame of the Cdkn1b gene. The selected mutations were breded to the ACI inbred strain for future study. This mutant strain ACI.Cg.-Cdkn1bem4Musc harbors 65-bp deletion of Cdkn1b exhibits same phenotype as the em1Musc with 32-bp deletion
Genetic Status: Homozygous
Last Known Status: Unknown
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24167,760,067 - 167,765,177RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.04168,689,043 - 168,694,159RGD_MAPPER_PIPELINERnor6.0
Rnor_5.04232,962,218 - 232,967,323RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.44171,841,705 - 171,846,506RGD_MAPPER_PIPELINERGSC3.4



Additional Information